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- Original Article Assessment of Acquired Color Vision Impairment in Inhalant Abusers
- Myeong Hyo Kim, Yeon Cheol Kim, Kyu Hwa Lee, Man Joong Jeon, Joon Sakong
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DOI: https://doi.org/10.35371/kjoem.2011.23.4.439
Published online: December 31, 2011
1Bugok National Hospital, Korea. 
2Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Korea. jjsakong@gmail.com
3Department of Preventive Medicine and Public Health, College of Medicine, Yeungnam University, Korea.
2Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Korea. jjsakong@gmail.com
3Department of Preventive Medicine and Public Health, College of Medicine, Yeungnam University, Korea.
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Abstract
OBJECTIVES
This study was conducted in order to evaluate the effects of inhalants on color vision impairment.
METHODS
The inhalation group consisted of 81 neurotoxic chemical substance abusers at Bugok National Hospital and Institute of Forensic Psychiatry, Ministry of Justice. The control group consisted of 41 employees of Bugok National Hospital. The Lanthony D-15 desaturated hue test was administered to both groups. For the qualitative analysis, we classified the results by the morphological characteristics of color vision impairment. For the quantitative analysis, we calculated the total color distance score (TCDS) and the color confusion index (CCI) and determined that the individual was abnormal if the TCDS was over 65.0 or the CCI was over 1.25.
RESULTS
The TCDS of the inhalation group was 75.58+/-21.07 and the CCI was 1.34+/-0.37 in the right eye, and 75.47+/-23.63 and 1.34+/-0.42, respectively in the left eye. These results are higher than those found for the control group. In regards to the TCDS, 50 (61.8%) of the abusers in the inhalation group had color vision impairment in the right eye and 48 (59.2%) had impairment in the left eye. 11 (26.8%) of the employees in the control group had color vision impairment in the right eye and 13 (31.7%) had impairment in the left eye. In regards to the CCI, 38 (46.9%) of the abusers in the inhalation group had color vision impairment in the right eye and 35 (43.2%) had impairment in the left eye. 4 (9.8%) of the employees in the control group had color vision impairment in the right eye and 7 (17.0%) had impairment in the left eye. The results of multiple logistic regression analysis for acquired color vision impairment showed that the inhalation period (OR=1.20, 95% CI: 1.03~1.40) was the significant variable.
CONCLUSIONS
These findings indicate that the inhalation of neurotoxic substances may impair the color vision, and the period inhaled with neurotoxic substances is significant variable affecting on the acquired color vision impairment.
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