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Original Article
The relationship between shift work pattern and thyroid stimulating hormone in female workers
Hun Jeong, Chang Ho Chae, Jun Ho Lee, Hyo Won Chong
Ann Occup Environ Med 2023;35:e14.   Published online June 22, 2023
DOI: https://doi.org/10.35371/aoem.2023.35.e14
AbstractAbstract AbstractAbstract in Korean PDFPubReaderePub
Background

Shift work is known to cause changes in the circadian rhythm of the human body and adversely affect not only physical health but also mental health. Some studies have demonstrated the correlation between shift work and thyroid stimulating hormone (TSH), a hormone that changes according to the diurnal rhythm, but few studies have reported the different TSH levels according to the shift work type. This study aimed to investigate changes in TSH according to the shift work type.

Methods

This study included 1,318 female workers who had a medical checkup at a university hospital in Changwon from 2015 to 2019. Shift work types were classified as non-shift work, regular 2 shifts, and irregular three shifts, and a TSH ≥ 4.2 mIU/L was defined as abnormal. A general linear model (GLM) was used to compare the TSH levels and the risk of subclinical hypothyroidism in each year, and a binary logistic analysis was performed using a generalized estimation equation (GEE) to compare the risk of subclinical hypothyroidism over the 5-year period.

Results

Of the 1,318 participants included in this study, 363, 711, and 244 were non-shift, two-shift, and irregular three-shift workers, respectively. In the GEE analysis, after adjusting for age, body mass index, smoking, and alcohol consumption, the odds ratios (ORs) were 1.81 (95% confidence interval [CI]: 1.15–2.86; p = 0.011) in 2 shifts and 2.02 (95% CI: 1.23–3.32; p = 0.006) in irregular three shifts, compared to non-shift.

Conclusions

Our results showed that shift work had a higher risk of subclinical hypothyroidism than non-shift work and that there was a significant difference in the risk of subclinical hypothyroidism according to the shift work type. These findings suggest that the shift work type can be considered in future thyroid function tests and evaluations.

여성근로자에서 교대근무유형과 갑상선 자극 호르몬과의 연관성
목적
교대근무는 인체의 일중리듬에 변화를 일으키고 심혈관 질환, 소화기 질환 및 대사증후군과 같은 신체적 건강 뿐만 아니라 수면장애, 우울감 등을 포함한 정신건강에도 유해한 영향을 끼치는 것으로 알려져 있다. 일중리듬에 의해 변화하는 호르몬 중 하나인 갑상선 자극 호르몬(TSH)의 농도가 교대근무와의 연관성을 보여주는 연구들이 있으나 교대근무 유형에 따른 차이를 살펴본 연구는 부족한 실정이다. 본 연구는 교대근무의 유형에 따른 TSH의 변화를 알아보고자 하였다.
방법
2015년부터 2019년까지 창원의 일개 대학병원의 건강진단을 받은 1,318명의 여성근로자를 대상으로 연구를 진행하였다. 교대근무유형은 비교대근무, 규칙적 2교대 및 불규칙 3교대로 분류하였으며 TSH ≥ 4.2mIU/L인 경우 이상이 있는 것으로 정의하였다. 연도별로 TSH의 농도를 비교하기 위하여 일반선형모델을 사용하였으며 5년간의 불현성 갑상선기능저하증의 위험도를 비교하기 위하여 일반화추정방정식을 사용하여 이분형 로지스틱 분석을 시행하였다.
결과
연구 대상자 1,318명 중 비교대근무자는 총 363명, 2교대 근무자는 총 711명, 불규칙 3교대 근무자는 총 244명이었다. 연령, 체질량지수(BMI), 흡연, 음주를 보정하고 일반화추정방정식을 사용하여 이분형 로지스틱 분석을 시행한 결과, 비교대근무자를 기준으로 하였을 때, OR은 2교대 근무자에서 1.81(95% CI 1.15-2.86, P=0.011), 불규칙 3교대 근무자에서 2.02(95% CI 1.23-3.32, P=0.006)로 나왔다.
결론
본 연구의 결과는 교대근무가 비교대근무에 비해 불현성 갑상선기능저하증의 위험도가 높았으며 교대근무의 유형에 따른 불현성 갑상선기능저하증의 위험도에 있어 유의미한 차이를 보였다. 이는 이전 연구들의 결과를 뒷받침할 뿐만 아니라 향후 갑상선 기능 검사 및 평가에 있어 교대근무의 유형이 고려대상이 될 수 있을 것으로 생각된다.
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Original Article
Association between split shift work and work-related injury and disease absence
Kwon Ko, Jae Bum Park, Kyung-Jong Lee, Inchul Jeong
Ann Occup Environ Med 2021;33:e27.   Published online August 19, 2021
DOI: https://doi.org/10.35371/aoem.2021.33.e27
AbstractAbstract PDFSupplementary MaterialPubReaderePub
Background

Shift work (particularly split shifts) has been noted among the working conditions that hinder sustainable work. However, little is known regarding the effects of split shifts on health. This study aimed to investigate the association between split shift work and work-related injury and disease absence.

