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Original Articles
Association between single-person household wage workers in South Korea and insomnia symptoms: the 6th Korean Working Conditions Survey (KWCS)
Yoon Ho Lee, Yong-Jin Lee, Eun-Chul Jang, Young-Sun Min, Soon-Chan Kwon
Ann Occup Environ Med 2024;36:e25.   Published online September 6, 2024
DOI: https://doi.org/10.35371/aoem.2024.36.e25
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background
The rise in single-person households is a global phenomenon with well-documented implications for both physical and mental well-being. However, there remains a scarcity of studies focusing specifically on the health impacts of single-person households on workers. This study aims to address this gap by comparing insomnia symptoms between single- and multi-person household workers, shedding light on the health implications of household composition.
Methods
This study utilized data from the Sixth Korean Working Conditions Survey. Insomnia symptoms were categorized into normal sleep and insomnia symptom groups utilizing the 3-item Minimal Insomnia Symptom Scale. Multiple logistic regression analysis was employed to examine the association between single-person household wage workers and insomnia symptoms.
Results
In comparison to wage workers from multi-person households, those from single-person households exhibited heightened risks of reporting insomnia symptoms. In the fully adjusted model, the odds ratios for symptoms of insomnia among single-person household wage workers was 1.173 (95% confidence interval: 1.020–1.349).
Conclusions
This study underscores that single-person household wage workers in Korea face an elevated risk of insomnia symptoms compared to their counterparts in multi-person households.

목적
기존 연구에 의하면 1인 가구와 건강 문제는 부정적인 연관성을 보이는 것으로 알려져 있으나 1인 가구 임금 근로자들에 대한 연구는 부족해 보인다. 이에 임금 근로자들을 대상으로 1인 가구의 불면증 증상의 실태를 파악하고 다인 가구 임금 근로자들과 비교하여 1인 가구 근로자가 건강에 어떠한 영향을 미치는지 연구해보고자 한다.
방법
이 연구는 제6차 근로환경조사의 원시자료를 이용한 단면 연구이다. 불면증 증상의 경우 Minimal Insomnia Symptom Scale (MISS)를 사용하여 평가되었다. 다인 가구 임금 근로자군과 비교했을 때 1인 가구 임금 근로자군과 불면증 증상 간의 연관성을 연구하기 위해 다중 로지스틱 회귀분석을 실시하였다.
결과
다인 가구 임금 근로자군과 비교했을 때 1인 가구 임금 근로자군의 불면증 증상에 대한 교차비(OR)은 1.173 (95% confidence interval [CI]: 1.020-1.349)로 나타났다.
결론
연구 결과 한국의 1인 가구 임금 근로자는 다인 가구 임금 근로자에 비해 불면증 증상을 보일 위험이 높은 것으로 나타났다. 1인 가구 근로자의 증가 추세는 근로자의 건강에 영향을 미치는 요인으로서 관심이 필요할 것으로 생각된다.
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The association of shift work and TyG index among male workers in a chemical plant of Korea: a cross-sectional study
Gwangin Baek, Yong-Jin Lee, Soon-Chan Kwon, Young-Sun Min, Jisuk Yun, Tae Jin Ahn, Eun-Chul Jang
Ann Occup Environ Med 2024;36:e18.   Published online July 10, 2024
DOI: https://doi.org/10.35371/aoem.2024.36.e18
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Disturbance of circadian rhythms caused by shift work has adverse effects on insulin resistance. Many previous studies have confirmed that shift work and insulin resistance are related using homeostasis model assessment-insulin resistance, one of the insulin resistance indicators. However, the triglycerides and glucose index (TyG index) has recently been studied as an insulin resistance indicator. The aim of this study is to investigate the association of shift work and TyG index, one of the indirect indicators of insulin resistance, using results of health checkups in one workplace.

Methods

Based on medical examination data collected in February 2019, a total of 3,794 subjects from one chemical plant in Korea were selected for this study. Cut-off value of TyG index for predicting development of diabetes mellitus (DM) was 4.69. A multiple logistic regression analysis was performed after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease.

Results

As a result of logistic regression analysis, compared to day workers, odds ratio (OR) with a TyG index above cut-off value for predicting development of DM in shift workers was 1.220 after adjusting for age, employment period, obesity, abdominal obesity, smoking, drinking, physical activity, hypertension, stroke, heart disease (Model 1, OR: 1.276; 95% confidence interval [CI]: 1.099–1.482; Model 2, OR: 1.232; 95% CI: 1.055–1.438; Model 3, OR: 1.220, 95% CI: 1.030–1.444).

Conclusions

There was a significant association between shift work and TyG index among male workers in a chemical plant. More research studies on the association between shift work and TyG index are needed in the future.

한국의 한 화학 공장의 남성 근로자들에서 교대 근무와 TyG index의 관련성
목적
교대 근무와 인슐린 저항성이 관련이 있다는 연구가 기존에 있었으나, 인슐린 저항성의 지표로 기존에는 homeostasis model assessment-insulin resistance (HOMA-IR)을 이용하였다. 하지만 최근, 인슐린 저항성 지표 중 하나인 Triglycerides and Glucose (TyG) index가 당뇨병 발생의 예측을 위한 지표로서 기존 다른 인슐린 저항성 지표보다 우수하다는 연구들이 발표되었다. 이에 본 연구는 한국의 한 화학공장의 근로자들을 대상으로 교대근무와 당뇨병 발생의 예측인자로서의 TyG index의 관련성을 확인하고자 하였다.
방법
2019년 2월 한국의 한 화학공장 사업장에서 실시된 건강검진 기록을 활용하여 총 3,794명의 자료를 대상으로 자료를 수집하였다. 변수로 대상자의 일반적 특성 및 교대근무 여부, 근무 기간 등 직업적 특성이 포함되었다. 기존 연구를 토대로, 당뇨병 발생의 예측을 위한 TyG index의 컷오프 값은 4.69로 설정하였다. 다중 로지스틱 회귀 분석을 사용하여 교대 근무와 TyG index 사이의 연관성을 조사하였다.
결과
교대 근무와 TyG index 사이에 유의미한 연관성이 있었다. (OR 1.220, 95% CI 1.030-1.444)
결론
교대 근무와 TyG index 사이에 유의미한 연관성이 있었다. TyG index가 당뇨병 발생의 예측인자로서 가치가 있다는 근거를 토대로 하여서, 교대 근로자들의 당뇨병 발생의 관리를 위해서 TyG index를 이용하는 것을 고려할 필요가 있을 것이다.
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Relationship between job stress and impaired fasting glucose in male steel industry workers: a cross-sectional study
Hyun-Kyo Lee, Inho Lee, Jisuk Yun, Yong-Jin Lee, Eun-Chul Jang, Young-Sun Min, Soon-Chan Kwon
Ann Occup Environ Med 2023;35:e12.   Published online June 2, 2023
DOI: https://doi.org/10.35371/aoem.2023.35.e12
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

The purpose of this study is to investigate the relationship between job stress and impaired fasting glycemia (IFG) of male workers in a manufacturing industry.

