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Original Article
Relationship between shellfish consumption and urinary phthalate metabolites: Korean National Environmental Health Survey (KoNEHS) cycle 3 (2015-2017)
Jisoo Kang, Seong-yong Cho, Jinseok Kim, Seongyong Yoon, Jong-min An, Gayoung Kim, Si young Kim
Ann Occup Environ Med 2023;35:e2.   Published online February 6, 2023
DOI: https://doi.org/10.35371/aoem.2023.35.e2
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Phthalates are endocrine disrupting chemicals that are widely used in the production of items of daily life such as in polyvinylchloride plastics, insecticides, and medical devices. This study aimed to determine the association between phthalate exposure and shellfish consumption using data from the Korean National Environmental Health Survey (KoNEHS) cycle 3 (2015–2017), which is a nationally representative survey.

Methods

In this study, we analyzed the KoNEHS cycle 3 data of 3,333 (1,526 men and 1,807 women) adults aged more than 19 years. Data related to the variables of sociodemographic factors, health-related behaviors, dietary factors, seafood consumption frequency, and urinary phthalate metabolites concentrations were collected. The concentrations of urinary phthalate metabolites of all the participants were divided into quartiles to define high and low concentration groups based on the 75th percentile concentration. A χ2 test was conducted to analyze the distribution of independent variables. To analyze the relationship between shellfish consumption and phthalate exposure, the odds ratios (ORs) were calculated using logistic regression analysis.

Results

Total adults with shellfish consumption frequency of over once a week showed the following adjusted ORs for high concentrations of the following metabolites compared with the group that consumed shellfish once a week or less: 1.43 (95% confidence interval [CI]: 1.01–2.06) for mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP), 1.43 (95% CI: 1.01–2.03) for mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP), 1.57 (95% CI: 1.10–2.24) for ∑di-2-ethylhexyl phthalate (∑DEHP), 2.01 (95% CI: 1.46–2.77) for mono-carboxyoctyl phthalate (MCOP), 1.56 (95% CI: 1.11–2.18) for mono-carboxy-isononly phthalate (MCNP), and 2.57 (95% CI: 1.85–3.56) for mono (3-carboxypropyl) phthalate (MCPP).

Conclusions

The concentrations of urinary phthalate metabolites (MEOHP, MECPP, ∑DEHP, MCOP, MCNP, and MCPP) were higher in adults with a higher frequency of shellfish consumption.

국민환경보건 기초조사 제3기(2015-2017) 자료를 이용한 조개류 섭취와 요중 프탈레이트 대사체간의 관계
목적
프탈레이트(phthalate)는 내분비계 장애물질(endocrine disrupting chemicals, EDCs)로서, 일상생활에서 가소제, 살충제, 의료기기 등으로 광범위하게 사용되고 있다. 프탈레이트는 해양 생태계에서 널리 발견되며, 조개류는 해양생태계오염의 대표적인 지표로 사용된다. 현재까지 해양 생태계의 프탈레이트의 오염에 대한 다양한 연구가 수행되고 있으나 국내에서 프탈레이트 노출과 조개류 섭취와 관련된 연구는 아직 이루어진 바가 없다. 따라서 본 연구에서는 우리나라 인구를 대표하는 자료인 국민환경보건 기초조사 제3기(2015-2017) 자료를 이용하여 요중 프탈레이트 대사체와 조개류 섭취와의 연관성을 분석하고자 했다.
방법
본 연구는 국민환경보건 기초조사 제3기(2015-2017) 자료를 이용하여 만 19세 이상 성인 3,333명(남자1,526명과 여자1,807명)을 대상으로 진행하였다. 사회인구학적 변수 및 건강행태 관련 변수 및 식이 요인과 해산물의 섭취 빈도, 요중 프탈레이트 대사체 농도를 변수로 두어 각 변수 간의 분포 차이를 분석하였다. 로지스틱 회귀분석을 사용하여 조개류 섭취빈도에 따라 요중 프탈레이트 대사체 고농도군에 속할 OR값을 계산하였다.
결과
조개류 섭취의 경우 주 1회 초과군에서 MEOHP의 고농도군에 해당될 adjusted ORs은 1.43(95%CI: 1.01-2.06), MECPP 1.43(95%CI: 1.01-2.03), ∑DEHP 1.57(95%CI: 1.10-2.24), MCOP 2.01(95%CI: 1.46-2.77), MCNP 1.56(95%CI: 1.11-2.18), MCPP 2.57(95%CI: 1.85-3.56)으로 조사되었다.
결론
성인에서 조개류 섭취 빈도가 많을수록 요중 프탈레이트 대사체(MEOHP, MECPP, ∑DEHP, MCOP, MCNP, MCPP) 농도가 높았다.

