Annals of Occupational and Environmental Medicine

Original Article

Evaluation of Ototoxicity by Mixed Organic Solvents Using the Upper Limit of Hearing: Ji Ho Lee, Cheol In Yoo, Choong Ryeol Lee, Hun Lee, Young Hee Choi, Nam Jung Kim, Yangho Kim; Korean Journal of Occupational and Environmental Medicine 2004;16(4):391-400. Published online December 31, 2004; DOI: https://doi.org/10.35371/kjoem.2004.16.4.391

Abstract PDF: OBJECTIVES
This study evaluated the ototoxicity by mixed organic solvents on workers'hearing using the upper limit of hearing(ULH).
METHODS
Seven hundred ninety-seven male workers in the ship building industry who were evaluated by interview with an upper limit of hearing from August 2000 to July 2002 were enrolled in the study. The subjects were divided into 3 groups according to exposure profile and job: officers, field supporters, and painters. To assess the ototoxicity of mixed organic solvent exposure on hearing, with regard to confounders, the general liner model was used.
RESULTS
After controlling for the possible confounders, such as age, career, noise exposure level, tinnitus, alcohol intake, and smoking, the estimated mean for ULH of the painter group was higher than that of the officer and the field supporter groups. These differences of mean ULH were at the borderline of statistically significance(p=0.069).
CONCLUSIONS
The results of this study suggest that a relatively lower level of mixed organic solvent chronically affected the hearing organ or auditory pathway. ULH seems to be a useful method for early detection of the ototoxicity of organic solvents.

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Original Article

Phototoxic Dermatitis by Coal Tar Containing Paint: Yun Chul Hong, Eun Hee Ha, Hye Sook Park; Korean Journal of Occupational and Environmental Medicine 1997;9(2):267-274. Published online June 30, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.2.267

Many workers who used coal tar containing paints in shipyard industry have dermatitis, but the etiology is not known well. Our research is to fond out the etiology of the dermatitis and to provide proper management. Methods of this research are comprised of 3 steps. First, we diagnosed dermatitis by questionnaire and dermatologic examination and evaluated air level of coal tar pitch volatiles in workplace. Second, we confirmed coal tar phototoxicity by in vitro cell experiments. Third, we evaluated the effects of intervention. The results were as follows ; Questionnaire survey showed that the lesions of dermatitis were mainly on the sun exposed area and the symptoms were strongly associated with season, weather, and time. Air levels of coal tar pitch volatiles in workplace were higher than NIOSH standard (0.1 mg/m(3), cyclohexane solubles). Inhibitory effects of cellular proliferation by coal tar containing paints and UVA (365nm) exposure showed coal tar phototoxicity. Intervention was done by UV barrier cream(BPF 30) and 72.7% workers who applied UV barrier cream improved after 2 months later. Conclusively, the etiology of dermatitis of shipyard workers who used coal tar containing paint was coal tar phototoxicity, and this dermatitis would be protected by UV barrier cream.

Citations

Citations to this article as recorded by

Overview of occupational cancer in painters in Korea
Jun-Pyo Myong, Younmo Cho, Min Choi, Hyoung-Ryoul Kim
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef

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