Annals of Occupational and Environmental Medicine

Original Article

Association of weight and dietary habits with high blood mercury levels in Korean adolescents: data from the KoNEHS cycle 4, 2018-2020: Ji Hoon Kim, Minju Jung, Jaewon Mun, Dong-Jae Seo, Jong-Han Leem, Shin-Goo Park, Dong-Wook Lee, Hyung Doo Kim, Hwan-Cheol Kim; Ann Occup Environ Med 2025;37:e5. Published online February 21, 2025; DOI: https://doi.org/10.35371/aoem.2025.37.e5

Abstract Abstract in Korean PDF Supplementary Material

Background
Humans are exposed to mercury primarily in its highly toxic form, methyl mercury, which is known to have adverse effects on various organs and systems. The negative impact of mercury exposure on the growth, development, and mental health of children, from infancy to adolescence, is well-documented. However, there are no internationally standardized safe limits for mercury exposure. This study investigated the impact of dietary habits and higher body mass index (BMI) on blood mercury levels in adolescents.
Methods
This study analyzed the data from the 4th Korean National Environmental Health Survey (KoNEHS) 2018–2020. The focus was on 825 middle and high school students aged 13–18 years, whose blood mercury levels were measured. A survey on dietary and lifestyle habits was also conducted. Blood mercury levels were categorized by geometric median values, and associations with overweight status and seafood consumption were examined using a generalized linear model.
Results
The geometric mean blood mercury level for the entire sample was 1.37 μg/L, with levels of 1.31 μg/L in normal-weight individuals and 1.43 μg/L in overweight individuals, showing a statistically significant difference between the two groups. After adjusting for other variables, blood mercury levels were significantly associated with overweight status (estimate: 0.084; p = 0.018; 95% confidence interval [CI]: 0.015–0.153), consumption of large fish and tuna more than once a week (estimate: 0.18; p = 0.001; 95% CI: 0.077–0.284), and consumption of fish once a week or more (estimate: 0.147; p = 0.004; 95% CI: 0.043–0.250).
Conclusions
In adolescents, a higher BMI and an increased consumption of large fish, tuna, and fish were associated with higher blood mercury levels. Notably, a stronger association was found between large fish consumption and blood mercury levels in the overweight group. These findings suggest the need to moderate seafood consumption and establish more proactive mercury exposure standards for adolescents.

한국 청소년에서 체중 및 식습관과 높은 혈중 수은 농도의 연관: KNHANES 제4기 데이터, 2018-2020
목적
수은은 독성이 강한 형태인 메틸 수은의 상태로 인간에게 주로 노출된다. 메틸 수은은 발달 및 정신건강측면을 포함한 인체 전반에 독성 영향이 있지만 현재 국제적으로 표준화된 수은 노출 기준이 없다. 특히나 영유아나 청소년은 발달이 아직 이루어지지 않아 성인에 비해 더 수은 노출의 위험도가 높다. 본 연구에서는 청소년의 식습관이나 과체중 여부가 혈중 수은 노출에 미치는 영향을 조사하였다.
방법
본 연구는 국립환경과학원에서 발간하는 제4기 국민환경보건 기초조사(2018-2020)를 활용하였다. 제4기 대상 중 혈중 수은 농도가 측정 된 13-18세의 중, 고등학생 825명을 대상으로 하였고 식습관이나 생활 습관에 대한 개인 설문을 활용하였다. 혈중 수은 농도 중위 값을 기준으로 구분하여 과체중 여부를 구분하여 각종 해산물 식습관과 혈중 수은 농도와의 연관성을 로지스틱 회귀 모델을 사용하여 조사하였고, 이 후 전체 연구 대상자를 대상으로 연관성을 조사하였다.
결과
전체 표본의 기하평균 혈중 수은 농도는 1.37 µg/L로, 정상체중 군은 1.31 µg/L, 과체중 군은 1.43 µg/L로 나타났으며, 두 군 간에 통계적으로 유의미한 차이가 있었다. 다른 변수들을 조정한 후, 혈중 수은 농도는 과체중 상태(추정값: 0.084; p-value: 0.018; 95% 신뢰구간[CI]: 0.015-0.153), 주 1회 이상 대형어류와 참치 섭취(추정값: 0.18; p-value: 0.001; 95% CI: 0.077-0.284), 주 1회 이상 어류 섭취(추정값: 0.147; p-value: 0.004; 95% CI: 0.043-0.250)와 유의미한 관계가 있었다.
결론
청소년에서 높은 BMI와 대형어류, 참치, 어류 섭취가 높은 혈중 수은 농도와 관련이 있었다. 특히, 과체중 그룹에서는 대형어류 섭취와 혈중 수은 농도 간의 강한 연관성이 발견되었다. 이 결과는 청소년을 위한 해산물 섭취 절제와 더 적극적인 수은 노출 기준 설정이 필요함을 시사한다.

Citations

Citations to this article as recorded by

Association between complex exposure to cadmium and mercury and atopic dermatitis in elementary school students: analysis using data from the Korean National Environmental Health Survey (KoNEHS) Cycle 4
Kiook Baek
Central European Journal of Public Health.2025; 33(1): 3. CrossRef

1,365 View
146 Download
1 Web of Science
1 Crossref

Original Article

Risk assessment of heavy metals in tuna from Japanese restaurants in the Republic of Korea: Seong-Jin Bae, Kyu-Sik Shin, Chulyong Park, Kiook Baek, So-Young Son, Joon Sakong; Ann Occup Environ Med 2023;35:e3. Published online February 9, 2023; DOI: https://doi.org/10.35371/aoem.2023.35.e3

Abstract Abstract in Korean PDF Supplementary Material

Background

Studies on the risk of mercury (Hg) in Korean fishery products focus primarily on total Hg levels as opposed to methylmercury (MeHg) levels. None of the few studies on MeHg in tuna investigated tuna from Japanese restaurants. Few have evaluated lead (Pb), cadmium (Cd) and arsenic (As) in tuna. Thus, this study aimed to conduct a risk assessment by evaluating heavy metal concentrations in tuna from Japanese restaurants.

Methods

Thirty-one tuna samples were collected from Japanese restaurants in the Republic of Korea. They were classified according to region and species. The concentration of heavy metals in the samples was analyzed using the Ministry of Food and Drug Safety Food Code method. The rate of exceedance of maximum residue levels (MRLs) and the risk compared to the provisional tolerable weekly intake (PTWI) set by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (%PTWI) were evaluated for risk assessment.

Results

The mean of MeHg, Pb, Cd and As concentrations were 0.56 ± 1.47 mg/kg, 33.95 ± 3.74 μg/kg, 14.25 ± 2.19 μg/kg and 1.46 ± 1.89 mg/kg, respectively. No sample exceeded the MRLs of Pb and Cd, but 9.7% of the samples exceeded the MRL of MeHg. The %PTWIs of MeHg, Pb, Cd and As were 4.2037, 0.0162, 0.0244 and 1.1627, respectively. The %PTWI of MeHg by age group and sex was highest among men aged 19–29 years (10.6494), followed by men aged 30–49 years (7.2458) and women aged 19–29 years (4.8307).

Conclusions

We found that 3 out of 31 samples exceeded the MRL of MeHg. The %PTWI of MeHg showed significant differences based on age and sex, and the value was likely to exceed a safe level depending on individuals’ eating behaviors. Therefore, improved risk management for MeHg is required.

한국의 일식집 유통 참치의 중금속(4종) 위해성평가
목적
국내 수산물의 수은에 관한 위해성 연구는 주로 메틸수은이 아닌 총 수은을 대상으로 이루어졌다. 소수의 참치의 메틸수은에 대한 연구들 중 일식점 유통 참치에 대한 연구는 없었다. 참치의 납, 카드뮴 및 비소에 대한 연구도 거의 이루어지지 않았다. 따라서 본 연구에서는 일식점 유통 참치의 중금속 농도를 평가하여 위해성평가를 실시하고자 하였다.
방법
참치는 한국의 일식집에서 총 31개의 시료가 수집되었다. 지역과 참치의 종에 따라서 분류하였다. 시료의 중금속 농도는 식품의약품안전처의 식품공전에 따라 분석했다. 위해성평가를 위해서 식품의 잔류허용기준을 초과하는 비율과 FAO/WHO합동식품첨가물 전문가위원회가 설정한 잠정주간섭취허용과 비교한 위험도(%PTWI)를 산출하였다.
결과
메틸수은, 납, 카드뮴 및 비소 농도의 기하평균은 각각 0.56 ± 1.47 mg/kg, 33.95 ± 3.74 μg/kg, 14.25 ± 2.19 μg/kg 및 1.46 ± 1.89 mg/kg이었다. 납과 카드뮴의 경우 잔류허용기준을 초과하는 시료가 없었으나 메틸수은의 경우 시료의 9.7%가 초과했다. 메틸수은, 납, 카드뮴 및 비소의 %PTWI는 4.2037, 0.0162, 0.0244 및 1.1627이었다. 메틸수은의 %PTWI는 19-29세의 남성, 30-49세의 남성, 19-29세의 여성 순으로 높았으며, 그 값은 10.6494, 7.2458, 4.8307이었다.
결론
총 31개의 시료 중 3개에서 메틸수은의 잔류허용기준을 초과하는 것으로 나타났다. 메틸수은의 %PTWI는 연령과 성별에 따라 상당한 차이를 보였고, 그리고 그 값은 섭취행태에 따라서 안전 수준을 초과할 가능성을 보였다. 따라서, 메틸수은에 대한 개선된 안전성 관리 방안이 필요할 것으로 보인다.

Citations

Citations to this article as recorded by

Metal Load of Potentially Toxic Elements in Tuna (Thunnus albacares)—Food Safety Aspects
József Lehel, Zita Papp, András Bartha, Péter Palotás, Rita Szabó, Péter Budai, Miklós Süth
Foods.2023; 12(16): 3038. CrossRef

908 View
16 Download
1 Web of Science
1 Crossref

Research Article

The association between mercury concentrations and lipid profiles in the Korean National Environmental Health Survey (KoNEHS) cycle 3: Soo Ho Sohn, Han Cheol Heo, Seongmin Jo, Chulyong Park, Joon Sakong; Ann Occup Environ Med 2020;32:e19. Published online June 22, 2020; DOI: https://doi.org/10.35371/aoem.2020.32.e19

Abstract PDF

Background

High concentrations of mercury intake from seafood are known to cause various side effects in humans, including on the nervous system. Various studies have reported the effects of mercury concentrations in humans; however, the association between dyslipidemia, a cardiovascular disease risk factor, and mercury remains controversial. Therefore, this study aimed to investigate the association between mercury accumulation and cholesterol concentrations in a Korean population.

Methods

We analyzed data of a sample of 3,228 respondents obtained from the Korean National Environmental Health Survey cycle 3, surveyed between 2015 and 2017, to determine how lipid profiles changed according to the blood mercury concentrations (BHg) and urine mercury concentrations (UHg). Multiple regression analysis was used to determine the effects of mercury concentrations among various factors affecting blood cholesterol levels.

Results

The arithmetic mean (AM) of BHg was 2.91 (2.81–3.02) μg/L, and the geometric mean (GM) was 2.71 (2.59–2.85) μg/L. The AM of UHg was 0.52 (0.48–0.56) μg/L, and the GM was 0.35 (0.33–0.38) μg/L. Lipid profiles were more related to the BHg than to the UHg. Total cholesterol (total-C), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels increased significantly as BHg increased in males, and total-C, triglyceride, and LDL-C levels increased significantly in females. Multiple regression analysis indicated that BHg were significantly associated with total-C, HDL-C, and LDL-C levels.

Conclusions

We found an association between mercury exposure and the risk of dyslipidemia; however, further studies are required to elucidate a causal association.

Citations

Citations to this article as recorded by

Re-thinking the link between exposure to mercury and blood pressure
Xue Feng Hu, Allison Loan, Hing Man Chan
Archives of Toxicology.2025; 99(2): 481. CrossRef
Do blood metals influence lipid profiles? Findings of a cross-sectional population-based survey
Sabit Cakmak, Kimberly Mitchell, Anna Lukina, Robert Dales
Environmental Research.2023; 231: 116107. CrossRef
Association of Blood Total Mercury with Dyslipidemia in a sample of U.S. Adolescents: Results from the National Health and Nutrition Examination Survey Database, 2011–2018
Chibuzor Abasilim, Victoria Persky, Mary E. Turyk
Hygiene and Environmental Health Advances.2023; 6: 100047. CrossRef
Association of Blood Mercury Level with Liver Enzymes in Korean Adults: An Analysis of 2015–2017 Korean National Environmental Health Survey
Jin-Wook Chung, Dilaram Acharya, Jitendra Kumar Singh, Joon Sakong
International Journal of Environmental Research and Public Health.2023; 20(4): 3290. CrossRef
Heavy metal-induced lipogenic gene aberration, lipid dysregulation and obesogenic effect: a review
Yang Zhou, Frank Peprah Addai, Xinshuang Zhang, Yuelin Liu, Yinfeng Wang, Feng Lin, Alex Tuffour, Jie Gu, Guangxiang Liu, Haifeng Shi
Environmental Chemistry Letters.2022; 20(3): 1611. CrossRef
Mercury may reduce the protective effect of sea fish consumption on serum triglycerides levels in Chinese adults: Evidence from China National Human Biomonitoring
Bing Wu, Yingli Qu, Yifu Lu, Saisai Ji, Liang Ding, Zheng Li, Miao Zhang, Heng Gu, Qi Sun, Bo Ying, Feng Zhao, Xulin Zheng, Yidan Qiu, Zheng Zhang, Ying Zhu, Zhaojin Cao, Yuebin Lv, Xiaoming Shi
Environmental Pollution.2022; 311: 119904. CrossRef
Misuse of Cardiac Lipid upon Exposure to Toxic Trace Elements—A Focused Review
Kaviyarasi Renu, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Sathishkumar Vinayagam, Vishnu Priya Veeraraghavan, Balachandar Vellingiri, Alex George, Ricardo Lagoa, Kamaraj Sattu, Abhijit Dey, Abilash Valsala Gopalakrishnan
Molecules.2022; 27(17): 5657. CrossRef
The effects of chemical mixtures on lipid profiles in the Korean adult population: threshold and molecular mechanisms for dyslipidemia involved
Hai Duc Nguyen, Hojin Oh, Min-Sun Kim
Environmental Science and Pollution Research.2022; 29(26): 39182. CrossRef
Association between Heavy Metal Exposure and Dyslipidemia among Korean Adults: From the Korean National Environmental Health Survey, 2015–2017
Do-won Kim, Jeongwon Ock, Kyong-Whan Moon, Choong-Hee Park
International Journal of Environmental Research and Public Health.2022; 19(6): 3181. CrossRef

789 View
3 Download
7 Web of Science
9 Crossref

Research Article

Mercury concentration in shark meat from traditional markets of Gyeongsangbuk-do, South Korea: Han Cheol Heo, Yeon Hee Lim, Young Seok Byun, Joon Sakong; Ann Occup Environ Med 2020;32:e3. Published online January 2, 2020; DOI: https://doi.org/10.35371/aoem.2020.32.e3

Abstract PDF

Background

Although unusually high levels of blood mercury have been reported in the North Gyeongsang Province (Gyeongsangbuk-do), mercury contents from shark meat distributed in this region have not been assessed yet. Thus, this study aims to identify the hazard by evaluating the mercury contents of the shark meat sold in the traditional market of Gyeongsangbuk-do.

Methods

The shark meat in the form of muscle meat was obtained from 15 traditional markets of Gyeongsangbuk-do in the summer and winter of 2013. Out of 105 samples in total, 49 were collected in the summer and 56 in the winter. The total mercury concentration was measured by the combustion-gold amalgamation method using an automatic mercury analyzer (Milestone DMA-80, Milestone).

Results

The average mercury concentration of shark meat was 2.29 ± 1.77 µg/g, ranging between 0.06–8.93 µg/g with a geometric mean of 1.44 µg/g, which is higher than those reported in many countries. The mercury concentration in 77 of 105 shark meat samples exceeded 1 µg/g. Mercury concentration ranged between 0.09–8.93 µg/g (geometric mean: 1.45) in the summer and 0.06–6.73 µg/g (geometric mean: 1.48) in the winter.

Conclusions

Shark meat sold in the market contained a substantial amount of mercury. This suggests that it is difficult to reduce mercury intake by simply strengthening the standard level of mercury concentration in shark meat. Therefore, it is need to communication and awareness programs with consumers about hazardous effects of mercury inherent in shark meat.

