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Volume 11 (4); December 1999
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Case Reports
Three Cases of Work-Related Suprascapular Entrapment Neuropathy
Du Shin Jeong, Ki Bum Sung, Hyun Kil Shin, Moo Young Ahn, Hyeong Su Kim, Young Eui Hong
Korean Journal of Occupational and Environmental Medicine 1999;11(4):585-593.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.585
AbstractAbstract PDF
OBJECTIVES
Entrapment of the suprascapular nerve is frequently overlooked in the differential diagnosis of shoulder pain.
METHODS
Suprascapular entrapment neuropathy is a well-defined clinical entity and EMG and NCV is used to confirm a diagnosis. But the diagnosis is typically not considered until patients develop severe weakness secondary to atrophy of the spinous musculature that the nerve supplies.
RESULTS
A narrow suprascapular notch has rarely been reported as a work-related factor of this entrapment neuropathy. Diagnosis of suprascapular entrapment neuropathy is based on the patients' clinical course, neurologic, radiologic, and electrophysiologic findings. One of the most helpful evaluations was the anteriorposterior projection with the X-ray tube angled 15-30 degree caudally. The suprascapular entrapment neuropathy is relatively uncommon entity of shoulder discomfort (pain, weakness, and atrophy).
CONCLUSIONS
If the worker who used his shoulder joint repetitiously having the shoulder pain and muscle weakness, we must rule out the suprascapular entrapment neuropathy. And it is needed to evaluate the motions which cause suprascapular entrapment neuropathy as the ergonomic factor.

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Assessment of Voice Disorder following Inhalation Injury
Eun Seo Kim, Yoon Jeong Doh, Jouguk Won, Jaehoon Noh
Korean Journal of Occupational and Environmental Medicine 1999;11(4):579-584.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.579
AbstractAbstract PDF
Objective: Injury to the airway, found in 25% to 35% of patients admitted to major burn center, is now the leading cause of death in burn patients. Significant inhalation injury can increase the patient mortality rates by up to 20%. Toxic compounds in smoke can include phosgene, ammonia, sulfur dioxide, and chlorine from plastics and various oxides and aldehydes from burning wood. These compound directly injure airway epithe hal cells, causing an intense inflammatory response with significant edema. After the critical problem is controlled with intensive care in inhalation burn patients, less critical but significant laryngeal function such as protection, phonation and deglutition may often be overlooked.
METHOD
& RESULT: We have experienced a male patient who was injured by inhalation of toxic compound in ship under cohstruction. He have suffered from pulmonary problem, bronchiohitis obhiterans. Voice disorder was assessed and managed by otolaryngologists after resolving the pulmonary lesion.
CONCLUSION
Evaluation and treatment of patients suspected of inhalation injury should include anatomical and functional aspects of the larynx as well as critical problem of the airway.

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Original Articles
The Influence of Smoking, Alcohol Ingestion, and Physical Activity on Copper, Zinc and Ceruloplasmin in Blood of Male Adults
Jin Wan Park, Eun Yong Kang, In Cheol Shin, Byung Sun Choi, Jung Duck Park, Im Won Chang, Yeon Pyo Hong
Korean Journal of Occupational and Environmental Medicine 1999;11(4):569-578.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.569
AbstractAbstract PDF
Objective : To investigate the influence of smoking, alcohol ingestion, and physical activity on copper and zinc in RBC and serum and serum ceruloplasmin, this study was performed in a cross-sectional study in 113 healthy men aged 20 to 40 years who had no symptomatic liver, heart, gastrointestinal, and other chronic diseases.
METHODS
At the men's entry into the study, blood samples were drawn from each subject and immediately centrifuged for analysis of copper, zinc, iron, ceruloplasmin, total cholesterol, and hematocrit. Each man completed a questionnaire that provided information on smoking, amount of alcohol intake, and physical activity. Partial regres sion analysis was performed on confounding variables such as age, body mass index, hematocrit, serum cholesterol, and serum iron.
RESULTS
In general linear models, adjustment for confounding variables did not show statistical differences, and there was only an increasing tendency in serum copper in heavy smoker (P=0.0678). There was no difference between high physical activity with mild smokers and lower physical activfty with, heavy smokers.
CONCLUSIONS
This study suggested that copper, zinc and eeruloplasmin were not good biomarker for early effect by smoking, alcohol intake and physical activity in young adult. However, selection bias should be considered in evaluation of this result, and a large prospective study will be needed in advance on usefulness of copper, zinc and ceruloplasmin as a marker for risk factors and early change of atherosclerosis.

