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Research Article
Iron Deficiency is Not Associated with Increased Blood Cadmium in Infants
Jung-Hun Park, Sangkyu Park, Yangho Kim
Ann Occup Environ Med 2014;26:3-3.   Published online February 10, 2014
DOI: https://doi.org/10.1186/2052-4374-26-3
AbstractAbstract PDFPubReaderePub
Objectives

To determine whether blood cadmium concentration is elevated in iron-deficient infants.

Methods

Blood cadmium and serum ferritin concentrations, serum iron/total iron-binding capacity (Fe/TIBC) and complete blood counts were measured in 31 iron deficient and 36 control infants, aged 6–24 months. All 31 iron-deficient infants received iron supplementation for 1–6 months.

Results

Blood cadmium concentrations were measured again in 19 of the iron deficient infants after their ferritin levels returned to the normal range. The mean blood cadmium concentration did not differ significantly in iron deficient and control infants. The mean blood cadmium concentration in the 19 iron-deficient infants was not significantly altered by ferric hydroxide treatment, while their hemoglobin, ferritin, and Fe/TIBC (%) concentrations were significantly higher after than before treatment.

Conclusion

These findings indicate that iron deficiency does not increase blood cadmium concentrations in infants, in contrast with the effects of iron deficiency on manganese and lead concentrations.


Citations

Citations to this article as recorded by  
  • Intra- and Inter-Day Element Variability in Human Breast Milk: Pilot Study
    Kenta Iwai, Miyuki Iwai-Shimada, Kaname Asato, Kunihiko Nakai, Yayoi Kobayashi, Shoji F. Nakayama, Nozomi Tatsuta
    Toxics.2022; 10(3): 109.     CrossRef
  • Blood heavy metal concentrations in pregnant Korean women and their children up to age 5 years: Mothers' and Children's Environmental Health (MOCEH) birth cohort study
    Kyoung Sook Jeong, Eunhee Ha, Ji Young Shin, Hyesook Park, Yun-Chul Hong, Mina Ha, Suejin Kim, Soo-Jeong Lee, Kyung Yeon Lee, Ja Hyeong Kim, Yangho Kim
    Science of The Total Environment.2017; 605-606: 784.     CrossRef
  • The high‐molecular‐weight kininogen Domain 5 is an intrinsically unstructured protein and its interaction with ferritin is metal mediated
    Annissa J. Huhn, Derek Parsonage, David A. Horita, Frank M. Torti, Suzy V. Torti, Thomas Hollis
    Protein Science.2014; 23(8): 1013.     CrossRef
  • Iron deficiency increases blood concentrations of neurotoxic metals in children
    Yangho Kim, Sangkyu Park
    Korean Journal of Pediatrics.2014; 57(8): 345.     CrossRef
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Case Report
Aplastic Anemia in a Petrochemical Plant Worker
Young Mann Baak, Yong Hyu Choi, Seong Kyu Kang, Ji Hong Kim, Kyoung Ah Kim, Young Lim, Joung Wook Lee
Korean Journal of Occupational and Environmental Medicine 1999;11(2):287-292.   Published online June 30, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.2.287
AbstractAbstract PDF
Aplastic anemia is characterized by pancytopenia with hypocellular bone marrow. Fifty percent of the cases are idiopathic and the rest are caused by various agents including drugs, chemicals, radiation and viruses. It is difficult to link specific etiologic agents, especially chemicals to the development of aplastic anemia because multiple or unknown exposures may be involved in. Benzene, a common industrial chemical and a component of gasoline, may lead progressively to pancytopenia, aplastic anemia and leukemia when exposed. A petrochemical worker with aplastic anemia was referred to our hospital to evaluate a relationship between the job history and the disease. He worked in the petrochemical plant for .21 years and was exposed to low-level benzene. There was not any other etiologic agent except benzene and this is the case report of aplastic anemia which possibly due to benzene exposure.

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Original Article
Type of Anemia Due to Organic Solvents
Choong Ryeol Lee, Cheol In Ryu
Korean Journal of Occupational and Environmental Medicine 1998;10(2):180-188.   Published online May 31, 1998
DOI: https://doi.org/10.35371/kjoem.1998.10.2.180
AbstractAbstract PDF
The purpose of this study Is whether we can presuppose the correlation between some type of anemia and exposure to organic solvents using some hematologic index such as MCV, RDW and MCHC. The authors conducted the hematological examination of 160 male workers who were exposed organic solvents and those of 167 control workers. The type of anemia was slightly macrocytic anemia, and the RDW was generally homogenous in workers exposed to organic solvents whereas those of control were normocytic and homogenous.

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