Methods

Data were collected from 5,886 male workers in a manufacturing industry who participated in the medical examination from June 19 to August 14, 2020 through self-reported questionnaires. The general characteristics of the subjects, shift work, high blood pressure, dyslipidemia, and job stress were included. Job stress was measured using the Korean Occupational Stress Scale (KOSS) consisting of 8 items and 43 questions. Multivariable logistic regression analysis was used to investigate the IFG association with job stress.

Results

Among the various factors that can cause job stress, only high job demand was associated with a risk of IFG (odds ratio, 1.43; 95% confidence interval, 1.13–1.82) especially in non-shift worker. For all other factors, no statistically significant results were obtained.

Conclusions

In this study of male workers engaged in the Korean steel manufacturing industry, the 'job demand' item among job stress of non-shift worker was related to IFG.

철강 공장에 근무하는 남성 근로자의 직무 스트레스와 공복혈당장애와의 관계: 단면연구
목적
제2형 당뇨와 직무 스트레스와의 관계를 다룬 여러 연구가 있었으나 공복혈당장애와의 관계를 조사한 연구 결과는 존재하지 않았다. 본 연구는 단일 철강 사업장에서 직무스트레스와 공복혈당장애의 관련성을 확인하되 한국형 직무스트레스 각각 항목과의 연관성을 파악하고자 하였다.
방법
2020년 6월 19일부터 8월 14일까지 건강검진에 참여한 제조업 남성 근로자 5,886명을 대상으로 자체 보고 설문지를 통해 자료를 수집하였다. 변수로 대상자의 일반적인 특성 및 교대근무, 재직년수, 고혈압, 이상지질혈증, 직무스트레스 점수가 포함되었다. 직무스트레스는 8개 항목과 43개 질문으로 구성된 한국직업스트레스척도(KOSS)를 이용하여 측정되었다. 다중 로지스틱 회귀 분석을 사용하여 직무 스트레스와 IFG의 연관성을 조사하였다.
결과
직무스트레스를 유발할 수 있는 다양한 요인 중, 비 야간작업자의 높은 직무요구도만이 IFG(OR 1.43, 95% CI 1.13-1.82)의 위험 증가와 관련이 있었다. 다른 모든 요인의 경우 통계적으로 유의한 결과가 얻어지지 않았다.
결론
철강 제조업에 종사하는 남성 근로자들을 대상으로 한 본 연구에서 직무 스트레스 중 ‘직무 요구’ 항목은 비 야간작업자의 공복혈당장애와 관련이 있었다. 향후 다양한 직업군을 대상으로 한 후속 연구가 필요할 것이다.
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The association of perfluoroalkyl substances (PFAS) exposure and kidney function in Korean adolescents using data from Korean National Environmental Health Survey (KoNEHS) cycle 4 (2018–2020): a cross-sectional study
Jisuk Yun, Eun-Chul Jang, Soon-Chan Kwon, Young-Sun Min, Yong-Jin Lee
Ann Occup Environ Med 2023;35:e5.   Published online March 15, 2023
DOI: https://doi.org/10.35371/aoem.2023.35.e5
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Perfluoroalkyl substances (PFAS) are chemicals widely used in various products in everyday life. Due to its unique strong binding force, the half-life of PFAS is very long, so bioaccumulation and toxicity to the human body are long-standing concerns. In particular, effects on kidney function have recently emerged and there are no studies on the effect of PFAS on kidney function through epidemiological investigations in Korea. From 2018 to 2020, the Korean National Environmental Health Survey (KoNEHS) cycle 4, conducted an epidemiological investigation on the blood concentration of PFAS for the first time in Korea. Based on this data, the relationship between PFAS blood concentration and kidney function was analyzed for adolescents.

Methods

We investigated 5 types of PFAS and their total blood concentration in 811 middle and high school students, living in Korea and included in KoNEHS cycle 4, and tried to find changes in kidney function in relation to PFAS concentration. After dividing the concentration of each of the 5 PFAS and the total concentration into quartiles, multivariable linear regression was performed to assess the correlation with kidney function. The bedside Schwartz equation was used as an indicator of kidney function.

Results

As a result of multivariable linear regression, when observing a change in kidney function according to the increase in the concentration of each of the 5 PFAS and their total, a significant decrease in kidney function was confirmed in some or all quartiles.

Conclusions

In this cross-sectional study of Korean adolescents based on KoNEHS data, a negative correlation between serum PFAS concentration and kidney function was found. A well-designed longitudinal study and continuous follow-up are necessary.

제 4기 국민환경보건 기초조사(2018-2020) 자료를 바탕으로 한 대한민국 청소년의 과불화 화합물 노출과 신장기능과의 상관관계 연구
목적
과불화 화합물은 일상생활에서 다양한 제품에 널리 쓰이는 화학물질이다. 특유의 강한 결합력으로 인한 반감기가 매우 길기 때문에 이로 인한 생물농축과 인체에 끼치는 독성작용은 오랫동안 큰 관심사이다. 최근에는 특히 신기능에 미치는 영향이 주목받고 있으나 국내에서는 대규모 역학조사를 통한 PFAS가 신기능에 미치는 영향에 대한 조사가 전무한 실정이다. 2018년부터 2020년까지 실시된 국민환경보건 기초조사는 국내 최초로 과불화 화합물의 혈중농도에 대한 대규모 역학조사를 실시했다. 이 자료를 바탕으로 국내 최초로 청소년을 대상으로 하여 과불화 화합물의 혈중농도와 신장기능의 관계를 분석하였다.
방법
제 4기 국민환경보건 기초조사에 포함된 국내에 거주하는 중, 고등학생 828명을 대상으로 5종의 과불화 화합물의 혈중 농도를 조사하고 농도에 따른 신장기능의 변화를 알아보고자 하였다. 5종의 과불화 화합물 각각의 농도와 총 합의 농도를 사분위수로 나눈 후 다중선형회귀분석을 실시하여 신기능과의 상관관계를 분석하였다.
결과
다중선형회귀분석 결과 5종의 과불화 화합물 각각의 농도와 총 합의 농도 증가에 따라 일부 또는 전체 사분위수에서 통계적으로 유의한 신장기능의 감소가 확인되었다.
결론
제 4기 국민환경보건 기초조사 자료를 바탕으로 한국 청소년을 대상으로 한 이번 단면연구에서는 혈중 과불화 화합물의 농도와 신기능 사이에 음의 상관관계가 있음을 발견하였다. 잘 설계된 종단연구와 지속적인 추적관찰이 필요하다.

