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4 "Screening test"
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Research Article
Application of cold intolerance symptom severity questionnaire among vibration-exposed workers as a screening tool for the early detection of hand-arm vibration syndrome: a cross-sectional study
A Ram Kim, Dae Yun Kim, Ji Soo Kim, Heun Lee, Joo Hyun Sung, Cheolin Yoo
Ann Occup Environ Med 2019;31:6.   Published online March 1, 2019
DOI: https://doi.org/10.1186/s40557-019-0284-x
AbstractAbstract PDFPubReaderePub
Background

The detection rate of hand-arm vibration syndrome (HAVS) is very low in South Korea compared with other countries. The absence of uniform consensus and guidelines for diagnosing HAVS has been presumed to be one of the reasons. The HAVS has various manifestations including cold intolerance and its severity can be measured using the cold intolerance symptom severity (CISS) questionnaire. This study aimed to determine whether the CISS questionnaire, being used as a screening tool, can aid in the early detection of HAVS.

Methods

A total of 76 male workers with vibration-induced symptoms were enrolled as the final study participants. To compare the CISS score of healthy individuals, 41 men who had never been exposed to local vibration were included in the study. In addition to the former medical questionnaire, the participants answered the CISS questionnaire. A statistical analysis was conducted to identify the association of CISS scores with vibration induced symptom and to determine its cut off value.

Results

The reliability of the CISS questionnaire was proven to be good, with a total Cronbach’s alpha of 0.922. The mean CISS score of the exposed group increased in every vascular stage [stage 0 = 42.6 (18.5); stage 1 = 59.4 (14.1); and over stage 2 = 60.2 (21.6)]. They were significantly higher than that of the non-exposed group. The result was fairly consistent with those in the sensorineural stage. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under curve (AUC) of 30 were 88.5, 65.3, 76.1, 82.1 and 0.769, respectively. From the result of logistic regression, the adjusted odds ratio of both components increased by the CISS score grouped by 30s.

Conclusions

The self-reported CISS questionnaire, used to measure the degree of cold intolerance, showed high agreement with the Stockholm classification of HAVS. Hence, we recommend the use of this questionnaire to assess the level of cold intolerance among vibration-exposed workers and detect individuals who are at risk of vibration-induced impairment with a cutoff value of 30.

Trial registration

IRB No. 2018–07–040-001. Registered on 4 September 2018.


Citations

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  • Multicenter Prospective Randomized Comparison of Ultrasound-Guided Stellate Ganglion Versus Thoracic Paravertebral Block for Sympathetic Blockade in Chronic Upper Extremity Pain
    Jeongsoo Kim, Joon Cha, Sheung Nyoung Choi, Gang Heo, Yongjae Yoo, Jee Youn Moon
    Anesthesia & Analgesia.2024;[Epub]     CrossRef
  • A Scoping Review on Occupational Noise Mitigation Strategies and Recommendations for Sustainable Ship Operations
    Kresna Febriyanto, Joana Cristina Cardoso Guedes, Luis João Rodrigues Das Neves Correia Mourão
    International Journal of Environmental Research and Public Health.2024; 21(7): 894.     CrossRef
  • Cold intolerance and hand-arm vibration syndrome
    Roger Anthony Cooke, Ian James Lawson
    Occupational Medicine.2022; 72(3): 152.     CrossRef
  • Botulinum Toxin Type A for Lumbar Sympathetic Ganglion Block in Complex Regional Pain Syndrome: A Randomized Trial
    Yongjae Yoo, Chang-Soon Lee, Jungsoo Kim, Dongwon Jo, Jee Youn Moon
    Anesthesiology.2022; 136(2): 314.     CrossRef
  • Hand-arm vibration management: an operational health and safety strategy framework
    David John Edwards, Igor Martek, Obuks Ejohwomu, Clinton Aigbavboa, M. Reza Hosseini
    International Journal of Building Pathology and Adaptation.2021; 39(5): 811.     CrossRef
  • Understanding and Measuring Long-Term Outcomes of Fingertip and Nail Bed Injuries and Treatments
    Kenneth R. Means, Rebecca J. Saunders
    Hand Clinics.2021; 37(1): 125.     CrossRef
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Original Article
Evaluation of Early Neurologic Abnormalities on the Workers Exposed to Acrylamide
Seong Soon Kim, Hae Kwan Cheong, Yong Wook Kwon
Korean Journal of Occupational and Environmental Medicine 2000;12(3):367-383.   Published online September 30, 2000
DOI: https://doi.org/10.35371/kjoem.2000.12.3.367
AbstractAbstract PDF
OBJECTIVES
Acrylamide is a neurotoxin inducing central-peripheral distal axonopathy. The authors evaluated several neurologic tests to screen the early effect of occupational acrylamide exposure.
METHODS
Fifty-two males working either in the production of acrylamide monomer or in the handling of acrylamide in Ulsan, Korea, were selected and subcategorized into the high-exposure group (n=10, mean age of 30. 4 years) and the low-exposure group (n=42, mean age of 28.9 years). Twenty-three males (mean age 29.4 years) from medical professionals and students were chosen as a non-exposed reference group. Symptom questionnaire, neurologic examination, electrodiagnostic test, vibrotactile threshold test, and Lanthony desaturated 15 panel test (LD-15D) were done.
RESULTS
The high-exposure group showed more number of specific symptoms on questionnaire and more abnormal two point discrimination test. High-exposure group showed a significant difference in the median motor conduction velocity, peroneal nerve motor latency, sensory amplitude of median nerve action potential, and sensory latency of sural nerve. The vibrotactile threshold of the high-exposure group was significantly higher in both hands and feet than that of the low-exposure group and the reference group. Average color confusion index on the LD-15D was significantly higher in the high-exposure group (median 22.7, range 0-135.7) than in the reference group (median 2.4, range 0-33.2).
CONCLUSIONS
The symptom questionnaire, vibrotactile threshold test, and color discrimination test are sensitive in detection of the early acrylamide-induced neuropathy, and the combination of these tests would further facilitate the effectiveness of the screening.

