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Case Report
A Case of Exercise-induced Rhabdomyolysis with Hepatitis
Seong Ah Kim, Sang Je Jung, Chae Yong Lee, Bong Goo Ha, Ki Soo Park
Korean Journal of Occupational and Environmental Medicine 2006;18(1):67-72.   Published online March 31, 2006
DOI: https://doi.org/10.35371/kjoem.2006.18.1.67
AbstractAbstract PDF
BACKGROUND
Rhabdomyolysis is a relatively rare disease caused by various factors and is characterized by skeletal muscle damage. While crush injury is the most common cause in Korea as well as other countries, overexertion is an important common cause among young men in daily life. Although exercise-induced rhabdomyolysis is already well published among athletes or military persons, there have been few reports in workers.
CASE
REPORT: We observed a 28-year-old male worker who had elevated liver transaminases during a periodic workers' health checkup. Although he did not exhibit the typical pattern of toxic hepatitis, we had to exclude any possibility of dimethylacetamide-induced hepatitis (DIH) because he had worked in a spandex-producing factory, which already had a history of many DIH cases over several years. We performed careful history taking, several laboratory tests, liver ultrasonography and liver biopsy. We also investigated the results of biological monitoring and air concentrations of dimethylacetamide. The findings from these examinations supported the clinical diagnosis of exercise-induced rhabdomyolysis with hepatitis.
CONCLUSION
This case demonstrates that exercise can induce rhabdomyolysis and hepatitis. This disease must be treated by prompt and appropriate management because it might develop more serious complications such as acute renal failure.

Citations

Citations to this article as recorded by  
  • Exercise-induced rhabdomyolysis mechanisms and prevention: A literature review
    Jooyoung Kim, Joohyung Lee, Sojung Kim, Ho Young Ryu, Kwang Suk Cha, Dong Jun Sung
    Journal of Sport and Health Science.2016; 5(3): 324.     CrossRef
  • Literature review of effect of work pattern (day shift and night shift) on worker's health
    Ki-Youn Kim, Man-Su Cho, Won-Mo Gal
    Journal of the Korea Safety Management and Science.2013; 15(2): 1.     CrossRef
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