Citations

Citations to this article as recorded by  
  • Association of Combined Per- and Polyfluoroalkyl Substances and Metals with Chronic Kidney Disease
    Issah Haruna, Emmanuel Obeng-Gyasi
    International Journal of Environmental Research and Public Health.2024; 21(4): 468.     CrossRef
  • Leveraging Machine Learning for a Comprehensive Assessment of PFAS Nephrotoxicity
    Anirudh Mazumder, Kapil Panda
    Advances in Science, Technology and Engineering Systems Journal.2024; 9(3): 62.     CrossRef
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The health effects of low blood lead level in oxidative stress as a marker, serum gamma-glutamyl transpeptidase level, in male steelworkers
Su-Yeon Lee, Yong-Jin Lee, Young-Sun Min, Eun-Chul Jang, Soon-Chan Kwon, Inho Lee
Ann Occup Environ Med 2022;34:e34.   Published online November 2, 2022
DOI: https://doi.org/10.35371/aoem.2022.34.e34
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

This study aimed to investigate the association between lead exposure and serum gamma-glutamyl transpeptidase (γGT) levels as an oxidative stress marker in male steelworkers.

Methods

Data were collected during the annual health examination of workers in 2020. A total of 1,654 steelworkers were selected, and the variables for adjustment included the workers’ general characteristics, lifestyle, and occupational characteristics. The association between the blood lead level (BLL) and serum γGT level was investigated by multiple linear and logistic regression analyses. The BLL and serum γGT values that were transformed into natural logarithms were used in multiple linear regression analysis, and the tertile of BLL was used in logistic regression analysis.

Results

The geometric mean of the participants’ BLLs and serum γGT level was 1.36 μg/dL and 27.72 IU/L, respectively. Their BLLs differed depending on age, body mass index (BMI), smoking status, drinking status, shift work, and working period, while their serum γGT levels differed depending on age, BMI, smoking status, drinking status, physical activity, and working period. In multiple linear regression analysis, the difference in models 1, 2, and 3 was significant, obtaining 0.326, 0.176, and 0.172 (all: p < 0.001), respectively. In the multiple linear regression analysis stratified according to drinking status, BMI, and age, BLLs were positively associated with serum γGT levels. Regarding the logistic regression analysis, the odds ratio of the third BLL tertile in models 1, 2, and 3 (for having an elevated serum γGT level within the first tertile reference) was 2.74, 1.83, and 1.81, respectively.

Conclusions

BLL was positively associated with serum γGT levels in male steelworkers even at low lead concentrations (< 5 μg/dL).

제철소 남성근로자들의 저농도 납노출이 산화스트레스 지표인 혈청 감마지티에 미치는 건강영향
목적
본 연구의 목적은 일개 제철소에 근무하는 남성 근로자들의 납 노출 수준과 산화스트레스 지표로서의 혈청 감마지티와의 연관성을 확인하는 것이다.
방법
본 연구는 2020년 시행된 근로자 건강검진 자료를 이용하였으며, 총 1,654명의 남성 근로자가 최종 연구대상으로 선정되었다. 일반적 특성, 생활양식 및 직업적 특성을 나타내는 변수를 설정하여 보정하였으며, 혈중납수준과 혈청 감마지티의 연관성을 알아보기 위해 다중선형회귀분석 및 로지스틱회귀분석을 실시하였다. 다중선형회귀분석에서는 자연로그로 변환된 혈중납 및 혈청 감마지티값을, 로지스틱회귀분석에서는 혈중납 3분위수를 이용하였다.
결과
연구대상자의 혈중납 및 혈청 감마지티의 기하평균은 각각 1.36 μg/dL, 27.72 IU/L 이었으며, 혈중납수준은 연령, 체질량지수, 흡연, 음주, 교대근무, 근무기간에 따라 차이가 있었고, 혈청 감마지티는 연령, 체질량지수, 흡연, 음주, 신체활동, 근무기간에 따라 차이를 보였다. 다중선형회귀분석에서는 모형 1,2,3 에서 혈중납수준과 혈청감마티지의 유의미한 연관성을 보여주었으며 (Model 1, β : 0.326, p < 0.001 ;Model 2, β: 0.176, p< 0.001;Model 3, β: 0.172 p< 0.001), 음주상태, 연령, 체질량지수, 음주 및 흡연 통합변수로 층화하여 분석하였을 때에도 혈중납수준과 혈청감마지티의 연관성은 유의하였다. 로지스틱회귀분석은 혈중납 3분위수와 혈청 감마지티 상승위험의 연관성을 보여주었다. (Model 1, OR: 2.74, 95% CI: 1.764.28 ;Model 2, OR: 1.83, 95%CI:1.132.95 ; Model 3, OR 1.81, 95%CI:1.122.92)
결론
일개 제철소 남성근로자를 대상으로 실시된 본 연구는 혈중납 5μg/dL 이하의 저농도 노출수준에서도 혈중납 수준과 혈청 감마지티 수치가 연관성이 있음을 보여준다.

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  • The Association Between Blood Lead Levels and Coronary Artery Calcium Score Determined by Using Coronary Computed Tomography Angiography
    Eunyoung Park, Suwhan Kim, Seunghyeon Cho, Hyeonjun Kim, Inho Jung, Jai-Dong Moon, Won-Ju Park
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
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Correlation between shift work and non-alcoholic fatty liver disease among male workers in the steel manufacturing company of Korea: a cross-sectional study
Kiseok Kim, Yong-Jin Lee, Soon-Chan Kwon, Young-Sun Min, Hyun Kyo Lee, Gwangin Baek, Sang Hyeon Kim, Eun-Chul Jang
Ann Occup Environ Med 2022;34:e33.   Published online November 2, 2022
DOI: https://doi.org/10.35371/aoem.2022.34.e33
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Circadian rhythm disturbance caused by shift work has adverse effects on the metabolic homeostasis of the liver. Disruption of the metabolic homeostasis of the liver causes fat accumulation in the liver. The aim of this study was to investigate the correlation between shift work and non-alcoholic fatty liver disease (NAFLD) among male workers in the steel manufacturing industry of Korea.

Methods

Based on medical examination data collected in June 2020, 2,511 male subjects from one steel manufacturing company in Korea were selected in total. NAFLD was evaluated using abdominal ultrasound, which was performed by two experienced radiologists. The multinomial logistic regression analysis was performed by adjusting for age, physical activity, smoking history, alcohol consumption, body mass index, waist circumference, blood pressure, blood glucose, lipidemia, liver function test, employment duration, and hepatotoxic materials exposure status.

