-
Relationship of Biological Indices of Manganese with Pallidal Index on MRI in Liver Cirrhotics
-
Younghee Choi, Neung Hwa Park, Jung Woo Shin, Hyo Kyung Kim, Sung Ryul Kim, Tae Heum Jeong, Ji Kang Park, Hun Lee, Cheol In Yoo, Choong Ryeol Lee, Ji Ho Lee, Yangho Kim
-
Korean Journal of Occupational and Environmental Medicine 2004;16(2):129-138. Published online June 30, 2004
-
DOI: https://doi.org/10.35371/kjoem.2004.16.2.129
-
-
Abstract
PDF
- OBJECTIVES
The objectives of this study were to clarify which biological manganese exposure indices reflect the pallidal signal intensities in magnetic resonance imaging (MRI) in liver cirrhotics. METHODS We examined whole blood, plasma, RBC and urinary manganese concentrations, as well as, brain MRI in 22 cirrhotic patients and 10 healthy controls. From MRI scans we calculated the signal intensity of the globus pallidus using the pallidal index (PI), the ratio of the globus pallidus to subcortical frontal white-matter signal intensity in axial T1-weighted MRI planes multiplied by 100. In addition, we studied the relationships between PI and other measurements. RESULTS The high signal intensity in the globus pallidus on T1-weighted MRI was observed in 18 (81.8%) patients. There was a significant correlation between whole blood and RBC manganese concentration, and PI on MRI. According to multiple linear regression, whole blood and RBC manganese concentration reflected PI on MRI better the other indices did. CONCLUSIONS Whole blood and RBC manganese concentrations could be useful as biological manganese exposure indices that reflect PI on MRI.
-
Occupational disease surveillance system in Busan, Ulsan, Kyung-Nam area
-
Jung Il Kim, Byung Gwan Kim, Jung Won Kim, Chang Ho Chae, Cheol Ho Yi, Dongmug Kang, Ji Hong Kim, Jin Ha Kim, Young Wook Kim, Young Ha Lee, Ji Ho Lee, Younghee Choi, Jung Ho Kim, Hyung Ryul Yun, Cheol In Yoo, Baek Geun Jeong, Tae Won Jang, Yun Gyu Kim, Dong Young Yun, Jin Uk Kang, Jong Eun Kim, Jin Hong Ahn, Dong Joon Lee, Joon Ho Jang, Kwang Young Lee, Hyu Ran Song, Yong Hwan Lee, Byung Man Cho, Hong Ryul Choi, Sang Baek Koh, Euna Kim, Yu Jin Lee, Young Seoub Hong, Kap Yeol Jung, Jung Man Kim, Joon Youn Kim
-
Korean Journal of Occupational and Environmental Medicine 2004;16(1):1-12. Published online March 31, 2004
-
DOI: https://doi.org/10.35371/kjoem.2004.16.1.1
-
-
Abstract
PDF
- OBJECTIVE: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases METHODS: 11 hospitals participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted.
RESULTS Between Apri1 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. Most of the HAVS cases came from shipbuilding, and 172 of them (92.7 %) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9 %). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6 %) and 4 (12.1 %) cases of occupational asthma, the agents included isocyanate and welding fume, respectively. 64.7 % of the cases of occupational skin diseases were contact dermatitis, and organic solvents and welding fume were the main agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10 (58.8 %) of the cases were diagnosed as squamous cell carcinoma and 5 (29.4 %) as adenoma. CONCLUSION This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.
-
Citations
Citations to this article as recorded by
- Work-relatedness of lung cancer by smoking and histologic type in Korea
Young-Il Lee, Sang-Gil Lee, Dong-Mug Kang, Jong-Eun Kim, Young-Ki Kim, Jong-Han Leem, Hwan-Cheol Kim Annals of Occupational and Environmental Medicine.2014;[Epub] CrossRef - Occupational Skin Diseases in Korea
Yeon-Soon Ahn, Min-Gi Kim Journal of Korean Medical Science.2010; 25(Suppl): S46. CrossRef
-
25
View
-
0
Download
-
2
Crossref
|