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Case Report
Gastric and rectal cancers in workers exposed to asbestos: a case series
Byeong Ju Choi, Saerom Lee, Iu Jin Lee, Soon Woo Park, Sanggil Lee
Ann Occup Environ Med 2020;32:e4.   Published online January 2, 2020
DOI: https://doi.org/10.35371/aoem.2020.32.e4
AbstractAbstract PDFPubReaderePub
Background

The Occupational Safety and Health Research Institute (OSHRI) of the Korea had not recognized gastrointestinal cancer as work-related disease during their evaluation. However, in 2018 OSHRI recognized gastric and rectal cancers as work-related disease in asbestos-exposed workers. We present 2 such cases along supportive evidence of causation.

Case presentation

Patient A: A 57-year-old man had worked for about 40 years since 1978 as an oxygen cutter at workplaces that dismantle ships, buildings, boilers, and thermal power plants. In November 2016, endoscopy and biopsy confirmed the diagnosis of advanced gastric cancer, for which he underwent subtotal gastrectomy and chemotherapy; however, he later died of the cancer. Patient B: A 71-year-old man had worked in shipbuilding and repair workplaces for approximately 49 years, being employed in pipe laying, asbestos insulation installation, grinding, and other ship repair work. In 2003, he was diagnosed of rectal cancer by abdominal computed tomography. He accordingly underwent surgical removal of the cancer. Based on the occupational history of the 2 patients and our review of the relevant literature addressing the occupational environment, we concluded that both patients had continuous exposure to high levels of asbestos while performing their jobs for 40 and 49 years, respectively.

Conclusion

Both patients had a history of smoking and drinking (non-occupational personal risk factors). However, the possibility of an increased risk of gastric and rectal cancers from asbestos exposure cannot be excluded. Therefore, we considered that occupational exposure to asbestos had contributed to the cancer diagnosis in these cases. Workers exposed to asbestos should be made aware of the possibility of gastric or rectal cancer, and should undergo monitoring and medical examinations. Appropriate compensation for gastric and rectal cancers that occur in workers exposed to asbestos are anticipated in future.


Citations

Citations to this article as recorded by  
  • Sustainable management of hazardous asbestos-containing materials: Containment, stabilization and inertization
    Shiv Bolan, Leela Kempton, Timothy McCarthy, Hasintha Wijesekara, Udara Piyathilake, Tahereh Jasemizad, Lokesh P. Padhye, Tao Zhang, Jörg Rinklebe, Hailong Wang, M.B. Kirkham, Kadambot H.M. Siddique, Nanthi Bolan
    Science of The Total Environment.2023; 881: 163456.     CrossRef
  • Parkinson's disease in a worker exposed to insecticides at a greenhouse
    Yangwoo Kim, Inah Kim, Jung-Min Sung, Jaechul Song
    Annals of Occupational and Environmental Medicine.2021;[Epub]     CrossRef
  • Increased Risk of Gastric Cancer in Asbestos-Exposed Workers: A Retrospective Cohort Study Based on Taiwan Cancer Registry 1980–2015
    Yi-Jen Fang, Hung-Yi Chuang, Chih-Hong Pan, Yu-Yin Chang, Yawen Cheng, Lukas Jyuhn-Hsiarn Lee, Jung-Der Wang
    International Journal of Environmental Research and Public Health.2021; 18(14): 7521.     CrossRef
  • Assessing Energy-Based CO2 Emission and Workers’ Health Risks at the Shipbreaking Industries in Bangladesh
    Nandita Mitra, Shihab Ahmad Shahriar, Nurunnaher Lovely, Md Shohel Khan, Aweng Eh Rak, S. P. Kar, Md Abdul Khaleque, Mohamad Faiz Mohd Amin, Imrul Kayes, Mohammed Abdus Salam
    Environments.2020; 7(5): 35.     CrossRef
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  • 4 Web of Science
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Case Report
Work-related olfactory disorder: a case series and review
Soon Woo Park, Young Joong Kang, Huisu Eom, Hyun-Jin Cho, Jungho Ahn, Sang-Gil Lee
Ann Occup Environ Med 2018;30:18.   Published online March 12, 2018
DOI: https://doi.org/10.1186/s40557-018-0230-3
AbstractAbstract PDFPubReaderePub
Background

The olfactory bulb is anatomically exposed and thus can be directly damaged by external stimulation. This can occur as an occupational injury owing to contact with organic solvents or other causes. We present cases of eight patients who sustained occupation-related exposure to potentially toxic substances and later presented with signs and symptoms of anosmia. We examined the occupational and medical characteristics of the patients and evaluated their work-relatedness.