Citations

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  • Assessment of reference ranges for blood Cu, Mn, Se and Zn in a selected Italian population
    Beatrice Bocca, Roberto Madeddu, Yolande Asara, Paola Tolu, Juan A. Marchal, Giovanni Forte
    Journal of Trace Elements in Medicine and Biology.2011; 25(1): 19.     CrossRef
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Induction of Apoptosis by Heavy Metals in HL-60 Cells
Nam Song Kim, Tae Ho Seong, Kwang Ho Cho, Jung Ho Youm, Dai Ha Koh
Korean Journal of Occupational and Environmental Medicine 1999;11(4):557-568.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.557
AbstractAbstract PDF
OBJECTIVES
Apotosis induced by metals and metal-related deleterious conditions has only recently been studied. Although the toxic effects of heavy metal are well described, little is known about the mechanism of apoptosis by heavy metal toxicity. This study is designed to define the induction of apoptosis by which heavy metals exert the cytotoxic effect on human promyelocytic leukemic HL-60 cells.
Methods
After the incubation with CdC12, Na2SeO3 and HgC12, viability of the cells were measured by MTT assay. DNA fragmentation was analyzed by electrophoresis. For measurement of caspase 1 and 3-like proteases activity, the whole lysates were subjected to the proteolytic cleavage and then measured by using fluorospectrometry. c-JUN N-terminal kinase (JNK) activity was detected by an in vitro kinase assay. Transcriptional activities of activating protein-1 (AP-1) and nuclear factor-kB (NF-kB) were measured by elec trophoresis mobility shift assay (EMSA).
RESULTS
Cadmium (l2OuiN/I) and selenium (30,iM) induce the apoptosis of HL-60 cells which is characterized by the ladder pattern of DNA fragmentation. Cadmium and selenium induce the activation of caspase-3 in a time dependent manner. They also increase the phosphotransferase activities of c-JUN N-terminal kinase (JNK) in cadmium and selenium treated HL-60 cells. Furthermore, cadmium and selenium increase the activation of transcriptional factors including AP-i and NF-kB.
CONCLUSIONS
These results suggest that cadmium and selenium induce the apoptotic death of HL-60 cells via activation of DEVD-specific caspase, JNK and transcriptional factors such as AP-1 and NF-kB.

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Effects of occupation, life style and genetic polymorphism of CYP1A1, GSTM1, and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentration
Heon Kim, Hyun Sul Lim, Jong Won Kang, Holik Lee, Yong Dae Kim, Hong Mei Nan, Chul Ho Lee
Korean Journal of Occupational and Environmental Medicine 1999;11(4):546-556.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.546
AbstractAbstract PDF
OBJECTIVES
This study was performed to describe the distribution patterns of urinary 1-hydroxypyrene (1-OHP) and 2naphthol concentration in coke oven workers and workers not occupationally exposed to polycyclic aromatic hydrocarbons (PAH), and to determine the effects of occupation life style, and genetic polymorphism of cytochrome P450 1A1 (CYP1A1), glutathione Stransferase mu 1 (GSTM1) and theta 1 (GSTT1) on urinary 1- OHP and 2-naphthol concentration.
METHODS
The study subjects were 19 coke oven workers and 156 shipyard workers. A questionnaire was used to obtain data about detailed smoking and food intake history. Urinary 1OHP and 2naphthol concentration and genetic polymorphism of CYPIA1, GSTM1, and GSTT1 were analyzed.
RESULTS
The urinary 1-OHP and 2-naphthol concentration was higher in the coke oven workers and in smokers. Urinary 1-OHP concentration was significantly correlated with time after last intake of roasted meat in non-smoking coke oven workers, whereas urinary 2-naphthol concentration was with amount of cigarette smoking at the sampling day in smoking shipyard workers. Urinary 1-OHP, but not 2-naphthol, concentration of the shipyard workers with Ile/Ile type of CYP1A1 vas significantly lower than that of the shipyard workers with other CYP1A1 genotype.
CONCLUSIONS
Urinary 1-OHP would be a better marker for occupational exposure to PAH in coke oven workers, and urinary 2naphthol might be better for non-occupational inhalation exposure to PAH. CYP1A1 would not play an important role in the metabolism of naphthalene but in the metabolism of pyrene.

