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2 "Susceptibility"
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Original Article
Wrist Ratio as a Risk Factor of Carpal Tunnel Syndrome
Duck Soo Kim, Hae Kwan Cheong, Yong Wook Kwon
Korean Journal of Occupational and Environmental Medicine 2001;13(3):242-252.   Published online September 30, 2001
DOI: https://doi.org/10.35371/kjoem.2001.13.3.242
AbstractAbstract PDF
OBJECTIVES
To evaluate the risk factors of the carpal tunnel syndrome (CTS) and the impact of the wrist ratio on the prevalence of CTS in workers on repetitive work over a long term.
METHODS
Study subjects consisted of 45 male and 16 female workers in a company that produces soundproof material in Gyeongju. We conducted a physical examination, a self-reported questionnaire survey and a nerve conduction study. CTS cases were defined as those subjects that had a positive finding in both the nerve conduction study and the physical examination done by a doctor specializing in rehabilitation medicine.
RESULTS
Prevalence of CTS among the study subjects was 26.2/100 persons. The prevalence of CTS was positively associated with increasing age (p<0.01, using the chi-square test for trend) and female gender (OR=6.98, 95% CI=1.66-31.0), but was negatively associated with the educational level (p<0.01 by the chi-square for trend). Workers in the production area had a higher prevalence of CTS compared to those in the clerical area (OR=10.8 in the frame manufacturing process, OR=32.2 in the vacuum molding process). Patients with CTS had a narrower mean wrist width and a shorter mean hand and palm length, compared to those that had no disease (p<0.01 by the Student's t-test). The number of subjects who had a wrist ratio of 0.74 or more was significantly higher in cases of CTS (OR=4.0, 95% CI=1.01-16.3). However, a multiple logistic regression analysis showed only that the type of work was a significant variable after adjusting for the other variables.
CONCLUSIONS
The wrist ratio, a surrogate of carpal tunnel configuration, can represent individual susceptibility to CTS. However this study shows that the use of the wrist ratio for predicting CTS risk is not adequate. The development of a new carpal tunnel configuration index based on more direct measurements of the tunnel shape will provide a better predictor of individual susceptibility to CTS.

Citations

Citations to this article as recorded by  
  • Distribution of age, gender, and occupation among individuals with carpal tunnel syndrome based on the National Health Insurance data and National Employment Insurance data
    Il-Ho Lee, Young-Ki Kim, Dong-Mug Kang, Se-Yeong Kim, In-Ah Kim, Eun-Mi Kim
    Annals of Occupational and Environmental Medicine.2019;[Epub]     CrossRef
  • A comparison of carpal tunnel syndrome between digital and paper textbook users in elementary schools
    GyeongAe Seomun, Sung-Bom Pyun, Jung-Ah Lee, Eun-Jung Kim, Wonjung Noh
    Work.2016; 53(4): 909.     CrossRef
  • Factors Influencing on Fatigue in Operating Room Nurses
    Eun-Seon Lee, In-Sook Kim
    Korean Journal of Occupational Health Nursing.2012; 21(3): 229.     CrossRef
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Original Article
Biomarkers of Susceptibility in Bladder Carcinogenesis
Sue Kyung Park, Hae Won Jung, Dae Hee Kang, Keun Young Yoo, Soo Hun Cho
Korean Journal of Occupational and Environmental Medicine 1997;9(2):341-356.   Published online June 30, 1997
DOI: https://doi.org/10.35371/kjoem.1997.9.2.341
AbstractAbstract PDF
Owing to the development of molecular biological techniques to identify new biomarkers of bladder cancer, the information obtained from the studios in which newly developed biomarkers are applied potentially useful in screening of general population, diagnosis of patients, predicting biological behavior and prognosis, and exposure assessments. Despite of rapid development there are a few review about the biomarkers in bladder cancer from which grogs summary of results as well as their optimal function can be considered. This study was carried out in biomarkers of bladder cancer by reviewing the literature to assess the usefulness and stapes of researches for biomarkers of bladder cancer on high risk groups, general population and patients. The biomarkers of bladder cancer were classified by Weinstein's model of carcinogenesis, simple classification of exposure-discase in classical epidemiology, classification by conception of exposure-disease continuum on molecular epidemiology, and application of biomarkers. Two biomarkers, N-acetylation enzyme and Glutathion S-transferase, which had been studied extensively in molecular epidemiology were selected and reviewed. Although the generalization, prediction and diagnosis of bladder cancer based on a single biomarker give rise to trouble due to intravariation of bladder tumor and heterogeneity of biomarkers variation, searching for more specific tumor markers may accurately lead better prediction of prognosis and better estimation of treatment response. The usefulness of both N-acetylation enzyme and glutathion 5-transferase in high-risk groups who have exposes to carcinogen may be more valuable. However more informations are neede in order to apply these biomarkers in clinical practices in further studies.

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