Citations

Citations to this article as recorded by

Assessment of heavy metals concentration and health risk in four species of Persian Gulf sharks in Hormozgan Province
Hassan heidarieh, Amin Gholamhosseini, Siyavash Soltanian, Marzieh Heidarieh, Mahdi Banaee, Nima Shiry
Journal of Trace Elements in Medicine and Biology.2025; 87: 127581. CrossRef
Monitoring of Cadmium, Lead, and Mercury Levels in Seafood Products: A Ten-Year Analysis
Luisa Garofalo, Marcello Sala, Claudia Focardi, Patrizio Pasqualetti, Daniela Delfino, Francesca D’Onofrio, Barbara Droghei, Francesca Pasquali, Valentina Nicolini, Flavia Silvia Galli, Paola Scaramozzino, Alessandro Ubaldi, Katia Russo, Bruno Neri
Foods.2025; 14(3): 451. CrossRef
Metallic Makos: Metal and Metalloid Levels and Human Health Risks Arising from the Consumption of Shortfin Makos (Isurus oxyrinchus) from Southeastern Brazil
Júlia Vianna de Pinho, Isabel Quental Willmer, Amanda Pontes Lopes, Regina Fonsêca, Tatiana Dillenburg Saint’Pierre, Patricia Charvet, Acácio Ribeiro Gomes Tomas, Rachel Ann Hauser-Davis
Biological Trace Element Research.2025;[Epub] CrossRef
Association of Blood Mercury Level with Liver Enzymes in Korean Adults: An Analysis of 2015–2017 Korean National Environmental Health Survey
Jin-Wook Chung, Dilaram Acharya, Jitendra Kumar Singh, Joon Sakong
International Journal of Environmental Research and Public Health.2023; 20(4): 3290. CrossRef
Increase of blood mercury level with shark meat consumption: A repeated-measures study before and after Chuseok, Korean holiday
Kiook Baek, Chulyong Park, Joon Sakong
Chemosphere.2023; 344: 140317. CrossRef
Mercury cycling in Australian estuaries and near shore coastal ecosystems: Triggers for management
William Maher, Frank Krikowa, Michael Ellwood, Detlev Helmig, Ruoyu Sun
Elementa: Science of the Anthropocene.2020;[Epub] CrossRef

789 View
5 Download
5 Web of Science
6 Crossref

Research Article

The effects of exposure to lead, cadmium and mercury on follicle-stimulating hormone levels in men and postmenopausal women: data from the Second Korean National Environmental Health Survey (2012–2014): Tae-Woo Lee, Dae Hwan Kim, Ji Young Ryu; Ann Occup Environ Med 2019;31:e21. Published online August 28, 2019; DOI: https://doi.org/10.35371/aoem.2019.31.e21

Abstract PDF

Background

Follicle-stimulating hormone (FSH), a gonadotropin secreted by the pituitary gland, is a representative secondary sex hormone and an important indicator of reproductive function. The effects of heavy metals such as lead, cadmium, and mercury on humans have been studied, but reports on their effects on sex hormone levels are lacking. Therefore, we investigated the relationship between heavy metal exposure and FSH levels in Korean men and postmenopausal women.

Methods

A total of 4,689 adults (2,763 men and 1,926 postmenopausal women aged 50 years or over) who participated in the Second Korean National Environmental Health Survey (2012–2014) were included. We compared differences in serum FSH levels by demographic characteristics using the t-test and analysis of variance. Multiple linear regression analysis was used to determine the relationship between the blood levels of lead and mercury and the urine cadmium level, and serum FSH levels.

Results

On multiple linear regression analysis, lead exposure was positively associated with serum FSH concentrations in postmenopausal women (β = 2.929, p = 0.019). However, we found no significant association between serum FSH concentration and blood lead and mercury levels, or urine cadmium level, in men.

Conclusions

This study suggests that lead exposure can affect the FSH level in postmenopausal women. Further studies are needed to evaluate the effects of low-dose long-term exposure to heavy metals on sex hormones.

Citations

Citations to this article as recorded by

ADAPTIVE REARRANGEMENTS OF STRUCTURAL COMPONENTS IN THE ADULT RATS’ ADENOHYPOPHYSIS AFTER LONG-TERM EXPOSURE TO HEAVY METAL SALTS
N. B. Hryntsova, A. M. Romaniuk, V. I. Bumeister, K. O. Sikora
World of Medicine and Biology.2024; 20(87): 192. CrossRef
Hormonal profile changes under the influence of environmental factors in children residing in the Aral environmental disaster region
Valerii O. Erkudov, Kenzhabek Umar ugli Rozumbetov, Azat T. Matchanov, Andrey P. Pugovkin, Symbat N. Nisanova, Madina A. Kalmuratova, Andrey V. Kochubeev, Sergey S. Rogozin
Pediatrician (St. Petersburg).2024; 14(5): 51. CrossRef
Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN)
Xin Wang, Ning Ding, Siobán D. Harlow, John F. Randolph, Bhramar Mukherjee, Ellen B. Gold, Sung Kyun Park
Environmental Pollution.2023; 317: 120740. CrossRef
Association of Blood Mercury Level with Liver Enzymes in Korean Adults: An Analysis of 2015–2017 Korean National Environmental Health Survey
Jin-Wook Chung, Dilaram Acharya, Jitendra Kumar Singh, Joon Sakong
International Journal of Environmental Research and Public Health.2023; 20(4): 3290. CrossRef
Exposure to endocrine-disrupting metals and serum estrogen levels among US women
Anna Corry Gerald, Srividya Ganapathy, Jianmin Zhu, Yudan Wei
Reproductive Toxicology.2023; 118: 108392. CrossRef
A cross-sectional study of the association between heavy metals and pan-cancers associated with sex hormones in NHANES 1999–2018
Hai-ming Cao, Ya-zhu Yang, Bao-yi Huang, Yunzhe Zhang, Yu Wu, Zi Wan, Lin Ma
Environmental Science and Pollution Research.2023; 30(21): 61005. CrossRef
Exposure to mixed chemicals elevated triiodothyronine (T3) and follicle-stimulating hormone (FSH) levels: epidemiology and in silico toxicogenomic involvement
Hai Duc Nguyen
Environmental Science and Pollution Research.2023; 30(38): 88803. CrossRef
The Association Between Heavy Metals Exposure and Sex Hormones: a Systematic Review on Current Evidence
Yasaman Rami, Karim Ebrahimpour, Mahboobeh Maghami, Bahareh Shoshtari-Yeganeh, Roya Kelishadi
Biological Trace Element Research.2022; 200(8): 3491. CrossRef
Follicle-stimulating hormone and blood lead levels with bone mineral density and the risk of fractures in pre- and postmenopausal women
Huixin Tong, Bo Su, Zhize Liu, Yongjie Chen
Frontiers in Endocrinology.2022;[Epub] CrossRef
Adaptive morphofunctional rearrangements in the adult rats adenohypophysis after long-term exposure of heavy metal salts
Hryntsova Nataliia, Hodorova Ingrid, Romanyuk Anatoly, Kravets Alexander, Rybarova Silvia, Lovasova Kvetuse, Mihalik Josef, Pavliuk-Karachevtseva Andriana, Vecanova Janka, Kolesar Dalibor, Bolekova Andriana, Flesarova Slavka
Acta Medica Martiniana.2022; 22(2): 70. CrossRef
Association between blood cadmium and vitamin D levels in the Yangtze Plain of China in the context of rapid urbanization
Chi Chen, Hao-Jie Zhang, Hua-Ling Zhai, Yi Chen, Bing Han, Qin Li, Fang-Zhen Xia, Ning-Jian Wang, Ying-Li Lu
Chinese Medical Journal.2021; 134(1): 53. CrossRef
Indoor particulate matter and blood heavy metals in housewives: A repeated measured study
Dong-Wook Lee, Jongmin Oh, Shinhee Ye, Youngrin Kwag, Wonho Yang, Yangho Kim, Eunhee Ha
Environmental Research.2021; 197: 111013. CrossRef
Prenatal blood levels of some toxic metals and the risk of spontaneous abortion
Mohsen Vigeh, Masud Yunesian, Takehise Matsukawa, Mansour Shamsipour, Maryam Zare Jeddi, Noushin Rastkari, Mohammad Sadegh Hassanvand, Mamak Shariat, Homa Kashani, Reihaneh Pirjani, Mohammad Effatpanah, Mahboobeh Shirazi, Ghazal Shariatpanahi, Katsumi Oht
Journal of Environmental Health Science and Engineering.2021; 19(1): 357. CrossRef
Independent and combined associations of urinary heavy metals exposure and serum sex hormones among adults in NHANES 2013–2016
Chengzhe Tao, Zhi Li, Yun Fan, Xiuzhu Li, Hong Qian, Hao Yu, Qiaoqiao Xu, Chuncheng Lu
Environmental Pollution.2021; 281: 117097. CrossRef
Effects of Cadmium, Lead, and Mercury on the Structure and Function of Reproductive Organs
Peter Massányi, Martin Massányi, Roberto Madeddu, Robert Stawarz, Norbert Lukáč
Toxics.2020; 8(4): 94. CrossRef

716 View
4 Download
14 Web of Science
15 Crossref

Research Article

A study of relationship between blood mercury concentration and hypertension in residents living in old mine fields and related factors: Jeong Woo Kim, Byoung Gwon Kim, Jeong Woo Park, Jong Woo Yi, Jung Il Kim, Young Seoub Hong; Ann Occup Environ Med 2019;31:e6. Published online May 30, 2019; DOI: https://doi.org/10.35371/aoem.2019.31.e6

Abstract PDF

Background

In Korea, around the abandoned metal mines, heavy metals are being accumulating in the cultivated areas. Among exposed heavy metals, mercury is known to harm for cardiovascular system known to affect blood pressure. So, we studied the relationship between blood mercury level and hypertension in residents around abandoned metal mines.

Methods

From 2008 to 2011, we surveyed 7,055 residents in provinces affected by abandoned metal mines and collected data from 6 Hospitals. We conducted a personal questionnaire interview survey with residents on the basis of household questionnaires, sex, age, household income, smoking, and drinking items. Multiple logistic regression analysis was performed to investigate the association between blood mercury level and hypertension.

Results

We compared residents with low and high groups based on blood mercury level 5.8 μg/L, and higher group was significantly higher risk of hypertension than lower group (odds ratio [OR]: 1.277; 95% confidence interval [CI]: 1.135–1.436), also in adjusted model, higher group was significantly higher risk of hypertension than lower group (OR: 1.276; 95% CI: 1.117–1.457).

Conclusions

This study showed a significant correlation between mercury and hypertension in residents around abandoned metal mines. Therefore, we should continuously monitor people who are higher than the standard value and the hypertensive patients.

Citations

Citations to this article as recorded by

Re-thinking the link between exposure to mercury and blood pressure
Xue Feng Hu, Allison Loan, Hing Man Chan
Archives of Toxicology.2025; 99(2): 481. CrossRef
Environmental exposure to metal(loid)s and hypertensive disorders of pregnancy: A systematic review
Nayra Carla de Melo, Priscilla Cristovam Sampaio e Souza, Rejane Correa Marques, José Vicente Elias Bernardi, Wanderley Rodrigues Bastos, Mônica Pereira Lima Cunha
Environmental Research.2024; 257: 119391. CrossRef
Associations of fine particulate matter and its metal constituents with blood pressure: A panel study during the seventh World Military Games
Zhaoyuan Li, Shouxin Peng, Meijin Chen, Jinhui Sun, Feifei Liu, Huaiji Wang, Hao Xiang
Environmental Research.2023; 217: 114739. CrossRef
Evaluation of the Relationship between the Exposure Level to Mixed Hazardous Heavy Metals and Health Effects Using Factor Analysis
Eunseop Kim, Sun-In Moon, Dong-Hyuk Yim, Byung-Sun Choi, Jung-Duck Park, Sang-Yong Eom, Yong-Dae Kim, Heon Kim
Journal of Environmental Health Sciences.2022; 48(4): 236. CrossRef
Blood cadmium, lead, manganese, mercury, and selenium levels in American Indian populations: The Strong Heart Study
Zheng Li, Michael Lewin, Patricia Ruiz, Anne E. Nigra, Noelle B. Henderson, Jeffery M. Jarrett, Cynthia Ward, Jianhui Zhu, Jason G. Umans, Marcia O'Leary, Ying Zhang, Angela Ragin-Wilson, Ana Navas-Acien
Environmental Research.2022; 215: 114101. CrossRef
Co-exposure to Heavy Metals and Hypertension Among Adults in South Korea
Kisok Kim, Hyejin Park
Exposure and Health.2022; 14(1): 139. CrossRef
Effects of low-level mercury exposure on brain-derived neurotrophic factor in preschool children
Can-Can Zhou, Hui Fu, Guo-Yan Zhang, Jia-Wei Ma, Min Ni, Dong-Jie Li, Fu-Ming Shen, Fang Huang
Ecotoxicology and Environmental Safety.2021; 208: 111642. CrossRef
Hydrogen sulfide and cardiovascular disease: Doubts, clues, and interpretation difficulties from studies in geothermal areas
Francesca Gorini, Elisa Bustaffa, Kyriazoula Chatzianagnostou, Fabrizio Bianchi, Cristina Vassalle
Science of The Total Environment.2020; 743: 140818. CrossRef

651 View
1 Download
6 Web of Science
8 Crossref

Research Article

The associations between blood mercury levels and shark meat intake among workers in Gyeongsangbuk-do: Gun Il Park, Young Seok Byun, Man Joong Jeon, Joon Sakong; Ann Occup Environ Med 2017;29:29. Published online June 27, 2017; DOI: https://doi.org/10.1186/s40557-017-0185-9

Abstract PDF

Background

Shark meat is used as sacrificial food in Gyeongsangbuk-do, and is a major source of dietary mercury. This study aimed to evaluate the effects of shark meat intake or the ritual of Jesa on blood mercury levels within workers living in Gyeongsangbuk-do.

Methods

This study was conducted from September 2016 to October 2016 in two cities of Gyeongsangbuk-do. To compare the differences between urban and rural areas, two workplaces each in Daegu as the urban area and Yeongcheon as the rural area were selected. General characteristics and characteristics related to shark meat consumption of the workers were acquired by personal interviews during their health examination. Blood mercury concentrations were analyzed by the gold amalgamation method using a direct mercury analyzer (DMA-80; Milestone Inc., Shelton, CT, USA).

Results

The shark consumption group had a higher blood mercury concentration than the non-consumption group. The levels of blood mercury increased with the frequency, annual intake, as well as most recent date of shark meat consumption. Moreover, the levels of mercury in blood increased according to the annual frequency of participation in Jesa (times per year) and the annual frequency of shark meat consumption during Jesa (times per year).

Conclusions

Shark meat intake and the ritual of Jesa contributed to an increase in the blood mercury levels of workers in Gyeongsangbuk-do. Therefore, it is necessary to evaluate dietary exposure, occupational as well as other factors that may influence blood mercury concentrations in workers during their health examination, particularly in regions with high mercury exposures.

Citations

Citations to this article as recorded by

Association between Blood Mercury and Seafood Consumption in Korean Adults: KoNEHS Cycle 4 (2018~2020)
Ji-Eun Oh, Tae-Hyeong Kim, Eun-Hee Lee
Biomedical Science Letters.2024; 30(1): 24. CrossRef
Association of Blood Mercury Level with Liver Enzymes in Korean Adults: An Analysis of 2015–2017 Korean National Environmental Health Survey
Jin-Wook Chung, Dilaram Acharya, Jitendra Kumar Singh, Joon Sakong
International Journal of Environmental Research and Public Health.2023; 20(4): 3290. CrossRef
Increase of blood mercury level with shark meat consumption: A repeated-measures study before and after Chuseok, Korean holiday
Kiook Baek, Chulyong Park, Joon Sakong
Chemosphere.2023; 344: 140317. CrossRef
Mercury concentration in shark meat from traditional markets of Gyeongsangbuk-do, South Korea
Han Cheol Heo, Yeon Hee Lim, Young Seok Byun, Joon Sakong
Annals of Occupational and Environmental Medicine.2020;[Epub] CrossRef
Mercury poisoning in a fisherman working on a pelagic fishing vessel due to excessive tuna consumption
Ji-Sung Ahn, Kyung Wook Kang, Won-Yang Kang, Hyeong-Min Lim, Seunghyeon Cho, Jai-Dong Moon, Won-Ju Park
Journal of Occupational Health.2018; 60(1): 89. CrossRef

538 View
0 Download
2 Web of Science
5 Crossref

Case Report

Cases of acute mercury poisoning by mercury vapor exposure during the demolition of a fluorescent lamp factory: Sang Yoon Do, Chul Gab Lee, Jae Yoon Kim, Young Hoon Moon, Min Sung Kim, In Ho Bae, Han Soo Song; Ann Occup Environ Med 2017;29:19. Published online June 20, 2017; DOI: https://doi.org/10.1186/s40557-017-0184-x

Abstract PDF

Background

In 2015, workers dismantling a fluorescent lamp factory in Korea were affected by mercury poisoning from exposure to mercury vapor.

