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- Case Report Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene
- Hong Jae Chae, Seong Kwan Lee, Kang Jin Lee, Jong Youl Kim, Seung Chul Lee, Dong Hyeon Shin, Jai Dong Moon
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Korean Journal of Occupational and Environmental Medicine (대한직업환경의학회지) 2003;15(1):111.
DOI: https://doi.org/10.35371/kjoem.2003.15.1.111
Published online: March 31, 2003
1Department of Occupational and Environmental Medicine, Chonnam National University Hospital, Korea. ajdmoon@chollian.net 
2Department of Dermatology, Chonnam National University Hospital, Korea.
3Department of Internal Medicine, Chonnam National University Hospital, Korea.
2Department of Dermatology, Chonnam National University Hospital, Korea.
3Department of Internal Medicine, Chonnam National University Hospital, Korea.
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Abstract
A 28-year-old male began working as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month the man experienced fever, chills, and an erythematous skin rash and itching. At that time he had a marked elevation in his liver enzyme, with cholestasis. Over the next few days the rash persisted then peeled. There was an elevation of Ig E, and a positive patch test reaction to trichloroethylene. His dermatitis and hepatitis were considered to be mediated by a hypersensitivity mechanism.
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