Annals of Occupational and Environmental Medicine

Soung Hoon Chang

16 Articles

Relationship between Community Social Support and Psychosocial Distress in Workers: Hwa Young Lim, Hyeong Su Kim, Young Hwan Choi, Soung Hoon Chang, Kun Sei Lee, Kyunghee Jung Choi, Won Ki Oh, Jae Wook Choi, Chun Hwa Jeoung; Korean Journal of Occupational and Environmental Medicine 2006;18(4):327-338. Published online December 31, 2006; DOI: https://doi.org/10.35371/kjoem.2006.18.4.327

OBJECTIVE: This study was performed to examine the relationship between community-based social support and psychosocial distress in workers.
METHODS
The study subjects were 596 workers recruited from 11 companies in Chungju city. A structured questionnaire was used to assess sociodemographics, health-related behaviors, job characteristics, job stress, work-based social support, community-based social support and level of psychosocial distress.
RESULTS
Hierarchical multiple regression analysis showed that workers with no chronic disease, exercise and sufficient sleep had a higher score of psychosocial distress than those with chronic disease, no exercise, and not enough sleep. Coworker's work-based social support and community-based social support were negatively associated with psychosocial distress. The R square value of total independent variables on psychosocial distress was 0.409, and that of community-based social support on psychosocial distress was 0.052.
CONCLUSION
This study showed that community-based social support served as a protective factor against psychosocial distress in some workers. We recommend the establishment of a worksite stress reduction program in occupational level as well as community-based social support.

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The Informative Support and Emotional Support Classification Model for Medical Web Forums using Text Analysis
Jiyoung Woo, Min-Jung Lee, Yungchang Ku
Journal of the Korea society of IT services.2012; 11(sup): 139. CrossRef
Job Stress Level and It's Related Factors in Firefighters
Mi-Suk Choi, Dong-Ha Ji, Jin-Woo Kim
Journal of the Korea Academia-Industrial cooperation Society.2012; 13(10): 4917. CrossRef

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Relationship between Injury Occurrence and Workplace Organization in Small-sized Manufacturing Factories: Kun Sei Lee, Hyeongsu Kim, Soung Hoon Chang, Kyung Hee Jung-Choi, Won Ki Oh, Jae Wook Choi, Kwan Hyung Yi, Ji Young Oh; Korean Journal of Occupational and Environmental Medicine 2006;18(2):73-86. Published online June 30, 2006; DOI: https://doi.org/10.35371/kjoem.2006.18.2.73

Abstract PDF

OBJECTIVE: This study evaluated the relationship between injury occurrence and workplace organization in small-sized, manufacturing factories in Korea.
METHODS
Using data from the 2004 Occupational Safety and Health Survey in Korea, this study compared workplace organizational factors (general characteristics, employee characteristics and health and safety characteristics) with injury occurrence of 1,866 small-sized, manufacturing factories (65,921 population factories after weighting). General characteristics of factories comprised location, type and classification of industry. Employee characteristics comprised proportion of manual workers and female workers, average working hours per week and shiftwork. Health and safety characteristics comprised type of safety and health manager, committee for occupational safety and health, labor union, health and safety regulation, monthly health and safety training time, score of health and safety activity and score of safety culture.
RESULTS
The following characteristics of injury-occurrence in small-sized, manufacturing factories were determined by multivariate analysis. In terms of general characteristics, the risk of injury-occurrence was higher in Jeolla area than Gyeongin area in outside associate than other enterprises and in coke, refined petroleum products and nuclear fuel, wood and products of wood, food products and beverages and fabricated metal products, except machinery and furniture industries than television and communication equipment and apparatus industries. In terms of employee characteristics, injury-occurrence significantly increased in factories with greater proportion of manual worker and with a higher rate of working hours per week. But significantly decreased in factories with a higher proportion of female workers. In terms of health and safety characteristics, injury-occurrence significantly increased in factories with a self-appointed safety manager, with unorganized union, with a more active committee for occupational safety and health, with unimplemented health and safety regulations, with longer monthly safety and health training time, and with a lower score of safety culture.
CONCLUSIONS
This study demonstrated that several factors of workplace organization were significantly related with injury-occurrence in factories. These findings are supposed to raise the need for making efforts in workplace organization to improve injury prevention.