Case presentation

Eighteen out of the 21 workers who participated in the demolition project presented with symptoms of poisoning and, of these, 10 had persistent symptoms even at 18 months after the initial exposure to mercury vapor. Early symptoms of 18 workers included a general skin rash, pruritus, myalgia, sleep disturbance, and cough and sputum production. Following alleviation of these initial symptoms, late symptoms, such as easy fatigue, insomnia, bad dreams, and anxiety disorder, began to manifest in 10 out of 18 patients. Seven workers underwent psychiatric care owing to sleep disturbance, anxiety disorder, and depression, and three workers underwent dermatologic treatment for hyperpigmentation, erythematous skin eruption, and chloracne-like skin lesions. Furthermore, three workers developed a coarse jerky movement, two had swan neck deformity of the fingers, and two received care at an anesthesiology clinic for paresthesia, such as burning sensation, cold sensation, and pain. Two workers underwent urologic treatment for dysfunction of the urologic system and impotence. However, symptomatic treatment did not result in satisfactory relief of these symptoms.

Conclusion

Awareness of the perils of mercury and prevention of mercury exposure are critical for preventing health hazards caused by mercury vapor. Chelation therapy should be performed promptly following mercury poisoning to minimize damage.

Citations

Citations to this article as recorded by

Occupational disease monitoring by the Korea Occupational Disease Surveillance Center: a narrative review
Dong-Wook Lee, Inah Kim, Jungho Hwang, Sunhaeng Choi, Tae-Won Jang, Insung Chung, Hwan-Cheol Kim, Jaebum Park, Jungwon Kim, Kyoung Sook Jeong, Youngki Kim, Eun-Soo Lee, Yangwoo Kim, Inchul Jeong, Hyunjeong Oh, Hyeoncheol Oh, Jea Chul Ha, Jeehee Min, Chul
The Ewha Medical Journal.2025;[Epub] CrossRef
Exposure to heavy metal elements may significantly increase serum prostate-specific antigen levels with overdosed dietary zinc
Yinyi Fang, Chi Chen, Xiaoyue Chen, Jukun Song, Shuangshuang Feng, Zhuang Li, Zhengnan Li, Yuliang Xiong, Qinyi Zhang, Hao Su, Heng Liu, Guohua Zhu, Bin Hu, Wei Wang, Zhangcheng Liu, Ke Jiao, Chang Zhang, Fan Zhang, Kehua Jiang, Jun He, Zhaolin Sun, Dongb
Ecotoxicology and Environmental Safety.2024; 272: 116080. CrossRef
Environmental and genetic predictors of whole blood mercury and selenium concentrations in pregnant women in a UK birth cohort
Kyle Dack, Peiyuan Huang, Caroline M Taylor, Dheeraj Rai, Sarah J Lewis
Environmental Advances.2024; 15: 100469. CrossRef
Promising the potential of β-caryophyllene on mercury chloride–induced alteration in cerebellum and spinal cord of young Wistar albino rats
Ahmad Yahyazadeh, Fatih Mehmet Gur
Naunyn-Schmiedeberg's Archives of Pharmacology.2024; 397(12): 10175. CrossRef
Metal Oxide-Based Adsorbents for Removal of Mercury in Aqueous Media: A Mini-Review
Saheed Abiola Raheem, Emmanuel Anuoluwapo Oke, Olutayo Abiodun Oluyinka, Taofik Adewale Adedosu, Haleema Omolola Adedosu
Chemistry Africa.2024; 7(9): 4683. CrossRef
Genome-Wide Association Study of Blood Mercury in European Pregnant Women and Children
Kyle Dack, Mariona Bustamante, Caroline M. Taylor, Sabrina Llop, Manuel Lozano, Paul Yousefi, Regina Gražulevičienė, Kristine Bjerve Gutzkow, Anne Lise Brantsæter, Dan Mason, Georgia Escaramís, Sarah J. Lewis
Genes.2023; 14(12): 2123. CrossRef
Investigation and monitoring of heavy metal poisoning
Nicola L Barlow, Sally M Bradberry
Journal of Clinical Pathology.2023; 76(2): 82. CrossRef
Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table
Carolina de Carvalho Machado, Ricardo Jorge Dinis-Oliveira
Journal of Clinical Medicine.2023; 12(7): 2591. CrossRef
Imprégnation mercurielle lors de travaux de dépollution d’anciens sites de production de chlore : premiers résultats
F. Testud, C. Bidaud, M.F. Arquillière, A. Guéry, M. Winnefeld
Archives des Maladies Professionnelles et de l'Environnement.2023; 84(6): 101878. CrossRef
Fluorescent lamps: A review on environmental concerns and current recycling perspectives highlighting Hg and rare earth elements
Laís Nascimento Viana, Ana Paula Senra Soares, Daniel Lima Guimarães, Wendy Johana Sandoval Rojano, Tatiana Dillenburg Saint'Pierre
Journal of Environmental Chemical Engineering.2022; 10(6): 108915. CrossRef
Mercury Exposure Among Artisanal and Small-Scale Gold Miners in Four Regions in Uganda
Mercy Wendy Wanyana, Friday E. Agaba, Deogratias K. Sekimpi, Victoria N. Mukasa, Geoffrey N. Kamese, Nkonge Douglas, John C. Ssempebwa
Journal of Health and Pollution.2020;[Epub] CrossRef
Mercury exposure in relation to sleep duration, timing, and fragmentation among adolescents in Mexico City
Erica C. Jansen, Emily C. Hector, Jaclyn M. Goodrich, Alejandra Cantoral, Martha María Téllez Rojo, Niladri Basu, Peter X.K. Song, Libni Torres Olascoaga, Karen E. Peterson
Environmental Research.2020; 191: 110216. CrossRef
Nanosized Copper Selenide for Mercury Removal from Indoor Air and Emergency Disposal of Liquid Mercury Leakage
Shengcai Wang, Jianping Yang, Zequn Yang, Wenbing Zhu, Hailong Li, Jianfei Song, Xueyi Guo
Industrial & Engineering Chemistry Research.2019; 58(47): 21881. CrossRef
Exposure routes and health effects of heavy metals on children
Muwaffak Al osman, Fei Yang, Isaac Yaw Massey
BioMetals.2019; 32(4): 563. CrossRef

867 View
2 Download
15 Web of Science
14 Crossref

Research Article

Air pollution and urinary n-acetyl-B-glucosaminidase levels in residents living near a cement plant: Min Soo Jung, Jae Yoon Kim, Hyun Seung Lee, Chul Gab Lee, Han Soo Song; Ann Occup Environ Med 2016;28:52. Published online September 29, 2016; DOI: https://doi.org/10.1186/s40557-016-0138-8

Abstract PDF

Background

To identify adverse renal effects due to air pollution derived from a cement plant in Korea. Urinary n-acetyl-B-glucosaminidase (U-NAG) levels in residents living near a cement plant were compared to those in a group who lived farther away from the plant.

Methods

From June to August 2013 and from August to November 2014, laboratory tests for U-NAG and heavy metal were conducted on 547 study participants. Based on the level of air pollution exposure, subjects were divided into the “less exposed group,” (LEG) which consisted of 66 persons who lived more than 5 km away from the cement plant, the “more exposed group from the rural area” (MEG-R), which consisted of 272 persons, and the “more exposed group from downtown area” (MEG-D), which consisted of 209 persons who lived within a 1 km radius of the cement plant. U-NAG levels >5.67 U/L were defined as “higher U-NAG” levels. We compared the prevalence of higher U-NAG levels and estimated the adjusted odds ratio (OR) by air pollution exposure using a chi-square test and multiple logistic regression analysis. Further, we estimated the interaction between air pollution exposure and heavy metal exposure in renal toxicity.

Results

The OR of higher U-NAG levels by MEG-D and MEG-R compared to LEG was 2.13 (95 % CI 0.86–4.96) and 4.79 (95 CI 1.65–10.01), respectively. Urinary cadmium (U-Cd), urinary mercury (U-Hg), age, occupation, hypertension, and diabetes had a significant association with higher U-NAG levels. However, blood lead (B-Pb), sex, and smoking were not associated with higher U-NAG. Especially, concurrent exposure to heavy metals (U-Hg or/and U-Cd) and air pollution had an additive adverse effect. In the group with both 4^th quartile heavy metal exposure (U-Cd or/and U-Hg) and air pollution exposure, the OR in MEG-R and MEG-D was 6.49 (95 % 1.42–29.65) and 8.12 (95 % CI 1.74–37.92), respectively, after adjustment for age, occupation, hypertension, diabetes.

Conclusions

U-NAG levels seem to be affected by air pollution exposure as well as age, hypertension, diabetes, and even low levels of cadmium and low levels of mercury. Moreover, concurrent exposure to heavy metals and air pollution can have additive cytotoxic renal effects.

Citations

Citations to this article as recorded by

Mechanisms of microbial resistance against cadmium – a review
Monu Sharma, Sonu Sharma, Paavan, Mahiti Gupta, Soniya Goyal, Daizee Talukder, Mohd. Sayeed Akhtar, Raman Kumar, Ahmad Umar, Abdulrab Ahmed M. Alkhanjaf, Sotirios Baskoutas
Journal of Environmental Health Science and Engineering.2023; 22(1): 13. CrossRef
The Validity of Benchmark Dose Limit Analysis for Estimating Permissible Accumulation of Cadmium
Soisungwan Satarug, David A. Vesey, Glenda C. Gobe, Aleksandra Đorđević
International Journal of Environmental Research and Public Health.2022; 19(23): 15697. CrossRef
Mitigation of Cadmium Toxicity through Modulation of the Frontline Cellular Stress Response
Soisungwan Satarug, David A. Vesey, Glenda C. Gobe
Stresses.2022; 2(3): 355. CrossRef
Evidence for Ovarian and Testicular Toxicities of Cadmium and Detoxification by Natural Substances
Martin Massányi, Soisungwan Satarug, Roberto Madeddu, Robert Stawarz, Peter Massányi
Stresses.2021; 2(1): 1. CrossRef
Particulate matter pollution and hospital outpatient visits for endocrine, digestive, urological, and dermatological diseases in Nanjing, China
Ce Wang, Guangcan Zhu, Lei Zhang, Kai Chen
Environmental Pollution.2020; 261: 114205. CrossRef
Cadmium and Lead Exposure, Nephrotoxicity, and Mortality
Soisungwan Satarug, Glenda C. Gobe, David A. Vesey, Kenneth R. Phelps
Toxics.2020; 8(4): 86. CrossRef
Cement plant emissions and health effects in the general population: a systematic review
Elena Raffetti, Michele Treccani, Francesco Donato
Chemosphere.2019; 218: 211. CrossRef

502 View
4 Download
6 Web of Science
7 Crossref

Review

Evaluation of mercury exposure level, clinical diagnosis and treatment for mercury intoxication: Byeong-Jin Ye, Byoung-Gwon Kim, Man-Joong Jeon, Se-Yeong Kim, Hawn-Cheol Kim, Tae-Won Jang, Hong-Jae Chae, Won-Jun Choi, Mi-Na Ha, Young-Seoub Hong; Ann Occup Environ Med 2016;28:5. Published online January 22, 2016; DOI: https://doi.org/10.1186/s40557-015-0086-8

Abstract PDF

Mercury occurs in various chemical forms, and it is different to health effects according to chemical forms. In consideration of the point, the evaluation of the mercury exposure to human distinguished from occupational and environmental exposure.

With strict to manage occupational exposure in factory, it is declined mercury intoxication cases by metallic and inorganic mercury inhalation to occupational exposure. It is increasing to importance in environmental exposure and public health.

The focus on the health impact of exposure to mercury is more on chronic, low or moderate grade exposure—albeit a topic of great controversy—, not high concentration exposure by methylmercury, which caused Minamata disease.

Recently, the issue of mercury toxicity according to the mercury exposure level, health effects as well as the determination of what mercury levels affect health are in the spotlight and under active discussion. Evaluating the health effects and Biomarker of mercury exposure and establishing diagnosis and treatment standards are very difficult.

It can implement that evaluating mercury exposure level for diagnosis by a provocation test uses chelating agent and conducting to appropriate therapy according to the result. but, indications for the therapy of chelating agents with mercury exposure have not yet been fully established.

The therapy to symptomatic patients with mercury poisoning is chelating agents, combination therapy with chelating agents, plasma exchange, hemodialysis, plasmapheresis. But the further evaluations are necessary for the effects and side effects with each therapy.

