Annals of Occupational and Environmental Medicine

Original Article

Styrene in Air and Blood and Mandelic acid in Urine in the Workers exposed to Styrene: Ho Keun Chung, Seong Kyu Kang, Jeong Sun Yang, Ki Woong Kim, Jong Seong Lee, Young Sook Cho, In Jeong Park; Korean Journal of Occupational and Environmental Medicine 1994;6(1):113-121. Published online February 28, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.1.113

The concentration of styrene in air and in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a plyethylene bottle and analyzed by has chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic acid were 8.16 ppm (geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory. Styrene in blood showed large difference by the working process. Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890 g/g creatinine and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption.

Citations

Citations to this article as recorded by

Evaluation of the Suitability of Establishing Biological Exposure Indices of Styrene
Ah-rum Choi, Sung-guk Im, Mi-young Lee, Se-Hoon Lee
Safety and Health at Work.2019; 10(1): 103. CrossRef

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