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Research Articles
Cogeneration plant and environmental allergic diseases: is it really an eco-friendly energy source?
Jinyoung Moon
Ann Occup Environ Med 2020;32:e38.   Published online December 2, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e38
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background

Combined heat and power generation (CHP generation, also called ‘cogeneration’) is attracting public attention for its high thermal efficiency, without considering possible adverse environmental health effects.This study investigated the potential role of cogeneration plants in inducing 3 environmental diseases: asthma, allergic rhinitis, and atopic dermatitis.

Methods

From 1 January 2013 to 31 December 2017, the towns (dongs) of South Korea in which a cogeneration plant started operation were selected as study sites. For comparison, a matched control dong with the most similar Gross Regional Domestic Product for each case dong was selected. The numbers of outpatient visits, inpatient admissions, and emergency visits provided by the National Health Insurance Sharing Service (NHISS) were analyzed using an interrupted time-series design. For air pollutants, the concentrations of 5 air pollutants from the AIRKOREA dataset were used.

Results

A total of 6 cogeneration plants in 6 case dongs started operation during the study period. For overall case dongs, the pre-CHP trend was 1.04 (95% confidence interval [CI]: 1.038–1.042), and the post-CHP trend was 1.248 (95% CI: 1.244–1.253). The intercept change due to the CHP plant was 1.15 (95% CI: 1.137–1.162). For overall control dongs, the pre-CHP trend was 1.133 (95% CI: 1.132–1.135), and the post-CHP trend was 1.065 (95% CI: 1.06–1.069). The intercept change due to the CHP plant was 0.888 (95% CI: 0.878–0.899). Only for CO and NO2, the relative risk (RR) for overall case dongs was statistically significantly increased, and the RR for the overall control dongs was statistically insignificant.

Conclusions

Possible hazardous emissions, like CO and NO2, from cogeneration plants could induce environmental diseases in nearby community populations. The emissions from cogeneration plants should be investigated regularly by a governmental agency, and the long-term health outcomes of nearby community residents should be investigated.


Citations

Citations to this article as recorded by  
  • Regional impacts on air quality and health of changing a manufacturing facility’s grid-boiler to a combined heat and power system
    Elaheh Safaei Kouchaksaraei, Ali Khosravani Semnani, Kody M. Powell, Kerry E. Kelly
    Journal of the Air & Waste Management Association.2023; 73(10): 760.     CrossRef
  • Risk perceptions of a population living near a municipal waste incinerator and associated factors with the prevalence of environmental disease
    Dong Hyun Kim, Chae Kwan Lee, Jeong Ho Kim, Byung Chul Son, Chunhui Suh, Kunhyung Kim, Byeong Jin Ye
    Annals of Occupational and Environmental Medicine.2022;[Epub]     CrossRef
  • Assessing the Impact of Emissions of Severodonetsk Cogeneration Plant on the Health of the Urban Population
    I. V. Kravchenko, O. V. Suvorin
    Visnyk of V. N. Karazin Kharkiv National University series "Ecology".2021; (25): 81.     CrossRef
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Association between use of humidifier disinfectant and allergic rhinitis in Korean children: a cross-sectional study based on the eighth Panel Study on Korean Children (PSKC)
Tae Hwan Koh, Jong-Tae Park, Daeil Kwon, Kyeongmin Kwak
Ann Occup Environ Med 2020;32:e9.   Published online February 17, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e9
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background

Rhinitis was the most frequently diagnosed disorder among users of humidifier disinfectants (HDs). The aim of our study was to investigate on the relationship between allergic rhinitis (AR) and HD uses.

Methods

Our study used the data from the eighth Panel Study on Korean Children; a total of 1,540 participants were enrolled. The χ2 test and multiple logistic regression analyses were conducted to debunk the association between AR and HD uses.

Results

In our analysis, odds ratios (ORs) of doctor-diagnosed AR increased significantly when simply the response of whether HDs were used in the past was considered. When the brands of HD were considered, ORs of doctor-diagnosed AR were found to be increased significantly for those who have used polyhexamethylene guanidine phosphate/oligo(2-[2-ethoxy]-ethoxyethyl)guanidinium-containing HDs (model 3: 1.41, 95% confidence interval [CI]: 1.02–1.95). However, once duration of usage was additionally considered, ORs of doctor-diagnosed AR increased significantly only for those who have used chloromethylisothiazolinone/methylisothiazolinone-containing HDs for more than or equal to 3 months (model 3: 2.08, 95% CI: 1.17–3.69). Further, past use of HD was associated with significantly increased ORs of AR diagnosed before 2013 (model 3: 1.35, 95% CI: 1.02–1.79).

Conclusions

Results of our study suggest that past uses of HDs may be associated with an increased risk of AR.