Case presentation

Case 1: A 50-year-old man performed high-frequency heat treatments for approximately 11 years. He experienced decreased senses for olfaction and taste during the later years culminating in the diagnosis of anosmia after 3 years (high work-relatedness). Case 2: A 54-year-old man whose work involved exposure to various organic solvents, such as spray painting and application of paint and thinners for approximately 4 years, was subsequently diagnosed with anosmia based on rhinorrhea, headache, and loss of olfaction (high work-relatedness). Case 3: A 44-year-old-man who performed spray painting for approximately 17 years developed anosmia (high work-relatedness). Case 4: A 44-year-old man was involved in ship engine cleaning once a month, for approximately 7 h per cleaning session; he was diagnosed with anosmia based on loss of olfaction (low work-relatedness). Case 5: A 41-year-old man worked in ship building block construction for approximately 13 years; anosmia diagnosis was based on loss of olfaction (low work-relatedness). Case 6: A 47-year-old woman performed product inspection and labeling at a plant manufacturing automobile parts; anosmia diagnosis was based on decreased olfaction and taste (low work-relatedness). Case 7: A 50-year-old woman performed epoxy coating in a plant manufacturing automobile parts; anosmia diagnosis was based on diminishing olfaction (low work-relatedness). Case 8: A 57-year-old woman performed cleaning of the area where mobile phone parts were manufactured; anosmia diagnosis was based on diminishing olfaction (low work-relatedness).

Conclusion

The study results confirmed work-relatedness when the subject was young, and the duration of exposure was long without any other cause of anosmia. Regarding compensation for occupational diseases, work-relatedness can be recognized as a relative concept.


Citations

Citations to this article as recorded by  
  • Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study
    Ingrid Ekström, Maria Larsson, Debora Rizzuto, Johan Fastbom, Lars Bäckman, Erika J Laukka, Anne B Newman
    The Journals of Gerontology: Series A.2020; 75(12): 2441.     CrossRef
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Research Article
Effectiveness of workers’ general health examination in Korea by health examination period and compliance: retrospective cohort study using nationwide data
Huisu Eom, Jun-Pyo Myong, Eun-A Kim, Bohwa Choi, Soon Woo Park, Young Joong Kang
Ann Occup Environ Med 2017;29:2.   Published online February 17, 2017
DOI: https://doi.org/10.1186/s40557-017-0160-5
AbstractAbstract PDFPubReaderePub
Background

Our study evaluated the effectiveness of the Workers’ General Health Examination by health examination period and compliance.

Methods

A retrospective cohort of the health examination participants in 2006 (baseline year: N = 6,527,045) was used. We identified newly occurring cardio-cerebrovascular disease over 7 years (from 2007 to 2013). After stratification by age, sex, and national health insurance type, we identified 7 years’ cumulative incidence of cardio-cerebrovascular disease by health examination compliance and estimated its relative risk by health examination period and compliance.

Results

The compliant group presented a lower cumulative incidence of cardio-cerebrovascular disease than the non-compliant group; this result was consistent across sex, working age (40s and 50s), and workplace policyholder. Relative risk of cardio-cerebrovascular disease by health examination period (1 and 2 years) showed statistically significant results in ischemic heart disease for male participants. Of men in their 40s, office workers (over a 2-year period) presented statistically higher relative risk of ischemic heart disease than non-office workers (over a 1-year period: 1.03; 95% confidence interval, 1.02–1.03). However, there were no consistent results in ischemic cerebrovascular disease and hemorrhagic cerebrovascular disease for men or cardio-cerebrovascular disease for women.

Conclusion

A 1-year period of Workers’ General Health Examinations in non-office workers had a more significant prevention effect on ischemic heart disease than a 2-year period in office workers among working age (40s–50s) men. It is, however, necessary to consider that prevention of cardio-cerebrovascular disease can be partially explained by their occupational characteristics rather than by health examination period.


