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Aluminum Clearance by Hemodialysis in Chronic Renal Failure
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Original Article Aluminum Clearance by Hemodialysis in Chronic Renal Failure
Joon Youn Kim, Ki Hyun Kim, Won Suk An, Tae Won Jang, In Sik Kim, Young Seoub Hong, Jung Il Kim

DOI: https://doi.org/10.35371/kjoem.2002.14.1.78
Published online: March 31, 2002
1Department of Preventive Medicine, College of Medicine, Dong-A University, Korea. oemroad@dreamwiz.com
2Department of Internal Medicine, College of Medicine, Dong-A University, Korea.
3Department of Occupational Medicine, College of Medicine, Dong-A University, Korea.
4Department of Occupational and Environmental Medicine, Sam-sung Hospital, Yangsan, Korea.
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OBJECTIVES
This study was carried out to investigate aluminum levels in blood and the factors affecting aluminum concentration; we also presented findings on aluminum clearance during hemodialysis in chronic renal failure patients.
METHODS
We selected 56 patients with case of chronic renal failure and 144 healthy examinees as a control group. We analysed aluminum concentrations in their blood, water and dialysis fluid.
RESULTS
The blood aluminum concentration in the 56 patients was 2.38+/-0.27 microgram/ dL , about 4 times higher than that of the control group (p < 0.01). Blood aluminum concentrations were not affected by factors such as creatinine, BUN, hemodialysis duration, iron, and drinking water. After hemodialysis, blood aluminum level were decreased by about 15% and the aluminum concentration in the dialysis fluid was increased.
CONCLUSIONS
Blood aluminum levels were significantly high in the chronic renal failure patients; and hemodialysis helped the patients to excrete aluminum. Authors suggest that a purified dialysis fluid containing a lower aluminum concentration would facilitate aluminum excretion in hemodialysis patients.


Ann Occup Environ Med : Annals of Occupational and Environmental Medicine
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