Citations

Citations to this article as recorded by  
  • 1-Hydroxypyrene and oxidative stress marker levels among painting workers and office workers at shipyard
    Younglim Kho, Eun-Hee Lee, Hong Jae Chae, Kyungho Choi, Domyung Paek, Sangshin Park
    International Archives of Occupational and Environmental Health.2015; 88(3): 297.     CrossRef
  • A study of the status of exposure to polycyclic aromatic hydrocarbons (PAHs) in relation to its metabolites among workers in a Korean chemical factory
    Kwan Lee, Hyun-Sul Lim, Heon Kim
    Ciência & Saúde Coletiva.2014; 19(12): 4809.     CrossRef
  • 1-Hydroxypyrene as a biomarker of PAH exposure among subjects living in two separate regions from a steel mill
    Mi-Sun Lee, Ki-Do Eum, Kyung-Duk Zoh, Tak-Soo Kim, Yun-Suk Pak, Domyung Paek
    International Archives of Occupational and Environmental Health.2007; 80(8): 671.     CrossRef
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Health Effects of Aircraft Noise on Residents Living Near an Airport
Kyung Jong Lee, Jae Beom Park, Jae Yeon Jang, Sun Mi Cho, Se Wi Lee, Jong Goo Kim, Soon Young Lee, Jong Ja Kwak, Ho Keun Chung
Korean Journal of Occupational and Environmental Medicine 1999;11(4):534-545.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.534
AbstractAbstract PDF
Objectives
; This study was conducted to reveal the health effects of aircraft noise on the residents live near the military airport.
METHODS
We sampled systematically 87 residents as the high exposed group, 58 residents as the low exposed group according to the geographical distance from the airport. We also sampled 67 residents as the control group lived far from the airport. Noise levels were measured for conform the exposures. Self-administered questionnaires for symptoms, air conduction hearing threshold level, blood pressure blood cholesterol with health examinations, and SCL-90-R were introduced to get the data from the residents.
RESULTS
The Ld/n at the area near the airport was 72.4 dB, however that of control area was 67. 7 dB. The value of pure tone average, high pure tone average, and threshold of 4,000 Hz were decreased with exposure level significantly. Linear regression analysis showed that the noise exposure level of the airport was related to the hearing threshold at pure tone average, threshold of 4,000 Hz, and high pure tone average. The systemic and diastolic blood pressure showed dose-response relationship with noise exposure. The prevalence of hypertension was higher in exposed group, but not statistically significant. In linear regression, noise level was related to systolic and diastolic blood pressure with other variables such as age, sex, BMI (Body Mass Index), and family history of hypertension. SCL-90-R showed that exposed group had higher score significantly in neurotic and psychologic variable and felt the various somatic symptoms.
CONCLUSIONS
These results suggest that aircraft noise would influence hearing loss at low frequencies as well as 4,000 Hz and higher frequencies, systolic and diastolic blood pressure, and psychological response.