Results

Compared to daytime workers, the odds ratio (OR) of moderate-severe NAFLD in shift workers was 1.449 (95% confidence interval [CI], 1.028–2.043). Compared to daytime workers, the ORs of moderate-severe NAFLD were significantly higher for the group that engaged in total shift work for more than 20 years (OR, 2.285; 95% CI, 1.051–4.970), the group that was not allowed to sleep during night shift work (OR, 1.463; 95% CI, 1.030–2.078), and the group that consumed food during night shift work (OR, 1.580; 95% CI, 1.093–2.284).

Conclusions

There was a correlation between shift work and moderate-severe NAFLD in male steel manufacturing workers. There will be a need for more research related to the correlation of shift work with steatohepatitis and cirrhosis in the future.

한국 철강 제조업 남성 근로자의 교대근무와 비알코올성 지방간 질환의 상관관계 연구 : 단면연구.
목적
교대근무로 인한 일주기 리듬 교란은 간의 신진대사 항상성에 부정적인 영향을 미친다. 간의 신진대사 항상성 교란은 간에 지방 축적을 일으킨다. 본 연구의 목적은 한국 철강 제조업 남성 근로자의 교대근무와 비알코올성 지방간 질환의 상관관계를 조사하는 것이다.
방법
2020년 6월 수집한 건강검진 자료를 바탕으로 국내 1개 철강 제조업 사업장에서 총 2,511명의 대상자를 선정하였다. 비알코올성 지방간은 두 명의 숙련된 방사선사가 수행한 복부 초음파를 기준으로 평가되었다. 연령, 신체활동, 흡연력, 알코올 소비량, 체질량 지수, 허리둘레, 혈압, 혈당, 지질혈증, 간 기능 검사, 근무 기간 및 간 독성 물질 노출 상태에 대한 보정을 시행한 다항 로지스틱 회귀분석을 실시하였다.
결과
주간 근로자 대비 교대 근무자의 중등도-고도 비알코올성 지방간의 오즈 비는 1.499 (95% 신뢰구간: 1.028-2.043)이었다. 총 교대근무 종사 기간 20년 이상인 군, 야간교대근무 중 수면이 불가능한 군, 그리고 야간교대근무 중 음식 섭취를 하는 군에서 주간 근로자 대비 통계적으로 유의미하게 큰 중등도-고도 비알코올성 지방간의 오즈 비를 보였다.
결론
교대근무는 한국 철강 제조업에 종사하는 남성 근로자의 중등도-고도 비알코올성 지방간과 상관관계가 있다. 앞으로 교대근무와 지방간염, 간경변과의 상관관계와 관련된 추가 연구가 필요할 것이다.

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  • Nonalcoholic Fatty Liver Disease in Shift Workers and Its Effect on Peripheral Nerve Conduction: A Cross-Sectional Study
    Dipali K Chatur, Saroj K Pati, Jayshri R Ghate, Rachita Nanda, Meenakshi Sinha, Kalpana Kodapi
    Cureus.2024;[Epub]     CrossRef
  • Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway
    Xinxing Wan, Linghao Wang, Md Asaduzzaman Khan, Lin Peng, Keke Zhang, Xiaoying Sun, Xuan Yi, Zhouqi Wang, Ke Chen
    Cell Death Discovery.2024;[Epub]     CrossRef
  • Inter-individual variations in circadian misalignment-induced NAFLD pathophysiology in mice
    Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, Isao Tokuda, Yoshiki Tsuchiya, Yuh Sasawaki, Atsushi Umemura, Naoko Masuzawa, Kazuya Yabumoto, Takashi Seya, Akira Sugimoto, Seung-Hee Yoo, Zheng Chen, Kazuhiro Yagita
    iScience.2024; 27(2): 108934.     CrossRef
  • Effects of Oat β-Glucan and Inulin on Alleviation of Nonalcoholic Steatohepatitis Aggravated by Circadian Disruption in C57BL/6J Mice
    Nelson Kei, Kam Kuen Cheung, Ka Lee Ma, Tsz Kwan Yau, Susana Lauw, Vincent Wai Sun Wong, Lijun You, Peter Chi Keung Cheung
    Journal of Agricultural and Food Chemistry.2024; 72(7): 3520.     CrossRef
  • Assessing Dust Emissions, Health Impacts, and Accident Risks in Prefabricated and Conventional Construction: A Comprehensive Comparative Study
    Louis Kumi, Jaewook Jeong, Jaemin Jeong
    Buildings.2023; 13(9): 2305.     CrossRef
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The acclimatization of Haenyeo to a cold environment and occupational characteristics evaluated by orexin and irisin levels
Inho Lee, Yong-Jin Lee, Eun-Chul Jang, Soon-Chan Kwon, Young-Sun Min, Jisuk Yun, Taehwan Park, Hye-Jin Lee, Eonah Choo, Jeong-Beom Lee
Ann Occup Environ Med 2022;34:e28.   Published online October 13, 2022
DOI: https://doi.org/10.35371/aoem.2022.34.e28
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Haenyeo is a woman who has the job of collecting seafood in the Jeju Sea at an average temperature of 13°C–14°C. The purpose of this study was to examine the cold acclimatization and occupational characteristics of Haenyeo through biomarkers such as orexin and irisin related to heat generation in the body.

Methods

Twenty-one Haenyeo and 25 people with similar age, body type, and body mass index were selected as the control group (Control G). In the cold exposure experiment, a climate chamber was set to 5°C and both feet were immersed in a 15°C water tank for 30 minutes. Tympanic temperature (Tty) and skin temperature (Tsk) were measured, and the mean body temperature (mTb) was calculated. Blood samples were collected before and immediately after the examination. Orexin and irisin levels were analyzed.

Results

Orexin levels were elevated after cold stimulation from 12.17 ± 4.44 to 12.95 ± 4.53 ng/mL (Haenyeo group [Haenyeo G], p < 0.01) and 10.37 ± 3.84 to 11.25 ± 4.02 ng/mL (Control G, p < 0.001). Irisin levels were elevated after cold stimulation from 4.83 ± 2.28 to 5.36 ± 2.23 ng/mL (Haenyeo G, p < 0.001) and 3.73 ± 1.59 to 4.18 ± 2.04 ng/mL (Control G, p < 0.001). The difference between Haenyeo G and Control G values in orexin and irisin appears not only in pre-exposure but also in post-exposure (p < 0.05).

Conclusions

Our experimental results suggest that Haenyeo G were relatively superior in cold tolerance to Control G under cold exposure conditions. Haenyeo’s cold acclimatization is due to the basic differences in pyrogens regarding body temperature control such as orexin and irisin. This means that Haenyeo are advantageous for cold survival.