Citations

Citations to this article as recorded by  
  • Usefulness of Color Vision Test for Early Detection of Neurological Damages by Neurotoxic Substances
    Eun-Hee Lee, Kyungho Choi, Hong Jae Chae, Domyung Paek
    Journal of Preventive Medicine and Public Health.2008; 41(6): 397.     CrossRef
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  • 1 Crossref
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Original Article
Development of Methods to Estimate Exposure Levels to Vinyl Chloride Monomer and Multiphasic Screening Tests for Workers of Polyvinyl Chloride Manufacturing Factories
Heon Kim, Youn Jeong Nam, Sung Taek Kim, Dae Young Kim, Sul Hui Han, Kuck Tae Park
Korean Journal of Occupational and Environmental Medicine 1994;6(2):201-218.   Published online September 30, 1994
DOI: https://doi.org/10.35371/kjoem.1994.6.2.201
AbstractAbstract PDF
In order to develop questionnaire estimating vinyl chloride monomer(VCM) exposure levels, to reset selection criteria for detailed tests, to measure current VCM exposure levels, to evaluate the mutagenic effects of VCM exposures and to develop multiphasic screening method of PVC- or VCM-handling workers, VCM concentrations of work environments were measured and tentative self-administrative questionnaire, physical examination, sister chromatid exchange(SCE) test and some clinical chemical test were applied to 195 men who had been handling VCM or PVC(Exposed Group) and 37, in the same factories without exposure to VCM or in polyethylene- or polypropylene-related factories(Control Group). Mean VCM concentrations of work environments were 0.268+/-0.183 ppm under PVC synthesis processes, 0.160+/-0.200 ppm under VCM synthesis process, 0.076+/-0.111 ppm under PVC pipe producing processes, 0.090+/-0.108 ppm under PVC wall paper, sheet, or film producing processes, 0.071+/-0.051 ppm under PVC floor producing processes, 0.243+/-0.250 ppm under PVC sash producing processes, and 0.020+/-0.031 ppm under triming process. VCM levels of work environments under manual resin mixing processes (0.209+/-0.168 ppm)were higher than those of the others (0.209+/-0.168 ppm) (p-value<0.05). There was no VCM-related symptoms, the positive response rates of which were higher in the Exposed Group. Overall abnormal rate in clinical chemistry test of the Exposed Group was higher than that of the Control Group, but due to extermely low exposure level of exposure group and to small sample size of the Control Group, no statistical significance was found(p-value>0.05). SCE frequencies of the Exposed Group were significantly higher than those of Contorl Group(p-value<0.05) and those of test-abnormal persons were higher than those of test-normal persons. SCE frequencies linearly increased with not only current but also cumulative VCM exposure levels(p-value<0.05). These results suggest that adverse health effect may ensue from VCM exposure to as low as 1 ppm. But SCE frequencies had no statistically significant correlation with drinking amounts, smoking amoutns, or radiation dose equivalents. Questionnaire was revised by referring to these results and formula estimating cumulative VCM exposure levels based on occupational history in questionnaire were made. In addition, were presented methods evaluating work environments and multiphasic screening test for PVC workers.

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Original Article
The Response Rate of Follow up Examination and Positive Predictive Value of Screening Items of Workers Aged 30 and Over
Kyung Eun Lee, Jae Yong Park, Byung Yeol Chun
Korean Journal of Occupational and Environmental Medicine 1990;2(1):13-22.   Published online February 28, 1990
DOI: https://doi.org/10.35371/kjoem.1990.2.1.13
AbstractAbstract PDF
No abstract available.

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