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A Policy Intervention Study to Identify High-Risk Groups to Prevent Industrial Accidents in Republic of Korea
Kwan Hyung Yi, Seung Soo Lee
Safety and Health at Work.2016; 7(3): 213. CrossRef
Validation of Performance Indicators for Evaluation of Workplace Health Promotion
Seung Hee Ho, Young Moon Chae
American Journal of Health Promotion.2015; 29(6): 402. CrossRef
A basic research on risk control measure for reducing the fishermen's occupational accident in offshore and coastal fishing vessel
Wook-Sung Kim, Young-Bok Cho, Seok-Jae Kim, Kyong-Jin Ryu, Yoo-Won Lee
Journal of the Korean society of Fisheries Technology.2014; 50(4): 614. CrossRef
Research on the Characteristics of Working Conditions and Occupational Safety and Health in the Special form Workers
Kwan Hyung Yi
Journal of the Korean Society of Safety.2014; 29(4): 147. CrossRef
Effects of health and safety problem recognition on small business facility investment
Jisu Park, Harin Jeong, Sujin Hong, Jong-Tae Park, Dae-Sung Kim, Jongseo Kim, Hae-Joon Kim
Annals of Occupational and Environmental Medicine.2013;[Epub] CrossRef

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Cost of Work-related Cerebrovascular and Cardiac Disease: Hyeong Su Kim, Soung Hoon Chang, Jae Wook Choi, Kun Sei Lee, Cheong Sik Kim, Jun Young Lee, Ji Young Oh; Korean Journal of Occupational and Environmental Medicine 2002;14(3):288-300. Published online September 30, 2002; DOI: https://doi.org/10.35371/kjoem.2002.14.3.288

Abstract PDF: OBJECTIVES
The purpose of this study was to estimate the cost, with a focus on forecasting the expenditure on industrial accident compensation insurance, arising from workrelated cerebrovascular and cardiac disease.
METHODS
We used a total of 4,480 work-related cerebrovascular and cardiac disease data points, collected between 1995 and 2000, based on the year of occurrence, and which had been approved by industrial accident compensation insurance. Firstly, we calculated the number of approved cases per 100,000 workers benefiting from industrial accident compensation insurance between 1995 and 2000. We then forecasted the numbers of work-related cases of cerebrovascular and cardiac disease for the period from 2001 through 2005 using a linear regression equation. Secondly, we analysed the expenditure on industrial accident compensation insurance due to work-related cerebrovascular and cardiac disease, and estimated the expenditure per capita for the former period. Thirdly, we estimated the expenditure on industrial accident compensation insurance due to work-related cerebrovascular and cardiac disease for the latter period based on the cohort of occurrence year.
RESULTS
Approved cases per 100,000 workers for work-related cerebrovascular and cardiac disease were 3.36 in 1995 and 13.16 in 2000. It is expected that the approved cases would be 1,336 (95 % CI 1,211-1,460) in 2001 and 1,769 (95 % CI 1,610-1,931) in 2005, based on the year of occurrence. The mean expenditure per capita was estimated to be 75 million won, which comprised of 19 million won for medical care benefits and 56 million won for other benefits. It was anticipated that the claims for the 2001 cohort would be 107.9 billion won and 192.4 billion won for the 2005 cohort.
CONCLUSIONS
The magnitude of the economic burden of work-related cerebrovascular and cardiac disease is substantial. From an economic perspective, this study proves the importance and need for the management of work-related cerebrovascular and cardiac disease.

