Annals of Occupational and Environmental Medicine

Work-Relatedness of Occupational Contact Dermatitis in a Tire Factory: Sora Choi, Han Soo Song, Chul Gab Lee; Korean Journal of Occupational and Environmental Medicine 2009;21(4):354-364. Published online December 31, 2009; DOI: https://doi.org/10.35371/kjoem.2009.21.4.354

Abstract PDF: OBJECTIVES
This study investigated occupational contact dermatitis in a tire factory, prompted by a long history of complaints of skin ailments by the factory workers.
METHODS
Participants (n=160) completed a questionnaire concerning job characteristics and skin symptoms, and received a medical examination. Fifty-four workers with suspected work-related contact dermatitis were chosen for a patch test of contact-related dermatitis.
RESULTS
The most frequent positive reactions of patch test were produced by diphenylguanidine, formaldehyde and cobalt. Twenty-one of the 54 individuals (38.9%) were judged to have work-related skin disease.
CONCLUSIONS
Exposure to natural and synthetic rubbers and additive materials pose a risk of contact dermatitis in a tire manufacturing environment. Improved sanitary work practices and public health awareness measures are suggested.

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A Case of Allergic Contact Dermatitis Caused by Epichlorohydrin and tris-DMP in an Epoxy Resin Worker: Min Kim, Daehwan Kim, Seonwook Hwang, Juhong Park, Chunhui Seo, Seunghwan Shin, Jinhong Ahn, Jongtae Lee; Korean Journal of Occupational and Environmental Medicine 2009;21(3):276-282. Published online September 30, 2009; DOI: https://doi.org/10.35371/kjoem.2009.21.3.276

BACKGROUND
Epoxy resin compounds are one of the common causes of occupational allergic contact dermatitis. In Korea, most cases of allergic contact dermatitis from epoxy resin compounds have been caused by the epoxy resin itself. We report a rare case of allergic contact dermatitis which was caused by epichlorohydrin, an ingredient of epoxy resin and 2,4,6-tris-(dimethylaminomethyl)phenol (tris-DMP), a kind of hardeners.
CASE
REPORT: A 43-year-old man, who had worked at the epoxy resin glue manufacturing factory since 1999, presented with mild and intermittent erythematous papules and rashes on his face, neck, trunk, and both arms. He was dealing with epoxy resin, epichlorohydrin, bisphenol A and hardeners. After a new hardener was added in August 2008, his skin lesions worsened from what he had experienced in the past. A skin patch test was performed to identify the causative chemicals of the skin lesion. Epichlorohydrin and tris-DMP elicited positive reactions after 48 hours and increased after 96 hours.
CONCLUSION
This case confirmed occupational allergic contact dermatitis caused by epichlorohydrin and tris-DMP, an ingredient of epoxy resin and a hardener, respectively.

Citations

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A systematic review of pure metals reinforced plastic composites
Adewale George Adeniyi, Joshua O. Ighalo
Iranian Polymer Journal.2021; 30(7): 751. CrossRef
Occupational Skin Diseases in Korea
Yeon-Soon Ahn, Min-Gi Kim
Journal of Korean Medical Science.2010; 25(Suppl): S46. CrossRef

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Investigation of Occupational Dermatological Problem with Additives in Polypropylene Manufacturing Process: Seung Ho Jeon, Kyong Min Lee, Kan Woo Yoon, Do Myung Paek, Jong Yeop Yoo, Hee Chul Eun; Korean Journal of Occupational and Environmental Medicine 2003;15(3):252-260. Published online September 30, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.3.252

Abstract PDF: OBJECTIVES
To investigate the causative agents for the dermatological problems associated with the polypropylene manufacturing process.
METHODS
The study subjects consisted of 44 male workers involved in the polypropylene manufacturing process. Twenty-seven of them had been exposed to additives, and the remaining 17 had not. Among the 27 exposed, 10 had been exposed previously, and 17 are currently being exposed through their duties. Patch test were performed with three different concentrations, 0.1%, 1% and 10% of 10 different additives that was diluted with Vaseline.
RESULTS
18 subjects (41%) had positive reactions to the patch tests. Exposed group had a higher reaction rate (51.9%) than the control group (23.5%). When the positive reactions were further classified, 7, 6 and 5 were compatible with probably irritant, probably allergic, and multiple hypersensitivity reactions respectively. The most frequent reactions were from Ultranox-626 followed by Millad 3988, Armoslip-E and Songstab Sc-100.
CONCLUSIONS
When considering the significantly higher probability of an allergic reaction rate among the currently exposed group compared to non- or previously-exposed groups, the nature of dermatological problems in a polypropylene plant is probably allergic. Ultranox-626, Millad3988, Armoslip-E and Songstab Sc-100 were the main causatives agents found in the process.

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Occupational Contact Dermatitis in Patch Test Clinics of General Hospitals: Hee Chul Eun, Bong Koo Lee, Kea Jeung Kim, Hyung Jai Kang; Korean Journal of Occupational and Environmental Medicine 1989;1(2):160-167. Published online November 30, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.2.160

Abstract PDF

Occupational allergic contact dermatitis cases who had visited the patch test clinics of Seoul National University Hospital(1984-1988) and Koryo General Hospital(1982-1988) were analyzed in this study. Patch test was performed with either Hollister-Stier standard battery or European standard battery in addition to the patients own materials and other commercially available antigens. Patch test was peformed according to the recommendation of International Contact Dermatitis Research Group. The result is summarized as follows. 1. Out of 946 cases 65 (6.9%) were suspected as having occupational dermatoses clinically and 35 (3.7%) were diagnosed as occupational allergic contact dermtitis after patch test. 2. Sixteen (45.7%) out of the 35 patients were male and 19 (54.3%) were female. Twenty one (60.0%) patients were in the age of 20 to 40 years. 3. The occupational distribution of 35 patients were medical personnels (8), cement workers (7), industrial workers (5), hair dressers (5), farmers (3), merchants (3), cooks (2) and painters (2). 4. Potassium dichromate, nickel sulfate and rubber chemicals were the most common occupational allergens. We also reviewed the Korean literatures related to the occupational dermatoses.

Citations

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Allergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report
Jae Hyuk Kim, Hyun Joon Kim, Sun Woong Kim
BMC Ophthalmology.2019;[Epub] CrossRef

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