Citations

Citations to this article as recorded by  
  • Urinary phthalate metabolites and heart rate variability: A panel study
    Ziqian Zhang, Miao Liu, Lei Zhao, Linlin Liu, Wenting Guo, Jie Yu, Huihua Yang, Xuefeng Lai, Xiaomin Zhang, Liangle Yang
    Environmental Pollution.2023; 330: 121760.     CrossRef
  • Microplastics induced inflammation and apoptosis via ferroptosis and the NF-κB pathway in carp
    Tianchao Xu, Jie Cui, Ran Xu, Jingwen Cao, Meng-yao Guo
    Aquatic Toxicology.2023; 262: 106659.     CrossRef
  • Relationship between the use of plastics in refrigerator food storage and urine phthalate metabolites: the Korean National Environmental Health Survey (KoNEHS) cycle 3
    Jisoo Kang, Seong-yong Cho, Seongyong Yoon
    Annals of Occupational and Environmental Medicine.2023;[Epub]     CrossRef
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Case Report
Electrocardiogram abnormalities in antimony exposed workers in the automotive brake lining manufacturing industry: a case report
Ha-ram Jo, Seongyong Yoon, Jinseok Kim, Seong-yong Cho, Jong-min An, Gayoung Kim
Ann Occup Environ Med 2022;34:e16.   Published online June 27, 2022
DOI: https://doi.org/10.35371/aoem.2022.34.e16
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Antimony is used in catalysts, pesticides, brake systems, pharmaceuticals, and synthetic fire retardants in the plastic, paint, and rubber industries. Accumulation of trivalent antimony compounds in the body can cause cardiotoxic effects and increase the risk of electrocardiogram (ECG) abnormalities and sudden death. Antimony exposure can result in action potential prolongation, causing a cardiac repolarization delay, which appears as QTc prolongation and T-wave abnormalities on the ECG. There are no studies on antimony-associated cardiac toxicity in Korea.

Case presentation

Accordingly, the present study reports cases of ECG abnormalities in workers handling antimony trisulfide at a company located in the Gyeongsangbuk-do region. Nineteen workers employed at an automobile brake lining manufacturer were exposed to antimony trisulfide dust through thermoforming, grinding, and drilling processes. In 2020, the workers were reported to work 12-hour shifts, 5 days a week. The time-weighted average (TWA) of antimony trisulfide exposure measured in workers was 0.0028 mg/m3. Two workers were excluded from the analysis due to pre-existing medical conditions (cardiovascular disease). Of the remaining 17 workers, ECG abnormalities were found in 41% (seven out of 17: four with QTc prolongation and T-wave abnormalities; two with only T-wave abnormalities; and one with only QTc prolongation).

Conclusions

This case report outlines the first few cases in Korea in which potential cardiac toxicity caused by occupational exposure to antimony was identified. However, data regarding cardiac toxicity caused by antimony exposure are still lacking in Korea; thus, additional studies are needed to identify causal relationships.