Citations

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  • Influence of noise exposure on cardiocerebrovascular disease in Korea
    Myoungjin Oh, Kwangsoo Shin, Kyungah Kim, Jungwoo Shin
    Science of The Total Environment.2019; 651: 1867.     CrossRef
  • Study on the Health Status of the Residents near Military Airbases in Pyeongtaek City
    Hyunjoo Kim, Sangchul Roh, Ho-Jang Kwon, Ki Chung Paik, Moo-Yong Rhee, Jae-Yun Jeong, Myung Ho Lim, Mi-Jin Koo, Chang-Hoon Kim, Hae Young Kim, Jeong-Hun Lim, Dong-Hyun Kim
    Journal of Preventive Medicine and Public Health.2008; 41(5): 307.     CrossRef
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Reactive Oxygen Species Generation of Refractory Ceramic Fiber and Rock Wool-Induced Alveolar Macrophage and Associated Signal Transduction Pathway
Eun Kyung Kim, Kyoung Ah Kim, Young Lim, Kyung Sook Yang, Hyun Sook Oh, Kweon Haeng Lee
Korean Journal of Occupational and Environmental Medicine 1999;11(4):527-533.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.527
AbstractAbstract PDF
OBJECTIVES
It is known that the high fibrogenecity of particles is connected with their cytotoxicity for macrophages. Although the molecular mechanism leading to fiber-induced fiber-induced cytotoxicity is still not clear, several mechanism have been suggested. The release of reactive oxygen species (ROS) from activated alveolar macrophages (AM) by dust have been suggested as a possible mechanism of particle-induced cell damage. But the mechanism which man-made vitreous fiber (MMVF) induces the production of ROS in AM is still not clear. In this study, we evaluated the relationship between ROS production and lactate dehydrogenase (LDH) release from alveolar treated with refractory ceramic fiber (RF2) or rock wool (RW1) and signal transduction path-way of ROS production in RF2 or RW1 exposed AM.
METHODS
We investigated LDH release from MMVF-stimulated AM for index of cytotoxicity. To determine what kind of signal transduction pathways are involved in MMVF-stimulated ROS generation, we used some drugs which have an effect on the signal transduction pathway.
RESULTS
RF2 and RW1 induced increase of LDH release with dose-dependent manner with RF2 having greater effect than RW1. There was a dose-dependent increase in the production of ROS by RF2 or RW1. At all level of concentration,. RF2 induced more ROS production than RW1. Inhibitors of PKC (bisindolylmaleimide), PLC (U73122 and neomycine) and PTK (genistein and erbstatin) suppressed RF2 or RW1-induced ROS production.
CONCLUSION
There was significant correlation between LDH release and ROS production from AM treated with RF2 or RW1. RF2 and RW1 induced ROS generation through protein kinase C (PKC), phospholipase C (PLC) and protein tyrosin kinase (PTK) pathways.

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Urinary hippuric acid excretion by intake of food and drink
Jung Il Kim, Tae Hyuk Park, Kap Yeol Jung, Hai Rim Shin, Joon Youn Kim
Korean Journal of Occupational and Environmental Medicine 1999;11(4):516-526.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.516
AbstractAbstract PDF
OBJECTIVES
Urinary hippuric acid levels have been usually determined to ' evaluate workers exposed to toluene. Food and drink intake could affect urinary hippuric acid excretion and this study was carried out to investigate what kinds of food and drink would affect urinary hippuric acid excretion.
METHODS
The subjects were 136 medical school students. Authors measured urinary hippuric acid levels three times from 10 a. m. to noon; before, one hour after and two hours after food or drink-intake, and they were asked not to eat from the previous night (9 p. m) of testing. We selected six diets (bread and coffee, brown sauce noodle, Korean style meal, noodle, pork'galbi and rice and soybean stew and rice), six fruits (apple, grape, orange, pear, persimmon and plum) and five beverages (Alps-D(R), Demisoda(R), Orange juice(R), Pear juice(R) and Pocari sweat(R)). Analysis of urinary hippuric acid was performed by high performance liquid chromatography.
RESULTS
Intake of popular Korean diets, fruits and some drinks didn' t affect urinary hippuric acid excretion. But intake of sodium benzoate-contained Alps-D(R) increased urinary hippuric acid excretion.
CONCLUSIONS
For the health examination on workers exposed to toluene, the history of diet and fruit intake can be negligible, but that of beverage intake should be included.