해녀의 혈중 오렉신 및 이리신 수치를 통한 한랭환경 적응 및 직업적 특성에 관한 연구
목적
해녀는 산소공급장치 없이 바다에서 해산물을 채취하는 직업을 가진 여성으로 2016년 유네스코 인류무형문화유산에 '제주 해녀문화'로 등재됐다. 해녀 여성들은 제주 바다에서 평균 13~14°C의 온도에서 일하며 오랜 세월 동안 추운 환경 적응과 기후 적응의 환경 생리 반응을 발달시켰다. 본 연구의 목적은 체내 발열과 관련된 오렉신, 이리신 등의 생체지표를 통해 한랭적응시 체온유지에 사용되는 해녀의 한랭적응 및 직업적 특성을 조사하고자 하였다.
방법
해녀 21명 및 해녀와 유사한 연령과 체형, 체질량지수를 가진 25명을 선정하여 실험하였다. 한랭 부하 실험에서는 기후 챔버를 5°C로 설정하고 양발을 15°C의 물탱크에 30분간 담갔다. 고막 온도(Tty)와 피부 온도(Tsk)를 측정하고 평균 체온(mTb)을 계산하였다. 실험 전후로 혈액을 채취해 오렉신과 이리신 수치를 분석하였다.
결과
한랭 부하 실험 후 오렉신 수치는 해녀군은 12.17 ± 4.44 에서 12.95 ± 4.53 ng/mL (P < 0.01)으로, 대조군은 10.37 ± 3.84에서 11.25 ± 4.02 ng/mL(P < 0.001)으로 상승하였다. 이리신 수치도 해녀군은 4.83 ± 2.28에서 5.36 ± 2.23 ng/mL(P < 0.001)으로, 대조군은 3.73 ± 1.59에서 4.18 ± 2.04 ng/mL(P < 0.001)으로 상승하였다. 또한 실험 전 오렉신 및 이리신 수치가 대조군에 비해 해녀군에서 높았으며, 실험 후 대조군과 해녀군을 비교하였을 때에도 해녀군이 대조군에 비해 오렉신 및 이리신 수치가 유의미하게 높았음을 알 수 있다. (P < 0.05)
결론
저온 노출 조건에서 직업력 50년 이상인 해녀가 대조군에 비해 추위 내성이 높음을 알 수 있다. 본 연구에서 해녀의 한랭적응은 오렉신 및 이리신 등 발열에 관여하는 바이오마커의 기본적 차이가 존재하기 때문이라 설명된다. 따라서 해녀는 추위 생존에 있어 유리한 지위에 있다 할 것이다.
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Hospital admissions due to endocrine diseases in Korean male firefighters
Seunghoon Ryu, Yong-Jin Lee, Eun-Chul Jang, Soon-Chan Kwon, KiSeok Kim, Yeon-Soon Ahn, Young-Sun Min
Ann Occup Environ Med 2021;33:e32.   Published online October 28, 2021
DOI: https://doi.org/10.35371/aoem.2021.33.e32
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

The aim of this study was to investigate the relationship between occupational exposure to various hazards and hospital admission due to endocrine diseases in Korean male firefighters.

Methods

From 2000 to 2008, former and current male firefighters registered in the Korean National Emergency Management Agency were investigated based on their hospitalized health insurance admission data for the same period. Admission data for endocrine, nutritional, and metabolic diseases were obtained from the Korean National Health Insurance Service database. Standardized admission ratio (SAR) with reference to the general population of Korean men was analyzed.

Results

SAR for firefighters with endocrine, nutritional, and metabolic diseases was 0.56 (95% confidence interval [CI]: 0.49–0.65), which was significantly less than that of the general population of Korean men. For those with endocrine, nutritional, and metabolic diseases, SARs for those with a history of fire suppression tasks and those without experience of fire suppression tasks were 0.58 (95% CI: 0.49–0.68) and 0.53 (95% CI: 0.40–0.70), respectively.

Conclusions

The admission rate of Korean male firefighters due to endocrine, nutritional and metabolic diseases was significantly lower than that of the general Korean men population, the hazardous potential of endocrine disruptors remains an open question. Further studies of firefighters with longer follow-up are needed.

한국 남성 소방관에서 내분비 질환으로 인한 입원
목적
본 연구의 목적은 남성 소방관들을 대상으로 유해인자 노출과 내분비질환과의 관련성을 조사해보고자 하였다.
방법
2000년부터 2008년까지 소방방재청에 등록된 총 34,875명의 전·현직 남성 소방관들의 건강검진 자료와 동일 기간 건강보험 입원자료를 근간으로 전·현직 남성 소방관들에 대해 조사하였고, 이를 일반인구집단과 비교하여 표준화입원비를 분석하였다.
결과
내분비, 영양 및 대사질환의 표준화입원비는 0.56(95% 신뢰구간: 0.49-0.65)으로 우리나라 일반 남성들에 비하여 통계적으로 유의하게 적게 입원하였다. 또한, 화재진압 유무에 따라 분석하였을 때, 내분비, 영양 및 대사질환의 표준화입원비는 화재진압 유경력자는 0.58(95% 신뢰구간:0.49-0.68), 무경력자는 0.53(95% 신뢰구간: 0.40-0.70)으로 두 집단 모두 우리나라 일반 남성들에 비하여 통계적으로 유의하게 적게 입원하였다.
결론
우리나라 남성 소방관들의 내분비, 영양 및 대사질환의 표준화입원비는 우리나라 일반 남성에 비하여 통계적으로 유의하게 낮았다.
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Association between metabolic syndrome and shift work in chemical plant workers
Seong-Ryol Chai, Soon-Chan Kwon, Yong-Jin Lee, Eun-Chul Jang, Young-Sun Min, Su-yeon Lee
Ann Occup Environ Med 2021;33:e31.   Published online October 22, 2021
DOI: https://doi.org/10.35371/aoem.2021.33.e31
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

The study aimed to determine the association between shift work and metabolic syndrome and the prevalence of metabolic syndrome in the shift and day work groups among workers working in chemical plants.

Methods

Based on medical examination data collected in February 2019, 3,794 workers working at a chemical plant in Korea were selected. Multiple logistic regression analysis was performed by adjusting for age, sex, body mass index (BMI), drinking, exercise, smoking, employment period and organic compounds exposure.