자동차 브레이크 라이닝 제조업에 근무하는 안티몬 노출 근로자의 심전도 이상: 사례 보고서
배경
안티몬은 촉매, 살충제, 브레이크 시스템 및 의약품에 사용되며 플라스틱, 페인트 및 고무 산업에서 합성 난연제로 사용된다. 3가 안티몬 화합물이 체내에 축적되면 심장 독성 효과를 일으켜 심전도(ECG) 이상 및 급사의 위험이 증가할 수 있다. 3가 안티몬 화합물의 직업적 노출은 활동 전위 연장을 일으켜 심장 재분극 지연을 유발할 수 있으며, 이는 QTc 연장과 T파 이상으로 나타난다. 아직 국내에서는 3가 안티몬 화합물 노출과 관련된 심장 독성에 관한 연구는 없다. 이에 본 연구에서는 경상북도 지역에 위치한 회사에서 삼황화 안티몬을 취급하는 작업자의 심전도 이상 사례를 보고한다.
증례
자동차 브레이크 라이닝 제조업체에 고용된 19명의 작업자가 열성형, 연삭 및 드릴링 공정을 통해 삼황화 안티몬 분진에 노출되어 왔다. 2020년에 삼황화 안티몬에 노출 공정 근로자 19명은 주 5일 12시간 교대로 근무하였다. 근로자에게서 측정한 삼황화 안티몬 노출의 시간 가중 평균(TWA)은 0.0028 mg/m3였다. 2명의 근로자는 심장질환 과거력으로 인해 분석에서 제외되었다. 나머지 17명의 작업자 중 41%에서 ECG 이상이 발견되었다(17명 중 7명의 작업자: QTc 연장 및 T 파 이상 4명, T 파 이상 2명, QTc 연장 1명).
고찰
이 증례 보고서는 국내 최초로 직업상 안티몬 노출로 인한 잠재적인 심장 독성이 확인된 증례에 관해 설명한다. 그러나 우리나라에서는 안티몬 노출에 의한 심장 독성에 대한 자료가 아직 부족한 실정이다. 따라서 인과관계를 규명하기 위해서는 추가적인 연구가 필요하다.
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Research Article
Association of work–life balance with occupational injury and work-related musculoskeletal pain among Korean workers
Jong-min An, Jinseok Kim, Seongyong Yoon, Kuck-Hyun Woo, Seong-yong Cho, Kibeom Kim, Ha-ram Jo
Ann Occup Environ Med 2020;32:e20.   Published online June 30, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e20
AbstractAbstract PDFPubReaderePub
Background

The concept of work-life balance (WLB) has become an important issue in workers' health and safety. This study aims to investigate the relationship between WLB and occupational injury and work-related musculoskeletal pain.

Method

The study included 27,383 workers who participated in the Fifth Korean Working Conditions Survey. Participants were divided into good WLB and poor WLB groups based on their responses to the five question items which comprised two dimensions: work-on-life conflict (items, 1–3) and life-on-work conflict (items 4 and 5). Occupational injury and musculoskeletal pain were also assessed using the question items. The χ2 test and multivariate logistic regression analyses were performed to examine the relationship of WLB to occupational injury and musculoskeletal pain while considering socio-demographic and occupational characteristics and ergonomic and psychological risk factors.

Results

Of the 27,383 participants, 252 (0.9%) had experienced an occupational injury and 6,408 (23.4%) had musculoskeletal pain. The poor WLB group had higher injury rates for both men (1.7%) and women (0.9%) than the good WLB group (1.1% and 0.4%, respectively). Additionally, the prevalence of musculoskeletal pain was higher for both men and women in the poor WLB group (25.2% and 28.0%, respectively) than for men and women in the good WLB group (18.7% and 23.6%, respectively). In the logistic regression analysis, the adjusted odds ratio of WLB for occupational injury was 1.37 (95% confidence interval [CI]: 1.06–1.78), and that for musculoskeletal pain was 1.14 (95% CI: 1.07–1.21), showing positive associations of WLB with both occupational injury and musculoskeletal pain.

Conclusions

Poor WLB causes an increase in occupational injury and musculoskeletal pain. Therefore, an improvement in WLB may reduce the incidence of occupational injury and musculoskeletal pain among workers. Social and policy-related initiatives are needed to improve workers' WLB to reduce occupational injury and musculoskeletal pain.