Citations

Citations to this article as recorded by

Architecture of a novel NIR and switch-on fluorescent chemosensor based on mercapto propanehydrazide-functionalized chromenylium-cyanine for the quantification of mercury(II) in environment and living cells
Vuslat Basan, Yusuf Alcay, Emre Ozdemir, Muhammed Ikbal Gunduz, Berkehan Kura, Nurcan Şenyurt Tuzun, Canan Cil, Abdulhalim Kilic, Ismail Yilmaz
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2025; 329: 125589. CrossRef
Indication of air pollution based on the comparison of mercury and other elements in the faeces of marmots from the Western Carpathians and the Dzungarian Alatau
Martina Haas, Katarína Tomíková, Marián Janiga, Aibek Abduakassov, Zuzana Kompišová Ballová
Environmental Science and Pollution Research.2025; 32(7): 3617. CrossRef
Particle-bound mercury in Saharan dust-loaded particulate matter in Cabo Verde
Eduardo José dos Santos Souza, Khanneh Wadinga Fomba, Sofía Gómez Maqueo Anaya, Kerstin Schepanski, Sandra Maria Freire, Dušan Materić, Thorsten Reemtsma, Hartmut Herrmann
Journal of Hazardous Materials.2025; 487: 137053. CrossRef
Identifying the sources of mercury exposure in dental workers
W Chuthong, S Trakulsrichai, P Sirinara
Occupational Medicine.2025; 74(9): 684. CrossRef
Recent advances in the clinical management of intoxication by five heavy metals: Mercury, lead, chromium, cadmium and arsenic
Mahdi Balali-Mood, Nastaran Eizadi-Mood, Hossein Hassanian-Moghaddam, Leila Etemad, Mohammad Moshiri, Maryam Vahabzadeh, Mahmood Sadeghi
Heliyon.2025; 11(4): e42696. CrossRef
Assessing the health hazards of low-dose ethylmercury: Neurochemical and behavioral impacts in neonatal mice through matrix metalloproteinase activation and brain-derived neurotrophic factor release
Min Heui Yoo, Tae-Youn Kim, Ho-Kyong Kim, Ji-Hyun Yoo, Byoung-Seok Lee, Jae-Young Koh
Ecotoxicology and Environmental Safety.2025; 293: 118031. CrossRef
Mercury poisoning in women and infants inhabiting the Gangetic plains of Bihar: risk assessment
Arun Kumar, Radhika Agarwal, Kanhaiya Kumar, Nirmal Kumar Chayal, Govind Kumar, Rajiv Kumar, Mohammad Ali, Abhinav Srivastava, Siddhant Aryal, Tejasvi Pandey, Kumar Sambhav Verma, Dhruv Kumar, Rahul Laxman Gajbhiye, Sameer Dhingra, Naresh Pothuraju, Ramal
BMC Public Health.2025;[Epub] CrossRef
Parkinsonismo en fundidor de oro: intoxicación por mercurio
Steven Zambrano Castro, Patricia Caro Uribe, Leidy Carolina Salazar Chica
Acta Neurológica Colombiana.2025;[Epub] CrossRef
Assessing Heavy Metal Contamination in Food: Implications for Human Health and Environmental Safety
Magdalena Mititelu, Sorinel Marius Neacșu, Ștefan Sebastian Busnatu, Alexandru Scafa-Udriște, Octavian Andronic, Andreea-Elena Lăcraru, Corina-Bianca Ioniță-Mîndrican, Dumitru Lupuliasa, Carolina Negrei, Gabriel Olteanu
Toxics.2025; 13(5): 333. CrossRef
Evaluation of mass mercury poisoning cases occurring in a center in Türkiye: symptomatology, treatment methods, and follow-up processes
Fatih Kurt, Abdullah Akcil, Sengul Cangur, Mustafa Yıldız
European Journal of Pediatrics.2025;[Epub] CrossRef
An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
Kristie B. Yu, Franciscus Chandra, Elena J. Coley-O’Rourke, Erik T. Paulson, Anna Novoselov, David Zhang, Delanie Finnigan, Jorge Paramo, Arlene Lopez-Romero, Tien S. Dong, Amina T. Schartup, Elaine Y. Hsiao
Cell Host & Microbe.2025; 33(5): 621. CrossRef
Innovative Approaches and Evolving Strategies in Heavy Metal Bioremediation: Current Limitations and Future Opportunities
Cristina Firincă, Lucian-Gabriel Zamfir, Mariana Constantin, Iuliana Răut, Maria-Luiza Jecu, Mihaela Doni, Ana-Maria Gurban, Tatiana Eugenia Șesan
Journal of Xenobiotics.2025; 15(3): 63. CrossRef
Unraveling mercury-selenium interactions through metabolomics: Impacts on riverside communities in the Amazon
João Guilherme de Moraes Pontes, Bruno Alves Rocha, Jonas Carneiro Cruz, Gabriel Neves Cezarette, Folorunsho Bright Omage, Ljubica Tasic, Fernando Barbosa
Environmental Pollution.2025; 376: 126398. CrossRef
Ameliorative impacts of sinapic acid against mercuric chloride-induced renal toxicity: role of antioxidants and inflammatory cytokines
Arshad Mehmood, Mohamed Mohamed Soliman, Daklallah A Almalki, Khalid S Alotaibi, Gehan Basiony Ahmed Youssef, Saed Althobaiti
Toxicology Research.2024;[Epub] CrossRef
Health and environmental risk assessment of mercury in outdoor and indoor dust in artisanal and small-scale gold mining area in Amansie-west district in the Ashanti Region of Ghana
Patrick Adu Poku, Sylvester Addai-Arhin, Collins Nimako, Syafran Arrazy, Tia Agustiani, Huiho Jeong, Tetsuro Agusa, Yasuhiro Ishibashi, Jun Kobayashi
Environmental Geochemistry and Health.2024;[Epub] CrossRef
Ion-Selective Electrodes in the Food Industry: Development Trends in the Potentiometric Determination of Ionic Pollutants
Antonio Ruiz-Gonzalez
Electrochem.2024; 5(2): 178. CrossRef
Anthropogenic short-lived halogens increase human exposure to mercury contamination due to enhanced mercury oxidation over continents
Xiao Fu, Xianyi Sun, Oleg Travnikov, Qinyi Li, Chuang Qin, Carlos A. Cuevas, Rafael P. Fernandez, Anoop S. Mahajan, Shuxiao Wang, Tao Wang, Alfonso Saiz-Lopez
Proceedings of the National Academy of Sciences.2024;[Epub] CrossRef
Toxicological and bioremediation profiling of nonessential heavy metals (mercury, chromium, cadmium, aluminium) and their impact on human health: A review
Harsh Sable, Vandana Singh, Vaishali Kumar, Arpita Roy, Soumya Pandit, Kirtanjot Kaur, Sarvesh Rustagi, Sumira Malik
Toxicologie Analytique et Clinique.2024; 36(3): 205. CrossRef
Mercury risk assessment scenarios: exposure from fish dietary behaviors of Katingan River Basin community
Fika R. Mufakhir, Gunawan P. Yoga, Taryono Darusman, Dwi P. Lestari, Desra Arriyadi, Rosetyati R. Utami, Slamet Sumardi, Widi Astuti, Hendra Prasetia
International Journal of Environmental Health Research.2024; 34(9): 3317. CrossRef
Review and assessment of mercury contamination and risk in sediment and food chain near a chlor-alkali plant
Sedigheh Mohamadi, Mohsen Saeedi
Emerging Contaminants.2024; 10(4): 100384. CrossRef
Maternal exposure to bisphenols, phthalates, perfluoroalkyl acids, and trace elements and their associations with gestational diabetes mellitus in the APrON cohort
Munawar Hussain Soomro, Gillian England-Mason, Anthony J.F. Reardon, Jiaying Liu, Amy M. MacDonald, David W. Kinniburgh, Jonathan W. Martin, Deborah Dewey
Reproductive Toxicology.2024; 127: 108612. CrossRef
Baseline characteristics including blood and urine metal levels in the Trial to Assess Chelation Therapy 2 (TACT2)
Ana Navas-Acien, Regina M. Santella, Bonnie R. Joubert, Zhen Huang, Yuliya Lokhnygina, Francisco Ujueta, Irina Gurvich, Nancy J. LoIacono, Filippo Ravalli, Cynthia D. Ward, Jeffery M. Jarrett, Alfonsina De Leon Salazar, Robin Boineau, Teresa L.Z. Jones, D
American Heart Journal.2024; 273: 72. CrossRef
Seasonal and age-dependent differences in mercury concentrations in Apodemus sp. in the north-western region of Slovakia
Lenka Zábojníková
Environmental Science and Pollution Research.2024; 31(7): 10521. CrossRef
Complementary and Alternative Medicine Use and Glomerular Disease: A Contemporary Case Series
Prem Kumar Devaraju, Jayalakshmi Seshadri, Chelvamalai Muthukumaran Balasubramanian, Anila Abraham Kurien, Guhan Senthilkumaran, Vaishanavi Devi Rajarathinam, Vijayakumar Stanlybai Jibia, Vinoj Murugesan, Tanuj Moses Lamech, Dineshkumar Thanigachalam, Sak
Kidney Medicine.2024; 6(6): 100827. CrossRef
Surgical Management of Iatrogenic Mercury Poisoning From Subcutaneous Injection Into the Arm
Evan C. Bowen, Katherine C. Benedict, John M. Sullivan, Katherine E. Baker, Morgan E. Schock, Marc E. Walker
Annals of Plastic Surgery.2024; 93(2): 205. CrossRef
Acute onset parkinsonism after consumption of traditional Chinese medicine: A cause for vigilance
Ko-Ying Kuo, Ying-Sheng Li, Poyin Huang
Heliyon.2024; 10(11): e31628. CrossRef
Should ebselen be considered for the treatment of mercury intoxication? A minireview
Nilda V. Barbosa, Michael Aschner, Alexey A. Tinkov, Marcelo Farina, João Batista Teixeira da Rocha
Toxicology Mechanisms and Methods.2024; 34(1): 1. CrossRef
Public health assessment of Kenyan ASGM communities using multi-element biomonitoring, dietary and environmental evaluation
Maureene Auma Ondayo, Michael J. Watts, Olivier S. Humphrey, Odipo Osano
Ecotoxicology and Environmental Safety.2024; 277: 116323. CrossRef
MEASUREMENT OF PERSISTENT ORGANIC POLLUTANTS, PERFLUORINATED COMPOUNDS, AND TOXIC METALS IN THE BLOOD OF HUMBOLDT PENGUINS (SPHENISCUS HUMBOLDTI) AT PUNTA SAN JUAN, PERU USING DRIED BLOOD SPOTS
Michael J. Adkesson, Alan Shlosberg, Andreas F. Lehner, Wilson K. Rumbeiha, Susana Cárdenas-Alayza, Marco Cardeña-Mormontoy, Kurunthachalam Kannan
Journal of Zoo and Wildlife Medicine.2024;[Epub] CrossRef
Exposure to heavy metals and neurocognitive function in adults: a systematic review
Raed H. Althomali, Manal A. Abbood, Ebraheem Abdu Musad Saleh, Laylo Djuraeva, Barno Sayfutdinovna Abdullaeva, Ruqayah Taher Habash, Muataz S. Alhassan, Ahmed Hussien Radie Alawady, Ali Hashiem Alsaalamy, Moslem Lari Najafi
Environmental Sciences Europe.2024;[Epub] CrossRef
Comparative analysis of the primary morbidity in the population in the territory of accumulated risk over the post-operation period of a chemical enterprise
Inna V. Mylnikova, Oksana V. Ushakova, Natalya V. Efimova, Elena V. Katamanova
Hygiene and sanitation.2024; 103(9): 932. CrossRef
A Rare Case of Intravenous Mercury Poisoning in a 35 Year Old Male
Saket S. Toshniwal, Sourya Acharya, Sunil Kumar, Kashish Khurana, Faizan Khan
Toxicology International.2024; : 621. CrossRef
Literature review of the potential harm and mechanisms of mercury poisoning related to cosmetics
Shuqi Jiang
American Journal of Translational Research.2024; 16(10): 6064. CrossRef
Long-term follow-up after acute mercury poisoning-induced pneumonitis following cinnabar heating: A rare case report
Khoa Nguyen-Dang, Anh-Thu Dau-Nguyen, Nguyen Tran-Ngoc, Ngoc Duong-Minh, Thong Dang-Vu, Sang Nguyen-Ngoc, Nam Vu-Hoai, Hung Le-Quoc
Medicine.2024; 103(50): e41013. CrossRef
A photoluminescent and electrochemiluminescent probe based on an iridium(iii) complex with a boronic acid-functionalised ancillary ligand for the selective detection of mercury(ii) ions
Kyoung-Rok Kim, Jinrok Oh, Jong-In Hong
The Analyst.2023; 148(22): 5619. CrossRef
Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the available evidence in relation to the potential obesogenic activity of certain chemical compounds that may be present in foods
Ana María Rivas Velasco, Irene Bretón Lesmes, Araceli Díaz Perales, Ángel Gil Izquierdo, María José González Muñoz, Victoria Moreno Arribas, María del Puy Portillo Baquedano, Silvia Pichardo Sánchez
Food Risk Assess Europe.2023;[Epub] CrossRef
Colorimetric detection of mercury (Hg2+) using UV–vis spectroscopy and digital image analysis based on gold nanoparticles functionalized with bromelain enzyme
Nurul Azreen Suhaidi, Mohd Izuan Effendi Halmi, Asraf Alif Rashidi, Mohd Firdaus Mohd Anuar, Khairil Mahmud, Norzila Kusnin, Siti Salwa Abd Gani, Mohd Yunus Abd Shukor
3 Biotech.2023;[Epub] CrossRef
The switchable fluorescent detection of mercury, copper, and iodine in real water samples using bola-amphiphilic-tetraphenylethene
Sinan Bayindir, Abdullah Saleh Hussein, Ferruh Lafzi, Mahmut Toprak
Journal of Molecular Liquids.2023; 382: 121939. CrossRef
Human biomonitoring of environmental contaminants in Gulf Countries – current status and future directions
Raghad Khaled, Shahd Elabed, Asmaa Masarani, Anfal Almulla, Shamsa Almheiri, Rinsha Koniyath, Lucy Semerjian, Khaled Abass
Environmental Research.2023; 236: 116650. CrossRef
Antioxidant Supplementation Alleviates Mercury-Induced Cytotoxicity and Restores the Implantation-Related Functions of Primary Human Endometrial Cells
Andrea Palomar, Alicia Quiñonero, Yassmin Medina-Laver, Roberto Gonzalez-Martin, Silvia Pérez-Debén, Pilar Alama, Francisco Domínguez
International Journal of Molecular Sciences.2023; 24(10): 8799. CrossRef
Hg Content in EU and Non-EU Processed Meat and Fish Foods
Vincenzo Nava, Giuseppa Di Bella, Francesco Fazio, Angela Giorgia Potortì, Vincenzo Lo Turco, Patrizia Licata
Applied Sciences.2023; 13(2): 793. CrossRef
Gingerol extract-stabilized silver nanoparticles and their applications: colorimetric and machine learning-based sensing of Hg(ii) and antibacterial properties
Kittiya Plaeyao, Ratchaneekorn Kampangta, Yuparat Korkokklang, Chanon Talodthaisong, Apichart Saenchoopa, Saengrawee Thammawithan, Krailikhit Latpala, Rina Patramanon, Navaphun Kayunkid, Sirinan Kulchat
RSC Advances.2023; 13(29): 19789. CrossRef
A method for reliable quantification of mercury in occupational and environmental medical urine samples by inductively coupled plasma mass spectrometry
Martin Winter, Frederik Lessmann, Volker Harth
Analytical Methods.2023; 15(16): 2030. CrossRef
A brief study on the role of cerium oxide nanoparticles in growth and alleviation of mercury-induced stress in Vigna radiata and soil bacteria Bacillus coagulans
Sampurna Mukherjee, Suresh Babu Krishnamoorthy, Rengaraj Subrayan, Arunava Goswami, Sutanuka Mitra
Environmental Science and Pollution Research.2023; 30(29): 73952. CrossRef
Assessing the Correlation between Blood Trace Element Concentrations, Picky Eating Habits, and Intelligence Quotient in School-Aged Children
Abdullah A. Saati, Heba M. Adly
Children.2023; 10(7): 1249. CrossRef
Blood and Urinary Metal Levels among Exclusive Marijuana Users in NHANES (2005–2018)
Katlyn E. McGraw, Anne E. Nigra, Joshua Klett, Marisa Sobel, Elizabeth C. Oelsner, Ana Navas-Acien, Xin Hu, Tiffany R. Sanchez
Environmental Health Perspectives.2023;[Epub] CrossRef
Genome-Wide Association Study of Blood Mercury in European Pregnant Women and Children
Kyle Dack, Mariona Bustamante, Caroline M. Taylor, Sabrina Llop, Manuel Lozano, Paul Yousefi, Regina Gražulevičienė, Kristine Bjerve Gutzkow, Anne Lise Brantsæter, Dan Mason, Georgia Escaramís, Sarah J. Lewis
Genes.2023; 14(12): 2123. CrossRef
Acute Mercury Poisoning in Young Children: When to Treat?
Sudha Chandelia, Viresh Vohra, Shankar Prasad, Mithlesh Kumar Tiwari, Karthi Nallasamy, Suresh Kumar Angurana
Indian Journal of Pediatrics.2023; 90(6): 629. CrossRef
Electrochemical separation and purification of no-carrier-added 177Lu for radiopharmaceutical preparation: Translation from bench to bed
Sourav Patra, Rubel Chakravarty, Khajan Singh, K.V. Vimalnath, Sudipta Chakraborty
Chemical Engineering Journal Advances.2023; 14: 100444. CrossRef
Suicidal intoxication with mercury chloride
Sławomir Majdanik, Barbara Potocka-Banaś, Sebastian Glowinski, Sylwester Luzny
Forensic Toxicology.2023; 41(2): 304. CrossRef
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires
Bela Barros, Marta Oliveira, Simone Morais
Journal of Toxicology and Environmental Health, Part B.2023; 26(3): 127. CrossRef
Barbituric acid appended fluorescent sensor for the detection of Cu2+/Hg2+ ions along with real-life utility in recognition of malathionin food samples and fingerprint imaging
Gitanjali Jindal, Navneet Kaur
Journal of Photochemistry and Photobiology A: Chemistry.2023; 434: 114238. CrossRef
A methionine biomolecule-modified chromenylium-cyanine fluorescent probe for the analysis of Hg2+ in the environment and living cells
Yusuf Alcay, Emre Ozdemir, Mustafa Semih Yildirim, Utku Ertugral, Ozgur Yavuz, Hulya Aribuga, Yilmaz Ozkilic, Nurcan Şenyurt Tuzun, Ayse Buse Ozdabak Sert, Fatma Nese Kok, Ismail Yilmaz
Talanta.2023; 259: 124471. CrossRef
Associations between exposure to cadmium, lead, mercury and mixtures and women’s infertility and long-term amenorrhea
Maria McClam, Jihong Liu, Yihan Fan, Tingjie Zhan, Qiang Zhang, Dwayne E. Porter, Geoffrey I. Scott, Shuo Xiao
Archives of Public Health.2023;[Epub] CrossRef
Spots in Dermatology
Swathy Prasannan, AS Savitha, TS Nagesh
Clinical Dermatology Review.2022; 6(1): 59. CrossRef
Domestic water and accumulating mercury toxicity in the kidney
Raafat Abdeldayem
Applied Water Science.2022;[Epub] CrossRef
Effects of Low-Level Organic Mercury Exposure on Oxidative Stress Profile
Radu Ciprian Tincu, Cristian Cobilinschi, Iulia Alexandra Florea, Ana-Maria Cotae, Alexandru Emil Băetu, Sebastian Isac, Raluca Ungureanu, Gabriela Droc, Ioana Marina Grintescu, Liliana Mirea
Processes.2022; 10(11): 2388. CrossRef
Renaissance mercurial therapy in the mummies of Saint Domenico Maggiore in Naples: a palaeopathological and palaeotoxicological approach
Antonio Fornaciari, Silvio Chericoni, Fabio Stefanelli, Gino Fornaciari, Valentina Giuffra
Archaeological and Anthropological Sciences.2022;[Epub] CrossRef
A Systematic Review of Mercury Exposures from Skin-Lightening Products
Ashley Bastiansz, Jessica Ewald, Verónica Rodríguez Saldaña, Andrea Santa-Rios, Niladri Basu
Environmental Health Perspectives.2022;[Epub] CrossRef
Recurrent Rash in an 11-Year-Old Boy With Pericardial and Pleural Effusions
Allison M. Weisnicht, Ryan Byrne, Erin B. Henkel, Stephen A. Harding, Stefan P. Kostelyna, Deborah Schady, Jamie Lai, Leigh A. Stubbs
Pediatrics.2022;[Epub] CrossRef
Prenatal Mercury Exposure and Infant Weight Trajectories in a UK Observational Birth Cohort
Kyle Dack, Robyn E. Wootton, Caroline M. Taylor, Sarah J. Lewis
Toxics.2022; 11(1): 10. CrossRef
Colorimetric screening of elevated urinary mercury levels by a novel Hg2+-selective probe of resorufin phosphinothioate
Myung Gil Choi, Byung Hoon Yun, Hyeong Min Kim, Sangdoo Ahn, Suk-Kyu Chang
RSC Advances.2022; 12(37): 24107. CrossRef
Heavy metal-induced lipogenic gene aberration, lipid dysregulation and obesogenic effect: a review