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The Similar Exposure Group and Exposure Variation in Ship-Building Painters: Focused on Xylene Exposure: Sang Baek Koh, Young Man Roh, Hyeon Woo Yim, Yong Chul Shin, Soo Keun Kim, Hong Ryul Choi, Jai Young Kim, Soung Hoon Chang; Korean Journal of Occupational and Environmental Medicine 2001;13(4):413-422. Published online December 31, 2001; DOI: https://doi.org/10.35371/kjoem.2001.13.4.413

Abstract PDF

OBJECTIVES
This study was conducted to assess the concentration of xylene exposure and exposure variability of a similar exposure group(SEG) in accordance with job title and confined space.
METHOD
The study subjects included 28 workers working in the painting process in the ship-building industry. Measurement of subjects were repeated three times. Within and between-worker exposure variance components were estimated from log-transformed exposure concentrations employing a one-way nested random effects analysis of variance model. A uniformly exposed group was defined as one where the between-worker variance(sigmaB2) was less than or equal to 0.031 or bwR95 RESULT
The results indicated that, contrary to popular belief, similar exposed groups based on job title were heterogeneous. The between-worker variance(sigmaB 2) is large(>or=0.031) and the ratios of the 97.5th and 2.5th percentile workers of the log normally distributed exposures of each group of workers was more than 2. However dividing job title into confined space(in-block, out-block, in/out-block) decreased the between-worker exposure variability.
CONCLUSION
This study focused on the quantitative aspects of exposure in painters in the ship-building industry. We cannot accept the assumption that SEG are uniformly exposed, as a major component of variation in exposure relates to differences in tasks or other factors. Therefore, the observational schemes can be improved by investigating jobspecific task and practice.

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Overview of occupational cancer in painters in Korea
Jun-Pyo Myong, Younmo Cho, Min Choi, Hyoung-Ryoul Kim
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
The Work Environment and Wearing Conditions of Industrial Protective Clothing in Shipbuilding Workshops
Hyun-Sook Bae, Min-Young Kim
Journal of the Korean Society of Clothing and Textiles.2012; 36(5): 512. CrossRef

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Effect of Occupational Lead on Male Sex Hormones: Hyeong Su Kim, Soung Hoon Chang, Won Jin Lee, Jae Wook Choi, Jong Tae Park, Nam Won Paik, Rok Ho Kim; Korean Journal of Occupational and Environmental Medicine 2001;13(1):44-54. Published online March 31, 2001; DOI: https://doi.org/10.35371/kjoem.2001.13.1.44

Abstract PDF: OBJECTIVES
This study was performed to evaluate the relationship between biological markers of lead exposure and level of sex hormones in men occupationally exposed to lead.
METHODS
In this study, 33 male workers who employed at smelting and battery factories were compared with 33 male workers who were not exposed to lead. As biological markers of lead exposure, hemoglobin, ZPP, blood lead and urine lead were measured. As sex hormones, FSH, LH, testosterone, SHBG and FTI were determined.
RESULTS
Hemoglobin level was significantly lower in exposed than in nonexposed group. Level of ZPP, blood lead, and urine lead were significantly higher in exposed than in nonexposed group. There was a trend that level of FSH, testosterone, SHBG, and FTI was lower in exposed than in nonexposed group respectively, but there were no statistical significance. In exposed group, FSH level was correlated with age, ZPP, and blood lead; testosterone level was correlated with hemoglobin, blood lead, urine lead, and SHBG; and FTI level was correlated with age.
CONCLUSIONS
Level of some sex hormones were lower in exposed than in nonexposed group but there were no statistical significance between the exposed and the nonexposed group. But level of sex hormones were correlated with several biological markers of lead in exposed group. It suggests that occupational lead exposure might affect sex hormones.

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A Meta-analysis on the Association between Bladder Cancer and Glutathione S transferase mu Genetic Polymorphism: Sang Baek Koh, Bong Suk Cha, Jong Ku Park, Chun Bae Kim, Myung Gun Kang, Ki Woong Kim, Won Jin Lee, Soung Hoon Chang; Korean Journal of Occupational and Environmental Medicine 1999;11(1):13-23. Published online March 31, 1999; DOI: https://doi.org/10.35371/kjoem.1999.11.1.13

