Annals of Occupational and Environmental Medicine

Original Article

A Study on the Occupational Hazards Associated with Chronic Renal Failure: Kwan Lee, Hyun Sul Lim, Jeong Ho Lee; Korean Journal of Occupational and Environmental Medicine 2004;16(1):25-36. Published online March 31, 2004; DOI: https://doi.org/10.35371/kjoem.2004.16.1.25

Abstract PDF: OBJECTIVE: Recently, chronic renal failure has become a major public health problem all around the world, and the number of patients in Korea affected by this disease has sharply increased since the 1980's. Between 3% and 50% of all cases of chronic renal failure may be induced by toxic agents. The purpose of our study was to investigate the occupational hazards associated with chronic renal failure, in order to use the findings as a reference for further epidemiologic studies.
METHODS
The author conducted a questionnaire and reviewed the medical records of chronic renal failure patients (161 people out of 238) in Gyeongju-si and Pohang-si from March 2 to 31, 2003. Those cases of chronic renal failure which were related to work were classified as either 'probable case' if they were of unknown origin or 'suspected case' if they were of known origin and were related to hypertension or diabetes mellitus.
RESULTS
The study subjects consisted of 92 males (57.1%) and 69 females (42.9%). The causalities listed in the medical records were diabetes mellitus in 55 cases (40.4%), hypertension in 28 cases (20.6%), chronic glomerulonephritis in 14 cases (10.3%), and other diseases. There were 10 cases (6.2%) that were believed to be related to the patients' occupations. The hazards that these 10 patients had previously been exposed to were silica, organic solvents, tin, copper, lead, cadmium, and other hazards.
CONCLUSIONS
Through this study, 10 cases that were reportedly related to occupational chronic renal failure were discovered. Further studies such as a case-control study of occupational risk factors related to chronic renal failure will be needed.

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Original Article

Aluminum Clearance by Hemodialysis in Chronic Renal Failure: Joon Youn Kim, Ki Hyun Kim, Won Suk An, Tae Won Jang, In Sik Kim, Young Seoub Hong, Jung Il Kim; Korean Journal of Occupational and Environmental Medicine 2002;14(1):78-84. Published online March 31, 2002; DOI: https://doi.org/10.35371/kjoem.2002.14.1.78

OBJECTIVES
This study was carried out to investigate aluminum levels in blood and the factors affecting aluminum concentration; we also presented findings on aluminum clearance during hemodialysis in chronic renal failure patients.
METHODS
We selected 56 patients with case of chronic renal failure and 144 healthy examinees as a control group. We analysed aluminum concentrations in their blood, water and dialysis fluid.
RESULTS
The blood aluminum concentration in the 56 patients was 2.38+/-0.27 microgram/ dL , about 4 times higher than that of the control group (p < 0.01). Blood aluminum concentrations were not affected by factors such as creatinine, BUN, hemodialysis duration, iron, and drinking water. After hemodialysis, blood aluminum level were decreased by about 15% and the aluminum concentration in the dialysis fluid was increased.
CONCLUSIONS
Blood aluminum levels were significantly high in the chronic renal failure patients; and hemodialysis helped the patients to excrete aluminum. Authors suggest that a purified dialysis fluid containing a lower aluminum concentration would facilitate aluminum excretion in hemodialysis patients.

Citations

Citations to this article as recorded by

Effects of Lycii fructus Water Extracts of Serum Enzymes Activities on Renin and Aldosterone Hormone in Aluminum Fed Rats
Sung Hee Han
Journal of The Korean Society of Food Culture.2015; 30(4): 468. CrossRef

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