Yang Zhou, Frank Peprah Addai, Xinshuang Zhang, Yuelin Liu, Yinfeng Wang, Feng Lin, Alex Tuffour, Jie Gu, Guangxiang Liu, Haifeng Shi
Environmental Chemistry Letters.2022; 20(3): 1611. CrossRef
Functional consequences of lead and mercury exposomes in the heart
Gonzalo Ferreira, Axel Santander, Luisina Chavarría, Romina Cardozo, Florencia Savio, Luis Sobrevia, Garth L. Nicolson
Molecular Aspects of Medicine.2022; 87: 101048. CrossRef
Sensitive fluorescent chemosensor for Hg(II) in aqueous solution using 4’-dimethylaminochalcone
Marco Mellado, Nicole Roldán, Rodrigo Miranda, Luis F. Aguilar, Manuel A. Bravo, Waldo Quiroz
Journal of Fluorescence.2022; 32(4): 1449. CrossRef
Beyond efficiency fever: Preventing lead leakage for perovskite solar cells
Pengfei Wu, Shirong Wang, Xianggao Li, Fei Zhang
Matter.2022; 5(4): 1137. CrossRef
A Reversible Optical Sensor Film for Mercury Ions Discrimination Based on Isoxazolidine Derivative and Exhibiting pH Sensing
Reham Ali, Siwar Ghannay, Sabri Messaoudi, Fahad M. Alminderej, Kaïss Aouadi, Sayed M. Saleh
Biosensors.2022; 12(11): 1028. CrossRef
Mercury pollution in Peru: geographic distribution, health hazards, and sustainable removal technologies
Fernando G. Torres, Gabriel E. De-la-Torre
Environmental Science and Pollution Research.2022; 29(36): 54045. CrossRef
Occupational exposure to mercury from cinnabar enriched sand in workers of Grado Beach, Gulf of Trieste (North-eastern Italy, upper Adriatic Sea)
Luca Cegolon, Giuseppe Mastrangelo, Stefano Covelli, Elisa Petranich, Elena Pavoni, Francesca Larese Filon
Marine Pollution Bulletin.2022; 184: 114057. CrossRef
Mercury and Movement Disorders: The Toxic Legacy Continues
Jacky Ganguly, Dinkar Kulshreshtha, Mandar Jog
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.2022; 49(4): 493. CrossRef
SNS donors as mimic to enzymes, chemosensors, and imaging agents
Poonam Kaswan, Preeti Oswal, Arun Kumar, Chandra Mohan Srivastava, Dipti Vaya, Varun Rawat, Kamal Nayan Sharma, Gyandshwar Kumar Rao
Inorganic Chemistry Communications.2022; 136: 109140. CrossRef
Aptasensors for full body health checkup
Tanu Bhardwaj, Tarun Kumar Sharma
Biosensors and Bioelectronics: X.2022; 11: 100199. CrossRef
Concentration of mercury in human hair and associated factors in residents of the Gulf of Trieste (North-Eastern Italy)
Luca Cegolon, Elisa Petranich, Elena Pavoni, Federico Floreani, Nicolò Barago, Elisa Papassissa, Francesca Larese Filon, Stefano Covelli
Environmental Science and Pollution Research.2022; 30(8): 21425. CrossRef
Heavy Metals, Halogenated Hydrocarbons, Phthalates, Glyphosate, Cordycepin, Alcohol, Drugs, and Herbs, Assessed for Liver Injury and Mechanistic Steps
Rolf Teschke, Tran Dang Xuan
Frontiers in Bioscience-Landmark.2022;[Epub] CrossRef
Ziziphus spina-christi Leaf Extract Mitigates Mercuric Chloride-induced Cortical Damage in Rats
Rafa S. Almeer, Saad Alkahtani, Saud Alarifi, Ahmed E. Abdel Moneim, Saba Abdi, Gadah Albasher
Combinatorial Chemistry & High Throughput Screening.2021; 25(1): 103. CrossRef
Maternal Urinary Metal and Metalloid Concentrations in Association with Oxidative Stress Biomarkers
Pahriya Ashrap, Deborah J. Watkins, Ginger L. Milne, Kelly K. Ferguson, Rita Loch-Caruso, Jennifer Fernandez, Zaira Rosario, Carmen M. Vélez-Vega, Akram Alshawabkeh, José F. Cordero, John D. Meeker
Antioxidants.2021; 10(1): 114. CrossRef
Changes in the renal function after acute mercuric chloride exposure in the rat are associated with renal vascular endothelial dysfunction and proximal tubule NHE3 inhibition
João Vitor dos Anjos Vieira, Vinicius Bermond Marques, Luiza Valli Vieira, Renato de Oliveira Crajoinas, Maria Heloisa Massola Shimizu, Antonio Carlos Seguro, Maria Tereza Weitzel Dias Carneiro, Adriana Castello Costa Girardi, Dalton Valentim Vassallo, Le
Toxicology Letters.2021; 341: 23. CrossRef
Children with Amalgam Dental Restorations Have Significantly Elevated Blood and Urine Mercury Levels
Lei Yin, Simon Lin, Anne O Summers, Van Roper, Matthew J Campen, Xiaozhong Yu
Toxicological Sciences.2021; 184(1): 104. CrossRef
Speciation analysis of mercury employing volatile species generation: Approaches to reliable determination in blood and hair
Inga Petry-Podgórska, Věra Schrenková, Michaela Migašová, Tomáš Matoušek, Jan Kratzer
Microchemical Journal.2021; 170: 106606. CrossRef
Assessment of radioactivity and heavy metals in water sources from Artisanal mining areas of Anka, Northwest Nigeria
Mbet Amos Akpanowo, Nasiru Adebayo Bello, Ibrahim Umaru, Shekwonyadu Iyakwari, Emmanuel Joshua, Samson Yusuf, Godwin Bassey Ekong
Scientific African.2021; 12: e00761. CrossRef
Metals and Metal-Nanoparticles in Human Pathologies: From Exposure to Therapy
Joanna Izabela Lachowicz, Luigi Isaia Lecca, Federico Meloni, Marcello Campagna
Molecules.2021; 26(21): 6639. CrossRef
Functionalized magnetic nanoparticles Fe3O4@SiO2@PTA (PTA = (2-pyrimidylthio)acetic acid) for efficient removal of mercury from water
Gaurav Vyas, Shreya Bhatt, Parimal Paul
Colloids and Surfaces A: Physicochemical and Engineering Aspects.2021; 611: 125861. CrossRef
Identification of metal binding motifs in protein frameworks to develop novel remediation strategies for Hg2+ and Cr(VI)
J. Sreeshma, C. Sudandiradoss
BioMetals.2021; 34(3): 621. CrossRef
Comparison of Ultrastructural Features Between Patients with Mercury-associated Membranous Nephropathy and Idiopathic Membranous Nephropathy
Ai-bo Qin, Zi-shan Lin, Su-xia Wang, Hui Wang, Zhao Cui, Fu-de Zhou, Ming-hui Zhao
The American Journal of the Medical Sciences.2021; 361(3): 327. CrossRef
Recent Advances on the Development of Chemosensors for the Detection of Mercury Toxicity: A Review
Shiva Prasad Kollur, Chandan Shivamallu, Shashanka K. Prasad, Ravindra Veerapur, Sharanagouda S. Patil, Charley A. Cull, Johann F. Coetzee, Raghavendra G. Amachawadi
Separations.2021; 8(10): 192. CrossRef
Heavy Metals in Indian Traditional Systems of Medicine: A Systematic Scoping Review and Recommendations for Integrative Medicine Practice
Sanchari Mukhopadhyay, Shalu Elizabeth Abraham, Bharath Holla, Kishore Kr Ramakrishna, Kamala Lakshmi Gopalakrishna, Akhila Soman, Umesh C. Chikkanna, Muchukunte Mukunda Srinivas Bharath, Hemant Bhargav, Shivarama Varambally, Bangalore Nanjundaiah Gangadh
The Journal of Alternative and Complementary Medicine.2021; 27(11): 915. CrossRef
Characteristics and treatment of elemental mercury intoxication: A case series
Kelly Johnson‐Arbor, Eshetu Tefera, John Farrell
Health Science Reports.2021;[Epub] CrossRef
Imaging Microstructural Damage and Alveolar Bone Loss in Rats Systemically Exposed to Methylmercury: First Experimental Evidence
Géssica de Oliveira Lopes, Walessa Alana Bragança Aragão, Leonardo Oliveira Bittencourt, Bruna Puty, Armando Pereira Lopes, Sávio Monteiro dos Santos, Marta Chagas Monteiro, Edivaldo Herculano Corrêa de Oliveira, Márcia Cristina Freitas da Silva, Rafael R
Biological Trace Element Research.2021; 199(10): 3707. CrossRef
Analysis of Cadmium, Mercury, and Lead Concentrations in Erythrocytes of Renal Transplant Recipients from Northwestern Poland
Aleksandra Wilk, Maciej Romanowski, Barbara Wiszniewska
Biology.2021; 10(1): 62. CrossRef
The Aging Kidney—As Influenced by Heavy Metal Exposure and Selenium Supplementation
Jan Aaseth, Jan Alexander, Urban Alehagen, Alexey Tinkov, Anatoly Skalny, Anders Larsson, Guido Crisponi, Valeria Marina Nurchi
Biomolecules.2021; 11(8): 1078. CrossRef
Adsorption and Removal of Hazardous Metallic Elements Hg ⁰, Ni ⁰ and Pb ⁰: A DFT Study on g-C ₃N ₄ Monolayer Modified with Pt _n (n=1 - 7) Clusters
Siying Zhong, Shao-Yi Wu, Gao-Jun Zhang, Jia-Xing Guo, Li Yan
SSRN Electronic Journal .2021;[Epub] CrossRef
Cellular and Molecular Mechanisms Mediating Methylmercury Neurotoxicity and Neuroinflammation
João P. Novo, Beatriz Martins, Ramon S. Raposo, Frederico C. Pereira, Reinaldo B. Oriá, João O. Malva, Carlos Fontes-Ribeiro
International Journal of Molecular Sciences.2021; 22(6): 3101. CrossRef
Methylmercury plus Ethanol Exposure: How Much Does This Combination Affect Emotionality?
Diandra Araújo Luz, Sabrina de Carvalho Cartágenes, Cinthia Cristina Sousa de Menezes da Silveira, Bruno Gonçalves Pinheiro, Kissila Márvia Matias Machado Ferraro, Luanna de Melo Pereira Fernandes, Enéas Andrade Fontes-Júnior, Cristiane do Socorro Ferraz
International Journal of Molecular Sciences.2021; 22(23): 13131. CrossRef
Unveiling the Features of Mercury-Associated Minimal Change Disease: Comparison with Primary Minimal Change Disease
Ai-bo Qin, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao
Kidney Diseases.2021; 7(2): 156. CrossRef
Mercury and Prenatal Growth: A Systematic Review
Kyle Dack, Matthew Fell, Caroline M. Taylor, Alexandra Havdahl, Sarah J. Lewis
International Journal of Environmental Research and Public Health.2021; 18(13): 7140. CrossRef
The “wing-heeled” traveler
Taylor Kain, Jordan Weinstein, Aaron Thompson, Andrea K. Boggild
Tropical Diseases, Travel Medicine and Vaccines.2020;[Epub] CrossRef
Mercury exposure and nonmelanoma skin cancer: what're the odds?
N. Taylor
British Journal of Dermatology.2020; 183(3): 413. CrossRef
Mercury intoxication resembling pediatric rheumatic diseases: case series and literature review
Mehmet Yildiz, Amra Adrovic, Aybuke Gurup, Esra Karabag Yilmaz, Yavuz Ozer, Oya Koker, Sezgin Sahin, Ertugrul Kiykim, Nur Canpolat, Kenan Barut, Ozgur Kasapcopur
Rheumatology International.2020; 40(8): 1333. CrossRef
Comparing the Neuroprotective Effects of Aqueous and Methanolic Extracts of Vernonia Amygdalina on the Cerebellum of Adult Male Wistar Rats
Ugochukwu Samuel Aguwa, Somadina M Okeke, Chijioke M Okeke, Chinyere E Eze, Benedict Nzube Obinwa, Morris Izuogu, Felix Ogbo Ovie, Darlington Nnamdi Onyejike, Doris Kasarachi Ogbuokiri, Damian N Ezejindu
International Annals of Science.2020; 9(1): 145. CrossRef
Broken thermometer in foot: a source of mercury poisoning
Peyman Erfantalab, Nasim Zamani, Hossein Hassanian-Moghaddam
Tropical Doctor.2020; 50(1): 83. CrossRef
Status of mercury accumulation in agricultural soils across China (1976–2016)
Xingyuan Li, Jingru Zhang, Yiwei Gong, Shuhui Yang, Mai Ye, Xuan Yu, Jin Ma
Ecotoxicology and Environmental Safety.2020; 197: 110564. CrossRef
In Situ Doping-Enabled Metal and Nonmetal Codoping in Graphene Quantum Dots: Synthesis and Application for Contaminant Sensing
Aruna N. Nair, Venkata S.N. Chava, Saptasree Bose, Ting Zheng, Srikanth Pilla, Sreeprasad T. Sreenivasan
ACS Sustainable Chemistry & Engineering.2020; 8(44): 16565. CrossRef
A review on nanostructure-based mercury (II) detection and monitoring focusing on aptamer and oligonucleotide biosensors
Samet Şahin, Mustafa Oguzhan Caglayan, Zafer Üstündağ
Talanta.2020; 220: 121437. CrossRef
Blood Mercury Levels in Children with Kawasaki Disease and Disease Outcome
Ling-Sai Chang, Jia-Huei Yan, Jin-Yu Li, Deniz Des Yeter, Ying-Hsien Huang, Mindy Ming-Huey Guo, Mao-Hung Lo, Ho-Chang Kuo
International Journal of Environmental Research and Public Health.2020; 17(10): 3726. CrossRef
Elevated Hair Mercury Levels Are Associated With Neurodevelopmental Deficits in Children Living Near Artisanal and Small‐Scale Gold Mining in Peru
Aaron Reuben, Helena Frischtak, Axel Berky, Ernesto J. Ortiz, Ana Maria Morales, Heileen Hsu‐Kim, Laura L. Pendergast, William K. Pan
GeoHealth.2020;[Epub] CrossRef
Current issues of environmental mercury pollution (review)
V. N. Rakitskii, T. A. Synitskaya, Sergeii V. Skupnevskii
Hygiene and sanitation.2020; 99(5): 460. CrossRef
Evaluation of kidney function and oxidative stress biomarkers in prolonged occupational exposure with mercury in dentists
Mohsen Yazdanian, Ghader Ghanizadeh, Shirin Rastgoo, Sayyed Morteza Hosseini Shokouh
Gene Reports.2020; 19: 100627. CrossRef
Is there evidence of weathering among women seeking fertility treatments?: Evidence and insights
Katherine Tierney
Social Science & Medicine.2020; 247: 112816. CrossRef
An unusual cause of nephrotic syndrome in a 10-year-old girl: Answers
Yu Bao, Huijun Shen
Pediatric Nephrology.2020; 35(7): 1219. CrossRef
Mercury Exposure Among Artisanal and Small-Scale Gold Miners in Four Regions in Uganda
Mercy Wendy Wanyana, Friday E. Agaba, Deogratias K. Sekimpi, Victoria N. Mukasa, Geoffrey N. Kamese, Nkonge Douglas, John C. Ssempebwa
Journal of Health and Pollution.2020;[Epub] CrossRef
Blood Response to Mercury Exposure in Athletic Horse From Messina, Italy
Francesco Fazio, Nicola Cicero, Giuseppe Piccione, Claudia Giannetto, Patrizia Licata
Journal of Equine Veterinary Science.2020; 84: 102837. CrossRef
Current issues of environmental mercury pollution (review)
V. N. Rakitskii, T. A. Synitskaya, Sergeii V. Skupnevskii
Hygiene and sanitation.2020; 99(5): 460. CrossRef
Regulation of Single-Channel Conductance of Voltage-Dependent Anion Channel by Mercuric Chloride in a Planar Lipid Bilayer
Chetan Malik, Subhendu Ghosh
The Journal of Membrane Biology.2020; 253(4): 357. CrossRef
Lead and Mercury Exposure and Related Health Problems in Metal Artisan Workplaces and High-Risk Household Contacts in Thimphu, Bhutan
Adeep Monger, Karma Wangdi
The Scientific World Journal.2020; 2020: 1. CrossRef
The interrelation of neurophysiological, psychological, and biochemical indicators in patients with occupational chronic mercury intoxication suffering from insomnia
Elena V. Katamanova, Elena N. Korchuganova, Natalia V. Slivnitsyna, Irina V. Kudaeva, Oleg L. Lakhman
Russian Journal of Occupational Health and Industrial Ecology.2020; 60(12): 904. CrossRef
Toxic Metals Depuration Profiles from a Population Adjacent to a Military Target Range (Vieques) and Main Island Puerto Rico
Héctor Jirau-Colón, Ashley Cosme, Víctor Marcial-Vega, Braulio Jiménez-Vélez
International Journal of Environmental Research and Public Health.2019; 17(1): 264. CrossRef
A Case of Accidental Mercury Intoxication
Olivia L. Kamensky, Destiny Horton, Donald P. Kingsley, Christy C. Bridges
The Journal of Emergency Medicine.2019; 56(3): 275. CrossRef
Endoplasmic reticulum stress participates in the pathophysiology of mercury-caused acute kidney injury
Plácido Rojas-Franco, Margarita Franco-Colín, Alejandra Paola Torres-Manzo, Vanessa Blas-Valdivia, María del Rocio Thompson-Bonilla, Sinan Kandir, Edgar Cano-Europa
Renal Failure.2019; 41(1): 1001. CrossRef
Lethal concentrations of mercury or lead do not affect coagulation kinetics in human plasma
Vance G. Nielsen
Journal of Thrombosis and Thrombolysis.2019; 48(4): 697. CrossRef
The Clinical Importance of the Mercury Problem in Artisanal Small-Scale Gold Mining
Justice Afrifa, Yeboah Kwaku Opoku, Eric Ofori Gyamerah, George Ashiagbor, Rosemary Doe Sorkpor
Frontiers in Public Health.2019;[Epub] CrossRef
Ziziphus spina-christi Leaf Extract Suppressed Mercury Chloride-Induced Nephrotoxicity via Nrf2-Antioxidant Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling
Rafa S. Almeer, Gadah Albasher, Fatimah Alotibi, Saud Alarifi, Daoud Ali, Saad Alkahtani
Oxidative Medicine and Cellular Longevity.2019; 2019: 1. CrossRef
Genetically encoded FRET-based optical sensor for Hg2+ detection and intracellular imaging in living cells
Neha Soleja, Mohamad Aman Jairajpuri, Aarfa Queen, Mohd Mohsin
Journal of Industrial Microbiology and Biotechnology.2019; 46(12): 1669. CrossRef
Impaired participation of potassium channels and Na+/K+‐ATPase in vasodilatation due to reduced nitric oxide bioavailability in rats exposed to mercury
Tatiani Botelho, Vinícius B. Marques, Maylla R. Simões, Patricia R. do Val Lima, Fabiana V. Simões, Dalton V. Vassallo, Leonardo dos Santos
Basic & Clinical Pharmacology & Toxicology.2019; 124(2): 190. CrossRef
Mercury-associated glomerulonephritis: a retrospective study of 35 cases in a single Chinese center
Ai-bo Qin, Tao Su, Su-xia Wang, Fan Zhang, Fu-de Zhou, Ming-hui Zhao
BMC Nephrology.2019;[Epub] CrossRef
The life-threatening rash of poisoning
Michael Joseph Lavery, Ronni Wolf
Clinics in Dermatology.2019; 37(2): 136. CrossRef
Mercury levels in human population from a mining district in Western Colombia
Harry Gutiérrez-Mosquera, S.B. Sujitha, M.P. Jonathan, S.K. Sarkar, Fairy Medina-Mosquera, Helcias Ayala-Mosquera, Gladis Morales-Mira, Laura Arreola-Mendoza
Journal of Environmental Sciences.2018; 68: 83. CrossRef
Mercury poisoning in a fisherman working on a pelagic fishing vessel due to excessive tuna consumption
Ji-Sung Ahn, Kyung Wook Kang, Won-Yang Kang, Hyeong-Min Lim, Seunghyeon Cho, Jai-Dong Moon, Won-Ju Park
Journal of Occupational Health.2018; 60(1): 89. CrossRef
The Content of Mercury in Herbal Dietary Supplements
Barbara Brodziak-Dopierała, Agnieszka Fischer, Wioletta Szczelina, Jerzy Stojko
Biological Trace Element Research.2018; 185(1): 236. CrossRef
The associations between blood mercury levels and shark meat intake among workers in Gyeongsangbuk-do
Gun Il Park, Young Seok Byun, Man Joong Jeon, Joon Sakong
Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef
A review: Aptamer-based analytical strategies using the nanomaterials for environmental and human monitoring of toxic heavy metals
Leila Farzin, Mojtaba Shamsipur, Shahab Sheibani
Talanta.2017; 174: 619. CrossRef
Metal Ion Toxins and Brain Aquaporin-4 Expression: An Overview
Adriana Ximenes-da-Silva
Frontiers in Neuroscience.2016;[Epub] CrossRef
Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity
Daqian Yang, Xiao Tan, Zhanjun Lv, Biying Liu, Ruiqi Baiyun, Jingjing Lu, Zhigang Zhang
Scientific Reports.2016;[Epub] CrossRef
Assessment of the Cardiac Autonomic Nervous System in Mercury-Exposed Individuals via Post-Exercise Heart Rate Recovery
Omer Hinc Yilmaz, Ugur Nadir Karakulak, Engin Tutkun, Ceylan Bal, Meside Gunduzoz, Emine Ercan Onay, Mehmet Ayturk, Mujgan Tek Ozturk, Mehmet Erdem Alaguney
Medical Principles and Practice.2016; 25(4): 343. CrossRef