Results

The prevalence of metabolic syndrome in the entire study group was 23.4%, and the prevalence and components of metabolic syndrome in shift worker; waist circumference were higher than those of day workers (84.77 ± 8.64 vs. 83.41 ± 9.42, p < 0.001), systolic blood pressure (129.89 ± 9.47 vs. 127.57 ± 9.47, p < 0.001), diastolic blood pressure (81.22 ± 7.59 vs. 79.34 ± 7.46, p < 0.001), fasting blood glucose (99.27 ± 17.13 vs. 97.87 ± 13.07, p = 0.007), triglycerides (149.70 ± 101.15 vs. 133.55 ± 105.17, p < 0.001), and decreased high-density lipoprotein (53.18 ± 12.82 vs. 55.61 ± 14.17, p < 0.001). As a result of logistic regression analysis on the risk of metabolic syndrome, even after adjusting for age, sex BMI, drinking, smoking, exercise, employment period, organic compound exposure. the odds ratio (OR) for the shift group was 1.300 for daytime workers (Model 1, OR: 1.491; 95% confidence interval [CI]: 1.273–1.747; Model 2, OR: 1.260; 95% CI: 1.070–1.483; Model 3, OR: 1.309, 95% CI: 1.081–1.585; Model 4, OR: 1.300; 95% CI: 1.063–1.591).

Conclusions

Shift work in chemical plant workers increased the risk of metabolic syndrome, even after adjusting for general factors. To analyze the occupational cause and risk control, it is necessary to analyze the hazardous substances the workers were exposed to and their working environment. Additionally, a large-scale prospective analysis including general factors not analyzed in this study, such as eating habits, is required.

일개 화학공장 근로자에서의 교대근무와 대사증후군의 관계에 관한 연구
목적
이 연구는 화학공장에 근무하는 근로자를 대상으로 교대 근무 그룹과 주간 근무 그룹에서 대사 증후군의 유병율과 교대 근무와 대사 증후군 사이의 연관성을 확인하는 것을 목표로 했다.
방법
2019년 2월 실시한 건강검진 자료를 바탕으로 대한민국의 한 화학공장에 근무하는 근로자 3,794 명을 대상으로 선정하였다. 신장, 체중, 허리둘레, 혈압을 신체계측으로 측정하고 혈당, 콜레스테롤의 혈액학적 검사와 나이, 성별, 흡연, 음주, 운동, 근무기간, 유기화합물 노출 여부의 데이터를 수집하여 대사증후군을 진단하였다. 연구대상자의 일반적 특성, 건강 생활 행태 관련 특성에 따른 대사증후군 위험도를 검정하기 위해서 각각의 인자에 대해 단순 로지스틱 회귀 분석을 시행하였다. 이어서, 둘사이의 관계를 알기 위해 나이, 성별, BMI, 운동, 흡연, 음주, 유기화합물 노출여부, 근무기간을 조정하여 다중 로지스틱 회귀 분석을 실시하였다.
결과
전체 연구 대상 그룹에서 대사증후군의 유병률은 23.4% 로 나타났으며, 교대근무자는 대사증후군 유병률과 구성요소 – 허리둘레 (84.77±8.64 vs 83.41±9.42, p<0.001), 수축기 혈압 (129.89±9.47 vs 127.57±9.47, p<0.001), 이완기 혈압 (81.22±7.59 vs 79.34±7.46, p<0.001), 공복혈당 (99.27±17.13 vs 97.87±13.07, p=0.007), 중성지방 (149.70±101.15 vs 133.55±105.17, p<0.001), 고밀도 지단백 저하 (53.18±12.82 vs 55.61±14.17, p<0.001) 가 주간근로자에 비해 높았다. 대사증후군 위험도에 대한 로지스틱 회귀분석을 실시한 결과 나이, 성별, BMI, 흡연, 운동, 음주, 근무기간, 유기화합물 노출이 보정된 후에도 교대근무군의 교차비는 주간근로자에 대하여 1.300 으로 나타났다. (Model 1, OR: 1.491, 95% confidence interval [CI]: 1.273-1.747; Model 2, OR : 1.260, 95% CI : 1.070-1.483 ; Model 3, OR: 1.309, 95% CI: 1.081-1.585 ; Model 4, OR : 1.300, 95% CI: 1.063-1.591).
결론
화학 공장 근로자에서 교대근무는 일반적요인을 보정한 후에도 대사증후군의 위험도를 증가시켰다. 이에 대한 직업적 원인분석과 위험통제를 위해 노출되는 유해물질과 작업환경에 대한 추가 분석이 필요하며, 식습관과 같은 이번연구에서 분석하지못한 일반적 원인을 포함한 대규모 전향적 추가 분석이 필요하다.

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Research Articles
A study of job stress, suicidal ideation and suicide attempts in display manufacturing workers: a cross-sectional study
Seung-hwan Ahn, Yong-Jin Lee, Eun-Chul Jang, Soon-Chan Kwon, Young-Sun Min, Seung-Hoon Ryu
Ann Occup Environ Med 2020;32:e16.   Published online June 2, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e16
AbstractAbstract PDFPubReaderePub
Background

This study aimed to investigate the association between job stress and suicide ideation/attempts among display manufacturing workers.

Methods

Data were collected from 836 workers in a display manufacturing company who participated in health screenings from May 22 to June 16, 2017. The data included general characteristics, night work, job tenure, previous physician-diagnosed chronic diseases, suicidal ideation/suicide attempts, and job stress. We investigated suicidal ideation/suicide attempts that covered the past year by using a self-reported questionnaire. Job stress was measured using the 43-item Korean Occupational Stress Scale. Multiple logistic regression analysis was used to investigate the association between job stress and suicidal ideation/suicide attempts. The mediator effect of depression on suicidal ideation/suicide attempts was tested using a series of logistic regression by applying Baron and Kenny's mediation method.

Results

In the model adjusting for variables (e.g., age, body mass index, smoking, alcohol consumption, regular exercise, shift work, job tenure, chronic disease and depression), physical environment (OR: 3.60, 95% CI: 1.08–12.02), lack of reward (OR: 5.31, 95% CI: 1.54–18.34), and occupation climate (OR: 7.36, 95% CI: 2.28–23.72) were correlated with suicidal ideation/suicide attempts in women. However, all subscales of job stress were not significantly correlated with suicidal ideation/suicide attempts in men. In mediation analysis, job instability and occupational climate were correlated with suicidal ideation/suicide attempts and were mediated by depression in men workers.

Conclusions

In women workers, the experiences of suicidal ideation/suicide attempts were significantly correlated with the physical environment, lack of reward, and occupational climate that were subscales of job stress. In men workers, depression rather than job stress was correlated with experiences of suicidal ideation/suicide attempts.


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    Frontiers in Public Health.2023;[Epub]     CrossRef
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Relationship of spouses' weekly working hours and sleep problems in Korean wage workers: the 5th Korean working conditions survey
Chan Park, Eun-Chul Jang, Yong-Jin Lee, Soon-Chan Kwon, Young-Sun Min, Seong-Ryoul Chai
Ann Occup Environ Med 2020;32:e14.   Published online June 1, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e14
AbstractAbstract PDFPubReaderePub
Background

Sleep disorders are common and serious problems for mental health. This study investigated the relationship between spouses' weekly working hours (SWWH) and sleep problems by using the data from the 5th Korean Working Conditions Survey.