Abstract PDF: This study was conducted to integrate the results of studies which assess the relationship between bladder cancer and Glutathione S transferase mu genetic polymorphism. We retrieved the literatures using MEDLINE search, with bladder cancer and Glutathione S transferase as key words, which were reported from 1980 to October 1998. The criteria for quality evaluation were as follows; 1) The paper should have histologically confirmed bladder cancer as case definition. 2) The paper should use the GSTM1 gene typing as method for analysis. Among 59 retrieved articles, fourteen studies were selected for quantitative meta-analysis. The overall effect size of the risk of bladder cancer due to GSTM1 was calculated by common odds ratio. Before the integration of each effect sizes into common effect sizes, the homogeneity test were conducted. All studies were case control design and cases were transitional cell carcinoma or squamous cell carcinoma of bladder. And only four papers used matching technique. Homogeneity of studies were rejected by Breslow-Day test(P<0.01), so random effect model was used for evaluation of odds ratio. The overall odds ratio of GSTM1 associated with bladder cancer was 1.55 (95% confidence interval 1.27 to 1.90) and cumulative odds ratio became more stable when the study subjects were over 1,500. Our result suggested that positive association be found between GSTM1 genetic polymorphism and bladder cancer.

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Sister Chromatid Exchanges in Workers Occupationally Exposed to Ethylene Oxide: Soung Hoon Chang, Won Jin Lee, Cheong Sik Kim, Cheong Hyun Hwang, Jong Tae Park, Dae Seong Kim, Young Whan Kim; Korean Journal of Occupational and Environmental Medicine 1998;10(4):428-437. Published online December 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.4.428

Abstract PDF

Operators of hospital sterilizers who use ethylene oxide (EtO) were studied to determine the exposure of EtO level and the frequency of sister chromatid exchanges (SCEs) from June 12 to July 20, 1997. To evaluate SCEs in the peripheral blood cells, we selected 22 workers at the central supply room of 4 university hospitals and 22 unexposed workers at the same hospitals according to match sex, age, and smoking habit and also did questionnaires. The mean air concentrations (8-hr TWA) of EtO at 4 university hospitals were less than 1 ppm. The SCE frequencies in exposed workers to EtO and controls were normally distributed. The SCE frequencies in exposed workers to EtO and controls were 6.42+/-.63, 5.86+/-.69, respectively and their differences were statistically significant (p=0.0093). But there were no statistically significant differences in smoking, alcohol intake, coffee drinking. Especially smokers who exposed to EtO were increased SCE statistically significant than the exposed group who did not smoke.

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Analysis of Micronuclei and Its Association with Genetic Polymorphisms in Hospital Workers Exposed to Ethylene Oxide
Sun-Yeong Lee, Yang-Jee Kim, Young-Joo Choi, Joong-Won Lee, Young-Hyun Lee, Mi-Yeon Shin, Won Kim, Chung-Sik Yoon, Sung-Kyoon Kim, Hai-Won Chung
Korean Journal of Environmental Health Sciences.2011; 37(6): 429. CrossRef

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Plasma Malondialdehyde, alpha-tocopherol and Erythrocyte Superoxide Dismutase Activity with Blood Level of Heavy Metals in Welders: Won Jin Lee, Cheon Hyun Hwang, Soung Hoon Chang, Byung Chul Chun, Hae Joon Kim; Korean Journal of Occupational and Environmental Medicine 1998;10(2):240-250. Published online May 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.2.240

Abstract PDF: We investigated the association between the oxidative stress and the concentration of heavy metals in blood among welders. The study subjects were male manual CO2 welders(N=127) exposed to several heavy metals. The age distribution was from 20 to 63 (GM=33.7) and the geometric mean(GM) of work duration was 4.2 years. We analyze the level of blood lead, cadmium, managese and chromium which was related with the oxidative stress in the animal studies. Blood selenuim, plasma malondialdehyde (MDA), plasma alpha-tocopheol and orythrocyte superoxide dismutase (SOD) were analyzed as biological markers of the oxidative stress. The results of univariate analysis showed that the plasma MDA was significantly correlated with D-tocopherol (r=0.327) and blood selenium (r=0.313) concentration. But we could not find out any relationship between the erythrocyte SOD activities and those metal concentrations. Neither smoking nor alcohol consumption was related to the level of heavy metals and the oxidative stress biomarkers. As the results of multiple regression analysis with stepwise selection method, 1) the change of MDA level were dependant with the level of alpha-tocopherol and blood selenium concentration (R2=19.7), 2) the plasma alpha-tocopherol level was dependant with MDA and blood chromium concentration (R2=15.6), 3) in case of erythrocyte SOD activity, only the duration of work was significantly selected.