Citations

Citations to this article as recorded by  
  • Investigating and prioritizing of the barriers of performing periodic occupational examinations in industries of Kashan city in 2019
    Marzieh Sadaf, MasoudMotalebi Kashani, HamidReza Saberi, Hossein Akbari, SedigheDehghani Bidgoli, Mitra Hannani
    International Archives of Health Sciences.2021; 8(2): 122.     CrossRef
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Case Report
A Case of Heat Stroke in an Aluminium Utensil Plant
Soon Woo Park, You Lee Cho, Dong Ho Oh, Jung Yon Choe, Hae Ri Jun
Korean Journal of Occupational and Environmental Medicine 1999;11(2):293-303.   Published online June 30, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.2.293
AbstractAbstract PDF
An 18-year-old man suffered heat stroke after continuous working for 26 hours on his first day in an aluminium utensil plant in August 1998. His job was to put a pressed aluminium utensil on the conveyer before the process of spray painting. The ranges of temperature and relative humidity measured at the local weather-station during the patient' s working period were 23.6-30.2 degrees C, 49-87 % respectively. On arrival the patient was comatose and suffered generalized seizure three times. His rectal temperature was 41.2 degrees C . blood pressure was 90/60 mmHg, pulse was 148 beats/minute and respiratory rate was 28 times/minute. The serum level of AST was 421 IU/L. ALT was 205 IU/L, LDH was 1,160 IU/L. myoglobin was higher than 500 ng/mL. OK was higher than 2,000 IU/L. He recovered consciousness 7th day of admission and discharged after 2 months but cerebellar dysarthria was remained. The patient felt himself several prodromal symptoms of heat stroke and he showed awkward behavior considered to be drowsiness, but the patient and his co-workers neglected them. This case report shows that heat stroke can be occurred in a condition that ambient temperature, humidity, and working load are not extreme. A thorough health education and management concerned with guidelines on salt and water intake, detection of early symptoms of heat-related illness, prompt body cooling and rapid transportation to a hospital is necessary.

Citations

Citations to this article as recorded by  
  • Factors affecting heat-related diseases in outdoor workers exposed to extreme heat
    Jungsun Park, Yangho Kim, Inbo Oh
    Annals of Occupational and Environmental Medicine.2017;[Epub]     CrossRef
  • Occupational Diseases in Korea
    Seong-Kyu Kang, Eun A Kim
    Journal of Korean Medical Science.2010; 25(Suppl): S4.     CrossRef
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Original Article
Variation in Patient Days and Medical Care Benefits Among Finger-Amputated Industrial Injuries
Jong Ho Lee, Sin Kam, Keon Yeop Kim, Young Sook Lee, Yune Sik Kang, Young Ae Ha, Ji Yeon Son, Soon Woo Park, Jong Young Lee
Korean Journal of Occupational and Environmental Medicine 1997;9(3):439-451.   Published online October 31, 1997
DOI: https://doi.org/10.35371/kjoem.1997.9.3.439
AbstractAbstract PDF
No abstract available.

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Original Article
Development of Korean Computerized Neurobehavioral Tests arid Evaluation of Applicability
Jong Young Lee, Sang Soong Nam, Chae Yong Lee, Sung Ah Kim, Ju Young Lee, Soon Woo Park, Ji Yeon Son
Korean Journal of Occupational and Environmental Medicine 1996;8(3):546-559.   Published online December 31, 1996
DOI: https://doi.org/10.35371/kjoem.1996.8.3.546
AbstractAbstract PDF
We tried to develop Korean computerized neurobehavioral tests to promote neurobehavioral research and screening in occupational setting in Korea. This program was designated Neurobehavioral Tests for Occupational Screening (NTOS). NTOS consisted of 3 test items, choice reaction time (2 choice and 4 choice), simple reaction time (visual and auditory stimulus), finger tapping test (both hands). NTOS was administered to 120 students of medical school and to evaluate applicability. The results of reaction time tests was positively skewed but finger tapping test was negatively skewed. The only data that was not skewed was the mean frequency of finger tapping of dominant hand. The means and standard deviations of choice reaction time were 429.7 msec and 109.8 msec (2 choice), 493. 6 msec and 92.0 msec (4 choice). The results of simple reaction time were 254 msec (mean) and 55 msec (standard deviation). The mean frequency of finger tapping of dominant hand was 77.2 and that of nondominant hand was 64.9. The results of 2 choice reaction time test and finger tapping of dominant hand showed statistically significant sex difference. Factor analysis showed 2 factors, 1st reaction tests and 2nd tapping. The mean frequency of finger tapping had negative weak correlation with other reaction time test results. This computerized neurobehavioral tests may be widely applied in the other future studies, and is to be improved for the practical purpose of the occupational neurotoxico-logical area.

