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Case Report
Electrocardiogram abnormalities in antimony exposed workers in the automotive brake lining manufacturing industry: a case report
Ha-ram Jo, Seongyong Yoon, Jinseok Kim, Seong-yong Cho, Jong-min An, Gayoung Kim
Ann Occup Environ Med 2022;34:e16.   Published online June 27, 2022
DOI: https://doi.org/10.35371/aoem.2022.34.e16
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Antimony is used in catalysts, pesticides, brake systems, pharmaceuticals, and synthetic fire retardants in the plastic, paint, and rubber industries. Accumulation of trivalent antimony compounds in the body can cause cardiotoxic effects and increase the risk of electrocardiogram (ECG) abnormalities and sudden death. Antimony exposure can result in action potential prolongation, causing a cardiac repolarization delay, which appears as QTc prolongation and T-wave abnormalities on the ECG. There are no studies on antimony-associated cardiac toxicity in Korea.

Case presentation

Accordingly, the present study reports cases of ECG abnormalities in workers handling antimony trisulfide at a company located in the Gyeongsangbuk-do region. Nineteen workers employed at an automobile brake lining manufacturer were exposed to antimony trisulfide dust through thermoforming, grinding, and drilling processes. In 2020, the workers were reported to work 12-hour shifts, 5 days a week. The time-weighted average (TWA) of antimony trisulfide exposure measured in workers was 0.0028 mg/m3. Two workers were excluded from the analysis due to pre-existing medical conditions (cardiovascular disease). Of the remaining 17 workers, ECG abnormalities were found in 41% (seven out of 17: four with QTc prolongation and T-wave abnormalities; two with only T-wave abnormalities; and one with only QTc prolongation).

Conclusions

This case report outlines the first few cases in Korea in which potential cardiac toxicity caused by occupational exposure to antimony was identified. However, data regarding cardiac toxicity caused by antimony exposure are still lacking in Korea; thus, additional studies are needed to identify causal relationships.

자동차 브레이크 라이닝 제조업에 근무하는 안티몬 노출 근로자의 심전도 이상: 사례 보고서
배경
안티몬은 촉매, 살충제, 브레이크 시스템 및 의약품에 사용되며 플라스틱, 페인트 및 고무 산업에서 합성 난연제로 사용된다. 3가 안티몬 화합물이 체내에 축적되면 심장 독성 효과를 일으켜 심전도(ECG) 이상 및 급사의 위험이 증가할 수 있다. 3가 안티몬 화합물의 직업적 노출은 활동 전위 연장을 일으켜 심장 재분극 지연을 유발할 수 있으며, 이는 QTc 연장과 T파 이상으로 나타난다. 아직 국내에서는 3가 안티몬 화합물 노출과 관련된 심장 독성에 관한 연구는 없다. 이에 본 연구에서는 경상북도 지역에 위치한 회사에서 삼황화 안티몬을 취급하는 작업자의 심전도 이상 사례를 보고한다.
증례
자동차 브레이크 라이닝 제조업체에 고용된 19명의 작업자가 열성형, 연삭 및 드릴링 공정을 통해 삼황화 안티몬 분진에 노출되어 왔다. 2020년에 삼황화 안티몬에 노출 공정 근로자 19명은 주 5일 12시간 교대로 근무하였다. 근로자에게서 측정한 삼황화 안티몬 노출의 시간 가중 평균(TWA)은 0.0028 mg/m3였다. 2명의 근로자는 심장질환 과거력으로 인해 분석에서 제외되었다. 나머지 17명의 작업자 중 41%에서 ECG 이상이 발견되었다(17명 중 7명의 작업자: QTc 연장 및 T 파 이상 4명, T 파 이상 2명, QTc 연장 1명).
고찰
이 증례 보고서는 국내 최초로 직업상 안티몬 노출로 인한 잠재적인 심장 독성이 확인된 증례에 관해 설명한다. 그러나 우리나라에서는 안티몬 노출에 의한 심장 독성에 대한 자료가 아직 부족한 실정이다. 따라서 인과관계를 규명하기 위해서는 추가적인 연구가 필요하다.
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Case Report
Digital health care and arrhythmia: a case of WPW syndrome in South Korea, 2020
Eunchan Mun, Jihee Hong, Sunggu Kwon, Sung Ho Lee, Wonsool Kim, Changhwan Lee
Ann Occup Environ Med 2021;33:e8.   Published online March 24, 2021
DOI: https://doi.org/10.35371/aoem.2021.33.e8
AbstractAbstract PDFPubReaderePub
Background

The digital health care field is expanding from the daily monitoring of chronic diseases to the detection of acute diseases, such as arrhythmia. Wolff-Parkinson-White (WPW) syndrome, a congenital cardiac disorder due to accessory pathways, causes tachycardia, syncope, and even sudden death.

Case presentation

We presented a 26-year-old female office worker with WPW syndrome managing the disease with a wearable device and discussed its significance in occupational medicine. After reviewing the worker's electrocardiogram results, symptoms, and pulse rate records extracted from the wearable device, we referred the worker to a cardiologist for further evaluations such as electrophysiology study. The worker monitors her symptom recurrence with the wearable device following successful radiofrequency catheter ablation of the bypass tract.

Conclusions

A case of an office worker with WPW syndrome managing the disease using a smart watch is presented. Further research is required to ensure its scientific validity, and we suggest policymakers promptly introduce digital health care to occupational environments.


Citations

Citations to this article as recorded by  
  • Detection of Arrhythmias Using Smartwatches—A Systematic Literature Review
    Bence Bogár, Dániel Pető, Dávid Sipos, Gábor Füredi, Antónia Keszthelyi, József Betlehem, Attila András Pandur
    Healthcare.2024; 12(9): 892.     CrossRef
  • Smartwatches for Arrhythmia Detection and Management
    Chang H. Kim, Francoise A. Marvel, Aryan Majmudar, Natalie Horstman, David Spragg, Hugh Calkins, Eoin Donnellan, Seth S. Martin, Nino Isakadze
    Current Treatment Options in Cardiovascular Medicine.2024; 26(7): 189.     CrossRef
  • Application Effect of Whole-Process Seamless Nursing Model Based on Smart Healthcare Mode in Perioperative Period of Patients Undergoing Hematoma Removal
    Chang Liu, Rui Liu, Zhaohua Li, Meiling Tang, Fenghua Wang, Bhagyaveni M.A
    Journal of Healthcare Engineering.2022; 2022: 1.     CrossRef
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