Annals of Occupational and Environmental Medicine

Case Report

A Study on the N-methylformamide Excretion Rate of Workers at Synthetic Leather Factories in Korea: Ki Woong Kim, Byung Soon Choi, Seong Kyu Kang, Young Hahn Moon; Korean Journal of Occupational and Environmental Medicine 1999;11(1):106-112. Published online March 31, 1999; DOI: https://doi.org/10.35371/kjoem.1999.11.1.106

This study was conducted to examine the excretion rate of dimethylformamide (DMF) from the workers exposed to DMF. The study was done at two synthetic leather factories located in Kyeonggi-do from the period of May 2 to 30, 1996. N-methyl- formamide (NMF) concentrations in urine were measured and compared by the three exposure level of DMF in air. The mean concentration of the Low (dry and winder part). Moderate (rinsing part) and High (mixing and coating part) exposure group were 3.99+/-3.54. 10.19 +/-5.69 and 32.10+/-7.87 mg/m3 during workshift of 8 hours, respectively. The mean concentration of urinary N-methylforinamide (NMF) were 2.13+/-2.58, 11.16+/-4.98 and 26.24 +/-7.35 mg/g creatinine, respectively. The concentration of NMIF in urine could reach to maximum in 3 hours and was reduced nearly to zero in about 18 hours after exposure to DMF.

Citations

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Hepatotoxicity in Rats Treated with Dimethylformamide or Toluene or Both
Ki-Woong Kim, Yong Hyun Chung
Toxicological Research.2013; 29(3): 187. CrossRef
Assessment of correlation between markers of ambient monitoring and biological monitoring of dimethylformamide for workers in synthetic leather manufacturing factories in Korea
Yang In Hwang, Mi-Young Lee, Yun Kyung Chung, Eun A Kim
Analytical Science and Technology.2013; 26(5): 315. CrossRef
Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology
Tae Hyun Kim, Sang Geon Kim
Safety and Health at Work.2011; 2(2): 97. CrossRef

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