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Original Article
Effects of Number and Method of Visual Stimuli on Simple Reaction Time
Jee Sung Kim, Sung Ah Kim, Chae Yong Lee, Soon Woo Park, Si Hyun Nam, Jong Young Lee, Ji Yeon Son
Korean Journal of Occupational and Environmental Medicine 1996;8(3):477-489.   Published online December 31, 1996
DOI: https://doi.org/10.35371/kjoem.1996.8.3.477
AbstractAbstract PDF
In. order to evaluate the effects of number and method of visual stimuli on simple reaction time and determine the proper number of trials, simple reaction time of the computerized test of NTOS (Neurobehavioral Test for Occupational Screening) was carried out on 240 medical students. The prominent difference was found between male and female on simple reaction time. Regarding the effect of number based on the parameters of measures and the purpose of test itself, 64 trials was considered as proper number. The mean reaction time was different according to the methods of visual stimuli, such as color and size(p<0.05). The larger and more intence visual stimuli were, the faster sim-ple reaction time was. In respect to sex, that difference was similar. But, there was no difference depending upon whether the each result of each trial was showed on the monitor. The subjects, however, showed much interest when the result showed. Further studies, including the various variables on visual stimuli, are required to compare among various studies.

Citations

Citations to this article as recorded by  
  • Performance assessment on the Korean Computerized Neurobehavioral Test using a mobile device and a conventional computer: an experimental study
    Young Seok Byun, Sung Kyu Park, Joon Sakong, Man Joong Jeon
    Annals of Occupational and Environmental Medicine.2018;[Epub]     CrossRef
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Original Article
Weighted Needle Pinprick Sensory Threshold (WPT) and Arthropornetric Parameters
Jong Young Lee, Ji Yeon Son, Soon Woo Park, Eung Chun Lee, Doohie Kim
Korean Journal of Occupational and Environmental Medicine 1994;6(2):342-347.   Published online September 30, 1994
DOI: https://doi.org/10.35371/kjoem.1994.6.2.342
AbstractAbstract PDF
To assess the relationship of pinprick sensory threshold with height and weight, Ninety seven healthy young (age 19 to 28) males were tested on their anatomical snuff box of both Hands. Their WPT was measured by device holding and moving weighted needle sensory threshold apparatus. Mean of the WPT was 0.43(+/-0.24) g in left and, 0.53( 0.30) g in right hand. Difference of WPT between the right and left hand appeared statistically significant (p<0.01) . Correlation coefficient of WPT with height was 0.26461 (p<0.01) in left and, 0.31856 (p<0.01) in right hand. Weight was statistically significantly correlated with WPT in left hand (r=0.24932, p<0.01) The study shows that the left-right difference and influence of height in pinprick sense may exist in normal healthy male adults.

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Original Article
Complex effect of low blood lead and cadmium to plasma renin activity and blood pressure
Doo Hie Kim, Soon Woo Park, Duk Hee Lee, Bong Ki Jang, Sung Chul Hong, Dong Chan Kim
Korean Journal of Occupational and Environmental Medicine 1993;5(1):128-136.   Published online February 28, 1993
DOI: https://doi.org/10.35371/kjoem.1993.5.1.128
AbstractAbstract PDF
No abstract available.

Citations

Citations to this article as recorded by  
  • Pollutant levels in ambient air and blood in Korea
    Chan-Seok Moon, Masayuki Ikeda
    Environmental Health and Preventive Medicine.1996; 1(1): 33.     CrossRef
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Original Article
Byssinosis in carbon textile workers in Taegu, Korea
Doohie Kim, Soon Woo Park, Hong Hwan Kim, Kyeong Dong Chung, Duk Hee Lee, Sung Kwan Lee
Korean Journal of Occupational and Environmental Medicine 1991;3(2):177-184.   Published online November 30, 1991
DOI: https://doi.org/10.35371/kjoem.1991.3.2.177
AbstractAbstract PDF
No abstract available.

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