Methods

This study used data from the fifth Korean Working Conditions Survey and included 4,042 paid shift workers. Shift work type and self-reported work-related injury and disease absence were investigated using a questionnaire. Logistic regression analysis was performed to investigate the association between split shift work and work-related absence with rotating shift worker as the reference group.

Results

Of the 4,042 shift workers, 980 (24.3%) were split shift workers. The adjusted odds ratio (aOR) of split shift for absence due to work-related injury was high at 2.94 (95% confidence interval [CI]: 1.85–4.68) and the aOR of split shift for absence due to work-related disease was also high at 1.58 (95% CI: 1.09–2.29) compared to rotating shift.

Conclusions

Split shift work leads to an increased risk of absences due to work-related injury and disease.


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Research Article
Association between sleep duration and impaired fasting glucose according to work type in non-regular workers: data from the first and second year (2016, 2017) of the 7th Korean National Health and Nutrition Examination (KNHANE) (a cross-sectional study)
JaeHan Joo, Jae-Gwang Lee, SangWoo Kim, JaeHan Lee, June-Hee Lee, Kyung-Jae Lee
Ann Occup Environ Med 2020;32:e29.   Published online July 30, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e29
AbstractAbstract PDFPubReaderePub
Background

We aimed to find the relationship between sleep duration and impaired fasting glucose according to working type in non-regular workers using the 2016 and 2017 Korean National Health And Nutrition Examination (KNHANE, 7th revision).

Method

In the 1st and 2nd year (2016, 2017) of the 7th KNHANE, 16,277 people participated. Minors were excluded because this study was intended for individuals aged 19 years and older. As this study was based on wage workers, unemployment, self-employed workers, employers, unpaid family workers, and those who have insufficient answers such as unknown or no response were excluded. Regular workers were excluded because this study was intended for non-regular workers. Finally, a total of 2,168 people were included in the survey, except those who had been diagnosed with diabetes, had a fasting blood glucose level of 126 mg/dL or higher, or taking hypoglycemic agents or receiving insulin injections. To find the relationship between sleep duration and impaired fasting glucose according to work type in non-regular workers, multiple logistic regression analysis was performed by adjusting the general and occupational characteristics after stratification according to work type. All statistical analyses were performed using the SPSS software (version 26.0; SPSS Inc., Chicago, IL, USA).

Results

In the case of insufficient sleep duration in irregular female workers, the odds ratio (OR) of impaired fasting glucose was statistically insignificant, but in the case of insufficient sleep duration in irregular male workers who have shift work, the odds ratio (OR) of impaired fasting glucose was significantly higher than that of sufficient sleep duration (Model 1, OR: 3.05, 95% confidence interval [CI]: 1.18–7.90; Model 2, OR: 2.81, 95% CI: 1.08–7.29).

Conclusions

Our findings demonstrate that insufficient sleep duration was associated with an increase in fasting blood glucose levels in non-regular male workers working shifts. This means that non-regular workers are in desperate need for adequate sleep and health care. We hope that our study will help improve the health of non-regular workers and more systematic and prospective follow-up studies will be conducted to further improve the health of non-regular workers.


Citations

Citations to this article as recorded by  
  • The Impact of Night Work on the Sleep and Health of Medical Staff—A Review of the Latest Scientific Reports
    Katarzyna Czyż-Szypenbejl, Wioletta Mędrzycka-Dąbrowska
    Journal of Clinical Medicine.2024; 13(15): 4505.     CrossRef
  • Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China
    Yang Zhao, Xunhao Lu, Yanghua Wang, Yiyi Cheng, Qiao He, Rongqi Qin, Wenrui Li, Haizhou Liu, Yuanfang Liu
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Unraveling the associations and causalities between glucose metabolism and multiple sleep traits
    Minhan Yi, Quanming Fei, Ziliang Chen, Wangcheng Zhao, Kun Liu, Shijie Jian, Bin Liu, Meng He, Xiaoli Su, Yuan Zhang
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Nutritional Biomarkers and Factors Correlated with Poor Sleep Status among Young Females: A Case-Control Study
    Sara AL-Musharaf, Lama AlAjllan, Ghadeer Aljuraiban, Munirah AlSuhaibani, Noura Alafif, Syed Danish Hussain
    Nutrients.2022; 14(14): 2898.     CrossRef
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