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A Study of the Correlation Between the Activity of Erythrocyte Pyrimidine 5'-Nucleotidase and Urinary N-Acetyl-beta-D-Glucosaminidase in Lead Exposed Workers: Soung Hoon Chang, Cheon Hyun Hwang, Won Jin Lee, Soung Soo Lee, Byung Kook Lee, Hong Kyu Suh, Jae Wook Choi; Korean Journal of Occupational and Environmental Medicine 1997;9(2):258-266. Published online June 30, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.2.258

Abstract PDF: In this study, we measured the activity of the erythrocyte pyrimidine 5'-nucleotidase (P5N) and urinary N-acetyl-beta-D-glucosaminidase (NAG) from 154 workers exposed to lead and 43 workers not exposed. We analyzed the correlation of the P5N activity and NAG activity with other biological exposure indices of lead such as blood lead (PbB) and zinc protoporphyrin (ZPP). The measurement was performed by using high performance liquid chromatography (HPLC), spectrophotometer and atomic absorption spectrophotometer. The results are as follows: 1. The mean value of P5N activity for workers exposed to lead was 9.50+/-.13 micromol uridine/hr/g Hb and 11.60+/-.2 micromol uridine/hr/g Hb for workers not exported. The P5N activity showed a normal distribution, but the other indices of lead showed logarithmic normal distributions. 2. The P5N activity and ZPP were decreased as PbB wag increased. But the NAG activity had no correlation with changes of PbB. 3. The correlation coefficients of the P5N activity with other biological exposure indices of lead such as PbB, ZPP, NAG activity were -0.72, -0.55, and 0.05, respectively. We speculated that the P5N activity can be used as a reliable biological exposure index of lead but NAG activity can be used as a biological management index of lead.

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Musculoskeletal Diseases of Upper Extremities Among the Electronic Assembly Workers and Telecommunication Workers: Jae Wook Choi, Yorig Tae Yum, Dong Bin Spng, Jong Tae Park, Soung Hoon Chang, Jung Ae Choi; Korean Journal of Occupational and Environmental Medicine 1996;8(2):301-319. Published online September 30, 1996; DOI: https://doi.org/10.35371/kjoem.1996.8.2.301

Abstract PDF

The purpose of this study is to investigate the current status of and to collect the basic informations of musculoskeletal diseases of upper extremities in manufacturing and telecommunication companies. The subjects were 213 workers, consisted Of 98 manufacturing workers and 115 telephoBfi operators. The musculoskeletal ,symptom survey, Job safety analysis (JSA), and medical examinations including neurologic, and'nerve.cqnduction velocity (NCV) test were conducted.: All workers were women in company A, while the other composed of 68(69.4%) men and 30(30.6%) women. The results were as follows: 1. The rates of self-reporting symptoms in each company were 85.2% at the neck, 81.1% at the shoulder joint, 73.0% at the wrist joint and 34.8% at the elbow joint in company A, while 56.1% at the shoulder joint, 51.2% at the neck and 23.5% at the elbow joint in company B in order. 2. No relationship was observed between the work duration and symptom rate in company A, but the highest symptom rate was observed at the neck in 10-19 year work duration group, at the shoulder, elbow and wrist joint in 5-9 year work duration group in company B. 3. Over the 22.8% of total workers in this study having symptoms got medical treatment at the medical clinics or drug stores, but there was no statistical difference between both companies. 4. In company A, 16(13.9%) workers were classified as D category, 12(10.4%) workers as C category and 2(1.7%) workers as R category among 115 workers. And D category was 10(10.2%), C category 31(31.6%) and R category 4(4.0%) among 98 workers in company B. D category means disease category needed futher treatment, C category means disease category needed no treatment and R category means recheck category, needed futher evaluation. 5. The types of musculoskeletal disorders including D, C, and R category were 46 cases(D 13, C 30, R 3) of tension neck .syndrome (TNS), 16 cases (D 3, C 8, R 5) of carpal tunnel syndrome (CTS), 5 cases of De Quervain's disease, 3 cases of lateral epicondylitis, 3 cases of bicipital tendinitis, 3 cases of rotator cuff tendinitis, 2 cases of medical epicondylitis, and 5 cases of cervical disc syndrome. 6. In company A, the total cases of 11 TNS, 8 CTS, 3 De Quervain's disease, 3 lateral epicondylitis, 3 rotator cuff tendinitis and 1 cervical disc syndrome were diagnosed and so were total cases of 35 TNS, 8 CTS and 4 cervical disc syndrome in company B. 7. By stepwise multiple regression analysis with dichotomization of musculoskeletal disease, the following odds ratios were significantly high (p<0.05)-sex (2.707) and age(l.926).