2,818 View
40 Download
141 Web of Science
133 Crossref

Case Report

Four Cases of Abnormal Neuropsychological Findings in Children with High Blood Methylmercury Concentrations: Young-Seoub Hong, Dae-Seon Kim, Seung-Do Yu, Seong-Hwan Kim, Jong-Kuk Kim, Yu-Mi Kim, Jae-Ho Yu, Ji-Hyun Jung, Byoung-Gwon Kim; Ann Occup Environ Med 2013;25:18. Published online September 24, 2013; DOI: https://doi.org/10.1186/2052-4374-25-18

Abstract PDF

Background

Methylmercury (MeHg) easily crosses the blood–brain barrier and accumulates in the brain. Accumulated MeHg will cause neurological symptoms. We report four pediatric cases of neuropsychological findings with high blood MeHg concentrations.

Case presentation

Four children were admitted for follow-up study because their total mercury (THg) concentration in the blood was found to be high during a national survey. Case 1 was a 9-year-old female with a 16.6 μg/ℓ blood THg concentration in the survey. During admission, the blood THg, hair THg, and blood MeHg concentration(mercury indices) were 21.4 μg/ℓ, 7.2 μg/g, and 20.1 μg/ℓ, respectively. In our neuropsychological examination, cognitive impairment and attention deficit were observed. Her diet included fish intake 2–3 times per week, and she had been diagnosed with epilepsy at 3 years of age. Case 2 was a 12-year-old male with blood THg of 15.4 μg/ℓ in the survey and the mercury indices were 12.7 μg/ℓ, 5.7 μg/g, and 11.8 μg/ℓ, respectively, on admission. He was also observed to have attention-deficit/hyperactivity disorder. Case 3 was a 10-year-old male child with blood THg of 17.4 μg/ℓ in the survey, and the mercury indices on admission were 21.6 μg/ℓ, 7.5 μg/g and 21.5 μg/ℓ, respectively. In his case, mild attention deficit was observed. Case 4 was a 9-year-old male with blood THg of 20.6 μg/ℓ in the survey and the mercury indices were 18.9 μg/ℓ, 8.3 μg/g, and 14.4 μg/ℓ, respectively, on admission. Mild attention difficulty was observed.

Conclusion

We suggest that fish consumption may be the main source of MeHg exposure, and that MeHg may have been the cause of the neuropsychological deficits in these cases.

Citations

Citations to this article as recorded by

Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health
Ujang Tinggi, Anthony V. Perkins
Nutrients.2022; 14(24): 5308. CrossRef
Characteristics, Treatment, and Prognosis of Elemental Mercury Intoxication in Children
Deniz Güven, İmran Özbek
Pediatric Emergency Care.2022; 38(10): 481. CrossRef
Oral methylmercury intoxication aggravates cardiovascular risk factors and accelerates atherosclerosis lesion development in ApoE knockout and C57BL/6 mice
Janayne L. Silva, Paola C. L. Leocádio, Jonas M. Reis, Gianne P. Campos, Luciano S. A. Capettini, Giselle Foureaux, Anderson J. Ferreira, Cláudia C. Windmöller, Flávia A. Santos, Reinaldo B. Oriá, Maria E. Crespo-López, Jacqueline I. Alvarez-Leite
Toxicological Research.2021; 37(3): 311. CrossRef
Mercury intoxication resembling pediatric rheumatic diseases: case series and literature review
Mehmet Yildiz, Amra Adrovic, Aybuke Gurup, Esra Karabag Yilmaz, Yavuz Ozer, Oya Koker, Sezgin Sahin, Ertugrul Kiykim, Nur Canpolat, Kenan Barut, Ozgur Kasapcopur
Rheumatology International.2020; 40(8): 1333. CrossRef

416 View
1 Download
4 Web of Science
4 Crossref

Original Article

The Relationship Between Amalgam Tooth Fillings and Concentration of Blood Mercury in Elementary School Students in Korea: Kyu Hwa Lee, Man Joong Jeon, Yun Chul Hong, Jong Han Leem, Mi Na Ha, Ho Jang Kwon, Joon Sakong; Korean Journal of Occupational and Environmental Medicine 2011;23(4):420-427. Published online December 31, 2011; DOI: https://doi.org/10.35371/kjoem.2011.23.4.420

Abstract PDF: OBJECTIVES
The adverse health effects of mercury in dental amalgam have not yet been clarified. This study was conducted to examine the effects of dental amalgam on the concentration of blood mercury in Korean children.
METHODS
A total of 1,275 students were enrolled in the elementary school in Seoul, Incheon, and Daegu. The number and location of dental amalgam filling of teeth were ascertained by oral examination. Dietary habits-including frequency of seafood intake-and other demographic factors were obtained from the children's parents. The concentration of blood mercury was measured by an atomic absorption spectrophotometer to which a hydride generator was installed.
RESULTS
The geometric mean of blood mercury concentration was 1.91 microg/L. It was found that elementary school students in Seoul and the 4th grade elementary school students have the lowest concentration of blood mercury among the study groups. Both linear and secondary linear increase of the concentration of blood mercury, depending on the number of dental amalgam fillings, were statistically significant (p-trend < 0.01, p-quadratic < 0.01). As a result of multiple regression analysis on the blood mercury concentration of elementary school students, the regression coefficient (beta) of a dental amalgam filling was found to be 0.027 (standard error = 0.014, p = 0.048).
CONCLUSIONS
In children, the dental amalgam fillings were significantly contribute to the concentration of blood mercury. To accurately assess the effect of dental amalgam on the concentration of body mercury, further studies using the concentration of urine mercury are needed.

216 View
0 Download

Original Article

Association of Blood Mercury Level and Neurobehavioral Performance in Korean Elementary School Students: Joon Sakong, Man Joong Jeon, Sung Ho Yun, Yun Chul Hong, Chul Gab Lee, Young Ki Kim, Mina Ha, Ho Jang Kwon; Korean Journal of Occupational and Environmental Medicine 2010;22(4):324-330. Published online December 31, 2010; DOI: https://doi.org/10.35371/kjoem.2010.22.4.324

Abstract PDF

OBJECTIVES
This study was conducted to examine the effect of blood mercury on neurobehavioral performance in Korean elementary school students.
METHODS
We measured the blood mercury concentration in 1,077 elementary school students from Seoul, Busan, Daegu and Gwangju, then the students underwent computerized neurobehavioral test.
RESULTS
The mean concentration of blood mercury of study subjects was 2.10 microg/L. An increased blood mercury was associated with an increased reaction time in digit addition and symbol digit.
CONCLUSIONS
The blood mercury concentration of study subjects was very high compared to findings in a foreign country. We found several associations between blood mercury level and neurobehavioral performance.

Citations

Citations to this article as recorded by

Performance assessment on the Korean Computerized Neurobehavioral Test using a mobile device and a conventional computer: an experimental study
Young Seok Byun, Sung Kyu Park, Joon Sakong, Man Joong Jeon
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Evaluation of reliability of computerized neurobehavioral tests in Korean children
Kyeong-Soo Lee, Man-Joong Jeon, Tae-Yoon Hwang, Chang-Yoon Kim, Joon Sakong
NeuroToxicology.2012; 33(5): 1362. CrossRef

200 View
1 Download
2 Crossref

Original Article

The Effects of the Frequency of Fish Consumption on the Blood Mercury Levels in Koreans: Chan Woo Kim, Young Wook Kim, Chang Ho Chae, Jun Seok Son, Seung Hyun Park, Jae Chul Koh, Dae Seon Kim; Korean Journal of Occupational and Environmental Medicine 2010;22(2):114-121. Published online June 30, 2010; DOI: https://doi.org/10.35371/kjoem.2010.22.2.114

Abstract PDF

OBJECTIVE: We studied two districts in Korea in order to investigate if the frequency of fish consumption has an effect on the blood mercury levels.
METHODS
This survey was conducted on 164 fishing district residents in Geoje city and 219 agricultural district residents in Changwon city from July to August in 2008. The data on the demographic characteristics, the living environment, lifestyle habits and the frequency of fish consumption was collected by interviewers. We used ANOVA to estimate the particular relevance between the frequency of fish consumption and the blood mercury concentration, and other various factors.
RESULTS
The mean total blood mercury level was 6.54+/-4.01 microgram/L for the total study population. Our results were even higher than that of the National Health and Nutrition Examination Survey (USA) in, 2001~2002 and the German Environmental Survey in, 1998. In this study, there was a significant difference for the frequency of eating fish between the groups. (p<0.01, The level of the groups that ate fish 3 to 4 times per week was significantly higher as compared with the level of the other groups that ate fish 2 to 3 times per month and 1 to 2 times per week, respectively). As the frequency of fish consumption increased, so did the blood mercury concentration.
CONCLUSIONS
We found that the blood mercury concentration increases along with fish consumption and this was statistically significant and this fact reveals that fish consumption is positively related to the blood levels of mercury. Accordingly, we need systematic and periodic research on the general population to prevent mercury poisoning, which can be caused by low-level mercury exposure from dietary intake such as chronic fish consumption.