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Determinants on Occurrence of Hypertension in the Korean Adult Male Workers in an Industry: a Nested Case-control Study
Noh Won Park, Il Suh, Tae Yong Lee, Sun Ha Jee, Se Ho Kim
Korean Journal of Occupational and Environmental Medicine 1999;11(4):505-515.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.505
AbstractAbstract PDF
OBJECTIVES
In order to find determinants on occurrence of hypertension in the adult male workers in an industry, a nested case-control study was performed in Seoul, Korea at the periodic health examination center.
METHODS
A cohort was formed with 1,690 normotensive male workers in 1996 and 1997, who had participated in three consecutive periodic health examinations from 1996 through 1998. Cases were 89 hypertensives in 1998, controls were 356 selected by 1:4 age-matching among 1,601 normotensives in 1998. Baseline health behavior (drinking smoking, exercise), baseline health examination data (height, weight, BMI, blood pressure. hemoglobin, fasting blood sugar, serum total cholesterol), and the changes of data during the study period were compared between case and controls. And multiple logistic regression was performed to find determinants on occurrence of hypertension.
RESULTS
There was significant difference in alcohol consumption amount, baseline weight, DM1, blood pressure, total cholesterol, and hemoglobin level. The main determinants on occurrence of hypertension from multiple logistic regression analysis were baseline systolic blood pressure (OR, 1. 13; 95% confidence interval 1.08-1.18%), 15-21 drinks per week (OR, 4.17; 95 % confidence interval 1.44-12.11), and 22 or more drinks per week (OR, 5.29; 95 % confidence interval 1.50-18.58).
CONCLUSIONS
This study showed the importance of baseline blood pressure level and adequate drinking habit for the management of hypertension.

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Need Assessment for Stage of Behavior Change in Workplace Health Promotion Strategy
Kang Sook Lee, Jung Wan Koo, Hyeon Woo Yim, Hyun Sook Hong, Joung Min Lee, Won Chul Lee, Chung Yill Park, O'Donnell, M , Kwang Ho Meung
Korean Journal of Occupational and Environmental Medicine 1999;11(4):492-504.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.492
AbstractAbstract PDF
OBJECTIVES
In order to evaluate the stage of behavior change for health promotion strategy in workplace METHODS: Questionnaire survey was carried out for 309 workers who employed in H Electronics company in Kyongin area from September to October 1998.
RESULTS
According to need assessment of four step such as precontemplation stage, contemplation stage, action stage, maintenance stage which were to change of behavior for health promotion, the percent for quitting smoking were observed 48.8%, 43.1%, 8.1%. 0 %, and for the restriction of drinking were 29.8%, 10.6%, 9.3%, 5.3%; for fitness 11.1%, 31.0%, 37.3%, 20.6% in male 26.6%, 27.8%, 26.6%, 19.0% in female, for regular diet 26.1%, 19.8%, 38.7%, 15.3% in male, 27.8%, 22.2%, 40.0%, 10.0 % in female and for stress management 5.8%, 10.6%, 8.7%, 75.0% in male, 13.6%. 22.7%, 19.7%, 44.0% in female. In heavy smoker (p=0.017) and heavy drinker, (p=0.021) the percent of precontemplation stage was significantly higher than in lower drinker and light smoker.
CONCLUSIONS
This study suggested that company support for health promotion in workplace was weak and workers of high risk group for smoking and drinking were in precontemplation stage. So before conducting the health promotion program, health risk appraisal and need assessment for stage of behavior change should be taken for the efficient heath promotion strategy.