Citations

Citations to this article as recorded by  
  • Exposures to humidifier disinfectant and various health conditions in Korean based on personal exposure assessment data of claimants for compensation
    Myeongjin Hong, Min Jae Ju, Jeonggyo Yoon, Wonyoung Lee, Seula Lee, Eun-kyung Jo, Seo-Youn Choi, Wonho Yang, Yoon-Hyeong Choi
    BMC Public Health.2023;[Epub]     CrossRef
  • Allergic rhinitis (pollinosis) and hygiene: learn from yesterday, live with COVID-19, hope for prevention
    Koichi Yoshida
    Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology.2023; 37(1): 18.     CrossRef
  • Health Effects Associated With Humidifier Disinfectant Use: A Systematic Review for Exploration
    Ji-Hun Song, Joonho Ahn, Min Young Park, Jaeyoung Park, Yu Min Lee, Jun-Pyo Myong, Jung-Wan Koo, Jongin Lee
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
  • Risk factors and protective factors in pediatric patients with allergic rhinitis
    Yoon Hong Chun, Minji Kim, Hyo-Bin Kim, Yeong-Ho Rha, Yang Park, Yong Mean Park, Myongsoon Sung, Youn Ho Shin, Hye Yung Yum, Kyung Suk Lee, Yong Ju Lee, Hye Mi Jee, Bong Seok Choi, Sun Hee Choi, Hyun Hee Kim
    Allergy, Asthma & Respiratory Disease.2022; 10(2): 73.     CrossRef
  • Need for individual-based evaluation to determine the association between humidifier disinfectants and health injuries
    Hyeong-Cheol Kim, Hyunil Kim, Eun-Chan Mun, Yesung Lee, Soyoung Park
    Annals of Occupational and Environmental Medicine.2021;[Epub]     CrossRef
  • Comparison study of dermal cell toxicity and zebrafish brain toxicity by humidifier sterilizer chemicals (PHMG, PGH, CMIT/MIT)
    Kyung-Hyun Cho, Jae-Ryong Kim
    Environmental Biology Research.2020; 38(2): 271.     CrossRef
  • Trends in prevalence of allergic diseases in Korean children: how and why?
    Kyung Suk Lee
    Clinical and Experimental Pediatrics.2020; 63(7): 263.     CrossRef
  • 30 View
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  • 5 Web of Science
  • 7 Crossref
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Original Article
Prevalence of Allergic Diseases of Workers Exposed to Phthalic Anhydride
Hyun Sul Lim, Soo Keun Kim, Ki Sik Kim
Korean Journal of Occupational and Environmental Medicine 1998;10(4):493-504.   Published online December 31, 1998
DOI: https://doi.org/10.35371/kjoem.1998.10.4.493
AbstractAbstract PDF
Phthalic anhydride (PA) is widely used in the production of alkyd and unsaturated polyester resins. It has been reported that some workers exposed to PA have developed dermatitis, rhinitis and asthma. The authors intended to investigate the prevalence of PA induced allergic diseases and to develop preventive measures of occupational diseases. Forty-five male workers from PA production and handling were selected as an exposure group. Forty-four male workers not handling PA at the same factory were chosen as a reference group. A symptom questionnaire, doctor's examination, eosinophil count, serum-total IgE and PA-specific IgE were done on the subjects. There were no significant differences in age, educational level, tenure or smoking habits between groups. Most clinical symptoms were significantly more frequent among the exposure group than the reference group: sneezing(62.2 %), rhinorrhea(57.8 %), nasal stuffiness(53.3 %), coughing(44.4 %) and nasal itching(35.6 %) were the major symptoms among the exposure group (p<0.01, p<0.05). There were no significant differences in eosinophil count and serum-total IgE between groups but the mean level in PA-specific IgE, in the exposure group, was statistically significantly higher than the reference group (p<0.01). Abnormal rates of eosinophil count, serum-total IgE and PA-specific IgE were not significantly different from each other. The prevalence rate was 68.9 % (31 cases) for allergic rhinitis in the exposure group, statistically significantly higher than the reference group (p<0.01). The prevalence rate was 6.7 %(3 cases) for bronchial asthma and contact dermatitis in the exposure group, not more statistically significant than the reference group. In the exposure group, the prevalence rate for age, educational level, tenure, smoking habits and use of protective devices are not statistically significant. In PA-specific IgE, sensitivity is 10.8 %, specificity is 100.0 %, positive predictability is 100.0 % and negative predictability is 61.2 % when criteria point is 3.5 KU/l or above. As a result, it was recognized that the exposure group had a high prevalence of PA induced allergic rhinitis. Also, in diagnosis of PA induced allergic diseases, medical histories and specific symptoms were the most important where as eosinophil count, serum total IgE are the only indirect informations. PA-specific IgE has been needed to evaluate the meanings more.

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