A Suspicious Case of Dimethylformamide Induced Fulminant Hepatitis in Synthetic Leather Workers

Soo Keun Kim; Soo Jin Lee; Kyou Chull Chung

doi:10.35371/kjoem.1995.7.1.186

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Case Report A Suspicious Case of Dimethylformamide Induced Fulminant Hepatitis in Synthetic Leather Workers: Soo Keun Kim, Soo Jin Lee, Kyou Chull Chung; DOI: https://doi.org/10.35371/kjoem.1995.7.1.186
Published online: February 28, 1995

¹Department of Preventive medicine, College of Medicine, Han Yang University, Korea.

²Center for Occupational Health, Hanyang University Hospital, Korea.

³Institute for Industrial Health, Korean Industrial Health Association, Korea.

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Abstract

A man who worked in the synthetic leather manufacturing plant for 3 months died at November 3. Author review the medical record, the death certificate, and interviewed his wife and the doctor who treated him. His major job was DMF handling. At the working place, he felt severe health problem, and admitted to the hospital via emergency clinic. He complained severe abdominal pain and showed jaundice and ascites, He suffered hepatic coma and respiratory insufficiency from fulminant hepatitis from 19th days after admission. Drug abuse, hepatitis (A, B, C), and alcoholic hepatitis were rule out with his history and serological study data, As a result, author couldn't find any cause of death, but fuIminant hepatitis from DMF toxicity.

Keywords: Toxic hapatitis;Dimethylformamide

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