Citations

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  • Effects of a Tailored Health Promotion Program to Reduce Cardiovascular Disease Risk Factors Among Middle-Aged and Advanced-Age Bus Drivers
    Gyu-Seok Hwang, Jae-Wook Choi, Seoung-Hyung Choi, Seoung-Gil Lee, Kyung-Hee Kim, Yong-Min Cho, Chungsik Yoon
    Asia Pacific Journal of Public Health.2012; 24(1): 117.     CrossRef
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Manganese Exposure and its Health Hazards of Welders
Deog Hwan Moon, Byung Chul Son, Dong Mug Kang
Korean Journal of Occupational and Environmental Medicine 1999;11(4):476-491.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.476
AbstractAbstract PDF
OBJECTIVES
In order to evaluate the degree of manganese exposure and its health hazards effect on welders in manufacturing industry.
METHODS
The author measured airborne, blood and urine concentrations of manganese and blood chemistry, and also observed clinical symptoms and signs on 60 welders for case an.d 60 non-welders for control working in manufacturing industry by age maching method.
RESULTS
The geometric means of blood and urine concentrations of manganese were 1.13 +/- 1.38 microgram /dI and 2.52 +/- 1.37 microgram /I for Welders group, 1.09 +/- 1.68 microgram /dl and 1.86 +/- 1.34 microgram / I for Non-welders group. Airborne concentration of manganese was 0. 15 +/- 1.66 mg/m3 for exposured group, and the urinary mean concentration of manganese was statistically significant difference between exposured and non-welders group (P < 0.05). Clinical signs in welders group were palmomentle reflex (23.3%), tremor (20.0%) and grabellar sign (5.0%). Symptoms in welders group were fatigue (66.7%), amnesia (66.7%), excessive sweating (51.7%), nervousness (51.7%), general weakness (48. 3%) and arthralgia (46.7%) and so on, and there was statistically significant difference compared to non-welders group (P<0.05). Manganese exposure effects on blood chemistry were not observed. There were statistically significant correlation between manganese concent- ration in blood and urine (r=0. 269), airborne and urine (r=0. 601) and airborne and blood (r=0. 268).
CONCLUSION
The author suggest that further studies are followed to evaluate the health status of welders whose blood and urine manganese concentrations were below normal reference level, and to establish the questionnaire and the diagnostic tools for early detecting the chronic manganese poisioning on welders.

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  • Derivation of an occupational exposure level for manganese in welding fumes
    Lisa A. Bailey, Laura E. Kerper, Julie E. Goodman
    NeuroToxicology.2018; 64: 166.     CrossRef
  • Associations between Airborne Manganese and Blood Manganese in the Korean General Population according to KNHANES 2008-2009
    Kyung Sick Jung, Jong Dae Lee, Yong Bae Kim
    Journal of Environmental Science International.2013; 22(12): 1589.     CrossRef
  • Neurobehavioral Deficits and Parkinsonism in Occupations with Manganese Exposure: A Review of Methodological Issues in the Epidemiological Literature
    Robert M. Park
    Safety and Health at Work.2013; 4(3): 123.     CrossRef
  • Olfactory functions at the intersection between environmental exposure to manganese and Parkinsonism
    Silvia Zoni, Giulia Bonetti, Roberto Lucchini
    Journal of Trace Elements in Medicine and Biology.2012; 26(2-3): 179.     CrossRef
  • Exposure-Response Relationship and Risk Assessment for Cognitive Deficits in Early Welding-Induced Manganism
    Robert M. Park, Rosemarie M. Bowler, Harry A. Roels
    Journal of Occupational & Environmental Medicine.2009; 51(10): 1125.     CrossRef
  • Sequelae of fume exposure in confined space welding: A neurological and neuropsychological case series
    Rosemarie M. Bowler, Sanae Nakagawa, Marija Drezgic, Harry A. Roels, Robert M. Park, Emily Diamond, Donna Mergler, Maryse Bouchard, Russell P. Bowler, William Koller
    NeuroToxicology.2007; 28(2): 298.     CrossRef
  • State-of-the-Science Review: Does Manganese Exposure During Welding Pose a Neurological Risk?
    Annette B. Santamaria, Colleen A. Cushing, James M. Antonini, Brent L. Finley, Fionna S. Mowat
    Journal of Toxicology and Environmental Health, Part B.2007; 10(6): 417.     CrossRef
  • Issues in neurological risk assessment for occupational exposures: The Bay Bridge welders
    Robert M. Park, Rosemarie M. Bowler, Donald E. Eggerth, Emily Diamond, Katie J. Spencer, Donald Smith, Roberto Gwiazda
    NeuroToxicology.2006; 27(3): 373.     CrossRef
  • Potential occupational risks for neurodegenerative diseases
    Robert M. Park, Paul A. Schulte, Joseph D. Bowman, James T. Walker, Stephen C. Bondy, Michael G. Yost, Jennifer A. Touchstone, Mustafa Dosemeci
    American Journal of Industrial Medicine.2005; 48(1): 63.     CrossRef
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The effectiveness of the intervention in the workplace on patients suffering from Cervicobrachial disorder
Myung Ho Sohn, Jin Su Choi, Seok Joon Sohn, Yang Ok Kim, Jong Park
Korean Journal of Occupational and Environmental Medicine 1999;11(4):460-475.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.460
AbstractAbstract PDF
OBJECTIVES
In order to reveal the effectiveness of the intervention in the workplace on patients suffering from cervicobrachial disorder (CBD), we reexamined 96 workers out of 137 workers suffering from CBD on the assembly lines of an electric manufacturing factory by using questionnaires, physical exams and neurological exams.
METHODS
Analyses were made of the characteristics of the 96 workers of this company suffering from 1994 to 1996 with special concern for differences before and after the improvement of the working environment. After reexamination of the 96 patients the following results were obtained.
RESULTS
We observed an improvement in the 10 most common subjective symptoms of CBD. These symptoms included general fatigue, pain on neck and shoulders, dullness of the upper extremities, back pain and discomfort and a tingling sensation in the hands and wrists (p < 0. 05). The percentage of workers who complained muscle tenderness of neck and shoulder were reduced (p < 0.05). the percentage of workers with abnormal Morley examination was reduced from 28. 5% to 2. 100 (p < 0.01), and of workers with abnormal EMG finding went from 12. 4% to 2. lao (p < 0. 01) and of grade 3 and grade 4 CBD was reduced from 42. 3% and 18. 3% respectively to 33. 3% and 2. ba (p < 0. 01). Grade 3 and over laborers of CBD had higher scores in somatization, anxiety, depression, hostility, interpersonal sensitivity, phobic anxiety, obsessive-compulsive, neurasthenic, hypochondriacal than other sufferers in the SCL-90-R exam (p < 0. 01).
CONCLUSIONS
in conclusion intervention had effectiveness on subjective symptoms of neck and shoulder and decreasing abnormal finding of muscle tenderness, neurological examination and EMG.