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Effects of the Health Support Network Project on Musculoskeletal Disorders of Females
Deok-Ju Kim, Hee-Jung Han, Yeong-Ae Yang
The Korean Journal of Health Service Management.2015; 9(1): 169. CrossRef
Work-related Musculoskeletal Disorders in Korea Provoked by Workers’ Collective Compensation Claims against Work Intensification
Dongmug Kang, Youngki Kim, Young-Il Lee, Sangbaek Koh, Inah Kim, Hoonkoo Lee
Annals of Occupational and Environmental Medicine.2014;[Epub] CrossRef
Study on the Musculoskeletal Subjective Symptoms Disorders and Health Promotion Behavior of Daily Plant Construction Workers in One Area
Ja-Sook Kim, Ja-Ok Kim, Ji-Yong Seo, Hack-Sun Kim
Korean Journal of Occupational Health Nursing.2014; 23(1): 28. CrossRef
The Trends and Status of Work-related Musculoskeletal Diseases under Korean Worker's Compensation System
Kyung Ha Kim, Rah Il Hwang, Min Hyun Suk
Korean Journal of Occupational Health Nursing.2013; 22(2): 102. CrossRef
Risk Factors of Work-related Upper Extremity Musculoskeletal Disorders in Male Shipyard Workers: Structural Equation Model Analysis
Byung-Chan Park, Hae-Kwan Cheong, Eun-A Kim, Soo Geun Kim
Safety and Health at Work.2010; 1(2): 124. CrossRef

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A Study on the Correlation of Ambient Toluene and Xylene with Biological Monitoring Index: Soung Hoon Chang; Korean Journal of Occupational and Environmental Medicine 1995;7(2):295-305. Published online October 31, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.2.295

Abstract PDF

In order to study the correlation of ambient toluene and xylene exposure with their biological monitoring indices, we measured the concentration of toluene and xylene in the workplace. We also measured their biological monitoring indices of workers from August to November in 1994. The exposed group consisted of 103 male workers and the non-exposed group consisted of 34 male workers. The ambient concentration of toluene was 44.7 +/-55.4 ppm and that of xylene was 2.35+/-2.15 ppm. The urinary concentration of hippuric acid in exposed group was 1.72+/-1.53 g/g creatinine and that of non-exposed group was 0.34+/-0.28 g/g creatinine. The difference was statistically significant between two groups (p<.0.001). The urinary concentration of o-cresol in exposed group was 692.9+/-710.8 ug/g creatinine and that of non-exposed group was 184.7+/-167.6 microgram/g creatinine. The difference was also statistically significant between two groups (p<0.001). The urinary concentration of methylhippuric acid which was compensated with urinary creatinine in I exposed group was 62. 7+/-104.6 mg/g creatinine and that of non-exposed group was 64.0+91.5 mg/g creatinine. However the difference was not statistically significant between two groups (p>0.05). When compensated with urinary creatinine, the correlation coefficient of ambient toluene with urinary hippuric acid and ocresol were 0.63(p=0.0001) and 0.65(p=0.0001), respectively. When compensated with urinary specific gravity, the correlation coefficient of ambient toluene with hippuric acid and ocresol were 0.525 (p=0.0001) and 0.547 (p=0. 0001), respectively. The compensation method using urinary creatinine provided a higher correlation coefficient. We could not find any statistically significant differences between the duration of work and other variables (urinary hippuric acid, o-cresol and methylhippuric acid). In order to monitor biological indices of toluene-exposed workers, we suggest the measurement of urinary hippuric acid rather than o-cresol. As the compensation method, we suggest to use urinary creatinine rather than urinary specific gravity.

