Annals of Occupational and Environmental Medicine

Original Article

RELATED FACTORS OF DIAGNOSIS OF CHRONIC CARBON DISULFIDE POISONING: Byung Sung Kim, Hyun Rim Choi, Chang Won Won; Korean Journal of Occupational and Environmental Medicine 1997;9(1):1-11. Published online February 28, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.1.1

The purpose of this study was to compare the characteristics between chronic CS2 poisoning group and non-poisoning group, to find out major factors for decision of chronic CS2 poisoning, to describe the characteristics of cerebral infarctions, and to find out the related factors of cerebral infarctions. The study subjects were 220 ex-employees from W company and the study period was from August, 1993 to November, 1995. The proportion rate of chronic CS2 poisoning was higher in older age groups and longer work duration groups. The rate differed by cerebral infarction, microaneurysm, other retina lesions, polyneuropathy, psychiatric lesions, and sensorineural hearing loss. The cerebral infarction was found to be mainly multiple and the frequently occurred locations were periventricular white matter, frontal lobe and basal ganglia. The logistic regression for chronic CS2 poisoning showed that the major factors were microaneurysm, cerebral infarction, polyneuropathy, other retina lesions, diastolic blood pressure, and sensorineural hearing loss. Among the approved group 117 patients were followed up continuously at the outpatient clinic, 62.4% of the patients had hypertension, 61.5% had polyneuropathy, 52.1% had cerebral infarction, 35.0% had hyperlipidemia, 29.9% had liver disease, 15.4% had psychiatric diseases, 6.0% had angina, and 4.3% had anemia. For the hypertensive patients, 1.9 kinds of antihypertensive drugs were needed to control the blood pressure, and the BP decreased from 164/101 mmHg to 131/81 mmHg.

Citations

Citations to this article as recorded by

Occupational Risk Factors for Stroke: A Comprehensive Review
Munyoung Yang, Hyoungseob Yoo, Seo-Young Kim, Ohwi Kwon, Min-Woo Nam, Kwang Hyun Pan, Mo-Yeol Kang
Journal of Stroke.2023; 25(3): 327. CrossRef
Occupational exposure to neurotoxic substances in Asian countries – Challenges and approaches
Monika Meyer-Baron, Eun A. Kim, Iman Nuwayhid, Gaku Ichihara, Seong-Kyu Kang
NeuroToxicology.2012; 33(4): 853. CrossRef
Work-related Cerebro-Cardiovascular Diseases in Korea
Dae-Seong Kim, Seong-Kyu Kang
Journal of Korean Medical Science.2010; 25(Suppl): S105. CrossRef
Occupational Neurological Disorders in Korea
Eun-A Kim, Seong-Kyu Kang
Journal of Korean Medical Science.2010; 25(Suppl): S26. CrossRef

65 View
1 Download
4 Crossref

Original Article

Study on the Progression of Biological Effects of Workers Following Termination of CS2 Exposure: In Cases of Peripheral Polyneuritis and Retinal Change: Y T Yum, K J Kim, S D Kim, E I Lee, H K Park, H R Jung, H K Kwon; Korean Journal of Occupational and Environmental Medicine 1994;6(2):348-363. Published online September 30, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.2.348

