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A Case of Hypersensitivity Pneumonitis in a Worker Exposed to Metal Working Fluid
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Sun Wung Lee, Dong hee Ko, Ku Won Chin, Dong Uk Park, Jung Tak Lee, Yoon Hee Song, Sang Yoon Lee
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Korean Journal of Occupational and Environmental Medicine 2008;20(1):37-45. Published online March 31, 2008
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DOI: https://doi.org/10.35371/kjoem.2008.20.1.37
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 Abstract
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- INTRODUCTION: There have been no reports of hypersensitivity pneumonitis caused by metal working fluids in Korea, despite their existence in other countries. Here, we report the first such case, along with an assessment of work-relatedness through exposure assessment.
CASE
REPORT: A 64-year old male patient visited the hospital with dyspnea after metal pipe cutting for about a year. He was diagnosed with hypersensitivity pneumonitis from the evidence of specific exposure history, clinical symptoms, and radiologic findings. The air exposure levels of the oil mist, endotoxin, total bacteria and fungus in the work environment was TWA(8-hr) 0.531 mg/m3, 6.33 EU/m3, 100 CFU/m3 and 75 CFU/m3, respectively. The concentrations of the endotoxin, total bacteria and fungus within the metal working fluid was 1.5x10(4) EU/mL, 4.6x10(5) CFU/mL and 1.8x10(5) CFU/mL, respectively.
DISCUSSION
Although the patient did not receive a specific precipitating antibody test, the microbial concentration within the metal working fluid was higher than normal and similar to previous case reports, The oil mist level in the air exceeded the NIOSH REL and ACGIH NIC, and were similar or higher than previous cases. By excluding other causes of hypersensitivity pneumonitis, we concluded that the disease developed from exposure to microbial antigens in the metal working fluid.
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Citations
Citations to this article as recorded by  - Green manufacturing—performance of a biodegradable cutting fluid
Rahul Katna, Kanwarjeet Singh, Narayan Agrawal, Swati Jain
Materials and Manufacturing Processes.2017; 32(13): 1522. CrossRef - Association of Exposure to Chemicals with Dyspnea among Employed Workers: Analysis of the 3rdKorean Working Conditions Survey
Moon-Young Park, Sung-Ho Hwang, Kimyong Hong, Se-Eun Oh, Kyoung-Mu Lee
Journal of Korean Society of Occupational and Environmental Hygiene.2016; 26(1): 64. CrossRef - Microbial Assessment in Metal-Working Fluids Handling Industry
Hyunhee Park, Dongjin Park, Hae Dong Park
Journal of Korean Society of Occupational and Environmental Hygiene.2014; 24(3): 300. CrossRef - Microbial Exposure Assessment in Sawmill, Livestock Feed Industry, and Metal Working Fluids Handling Industry
Hyunhee Park, Haedong Park, Inseop Lee
Safety and Health at Work.2010; 1(2): 183. CrossRef
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Heart Rate Variability of Carbon Disulfide Poisoned Subjects after Exposure Cessation
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Sang Yoon Lee, Sung Il Cho, Do Myung Paek, Chang Bum Byeon, Mi Jeong Kim, Kyung Keun Park, Sang Hyeok Yim, Kil Seung Yang, Chang Kook Hwang, Hyung Joon Jhun
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Korean Journal of Occupational and Environmental Medicine 2006;18(2):123-129. Published online June 30, 2006
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DOI: https://doi.org/10.35371/kjoem.2006.18.2.123
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Abstract
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- OBJECTIVES
A previous study conducted in 2000 measuring the heart rate variability (HRV) of carbon disulfide (CS2)-poisoned subjects suggested that their HRV was reduced after exposure cessation. However, the study was limited by the following procedural limitations: (1) only 71 CS2-poisoned subjects participated, (2) no females participated, and (3) the CS2-poisoned subjects were older than the controls. This study was therefore conducted to overcome these limitations of the earlier study.
METHODS
The study subjects comprised 122 retired workers with CS2 poisoning and the same number of age- and sex-matched controls. Information on individual age, sex, height, weight, smoking history, alcohol drinking, regular exercise, medical and occupational history, chest x-ray, and ECG recording of the two groups was collected though a self-administered questionnaire and a medical examination. Standard Deviation of NN intervals (SDNN), Root-Mean-Square of Successive Differences (RMSSD), Total Power (TP), Low Frequency (LF), High Frequency (HF), and LF/HF ratio were measured as HRV indices for 5 minutes in the sitting position.
RESULTS
Univariate analysis revealed that all HRV indices of CS2-poisoned subjects were lower than those of the controls. Multiple linear regression analysis showed that CS2 poisoning had negative association with all HRV indices and that its association with RMSSD was statistically significant (P<0.05).
CONCLUSIONS
This study suggests that CS2-poisoned subjects continue to have reduced HRV, even though the exposure has ceased.
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