Methods

Data from 14,921 wage workers were used in the 5th Korean Working Conditions Survey. General and occupational characteristics, sleep problems are included in the questionnaire. Multivariate logistic regression analysis was used after adjustment for general and occupational characteristics to find the relationship between SWWH and sleep problems.

Results

Compared to those whose spouses worked less than 40 hours per week, risk of trouble falling asleep, waking up repeatedly while sleeping, and waking up with a feeling of exhaustion and fatigue was significantly higher as SWWH increase among those whose spouses worked 53 or more hours per week (odds ratio [OR]: 1.40, 95% confidence interval [CI]: 1.16–1.70; OR: 1.50, 95% CI: 1.23–1.82; OR: 1.51, 95% CI: 1.24–1.83).

Conclusions

SWWH were related to sleep problems among Korean wage workers.


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Relationship between job stress and functional dyspepsia in display manufacturing sector workers: a cross-sectional study
Younghyeon Nam, Soon-Chan Kwon, Yong-Jin Lee, Eun-Chul Jang, Seung-hwan Ahn
Ann Occup Environ Med 2018;30:62.   Published online October 19, 2018
DOI: https://doi.org/10.1186/s40557-018-0274-4
AbstractAbstract PDFPubReaderePub
Background

Job stress has been reported as a risk factor of psychological changes, which have been shown to be related to gastrointestinal diseases and symptoms such as functional dyspepsia. However, few studies have assessed the relationship between job stress and functional dyspepsia. Therefore, we investigated the relationship between job stress and functional dyspepsia in South Korea.

Methods

This study was conducted between May 23 and July 6, 2016 and included 901 workers in the display manufacturing sector. Subjects completed self-reported questionnaires, regarding Korean Occupational Stress Scale (KOSS), functional dyspepsia, Insomnia Severity Index-K, and health-related behaviors and job characteristics. Subjects were divided into functional dyspepsia-positive and -negative groups based on the Rome III criteria. The KOSS high-risk group was defined as subjects with KOSS score above the 75 percentile of KOSS reference value. Multiple logistic regression analysis was performed to investigate the association between job stress and functional dyspepsia.

Results

In women, the risk of functional dyspepsia was significantly higher in the high-risk groups of the following KOSS subcategories in unadjusted model: job demand (OR 3.282, 95% CI 1.181–9.126), and occupational climate (OR 2.665, 95% CI 1.041–6.823). Even in adjusted model, the risk was significantly higher in the high-risk groups of the following KOSS subcategories: job demand (OR 3.123, 95% CI 1.036–9.416) and occupational climate (OR 3.304, 95% CI 1.198–9.115). In men, the risk of functional dyspepsia was not significant in all KOSS subcategories.

Conclusions

This study showed that job demand and occupational climates were associated with functional dyspepsia in female display manufacturing sector workers. Therefore, both clinical and mental health approaches should be used in the management of functional dyspepsia in women.


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The associations between work-related factors and temporomandibular disorders among female full-time employees: findings from the Fourth Korea National Health and Nutrition Examination Survey IV (2007–2009)
Wook Han, Soon-Chan Kwon, Yong-Jin Lee, Chan Park, Eun-Chul Jang
Ann Occup Environ Med 2018;30:42.   Published online June 20, 2018
DOI: https://doi.org/10.1186/s40557-018-0253-9
AbstractAbstract PDFPubReaderePub
Background

The aim of this study was to investigate the association between work-related factors and temporomandibular disorders (TMD) among female full-time employees using representative data from a national population-based survey.

Methods

Data from the Fourth Korea National Health and Nutrition Examination Survey IV (2007–2009) were used to analyze 1,612 women. Complex samples logistic regression was applied for adjusting for general characteristics and work-related factors to examine the association between work-related factors and TMD.

Results

The prevalence of TMD was 12.8% in this study population. With respect to age, educational status, marital status, problem drinking, exercise, and stress, there were statistically significant differences in the prevalence of TMD. In logistic regression analyses on complex samples, based on 40 h or less per week, odds ratios (ORs) for respondents who worked 40–48 working hours, 49–60 working hours, and more than 60 h were 1.16 (95% confidence interval (CI) 0.69–1.94), 1.41 (95% CI 0.79–2.54), and 2.43 (95% CI 1.29–4.59), after adjusting for general characteristics, working schedule, employment status, and occupation.

Conclusions

This study found that long working hours were significantly associated with TMD in Korean female full-time employees.


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Short Communication
Environmental health centers for asbestos and their health impact surveys and activities
Dong-Mug Kang, Jong-Eun Kim, Yong-Jin Lee, Hyun-Hee Lee, Chang-yeol Lee, Seong-Jae Moon, Min-Sung Kang
Ann Occup Environ Med 2016;28:68.   Published online December 1, 2016
DOI: https://doi.org/10.1186/s40557-016-0154-8
AbstractAbstract PDFPubReaderePub

In 2009, Korea banned the import, transport, and use of asbestos, and the Asbestos Injury Relief Act (AIRA) was promulgated in 2011. Two environmental health centers for asbestos (EHCA), including Pusan National University Yangsan Hospital (PNUYH) and SoonChunHyang University Cheonan Hospital (SCHUCH), were adapted to find environmental asbestos-related diseases (ARDs) and to support the purposes of AIRA. EHCA conducted a health impact survey (HIS) on persons who resided or reside near asbestos factories or mines. A total of 13,433 persons have taken screening examinations in PNUYH EHCA, and 623 persons (4.6%) have had secondary examinations. Of the 21,014 persons who had screening examinations in SCHUCH EHCA, 2490 persons (11.8%) had secondary examinations. Some of those who tested positive for ARDs through HISs filed applications for the asbestos victims’ medical pocketbook (AVMP). Approximately 116 and 612 persons received AVMPs as a result of PNUYH and SCHUCH examinees, respectively. EHCAs have conducted HISs, public relations, and education for asbestos victims, ordinary citizens, and physicians. As HISs are based on voluntary participation, they does not monitor high-risk groups. Active surveillance focusing on high-risk groups has been blocked by the personal information protection act. Although important work has been performed in finding environmental asbestos victims and increasing public awareness on asbestos, it is necessary to improve the current system and registration.