Abstract PDF

The object of this study was to evaluate the possibility of new development of polyneuropathy and microaneurysm in dundus in workers who did not have polyneuropathy and microaneurysm in dundus in the electromyogram(EMG) and ophthalmoscopic examination. The total number of subjects was 144 workers who had the EMG and funduscopic examination done at leat twice. There were two kinds of subjects. The one of subjects was a total of 120 workers who were examined at least twice in their annual health examination for carbon disulfide poisoning. The other subjects were 3 total of 24 volunteer workers who worked in the rayon manufacturing factory. The results were as follows; 1. There was no cases of polyneuropathy or microaneurysm in volunteers. 2. The new cases of polyneuropathy were detected in 12 (14.3%) out of 84 subjects, and those of microaneurysm in fundus were detected in 30 (26.5%) out of 113 subjects. 3. We investigated the variables showing difference between the new cases and other cases who had no polyneuropathy or microaneurysm in fundus in repeated examinations. The both of polyneuropathy and microaneurysm cases had higher commulative exposure index, and most of them were workers in the department of spinning where the concentration of CS0 in air was highest in the rayon manufacturing company. 4. There were no statistically significant variables by logistic regression analysis in the polyneuropathy cases, The cummulative index and the department were the statistically significant variable in the development of microaneurysms. ' 5. Above findings showed that workers who had high exposure history of CS2 as the workers in spinning department, had greater chance to develop the polyneuropathy or microaneurysm. But tHere were some limitations to conclude the association between the CS2 exposure and development of polyneuropatHy or microaneurysm. Limitations are follows short follow-up period, small number of cases, and possibility of measurement error including imperfect sensitivity or specificity of electrodiagnostic test and examiner's difference of ophthalmoscopic examination. Therefore more cases and longer follow-up period are needed to study the progression of polyneuropathy or microaneurysm.

Citations

Citations to this article as recorded by

Occupational Diseases in Korea
Seong-Kyu Kang, Eun A Kim
Journal of Korean Medical Science.2010; 25(Suppl): S4. CrossRef
Carbon Disulfide Poisoning in Korea with Social and Historical Background
Eunil Lee, Soonduck Kim, Haejoon Kim, Kwangjong Kim, Yongtae Yum
Journal of Occupational Health.1996; 38(4): 155. CrossRef

57 View
0 Download
2 Crossref

Original Article

Clinical Analysis of 8 Cases of Chronic Carbon Disulfide Poisoning in Workers Engaged in the Viscose Rayon Industry: Soon Duck Kim, Dong Bin Song, Yong Tae Yum; Korean Journal of Occupational and Environmental Medicine 1989;1(2):186-196. Published online November 30, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.2.186

Abstract PDF

The authors have experinced 8 cases of chronic carbon disulfide poisoning in workers engaged in the viacase rayon industry during the period between March 1987 and September 1988. Cases of carbon disulfide poisoning has not been reported in Korea till then. Carbon disulfide is primarily a neurotoxic poison, therefore those symptoms indicating central and peripheral nervous damage are very important. And it has toxic effects on the various organs such as skin, eye, ear, and respiratory, cardiovascular, gastrointestinal, hepatic, genitourinary, hematological, and endocrine system. Occupational histories were obtained, and clinical findings and laboratory findings were analysed on all cases. 1. Seven (7) cases had been exposed to carbon disulfide for more than 10 years, and 1 case has been exposed for 6 years. 2. Most common symptoms were neurological symptoms such as gait disturbance, extremity weakness, paresthesia, and speech disturbance. 3. Involvement of central nervous system was noted in 7 cases through abnormal findings of electroencephalography, brain computerized tomography, neurological signs, and psychological test. Needle electromyography and nerve conduction study showed polyneuropathy in all cases. Ophthalmological abnormalities were found in 7 cases, mainly retinal microaneurysms and peripheral constriction of the visual field. Renal damage appeared in 4 cases, increase of serum cholesterol and/or triglyceride level appeared in 3 cases, and dercrease of erythrocyte and hemoglobin appeared in 2 cases. And hypertenison appeared in 2 cases, and diabetes appeared in 1 case. One(1) case who has been exposed tn carbon disulfide for 6 years showed polyneuropathy and peripheral constriction of the visual field.

Citations

Citations to this article as recorded by

Occupational Neurological Disorders in Korea
Eun-A Kim, Seong-Kyu Kang
Journal of Korean Medical Science.2010; 25(Suppl): S26. CrossRef
Work-related Cerebro-Cardiovascular Diseases in Korea
Dae-Seong Kim, Seong-Kyu Kang
Journal of Korean Medical Science.2010; 25(Suppl): S105. CrossRef
Carbon Disulfide Poisoning in Korea with Social and Historical Background
Eunil Lee, Soonduck Kim, Haejoon Kim, Kwangjong Kim, Yongtae Yum
Journal of Occupational Health.1996; 38(4): 155. CrossRef

67 View
0 Download
3 Crossref

First
Prev
Page of 1
Next
Last

Search