Citations

Citations to this article as recorded by

Infantile allergic diseases: a cohort study prenatal fish intake and mercury exposure context
Surabhi Shah, Hae Soon Kim, Yun-Chul Hong, Hyesook Park, Mina Ha, Yangho Kim, Ji Hyen Lee, Eun-Hee Ha
BMC Public Health.2024;[Epub] CrossRef
Association of Blood Mercury Level with the Risk of Depression According to Fish Intake Level in the General Korean Population: Findings from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008–2013
Kyung Won Kim, Sundara Raj Sreeja, Minji Kwon, Ye Lee Yu, Mi Kyung Kim
Nutrients.2020; 12(1): 189. CrossRef
Level of Blood Lead and Urine Cotinine of Residents by Area
Yu-Jin Oh, Hyoung-Wook Kim, Yun-Jae Kim, Yoon-Deok Han, Sung-Hyeon Jung, Jong-Dae Lee, Bong-Ki Jang, Jin-Heon Lee, Bu-Soon Son
Journal of Environmental Science International.2019; 28(3): 329. CrossRef
A Review for the Long-Term Trend and Spatial Distribution of Soil Mercury Concentration in South Korea
Pyung-Rae Kim, Dae-Young Kim, Young-Ji Han
Journal of Korean Society of Environmental Engineers.2019; 41(6): 346. CrossRef
An analysis of factors affecting the mercury content in the human femoral bone
A. Zioła-Frankowska, M. Dąbrowski, Ł. Kubaszewski, P. Rogala, A. Kowalski, M. Frankowski
Environmental Science and Pollution Research.2017; 24(1): 547. CrossRef
The associations between blood mercury levels and shark meat intake among workers in Gyeongsangbuk-do
Gun Il Park, Young Seok Byun, Man Joong Jeon, Joon Sakong
Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef
A Study on Mercury Exposure Levels among Schoolchildren and Related Factors in High Mercury Exposure Areas in Korea
Dae Seon Kim, Young Min Kwon, Hee-Ung Chung, Sang Hoon Nam, Seung Do Yu
Korean Journal of Environmental Health Sciences.2015; 41(4): 231. CrossRef
Mercury Exposure Factors among Residents in the Highly Mercury Exposed Area, Seoksan-ri, Korea
Dae Seon KIM, Young Min Kwon, Hee-Ung Chung, Kyunghee CHOI
Korean Journal of Environmental Health Sciences.2015; 41(5): 349. CrossRef
Population correlates of circulating mercury levels in Korean adults: the Korea National Health and Nutrition Examination Survey IV
Seongbeom Cho, David R Jacobs, Kyong Park
BMC Public Health.2014;[Epub] CrossRef
A Study on Concentrations of Heavy Metal in Blood and Urine of Local Area in Korea
Ji-Young Im, Eun-Kyung Chung, Hee-Jin Park, Seungdo Yu, Bong-Ki Jang, Bu-Soon Son
Journal of Environmental Science International.2013; 22(1): 59. CrossRef
The Relationships Between Blood Mercury Concentration and Body Composition Measures Using 2010 Korean National Health and Nutrition Examination Survey
Dae-won Kang, Ka-young Lee
The Korean Journal of Obesity.2013; 22(4): 237. CrossRef
The Relationship between Fish Consumption and Blood Mercury Levels in Residents of Busan Metropolitan City and Gyeongnam Province
Chan Woo Kim, Young Wook Kim, Chang Ho Chae, Jun Seok Son, Ja Hyeon Kim, Hyoung Ouk Park, Yune-Sik Kang, Jang-Rak Kim, Young Seoub Hong, Dae-Seon Kim, Baek Geun Jeong
Journal of agricultural medicine and community health.2012; 37(4): 223. CrossRef
The Influence of Fish Consumption on Umbilical Cord Blood Mercury Level in Pregnant Women in the City of Tongyeong, Korea
Chul-Won Jang, Sang-Hyun Kim, Jong-Duck Choi
Journal of Food Hygiene and Safety.2012; 27(1): 74. CrossRef
Developing a Questionnaire to Assess Exposure to Food-Borne Hazards
Sangah Shin, Seul Ki Choi, Hyemi Kim, Kyung Youn Lee, Sanghee Shin, Jung Won Lee, Soo Hyun Yu, Hye-Soen Nam, Hae-Jung Yoon, Hyojee Joung
The Korean Journal of Nutrition.2011; 44(1): 61. CrossRef
Blood Heavy Metal Concentrations of Korean Adults by Seafood Consumption Frequency: Using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008
Young A Kim, Young-Nam Kim, Kyung-Dong Cho, Mi Young Kim, Eun Jin Kim, Ok-Hee Baek, Bog-Hieu Lee
The Korean Journal of Nutrition.2011; 44(6): 518. CrossRef
Total and methyl mercury in maternal and cord blood of pregnant women in Korea
Dae Seon Kim, Geun Bae Kim, Tackshin Kang, Seungchul Ahn
Toxicology and Environmental Health Sciences.2011; 3(4): 254. CrossRef

344 View
0 Download
16 Crossref

Original Article

The Health Effects of Mercury on the Cardiac Autonomic Activity According to the Heart Rate Variability: Sinye Lim, Min Cheol Choi, Kee Ock Joh, Domyung Paek; Korean Journal of Occupational and Environmental Medicine 2008;20(4):302-313. Published online December 31, 2008; DOI: https://doi.org/10.35371/kjoem.2008.20.4.302

Abstract PDF

OBJECTIVES
The effect of mercury on the cardiovascular system has recently been reported on, but the mechanisms as well as its nature of this effect still need to be confirmed. In this study, the mercury in the hair of a community population was analyzed in relation to the cardiac autonomic activity.
METHODS
A hair sample was obtained from the occiput area and the mercury in the hair was analyzed by using a Direct Mercury Analyzer. We measured the cardiovascular risk factors, including total cholesterol, triglyceride, blood pressure, and the body mass index (BMI). Heart rate variability was assessed for 5 minutes, in the time and frequency domain, by using SA-3000P from the Medi-core(R). company. The association between the mercury in the hair and heart rate variability was assessed after controlling for the other cardiovascular risk factors.
RESULTS
The mean age of the 671 total subjects was 36 years. The geometric mean of the hair mercury was 0.90 ppm. The hair mercury level was elevated in males, adults, smokers and drinkers. Hair mercury and age, the systolic and diastolic blood pressure, total cholesterol, triglyceride, LDL cholesterol and BMI were all positively correlated. However, hair mercury and heart rate, HDL cholesterol, standard deviation of the NN intervals (SDNN), total power (TP), low-frequency (LF), high- frequency (HF) were negatively correlated. In the higher mercury group, heart rate, SDNN, LF and HF indices were significantly lower compared with those of the lower mercury group. Heart rate was decreased 2.6 beats/min, Ln (HF) was decreased 0.131 msec2 and HF norm was decreased 2.550 with a 1 ppm increase of Ln (Hg), according to multiple linear regression analysis after controlling for age, gender and other cardiovascular risk factors.
CONCLUSION
This cross-sectional study showed that mercury may affect the cardiac autonomic activity through parasympathetic dysfunction.

Citations

Citations to this article as recorded by

Association between dental amalgam restoration and urine mercury concentrations among young women: a cross-sectional study
Su-Bin Park, Eun-Kyong Kim, Joon Sakong, Eun Young Park
Journal of Yeungnam Medical Science.2023; 40(4): 373. CrossRef
The association between mercury concentrations and lipid profiles in the Korean National Environmental Health Survey (KoNEHS) cycle 3
Soo Ho Sohn, Han Cheol Heo, Seongmin Jo, Chulyong Park, Joon Sakong
Annals of Occupational and Environmental Medicine.2020;[Epub] CrossRef
Mercury and metabolic syndrome: a review of experimental and clinical observations
Alexey A. Tinkov, Olga P. Ajsuvakova, Margarita G. Skalnaya, Elizaveta V. Popova, Anton I. Sinitskii, Olga N. Nemereshina, Evgenia R. Gatiatulina, Alexandr A. Nikonorov, Anatoly V. Skalny
BioMetals.2015; 28(2): 231. CrossRef

277 View
5 Download
3 Crossref

Original Article

Mercury Concentrations of Maternal and Umbilical Cord Blood in Korean Pregnant Women: Preliminary Study: Kyung Eun Lee, Young Seoub Hong, Dae Seon Kim, Myoung Seok Han, Byeng Chul Yu, Young Wook Kim, Mee Sook Roh, Hyun Jae Lee, Jae Won Lee, Jong Young Kwak, Joon Youn Kim; Korean Journal of Occupational and Environmental Medicine 2007;19(4):268-275. Published online December 31, 2007; DOI: https://doi.org/10.35371/kjoem.2007.19.4.268

Abstract PDF

OBJECTIVES
To evaluate the level of maternal and prenatal mercury exposure and to analyze the related factors.
METHODS
Fifty-nine pregnant women were recruited into this study after obtaining informed consent. Samples were collected at delivery from normal pregnant women who were living in the city of Busan, Korea. Mercury concentrations in maternal and umbilical cord blood samples were measured using a gold-amalgam collection method. The total and methyl mercury levels of 36 of the 59 pregnant women were analyzed after randomization, and the results were compared.
RESULTS
The mean total mercury concentration was 3.16+/-1.21 ppb and 5.43+/-2.22 ppb in maternal and cord blood, respectively. The average, maternal blood mercury level was lower than the prescribed toxic limit for human (WHO, 5 ppb), whereas the cord blood mercury was higher. The mercury exposure level exceeded the WHO recommendation in 5 (8.47%) cases of maternal blood and 29 of (49.15%) cord blood. There was a significant correlation between maternal and cord blood mercury concentrations. Total mercury and methyl mercury concentrations of the 36 random pregnant women were 3.06+/-1.17 ppb, and 2.60+/-1.11 ppb in maternal blood, and 5.20+/-2.36 ppb, and 4.70+/-1.97 ppb in cord blood, respectively. Methyl mercury accounted for 85.0% of the total mercury in maternal blood and 90.4% in cord blood. There was a significant correlation between total and methyl mercury concentrations.
CONCLUSIONS
The study results suggest that mercury concentrations of cord blood may be regarded as indicative of high prenatal mercury exposure. Therefore, further studies are necessary to explain the cause of high mercury concentrations in cord blood, and to examine its relationship with various health indices.

Citations

Citations to this article as recorded by

Risk assessment of heavy metals in tuna from Japanese restaurants in the Republic of Korea
Seong-Jin Bae, Kyu-Sik Shin, Chulyong Park, Kiook Baek, So-Young Son, Joon Sakong
Annals of Occupational and Environmental Medicine.2023;[Epub] CrossRef
The Relationship between Mercury Exposure Indices and Dietary Intake of Fish and Shellfish in Women of Childbearing Age
Jeong-wook Seo, Byoung-gwon Kim, Young-seoub Hong
International Journal of Environmental Research and Public Health.2020; 17(13): 4907. CrossRef
Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
Yu-Mi Kim, Jin-Young Chung, Hyun An, Sung Park, Byoung-Gwon Kim, Jong Bae, Myoungseok Han, Yeon Cho, Young-Seoub Hong
International Journal of Environmental Research and Public Health.2015; 12(10): 13482. CrossRef
Correlation Between Total Mercury and Methyl Mercury-In Whole Blood of South Korean
Seon A Jung, Dayoung Chung, Jiwon On, Myeong Hee Moon, Jeongae Lee, Heesoo Pyo
Bulletin of the Korean Chemical Society.2013; 34(4): 1101. CrossRef
The Influence of Fish Consumption on Umbilical Cord Blood Mercury Level in Pregnant Women in the City of Tongyeong, Korea
Chul-Won Jang, Sang-Hyun Kim, Jong-Duck Choi
Journal of Food Hygiene and Safety.2012; 27(1): 74. CrossRef

248 View
0 Download
5 Crossref

Case Report

Subcutaneous and Gastrointestinal Exposure to Metallic Mercury: Report of 2 Cases: Sung Kwan Lee, Hyoung Jai Lee, Hong Jae Chae, Jai Dong Moon; Korean Journal of Occupational and Environmental Medicine 2003;15(4):446-451. Published online December 31, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.4.446

Abstract PDF: BACKGROUND
Mercury poisoning presents a variety of clinical pictures depending on the chemical structure, the route of exposure, the amount absorbed and other individual factors. Therefore, the ingestive and subcutaneous absorption of elemental(metallic) mercury can be considered to be relatively harmless in contrast to the inhalation of mercury vapor.
CASE REPORTS
A 72-year-old man presented to the department of urology due to tenderness, edema and a necrotic abscess of his penis after trauma. The soft tissue abscess required a surgical resection of the penis. For chelation therapy, oral D-penicillamine was administrated. 7 months later, he showed no subjective or objective signs of mercury poisoning. Another 5-yearold girl presented to the emergency department after accidental self-ingestion of elemental mercury. She was followed clinically and did not show any systemic mercury poisoning.
CONCLUSION
The Mercury concentrations in the blood and urine were elevated in the case of subcutaneous exposure, but was unchanged in the case of ingestion. Subcutaneous and gastrointestinal exposure to metallic mercury has a minimal risk for systemic mercury poisoning, which is in contrast to the exposure by inhalation.

138 View
0 Download

Original Article

Effect of Glutathione on Apoptosis Induced by Methyl Mercury Chloride: Jung Ho Youm, Dai Ha Koh, Keun Sang Kwon, Me Yae Lee; Korean Journal of Occupational and Environmental Medicine 2002;14(4):377-391. Published online December 31, 2002; DOI: https://doi.org/10.35371/kjoem.2002.14.4.377

Abstract PDF: OBJECTIVES
This study was performed to evaluate the critical role of glutathione(GSH) in methyl mercury chloride(MeHgCl)induced cell apoptosis.
METHODS
The effect of GSH in MeHgCl induced cell apoptosis was observed in mouse macrophage-derived RAW 264.7 cells in vitro. The cells were cultured in Dulbecco's modified Eagle's medium(DMEM).
RESULTS
MeHgCl exerted a dose dependent cytotoxicity,as demonstrated by the MTT assay, which is an assay dependent partially on the mitochondrial function. Moreover, in the presence of NAC, a GSH precursor, the MeHgCl induced cytotoxicity was significantly decreased whereas BSO, a specific GSH synthesis inhibitor,increased the MeHgCl induced cytotoxicity.The MeHgCl induced DNA fragmentation and chromatin condensation was consistent with the morphological alterations. The MeHgCl treated cells exhibited increasing annexin V-FITC binding to the phos-phatidylserine(PS)translocated from the inner to the outer leaflet of the plasma membrane and those cells with NAC pretreatment significantly exhibited decreasing annexin V-FITC binding compared to the cells treated with MeHgCl only. However BSO pretreatment markedly exhibited the increasing annexin V-FITC binding. The MeHgCl treated cells generated ROS, which was evidenced by the oxidation of dihydroethidine and the generation of the fluorescent product, ethidium. In addition, BSO pretreatment further enhanced the extent of ROS generation caused by MeHgCl whereas NAC pretreatment decreased the amount of ROS generation. MeHgCl led to a dose dependent decrease in the GSH content. Although MeHgCl exposure significantly reduced the GSH level, those cells that had a NAC pretreatment contained a higher level of GSH compared to the cells treated with MeHgCl only. In contrast, BSO pretreatment futher enhanced the extent of GSH depletion caused by MeHgCl.
CONCLUSIONS
These results indicate that MeHgCl reduced the GSH content and impaired the defense against oxidative damage caused by ROS formation in RAW 264.7 cells. It is possible that these factors leads to the activation of the apoptosis signaling pathway. Ultimately these results suggest that GSH plays a crucial role in protecting the activity against MeHgCl induced apoptosis.