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    Environmental Health.2024;[Epub]     CrossRef
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    Min-Sung Kang, Woo-Ri Chae, Yong-Jin Lee, Kyong Whan Moon
    Toxics.2023; 12(1): 20.     CrossRef
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    Da-An Huh, Woo-Ri Chae, Yun-Hee Choi, Min-Sung Kang, Yong-Jin Lee, Kyong-Whan Moon
    International Journal of Environmental Research and Public Health.2022; 19(23): 15934.     CrossRef
  • Occupational and environmental asbestos exposure and the risk of lung cancer in Korea: A case-control study in South Chungcheong Province of Korea
    Da-An Huh, Min-Sung Kang, Jiyun Lee, Ji Yoon Choi, Kyong Whan Moon, Yong-Jin Lee, Flavio Manoel Rodrigues Da Silva Júnior
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    Dongmug Kang, Seung Ho Lee, Yoon Ji Kim, Tae Kyoung Kim, Ju Young Kim, Youngki Kim
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    Dongmug Kang, Yu-Young Kim, Minseung Shin, Min-Su Lee, Hee-Joo Bae, Se-Yeong Kim, Young-Ki Kim
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Research Articles
Night shift work and inflammatory markers in male workers aged 20–39 in a display manufacturing company
Seong-Woo Kim, Eun-Chul Jang, Soon-Chan Kwon, Wook Han, Min-Sung Kang, Young-Hyeon Nam, Yong-Jin Lee
Ann Occup Environ Med 2016;28:48.   Published online September 20, 2016
DOI: https://doi.org/10.1186/s40557-016-0135-y
AbstractAbstract PDFPubReaderePub
Background

This study aimed to determine the association between shift work and inflammatory markers, which are independent risk factors of cardiovascular diseases, in male manual workers at a display manufacturing company.

Methods

This study was conducted between June 1 and July 31, 2015 on 244 male manual workers aged 20–39 years old at a display manufacturing company and investigated age, marital status, education level, alcohol consumption habit, smoking habit, regular exercise habit, sleep duration, sleep debt, sleep insufficiency, past medical history, current and past shift work experience, duration of shift work, and weekly work hours through face-to-face interviews using structured questionnaires and performed blood tests. Study participants were divided into daytime, former shift, and current shift workers based on the work schedule. Chi-square tests and one-way analyses of variance were performed to compare inflammatory markers and cardiovascular disease risk factors, and analyses of covariance were conducted after adjusting for variables potentially affecting inflammatory markers.

Results

High-sensitivity C-reactive protein (hs-CRP; mean ± standard deviation) levels in daytime, former shift, and current shift workers were 0.65 ± 0.43, 0.75 ± 0.43, and 0.86 ± 0.72 mg/L, respectively (p = 0.029). The leukocyte count (mean ± standard deviation) was 5,556 ± 1,123, 6,210 ± 1,366, and 6,530 ± 1,216 cells/μL, respectively (p < 0.001). Both hs-CRP level and leukocyte count were significantly higher in current shift workers than in daytime workers, and leukocyte count was higher in former shift workers than in daytime workers. After adjusting for variables potentially affecting inflammatory markers, hs-CRP levels (adjusted mean ± standard deviation) in daytime and current shift workers were 0.59 ± 0.06 and 0.92 ± 0.07 mg/L, respectively (p = 0.002). The leukocyte count (adjusted mean ± standard deviation) was 5,557 ± 124 and 6,498 ± 144 cells/μL, respectively (p < 0.001).

Conclusions

A significant association between shift work and increases in inflammatory markers was confirmed. Because chronic low-grade inflammation plays an important role in the development of cardiovascular diseases, regular follow-up of inflammatory markers as a marker of cardiovascular diseases in shift workers may serve as an early indicator in predicting the effects of shift work on health.


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Employment and occupation effects on late-life depressive symptoms among older Koreans: a cross-sectional population survey
Hyun Park, Young Hwangbo, Yong-Jin Lee, Eun-Chul Jang, Wook Han
Ann Occup Environ Med 2016;28:22.   Published online May 14, 2016
DOI: https://doi.org/10.1186/s40557-016-0107-2
AbstractAbstract PDFPubReaderePub
Background

The present study investigated the prevalence of depressive symptoms in older Koreans and identified associations between depressive symptoms and occupational factors.

Methods

Data from the Korean National Health and Nutrition Examination Survey V (2010–2012) were used to analyze 7320 participants aged 55 years or older. Complex sample logistic regression analysis was performed after adjusting general characteristics to determine associations between depressive symptoms and occupational factors.

Results

Among older Korean men, the prevalence of depressive symptoms in the employed and the non-employed groups were 9.9 % and 13.7 %, respectively. Employment status was significantly associated with depressive symptoms after adjusting for general factors (OR: 0.69, 95 % CI: 0.49–0.97). Among older Korean women, the prevalence of depressive symptoms in the employed and the non-employed groups were 17.4 % and 20.3 %, respectively, but employment status was not significantly associated with depressive symptoms. Second skill level occupational groups (clerks, plant and machine operators) in particular showed significantly lower prevalence of depressive symptoms than the non-employed group of men (9.3 % vs 13.7 %). By occupation type, the odds ratios were 0.31 (95 % CI: 0.10–0.97, clerks) and 0.47 (95 % CI: 0.23–0.86, plant and machine operators) adjusting for general factors.

Conclusions

The employed group showed lower late-life depressive symptom prevalence than the non-employed group among older Korean men. In addition some second skill level occupations (clerks, plant and machine operators) were significantly associated with a lower risk of depressive symptoms after adjusting for general factors in older Korean men.


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Association between long working hours and serum gamma-glutamyltransferase levels in female workers: data from the fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Seung-Gwon Park, Yong-Jin Lee, Jung-Oh Ham, Eun-Chul Jang, Seong-Woo Kim, Hyun Park
Ann Occup Environ Med 2014;26:40.   Published online December 1, 2014
DOI: https://doi.org/10.1186/s40557-014-0040-1
AbstractAbstract PDFPubReaderePub
Objectives

The present study investigated the association between long working hours and serum gamma-glutamyltransferase (GGT) levels, a factor influencing the incidence of cardiovascular disease.

Methods

Data from the fifth Korean National Health and Nutrition Examination Survey (2010–2011) were used to analyze 1,809 women. Subjects were divided into three groups based on the number of weekly working hours: ≤29, 30–51, and ≥52 hours per week. Complex samples logistic regression was performed after adjusting for general and occupational factors to determine the association between long working hours and high serum GGT levels.

Results

The prevalence of high serum GGT levels in groups with ≤29, 30–51, and ≥52 working hours per week was 22.0%, 16.9%, and 26.6%, respectively. Even after adjusting for general and occupational factors, those working 30–51 hours per week had the lowest prevalence of high serum GGT levels. Compared to those working 30–51 hours per week, the odds ratios (OR) of having high serum GGT levels in the groups with ≥52 and ≤29 working hours per week were 1.56 (95% confidence interval [CI], 1.10–2.23) and 1.53 (95% CI, 1.05–2.24), respectively.

Conclusions

Long working hours were significantly associated with high serum GGT levels in Korean women.


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