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- Original Article Sister-Chromatid Exchanges in Lymphocytes of Medical Students Exposed to Formaldehyde
- Soo Jin Lee, Jeong Il Son, Sang Hyo Sim, Kee Young Kim, Jaecheol Song, Suo Ja Chu, Sung Han Shim, Youl Hee Cho, Doo Jin Park
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DOI: https://doi.org/10.35371/kjoem.1998.10.2.282
Published online: May 31, 1998
1Department of Occupational medicine, Hanyang University Hospital, Korea. 
2Department of Medical Genetics, College of Medicine, Hanyang University, Korea.
3Department of Anatomy, College of medicine, Hanyang University, Korea.
4Koryo Industrial Medical Center, Young Nam Medical Foundation, Korea.
2Department of Medical Genetics, College of Medicine, Hanyang University, Korea.
3Department of Anatomy, College of medicine, Hanyang University, Korea.
4Koryo Industrial Medical Center, Young Nam Medical Foundation, Korea.
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Abstract
Sister-chromatic exchanges measured in the peripheral lymphocytes of 15 non-smoking medical students after exposure to formaldehyde during a 24-week anatomy class showed a small but significant (p=0.0468) increase when compared with samples obtained from the same individuals immediately before exposure. Mean frequencies of sister-chromatic exchange of cultured peripheral lymphocytes were 5.40+/-0.24 from the samples before exposure and 5.87+/-0.22 from the same samples after exposure. Breathing-zone air samples collected by formaldehyde monitoring kit with digital colorimeter (SKC) showed a mean concentration of 0.72+/-0.02 ppm formaldehyde.
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