Citations

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  • Construction and validation of a musculoskeletal disease risk prediction model for underground coal miners
    Haili Zhao, Hong Dou, Xianting Yong, Wei Liu, Saiyidan Yalimaimaiti, Ying Yang, Xiaoqiao Liang, Lili Sun, Jiwen Liu, Li Ning
    Frontiers in Public Health.2023;[Epub]     CrossRef
  • Exploring the relationship between work–family conflict and sleep disturbance: a study on stratification and interaction
    Jian Lee, Juyeon Oh, Heejoo Park, Juho Sim, Jongmin Lee, Yangwook Kim, Byungyoon Yun
    Frontiers in Psychology.2023;[Epub]     CrossRef
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Research Article
Difference in health status of Korean farmers according to gender
Ho Lee, Seong-yong Cho, Jin-seok Kim, Seong-yong Yoon, Bu-il Kim, Jong-min An, Ki-beom Kim
Ann Occup Environ Med 2019;31:7.   Published online March 8, 2019
DOI: https://doi.org/10.1186/s40557-019-0287-7
AbstractAbstract PDFPubReaderePub
Background

The objective of this study was to compare differences in lifestyle diseases, musculoskeletal pain, psychosocial stress, and self-health awareness according to gender in Korean farmers.

Methods

The study population comprised 436 farmers residing in rural areas in Korea. A self-administered questionnaire was used to survey demographic characteristics, health-related behaviors, and musculoskeletal pain. The psychosocial well-being index short form (PWI-SF) was used to survey psychosocial stress, and the 12-item short form health survey (SF-12) was used to survey self-health awareness. In addition, a clinical examination was performed for each participant, and lifestyle diseases were identified through a health checkup.

Results

Among lifestyle diseases, females showed a significantly higher proportion than males for metabolic syndrome (OR: 4.57 [95% CI, 1.67–12.51]). For musculoskeletal pain, females again showed significantly higher proportion than males for hand pain (OR: 16.79 [95% CI, 3.09–91.30]), and pain in at least one body part (OR: 2.34 [95% CI, 1.16–4.70]). For psychosocial stress, females showed a significantly higher proportion than males for high-risk stress (OR: 3.10 [95% CI, 1.17–8.24]). Among the items in self-health awareness, females showed significantly higher proportion than males for mental component score (MCS) (OR: 3.10 [95% CI, 1.52–6.31]) and total score (OR: 2.34 [95% CI, 1.11–4.90]).

Conclusions

For all items that showed significant differences, females showed higher proportion than males, which indicates that female farmers tended to have poorer overall health than male farmers. Therefore, specialized programs will have to be developed to improve the health of female farmers.


Citations

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  • Older Female Farmers and Modeling of Occupational Hazards, Wellbeing, and Sleep-Related Problems on Musculoskeletal Pains
    Dong Seok Shin, Byung Yong Jeong
    International Journal of Environmental Research and Public Health.2022; 19(12): 7274.     CrossRef
  • Autopercepción del Nivel de vida en los asociados a gremios agrícolas en Tungurahua, Ecuador
    Carlos Fabricio Gavilanes Carvajal, Janneth Maricela Illapa Atupaña, María Dolores Guamán Guevara, César Andrés Guerrero Velástegui
    Religación. Revista de Ciencias Sociales y Humanidades.2022; 7(34): e210983.     CrossRef
  • Comparisons of working conditions and health-related problems between older male and female crop farmers
    Byung Yong Jeong
    Work.2022; 72(3): 1025.     CrossRef
  • Key Risk Factors Affecting Farmers’ Mental Health: A Systematic Review
    Sahar Daghagh Yazd, Sarah Ann Wheeler, Alec Zuo
    International Journal of Environmental Research and Public Health.2019; 16(23): 4849.     CrossRef
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Research Article
Factors related with quality on sleep of daytime workers
Bu-il Kim, Seong-yong Yoon, Jin-seok Kim, Kuck-Hyeun Woo, Seong-yong Cho, Ho Lee, Jong-min An
Ann Occup Environ Med 2018;30:63.   Published online October 23, 2018
DOI: https://doi.org/10.1186/s40557-018-0271-7
AbstractAbstract PDFPubReaderePub
Background

This study was conducted to identify the sleep status of daytime workers who do not work in shifts. This study analyzed factors affecting sleep duration and sleep quality.