178 View
1 Download

Original Article

Concentration of Lead, Cadmium, and Mercury in Scalp Hair, Cerebellum, Cerebrum, Heart, Kidney, Liver, Lung and Spleen from Autopsy Subjects : Relationship between Scalp Hair and Internal Organs: Jong Hak Chung, Chang Yoon Kim, Joon Sakong, Joong Jung Lee, Man Joong Jeon, Seong Kuk Lee, Jeung Sik Kwak, Sung Hwa Park; Korean Journal of Occupational and Environmental Medicine 1998;10(4):571-586. Published online December 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.4.571

Abstract PDF

This study was conducted to measure the lead, cadmium and mercury levels in the scalp hair, cerebellum, cerebrum, heart, kidney, liver, lung, and spleen of the 60 Korean autopsy subjects and assess the relationship among those samples. The mean lead level in the scalp hair was 12.29+/-12.51 microgram/g and no significant difference was detected in lead concentrations between the two sexes. Among the internal organ tissues the cerebrum contained the highest level of lead. This is followed by the cerebellum, spleen and liver respectively. After which the kidney and lung showed a close similarity at relatively low concentrations and the heart contained the lowest concentration. There was also no significant variation found between sexes in a comparison of lead in the internal organ tissues. The concentrations of cadmium in kidney were 127.33+/-89.36 microgram/g and considerably higher than those in the other internal organs. The liver contained the next highest level of cadmium. In both sexes, the consistent difference was noted in the cadmium concentrations of the kidney, heart and spleen. Yet female cadmium level was higher than the male's. The concentrations of mercury in the kidney and liver were 1.26+/-2.89 microgram/g, 0.59+/-0.54 microgram/g and considerably higher than those in the other internal organs. The mean mercury level in the scalp hair was 1.29+/-0.64 microgram/g and no marked difference was noted in both sexes. The lead concentration in the spleen increased with advancing age, though not statistically significance, and most of the internal organ tissues that were examined showed no evidence of increased lead concentration with age. The kidney, cerebrum, spleen and cerebellum showed increased cadmium concentrations with age. Also as well as the internal organ tissues that were examined showed no evidence of increased mercury concentration with age. The lead concentrations in the liver and lung were higher in the urban area than in the rural area, but the lead concentration in the kidney was higher in the rural area. No difference was noted in tissue cadmium and mercury concentrations as to the area of residence either. The physical workers had greater concentrations of lead in cerebellum than did housewives or the unemployed. Yet no difference was noted in the other tissues between the two groups. In the cerebellum, cerebrum, heart, and spleen, the physical workers had greater concentrations of cadmium than students or mental workers. Also physical workers had greater concentrations of cadmium in lung than housewives or the unemployed. In contrast to lead and cadmium, both the housewives and the unemployed had higher concentrations of mercury in cerebellum and cerebrum than physical workers, but there was no difference was noted in the other tissues between the two groups. In the lead concentration, there was no statistically significant correlation between the scalp hair and examined internal organ tissues. There was a close relationship between lead levels in cerebellum and cerebrum (r=0.465, p<0.01), as well as a relationship between the cerebellum and the kidney(r=0.300, p<0.05). There was no statistically significant correlation between the cadmium levels in the scalp hair and in the examined internal organ tissues. Positive correlations were found between the cadmium concentrations in the cerebellum and the cerebrum(r=0.5543, p<0.01), heart(r=0.480, p<0.01), kidney(r=0.376, p<0.01) and spleen(r=0.408, p<0.01). Also positive correlation was found between in the cerebrum and the heart(r=0.377, p<0.01), kidney(r=0.484, p<0.01), liver(r=0.265, p<0.05), lung(r=0.458, p<0.01) and spleen (r=0.483, p<0.01). There was also no statistically significant correlation between the mercury levels in the scalp hair and in the examined internal organ tissues. Positive correlation was found between the mercury concentrations in the cerebellum and cerebrum(r=0.760, p<0.01), heart(r=0.270, p<0.05), liver(r=0.425, p<0.01), lung (r=0.488, p<0.01) and spleen (r=0.534, p<0.01), and also positive correlation was found between in the cerebrum and heart(r=0.376, p<0.01), liver(r=0.350, p<0.01), lung(r=0.554, p<0.01) and spleen (r=0.489, p<0.01). Various epidemiological studies reported usefulness and reliability of using scalp hair as a monitor of a environmental pollutants. In this study, there was statistically significant correlation of lead, cadmium and mercury levels in most of the tissues that were examined, but there was no statistically significant correlation between the lead, cadmium and mercury levels in the scalp hair and most of examined internal organ tissues. The findings of this study would suggest that it is still uncertain to using scalp hair as a biological monitoring.

Citations

Citations to this article as recorded by

Human Exposure to Metals: Levels in Autopsy Tissues of Individuals Living Near a Hazardous Waste Incinerator
Montse Mari, Martí Nadal, Marta Schuhmacher, Eneko Barbería, Francisco García, José L. Domingo
Biological Trace Element Research.2014; 159(1-3): 15. CrossRef
Effect of metallothionein core promoter region polymorphism on cadmium, zinc and copper levels in autopsy kidney tissues from a Turkish population
Zeliha Kayaaltı, Görkem Mergen, Tülin Söylemezoğlu
Toxicology and Applied Pharmacology.2010; 245(2): 252. CrossRef

243 View
0 Download
2 Crossref

Original Article

Effects of the Chelating Agent on the Nephrotoxicity and Histopathological Change in Rat after Administration of Inorganic Mercury: Bong Suk Cha, Sang Baek Koh, Soon Won Hong; Korean Journal of Occupational and Environmental Medicine 1997;9(2):292-300. Published online June 30, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.2.292

Abstract PDF: This study was to determine the effects of Sodium-N-[4-methoxybenzyl]-D-glucamine-N-dithiocarbamate(MeOBGDTC) on the nephrotoxicity of mercury and histopathological change in rats pretreated with mercuric chloride 48h earlier. In a firsts experiment, 3 groups were given a single injection i.p. of 3.5 micromol/kg of HgCl2 mixed with 1microCi of 203Hg2+ in a final volume of 0.5ml of physiologic saline. Subsequently the rats also received the chelator, 1 mmol/kg of MeOBGDTC, at 1h in group 2 (HgCl2-MeOBGDTC 1h) and 12h in group 3 (HgCl2-MeOBGDTC 12h) after injection of mercuric chloride. The results showed that the injection of chelating agent at 1h after mercury injection significantly decreased mercury level in plasma. But not significant in renal cortex. In a second experiment, rats were divided into 4 groups, one group was control group, others were mercury injected group. MeOBGDTC was also administered to mercury-injected rats as described above. The changes in renal function were determined by measurement of proteinuria, plasma creatinine and urinary osmolality. The results showed that the injection of mercuric chloride increased the excretion of urinary protein and plasma creatinine, and decreased the urinary osmolarity. However, the injection of chelating agent at 1h after mercury injection significantly decreases the toxic effects of mercury. Finally, histopathological change at the light microscopic level was comparable effect of chelating agent on nephrotoxicity of mercury. Minimal morphological alterations were seen in kidney of rats of HgCl2-MeOBGDTC 1h. The HgCl2-MeOBGDTC 12h caused necrotic change of the proximal tubule at cortical-medullary junction. These changes were more common and more severe at the HgCl2 alone.

172 View
0 Download

Original Article

A Study on Factors Related to NO Synthesis by Mercurial Compounds in the EMT-6 cell: Jung Ho Youm; Korean Journal of Occupational and Environmental Medicine 1997;9(1):122-130. Published online February 28, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.1.122

Abstract PDF: The effects of several factors on the nitrite synthesis were observed in the culture of EMT-6 cells which are originated from mammary adenocarcinoma of Balb/c mouse. The cells were cultured in Dulbecco's Modified Eagle's Medium containing 10% fetal calf serum. Amounts of nitrite in the culture media after 24 and 36 hours of culture were about 2 fold, and 3-fold of those measured after 12 hours respectively. There were very close associations between the amounts of nitrite measured in the culture media. A significant nitrite synthesis by EMT-6 cells occurred when IL-1 was added to the culture medium with other cytokines as IFN gamma or TNF alpha . One of each cytokines were less effective as an inducer of nitrite than the combinations of cytokines. When mercury chloride or cinnamate was added in the culture medium, the nitrite synthesis was dose-dependently decreased by the concentration of these materials. The viability of EMT-6 cells were kept on 95% or above in 36 hours after beginning of culture without any specific additives except cytokines. While after 48 hours it went down to 85% or less. These viability were decreased by the prolongation of culture time (48 hours or more), the addition of TNF alpha to cytokine mixture, and the higher concentrations of mercury chloride or cinnamate to culture medium. Simultaneous addition of the equimolar dose of selenium completely prevented mercurial compounds-induced inhibitions of nitrite syntheses. But the single addition of selenium neither influenced the viability of cells nor the productions of nitrite. These results suggests that the disorder of cell mediated immunity by mercurial compounds could be related to the inhibition of nitric oxide synthesis and selenium decreased the cytotoxicity of mercurial compounds.

135 View
0 Download

Original Article

A Study of Cytotoxical Mechanism of Mercurial Compounds in RAW264.7 Cell Line: Kong Ho Kirn, Byoung Yul Soh, Dai Ha Koh; Korean Journal of Occupational and Environmental Medicine 1996;8(3):560-569. Published online December 31, 1996; DOI: https://doi.org/10.35371/kjoem.1996.8.3.560

Abstract PDF: The effects of glucose on the productions of ATP and nitrite which are inhibited by mercury compounds, were examined in a cell culture system of RAW 264.7 cells. The cells were cultured in Dulbecco's Modified Eagle's medium (DMEM) with cytokines, IL-1 and TNF for 24 hours. The viablility of RAW 264.7 cells at the end of culture was significantly decreased by mercury chloride or methylmercury chloride added into the media in dose-dependent manner, however the viability of RAW 264.7 cells were influenced in the concentrations lese than 0.8micrometer of mercury chloride or 0.4micrometer of methylmercury chloride. The addition of 4.5 g/l glucose to normal DMEM lowered the pH of media to the range of 6.7-6.8 after 48 hours of culture, but not for the cell survivals. This supplement of glucose to the media also prevented the inhibitions of ATP and nitrite syntheses which were caused by mercurial compounds. These results suggest that the disorder of cell mediated immunity by mercurials could be related to the inhibition of nitric oxide synthesis which seams to be caused by the inhibition of ATP synthesis, especially related to the citric acid cycle.

168 View
0 Download

Original Article

Effect of Mercury Chloride on Peritoneal Macrophage or EMT-6 cell from Balb/c mice: Dai Ha Koh, Jung Ho Youm, No Suk Ki, Gyung Jae Oh, Kuen Sang Kwon, Sung Yeup Kim, Nam Song Kim; Korean Journal of Occupational and Environmental Medicine 1996;8(2):201-209. Published online September 30, 1996; DOI: https://doi.org/10.35371/kjoem.1996.8.2.201

Abstract PDF: The effect of treatment of mercury chloride on the nitrite and nitrate synthesis was observed in peritoneal macrophages from Balb/c mice and EMT-6 cells in vitro. The cells were cultured in Dulbecco's modified Eagle's medium (DMEM) with cytokines. Amounts of nitrite and nitrate in the culture media after 24 and 36 hours of culture were about 2-fold, and 3-fold of those measured after 12 hours respectively. There were very close associations between the amounts of nitrite and nitrate measured in the culture media, according to culture time. The survival rate of peritoneal macrophages was significantly decreased by mercury chloride added into the media in dose-dependent manner, however the survivals of EMT-6 cells were not influenced by mercury chloride concentration in media. Nitrite and nitrate syntheses were dose-dependently decreased by mercury chloride added in culture media. These results reported here suggest that the disorder of cell mediated immunity by mercurials could be related to the inhibition of nitric oxide synthesis which seems to be caused by the inhibition of metabolism of cells.

149 View
0 Download

Original Article

Evaluation of Mercury Concentration in Spot Urine for Biological Monitoring Among Metallic Mercury Exposed Workers: Durumee Hong, Soon Duck Kim, Yong Tae Yum, Jae Wook Choi; Korean Journal of Occupational and Environmental Medicine 1996;8(1):127-136. Published online February 29, 1996; DOI: https://doi.org/10.35371/kjoem.1996.8.1.127

Abstract PDF: Biological monitoring for exposures permits estimation of organ doses or body burdens from exposures through all relevant portals of entry. Biological monitoring data may be used to estimate environmental concentrations when the latter cannot be measured directly. Biological indices are usually surrogates for the concentration of a chemical or its metabolites or its effect at the true receptors. Mercury concentration in urine has-been most-coinmoialy-recommended as a biological exposure index of mercury. For data based on urine analysis, variation in urine volume is the most significant. The urinary concentration related to excretion of the solute provides some correction for fluctuation of urine output. Sampling time must be carefully observed because distribution and elimination of a chemical are kinetic events. This study has evaluated mercury concentration in spot urine compared to the results of 24 hour collected urine by the adjustment methods (specif ic gravity, creatinine) and sampling time. The subjects were 43 workers who had been exposed to the metallic mercury. The results were as follows: 1. The correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were 0.639-0.715 and were not different by adjustment methods. 2. In the high exposure group who were over lOOug/1 of urinary mercury, the correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were 0. 687-0.824 and were not different by adjustment methods. 3. Mercury concentration in spot urine were very variable by sampling time or exposure time. The correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were most highest as 0.85-0.91 at first voiding urine in the morning, and were 0. 77-0.86 at urine collected within four hours before end of shift. In the biological monitoring to exposure of mercury, sampling of spot urine were most proper at first voiding urine in the morning, and then at urine collected within four hours before end of shift. But the adjustment methods of specific gravity and creatinine were no difference of the results.

149 View
0 Download

Original Article

Mercury Concentration in air and in Urine of Workers in Fluorescent Lamp Manufacturing Factories in Korea: Kwang Jong Kim, Chul Whan Cha; Korean Journal of Occupational and Environmental Medicine 1990;2(2):179-185. Published online August 31, 1990; DOI: https://doi.org/10.35371/kjoem.1990.2.2.179

Abstract PDF: This research was conducted to investigate the correlations between urinary mercury concentration and each independent variable related with urinary mercury levels. the urinary mercury concentrations of 543 workers exposed to metal mercury vapor in a total of 11 fluorescent lamp manufacturing factories and at the same time mercury concentrations in air were measured from June 1989 to December 1989. And annually mercury consumption per workers, mercury consumption per lamp, numbers of breakage lamps, frequency of mercury infusion, numbers of droppers, and numbers of vacuum exhaustion pumps were also investigated. The results were as follows: 1. The geometric mean of airborne mercury concentration in a total of 11 factories was 47.9 microgram/m3 (5.8~352.2 microgram/m3), six factories(54.5%) of them were exceed the threshold limit value(50.0 microgram/m3). 2. The geometric mean of urinary mercury concentration among 543 workers was 84.3 microgram/l (1.13~533.9 microgram/l), the distribution of workers by urinary mercury concentration showed that 26 workers(4.8%) were above the mercury posioning level(300 microgram/l). 3. The correlation coefficient between urinary mercury concentration and monthly numbers of breakage lamps was the highest(0.74) and next was mercury consumption per lamp (0.67), annually mercury consumption per worker(0.63) in order.

131 View
0 Download

Original Article

An Investigation of Mercury Contamination Soures in Fluorescent Lamp Manufacturing Industries in Korea: Chang Joo Lee, Kwang Jong Kim, Chul whan Cha; Korean Journal of Occupational and Environmental Medicine 1990;2(1):58-63. Published online February 28, 1990; DOI: https://doi.org/10.35371/kjoem.1990.2.1.58

Abstract PDF: This research was conducted to study the correlations between the airborne mercury concentration and each independent variable to detect the source of mercury contamination in a total or II fluorescent lamp manufacturing factories- The mercury concentraion in air was measured and informations about production management (operation hour, overtime, vacuum exhaustion system, number of droppers, number of vacuum exhaustion pumps, frequency of mercury infusion, mercury consumption per lamp, number of lamps producted, number of inferior lamps producted, number of breakage lamps, local exhaust ventilation system) were collected from January 1988 to March 1989. The results were as follows: 1. Among the airborne mercury concentrations according to the sampling point the highest mean concentration was 0.162mg/m3(0.016-0.635 mg/m3) at the workplace floor, and 0.074 mg/m3 at the vaccum exhaustion pump site, and 0.06 mg/m3 at the breathing zone in order. 2. The correlation between airborne mercury concentration and each Independent variable was significant in a following order; the number of Inferior lamps productedt(0.485), vacuum exhaustion syatem(-0,405), number of breakage lamps (0.344), operation hourl(0.341), number of vacuum exhaustion pumps(0.337) and local exhaust ventilation systern(0.331). 3. The result of stepwise multiple regression analysis showed that the airborne mercury consumption was affected by number of inferior lamps producted, frequency of mercury infusion, overtime, ventilator, mercury consumption amounts per lamp, local exhaust ventilation system in order. And these six variables explained 36.7% of the variance of airborne mercury concentration.

161 View
0 Download

Original Article

Mercury Concentration in Air and in Urine of Workers in A Fluorescent Lamp Manufacturing Factory: Seung Hoi Park, Kwang Jong Kim, Soung Hoon Chang, Chul Whan Cha; Korean Journal of Occupational and Environmental Medicine 1989;1(2):197-205. Published online November 30, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.2.197

Abstract PDF: In order In interpret the relationship among many variables, urinary mercury and at the same time mercury concentration in air were measured for 254 workers of a fluorescent lamp manufacturing factory. And monthly mercury consumption amounts, numbers of monthly producing fluorescent lamps, numbers of inferior lamps and numbers of breakage lamps, numbers of vacuum exhaustion pumps and frequencies of mercury infusion were also investigated from January 1988 to March in 1989. The results were as follows; 1. On the mercury concentration in air by producing line and by working site, all of them were exceed the threshold limit value (0.05mg/m(2)). 2. The highest mercury concentration in air by sampling point was found at the floor of workplace (0.334mg/m(2)) and next were at vacuum exhaustion pimp (0.183mg/m(2)), and breathing zone of workers (0.103mg/m(2)) in order. 3. The highest mean of the mercury concentration in urine by producing line was the automatic exhausting line (80.8microgram/1) and next were high speed exhausting line (72.4microgram/1), and Manual exhausting line (35.8microgram/1) in order. Distribution of workers of the mercury concentration in urine more than 200microgram/1 by working site was the highest (10%) in the vacuum exhaustion pump part and next were sealing part (6.6%), packing part (4.6%), and stem part (4.1%) in order. 4. The correlation coefficient between mercury concentration in urine and in air was the highest (0.302) and next were numbers of breakage lamps (0.223), frequencies of mercury infusion (0.223), numbers of inferior lamps (0.205) in order.

132 View
0 Download

First
Prev
Page of 1
Next
Last

Search