Citations

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  • Clinical Study of the Effects of Juglandis Semen Pharmacopuncture Therapy on Shoulder Pain
    Han-Na Choi, Seoung-Whon Lee, Cheol-Hong Kim, Hyun-Min Yoon, Kyung-Jeon Jang
    Journal of Pharmacopuncture.2011; 14(4): 39.     CrossRef
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Usefulness of Power Spectral Analysis for Measurement of Local Muscle Fatigue during Keyboard Task
Soon Young Kwon, Chung Yill Park, Jung Wan Koo, Hyeon Woo Yim, Kang Sook Lee
Korean Journal of Occupational and Environmental Medicine 1999;11(4):449-459.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.449
AbstractAbstract PDF
OBJECTIVES
Work-related upper extremity disorders of the tendons, nerves, and musdes associated with. repetitive motion represent an increasing proportion of occupational illnesses, medical services, and workers' compensation costs. Severe local muscle fatigue may be a precursor of repetition strain injuries. The demand for objective and quantitative assessment of local muscle fatigue is now increasing. The purpose of this study is to determine the usefulness of power spectral analysis of individual muscle as one of the objective spectral parameters in quantification of local muscle fatigue.
METHODS
From 10 normal male without neuromuscular dysfuction, motor unit action potentials (MUAPs) of three muscles (upper trapezius, infraspinatus, and anterior deltoid) of left shoulder girdle were obtained. The surface electrodes were used and the changes of power spectrum according to frequency components were calculated per minute during the keyboard task for 30-minute period by power spectral analysis of MUAPs signal.
RESULTS
There was a linear relationship between median frequency (MF) and time flow in the upper trapezius muscle, however the same was not observed in other muscles. The MF slope of the upper trapezius muscle showed a decline of the MF over time and reflected the fatigue rate. Other spectral parameters, such as mean frequency and total power were not significantly correlated to time flow during the keyboard task in all three muscles. And no significant correlation was observed between keying rate and slope of median frequency of upper trapezius muscle.
CONCLUSIONS
Above results suggested that the power spectral analysis on median frequency in upper trapezius muscle would be useful in quantification of local muscle fatigue during the keyboard task and local muscle fatigue of shoulder was affected by static posture, not by keying rate.