Methods

This study was conducted on 1171 daytime workers at a manufacturing workshop. We used a self-administered questionnaire to investigate demographic variables, work type, working period, musculoskeletal symptoms and the Pittsburgh Sleep Quality Index to assess sleep. Regular health checkup was conducted for the worker’s clinical examination.

Results

The mean sleep duration was 6.36 h and the mean score on the Pittsburgh Sleep Quality Index was 4.46. Work type and obesity were related to sleep duration. Age, obesity and musculoskeletal pain were significantly related to sleep quality. The prevalence ratio of researcher group for short sleep duration was 1.27 (95% confidence interval: 1.02–1.58). The prevalence ratio of those aged 50 years and over was 0.47 (0.25–0.91) and of those in their 40s was 0.56 (0.35–0.91) for poor sleep quality compared to those in their 20s. The prevalence ratio of the obesity group for poor sleep quality was 1.53 (1.10–2.12). The prevalence ratio of musculoskeletal pain group for poor sleep quality was 1.92 (1.29–2.84).

Conclusions

Age, obesity and musculoskeletal pain were factors affecting the poor quality on sleep of daytime workers. In addition, work type related to short sleep duration.


Citations

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    Revista de Gestão Social e Ambiental.2024; 18(5): e05630.     CrossRef
  • Ağrı Sorunu Olan Ofis Çalışanlarında Yorgunluk, Uyku ve Kavrama Kuvvetinin İncelenmesi: Kontrollü Çalışma
    Ayşenur Baysal Yiğit, Gamze Ekici
    Fenerbahçe Üniversitesi Sağlık Bilimleri Dergisi.2024; 4(2): 230.     CrossRef
  • The Relationship of Musculoskeletal System Disorders with Sleep Quality among Office Workers
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    Genel Tıp Dergisi.2023; 33(3): 316.     CrossRef
  • Vegetarians have an indirect positive effect on sleep quality through depression condition
    Xiaodi Wang, Fangfang Song, Bian Wang, Lei Qu, Zhiping Yu, Xiuhua Shen
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    Ehab Salah Eshak
    Bulletin of the National Research Centre.2022;[Epub]     CrossRef
  • Association of sleep characteristics and respiratory symptoms at a smelting factory
    Mohammad Mehdi Mehrabi Nejad, Arezu Najafi, Abdolkarim Haji Ghadery, Nazanin Izadi, Zahra Banafsheh Alemohammad, Mahya Shabani, Maryam Saraei
    Work.2022; 72(2): 737.     CrossRef
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    Allison Naber, Logan Willhite, Whitney Lucas Molitor
    Work.2021; 68(4): 1133.     CrossRef
  • Poor Sleep Quality and Daytime Sleepiness in Health Professionals: Prevalence and Associated Factors
    Vergílio Pereira Carvalho, Kênia Alves Barcelos, Ely Paula de Oliveira, Sarah Nogueira Marins, Isabella Beatriz Silva Rocha, Daniel Ferreira Moraes de Sousa, Bruno Cabral Moreira, Gunther Abreu de Almeida, Marina Luana Silva Carneiro, Jéssica Duarte de Fr
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  • Sleep quality and health-related quality of life in workers of Kermanshah Industrial Town: A correlation study
    Seyed-Ramin Ghasemi, Mehdi Khezeli, Nader Rajabi-Gilan, Manoochehr Koulani, Nooshin Moloudi-Safa, Ali Hemati, Mojgan Afkari, Fatemeh Zolfaghari
    Indian Journal of Occupational and Environmental Medicine.2020; 24(2): 72.     CrossRef
  • Shift rotation, circadian misalignment and excessive body weight influence psychomotor performance: a prospective and observational study under real life conditions
    Dayane Eusenia Rosa, Luisa Pereira Marot, Marco Túlio de Mello, Fernanda Veruska Narciso, Bruno da Silva Brandão Gonçalves, Elaine Cristina Marqueze, Cibele Aparecida Crispim
    Scientific Reports.2019;[Epub]     CrossRef
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