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Effects of the Exposure to Polycyclic Aromatic Hydrocarbons or Toluene on Thiobarbituric Acid Reactive Substance Level in Elementary School Children and the Elderly in a Rural Area
Dae-Seon Kim, Chul-Ho Lee, Sang-Yong Eom, Tackshin Kang, Yong-Dae Kim, Heon Kim
Journal of Preventive Medicine and Public Health.2008; 41(1): 61. CrossRef

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A Study on the Reference Value of Erythrocyte Pyrimidine 5'-Nueleotidase Activity: Jong Yeon Kim, Hae Joon Kim, Soung Hoon Chang, Kwang Jong Kim; Korean Journal of Occupational and Environmental Medicine 1995;7(1):63-81. Published online February 28, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.1.63

Abstract PDF: For the purpose of determining the reference value of erythrocyte pyrimidine 5'-nucleotidase (P5N) activity as a biological indicator to lead exposure, this study was conducted on the total of 225 healthy men who had not been exposed to lead occupationally, in July, 1994. The parameters selected in this study were age, hemoglobin, hematocrit, number of red blood cell, mean corpuscular hemoglobin (MCH), mean corpuscular herloglobin concentration (MCHC), blood lead, and erythrocyte P5N activity. The blood lead concentrations were measured using a flameless atomic absorption spectrophotometer, and erythrocyte P5N activities by Sakai's simple method using a HPLC(1986). The results were obtaina as follows; 1. The distribution of blood lead concentrations revealed log-normal distribution, and geometric mean and standard deviation of blood lead were 4.09 microgram/dl and 1.55 microgram/dl, respectively. 2. The erythrocyte P5N activity showed normal distribution, and the mean and standard deviation of the erythroeyte P5N activity were 12.34 umole uridine/h/g Hb and 2.21 umole uridine/h/g Hb, respectively. 3. All of the selected variables including blood lead concentration did not affect the erythrocyte P5N activity. Although the erythrocyte P5N activities were negatively associated with blood lead level, the correlation coefficient was not statistically significant. 4. From the result of this study, 8.7 micromole uridine/h/g Hb was obtained as a reference value of erythrocyte pyrimidine 5'-nucleotidase activity for the healthy adult male who had not been exposed to lead occupationally.

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A Study on the Activity of Erythrocyte Pryrimidine 5'-Nucleotidase in Workers Exposed to Lead: Soung Hoon Chang, Yong Tae Yum; Korean Journal of Occupational and Environmental Medicine 1994;6(1):85-97. Published online February 28, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.1.85

Abstract PDF: In this study, we measured the activity of the erythrocyte pyrimidine 5'-nucleotidase(P5N) for 83 workers exposed to lead in their workplace, and analyzed the correlation of the activity with other biological exposure indices of lead. The measurement was performed by using a high performance liquid chromatography (HPLC) with a reverse phased ODS column. The results are as follows; 1. The correlation of the erythrocyte P5N activity with the concentration of blood lead(PbB) was shown to be statistically significant (r=-0.71, p=0.0001). 2. For a group of subjects whose PbB was less than 10microgram/dl, the erythrocyte P5N activity was 14.9+/-1.5 micromole uridine/h/g Hb. 3. For medical surveillance, this study suggests the erythrocyte P5N activity of 12 micromole uridine/h/g Hb is equivalent to 40 microgram/dl of PbB. 4. The correlation coefficients of the erythrocyte P5N activity with other biological exposure indices of lead such as PbB, ZPP, ALA-U, PBU, CP-U, ALAD, and log ALAD were -0.71, -0.64, -0.57, -0.51, -0.50, 0.46 and 0.64, respectively. 5. The correlation coefficients of the PbB with other biological exposure indices of lead for ALAD, P5N, ZPP, PBU, CP-U, and ALA-U were -0.76, -0.71, 0.68, 0.59, 0.42, and 0.41, respectively. The erythrocyte P5N activity can be used as a reliable biological exposure index of lead.