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Symptom Prevalence and Related Factors of Upper Limb Musculoskeletal Symptoms in Automobile Related Job Workers
Chul Soo Yoon, Se Hoon Lee
Korean Journal of Occupational and Environmental Medicine 1999;11(4):439-448.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.439
AbstractAbstract PDF
OBJECTIVES
The purpose of this study was to determine the prevalence and related factors of upper limb musculoskeltal symptoms among workers in automobile related jobs.
METHODS
Two-hundred and twenty-one workers were volunteered in this 'study consisting of 112 seat installers and 109 auto mechanics. A questionnaire was administered to the workers consisting of questions on demographics, work type and duration, sleep hours, health habits, and standardized descriptions of NJOSH on musculoskeletal symptoms.
RESULTS
Complaint rates of neck and upper extremity musculoskeletal symptoms by anatomical site were as follows: shoulder, 52.0%; neck, 47.1%; wrist and hand, 39.4 elbow, 26.2% and; arm, 24.4%. Significantly higher prevalence of shoulder musculoskele tal symptom was found in middle school than high school graduate, married than unmar ned, less than 6 hours sleep than over 6 hours sleep and, seat installer than auto mechanic group. A significantly higher prevalence of arm, elbow, hand and wrist mus loskeletal symptoms was disclosed in the less than 6 hours sleep than over 6 hours sleep group and the seat installer than the auto mechanic group. Multiple logistic regression analysis identified education, sleep hours and, job type as the main affecting factors for shoulder musculoskeletal symptoms. Sleep hours and job type were the main affecting factors for wrist and hand musculoskeletal symptoms. Sleep hours were the main affecting factors for arm and elbow musculoskeletal symptoms.
CONCLUSIONS
The prevalence of neck and upper limb musculoskeletal symptoms was high in workers who did routine tasks at confined places like seat install-line work. It is recommended that workers performing simple and routine tasks be provided adequate sleep time since lack of sleep was the main affecting factor for most upper limb mus loskeletal symptoms in automobile factory related jobs workers.

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The variation of thiodiglycolic acid concentration in urine with vinyl chloride exposure levels in rats
Seung Jun Wang, Bong Suk Cha, Jae Hoon Roh, Dong Chun Shin, Myung Su Kim, Keun Jae Jeon
Korean Journal of Occupational and Environmental Medicine 1999;11(4):431-438.   Published online December 31, 1999
DOI: https://doi.org/10.35371/kjoem.1999.11.4.431
AbstractAbstract PDF
OBJECTIVES
It is the objective of this research to identify the variation of thiodiglycolic acid (TdGA) in urine with vinyl chloride monomer (VCM) exposure levels through methylation.
METHODS
After rats were exposed to vinyl chloride monomer of 4 levels, 0 mg/m3, 50 mg /m3, 150 mg/m3, 500 mg/m3, respectively, of which urine was sampled in each sampling time of 0 hour, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours, 36 hours, 48 hours. After urine had been methylated with diazomethane in the preliminary experiment and the peak of 146 m/z had been verified, the main experiment was done.
RESULTS
In the variation of TdGA with sampling times, concentration of TdGA increased rapidly in 4 hours and then decreased after 8 hours. When the variation of urinary .TdGA concentration in urine according to exposure level of VCM was verified through Kruskal-Wallis statistical method at each sampling time, the significant increment with the exposure levels at 2 hours, 4 hours, 8 hours after exposure was clarified.
CONCLUSION
TdGA concentration in urine with increment of VCM exposure level increased, especially significantly at 2 hours, 4 hours, 8 hours of sampling time.

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