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Original Article
- Pneumonitis by Methylene Chloride
- Kyu jin Chang, Jong tae Park, Eun kyoung Kim, Byoung gwon Kim, Hae joon Kim
- Korean Journal of Occupational and Environmental Medicine 2005;17(4):365-371. Published online December 31, 2005
- DOI: https://doi.org/10.35371/kjoem.2005.17.4.365
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Abstract
PDF - OBJECTIVES
The authors report a case of pneumonitis caused by methylene chloride (MC).
METHODS
The patient was examined and diagnosed by clinical, radiologic, laboratorial and medical evaluation. The concentration of MC in the factory was measured to determine the exposure level.
RESULTS
The patient had an infiltration in chest X-ray, which underwent rapid relief of radiological finding, respiratory acidosis and hypoxemia in arterial blood gas analysis, and a ground-glass opacity in high resolution computerized tomography. MC was the only exposed chemical compound in this case. The concentration of MC was 39.9 ppm in the factory.
CONCLUSIONS
We diagnosed this to be a case of pneumonitis by MC based on clinical laboratory findings, exposure history to MC and MC concentration in the factory.
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Case Report
- A Case of Toxic Hepatitis in a Worker Exposed to a Cleansing Agent Mainly Composed of Methylene Chloride
- Bong Goo Ha, Jin Seok Kim, Jay Young Yu, Kuck Hyun Woo, Jung Oh Ham, Seong Yong Yoon, Yong Seok Jang, Sang Je Jung
- Korean Journal of Occupational and Environmental Medicine 2004;16(2):210-219. Published online June 30, 2004
- DOI: https://doi.org/10.35371/kjoem.2004.16.2.210
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Abstract
PDF
- OBJECTIVES
To report a case of toxic hepatitis in a worker exposed to a cleansing agent mainly composed of methylene chloride.
METHODS
A 27-year-old female worker who had worked in an inspection and packing position of semiconductor parts in a factory using methylene chloride as a metal cleansing solvent was hospitalized due to fever, chill and generalized aches. We evaluated her with blood tests, abdominal ultrasonographic scan and abdominal CT scan and also took her occupational history.
RESULTS
The patient showed acute hepatitis in blood and radiologic tests after admission. The serologic tests for viral hepatitis A, B, C and autoimmune hepatitis were negative. She had no history of significant alcohol use, recent medication or drug allergy. After admission, her symptoms were improved and liver enzyme levels(AST and ALT) were markedly reduced. She returned to her workplace after discharge. Thereafter, however, her previous symptoms were recurred and she was hospitalized again 2 days after returning to her workplace. After this second admission, she showed acute hepatitis in blood tests and her symptoms were improved and liver enzyme levels were markedly reduced with the same pattern as those of the first admission. On the 11th day of the second admission, liver enzyme levels were normalized and she was discharged from hospital.
CONCLUSIONS
We presume that this patient`s liver injury was related to the methylene chloride presence at her workplace due to her clinical symptoms, blood tests, radiologic tests and occupational history. -
Citations
Citations to this article as recorded by
- Death Due to Acrylic Adhesive (Dichloromethane): A Case Report
Ho Bong Hyun, Jo Youn Park, Hyeong Sin Park, Jeong Hyun Hong, Myung Guon Ko, Hyun Wook Kang, Hyoung Soo Lim
Korean Journal of Legal Medicine.2022; 46(4): 133. CrossRef - A case report of toxic hepatitis caused by chloroform in automotive parts manufacturer coating process
Jong Hyun Hwang, Jung Il Kim
Annals of Occupational and Environmental Medicine.2022;[Epub] CrossRef - Occupational Hepatic Disorders in Korea
Hyoung Ryoul Kim, Tae Woo Kim
Journal of Korean Medical Science.2010; 25(Suppl): S36. CrossRef
- Death Due to Acrylic Adhesive (Dichloromethane): A Case Report
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- 3 Crossref
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