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A study on the correlation between the lead concentration in air and in blood among lead workers: Seok Gun Park, Kwang Jong Kim, Soung Hoon Chang; Korean Journal of Occupational and Environmental Medicine 1991;3(1):98-103. Published online February 28, 1991; DOI: https://doi.org/10.35371/kjoem.1991.3.1.98

Abstract PDF

No abstract available.

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Low-Level Lead Exposure Among South Korean Lead Workers, and Estimates of Associated Risk of Cardiovascular Diseases
Kyeong-Ran Kim, Sang-Won Lee, Nam Won Paik, Kyungho Choi
Journal of Occupational and Environmental Hygiene.2008; 5(6): 399. CrossRef
Cross-Sectional Analysis of Blood Lead Level of Entire Korean Lead Workers
Kyeong-Ran KIM, Sang-Won LEE, Nam-Won PAIK
Industrial Health.2006; 44(2): 318. CrossRef

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Mercury Concentration in Air and in Urine of Workers in A Fluorescent Lamp Manufacturing Factory: Seung Hoi Park, Kwang Jong Kim, Soung Hoon Chang, Chul Whan Cha; Korean Journal of Occupational and Environmental Medicine 1989;1(2):197-205. Published online November 30, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.2.197

Abstract PDF: In order In interpret the relationship among many variables, urinary mercury and at the same time mercury concentration in air were measured for 254 workers of a fluorescent lamp manufacturing factory. And monthly mercury consumption amounts, numbers of monthly producing fluorescent lamps, numbers of inferior lamps and numbers of breakage lamps, numbers of vacuum exhaustion pumps and frequencies of mercury infusion were also investigated from January 1988 to March in 1989. The results were as follows; 1. On the mercury concentration in air by producing line and by working site, all of them were exceed the threshold limit value (0.05mg/m(2)). 2. The highest mercury concentration in air by sampling point was found at the floor of workplace (0.334mg/m(2)) and next were at vacuum exhaustion pimp (0.183mg/m(2)), and breathing zone of workers (0.103mg/m(2)) in order. 3. The highest mean of the mercury concentration in urine by producing line was the automatic exhausting line (80.8microgram/1) and next were high speed exhausting line (72.4microgram/1), and Manual exhausting line (35.8microgram/1) in order. Distribution of workers of the mercury concentration in urine more than 200microgram/1 by working site was the highest (10%) in the vacuum exhaustion pump part and next were sealing part (6.6%), packing part (4.6%), and stem part (4.1%) in order. 4. The correlation coefficient between mercury concentration in urine and in air was the highest (0.302) and next were numbers of breakage lamps (0.223), frequencies of mercury infusion (0.223), numbers of inferior lamps (0.205) in order.

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A Study on the Current System of Occupational Physician in Korea: Eun Joo Lee, Soung Hoon Chang, Dong Bin Song; Korean Journal of Occupational and Environmental Medicine 1989;1(1):32-38. Published online February 28, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.1.32

Abstract PDF: According to law the employer who has over 50 workers in his enterprise should employ an occupational physician as industrial health manager. The main role of the occupational physician is emphasized to the prevention of occupational diseases rather than the treatment and he should be the team leader of industrial health personnel. But this ideal system in terms of stipulations has lots of problems in operation. Therefore this study was designed to prove the attitude of reception, real condition and work content of the occupational physician in enterprise. The survey was done in 500 stratified random sampled enterprises over the country from July through September in 1987 by mailing questionnaire. As a result of the response from 145 enterprises, more than 85% of enterprise displaced occupational physicians. Among the occupational physicians 43% of them has no allowance for their working as industrial health managers and are payed less than 100,000 won monthly. And 66% of them visited only once a month or none enterprise, where they were nominated as a occupational physician managers. The major work content of occupational physician was doing outpatient clinic or regular physical examination rather than prevention of occupational disease. And it shows a deep discrepancy with the object of law or the expect of enterprise in which industrial hygiene and health education are more stressed for prevention of occupational diseases. The most of industrial workers showed no interest in work of occupational physician. As a conclusion, the current system of industrial health manager has maintained on paper formally and is apt to fall into making outward show. It is urgent for government and enterprise to find a solution which can be practically used the system of occupational physician. The work content of occupational physician is required high advanced knowledge and experience, and it should be operated dual system by special field and nonspecial field.

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