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Nonspecific Building Related Illnesses
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Chunhui Suh, Eun Hee Ha, Yun Chul Hong, Yoo Mi Chae, Kyu Jin Chang, Jungwon Kim
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Korean Journal of Occupational and Environmental Medicine 2012;24(4):319-327. Published online December 31, 2012
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DOI: https://doi.org/10.35371/kjoem.2012.24.4.319
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 Abstract
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- Nonspecific building related illnesses (NBRI) are an array of diverse symptoms related to working in particular buildings. There are numerous contributing factors, including basic factors (temperature, humidity and ventilation) as well as chemicals, dust, microorganisms, and psychosocial factors.
At the individual level, taking a careful history is the essential first step. After ruling out other diseases, clinicians can start the symptomatic treatment for NBRI. If a relationship to the building is suspected, a walk through evaluation is very helpful. At the group level, standardized questionnaires and investigations of the building environment can be applied simultaneously. If the prevalence of symptoms are greater than that of general population, appropriate interventions have to be provided for prevention and group health care. In both approaches, it is essential to periodically follow up with symptomatic patients and work environments after an intervention. For the management of NBRI, taking care of the patient's symptoms and maintaining a good indoor environment are important. To achieve this goal, cooperation among workers, building managers, employers and occupational health staff is crucial.
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Relationship Between Urinary t, t-muconic Acid and Insulin Resistance in the Elderly
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Hyun Seung Park, Jeong Cheol Seo, Jin Hee Kim, Sang Hyuk Bae, Youn Hee Lim, Soo Hun Cho, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2011;23(4):387-396. Published online December 31, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.4.387
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Abstract
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- OBJECTIVES
To examine the associations between the urinary t, t-muconic acid (t, t-MA) concentration and three indices of insulin resistance; namely, the homeostasis assessment of insulin resistance (HOMA-IR) index, blood insulin level and fasting glucose level.
METHODS
A panel study was performed on the elderly at a public health care center population in the northern area of Seoul between 2008 and 2010. The participants were 560 elderly, over 60 years of age whose urinary t, t-MA and insulin resistance indices had been measured; questionnaires were completed by these participants. A generalized linear mixed (GLM) analysis was adjusted for age, sex, drinking, urinary cotinine, exercise, vitamin intake and body mass index, at a significance level of p<0.05.
RESULTS
A total of 411 participants were finally analyzed after excluding those with diabetes and only one visit to the public health care center. Higher urinary t, t-MA concentrations were linearly associated with the HOMA-IR index, blood insulin level and fasting glucose level in the simple and fully adjusted GLM models. Although there were few limitations, a portion of insulin resistance was proven to be explained by exposure to benzene using r-squared. A significant relationship was also observed between urinary t, t-MA and malondialdehyde (MDA) using the same GLM models.
CONCLUSIONS
Urinary t, t-MA is related to the development of insulin resistance which is a key factor for development of diabetes and its complications induced by oxidative stress.
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Citations
Citations to this article as recorded by  - Exploration of an Area with High Concentrations of Particulate Matter and Biomonitoring Survey of Volatile Organic Compounds among the Residents
Hyunji Ju, Seungho Lee, Jae-Hee Min, Yong-Sik Hwang, Young-Seoub Hong
Journal of Environmental Health Sciences.2023; 49(6): 344. CrossRef - Association between urinary trans,trans-muconic acid and diabetes: a cross-sectional analysis of data from Korean National Environmental Health Survey (KoNEHS) cycle 3 (2015–2017)
Eun Hye Yang, Do Jin Nam, Hyo Choon Lee, Soon Su Shin, Jae-Hong Ryoo
Annals of Occupational and Environmental Medicine.2021;[Epub] CrossRef
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The Relationship Between Amalgam Tooth Fillings and Concentration of Blood Mercury in Elementary School Students in Korea
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Kyu Hwa Lee, Man Joong Jeon, Yun Chul Hong, Jong Han Leem, Mi Na Ha, Ho Jang Kwon, Joon Sakong
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Korean Journal of Occupational and Environmental Medicine 2011;23(4):420-427. Published online December 31, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.4.420
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Abstract
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- OBJECTIVES
The adverse health effects of mercury in dental amalgam have not yet been clarified. This study was conducted to examine the effects of dental amalgam on the concentration of blood mercury in Korean children.
METHODS
A total of 1,275 students were enrolled in the elementary school in Seoul, Incheon, and Daegu. The number and location of dental amalgam filling of teeth were ascertained by oral examination. Dietary habits-including frequency of seafood intake-and other demographic factors were obtained from the children's parents. The concentration of blood mercury was measured by an atomic absorption spectrophotometer to which a hydride generator was installed.
RESULTS
The geometric mean of blood mercury concentration was 1.91 microg/L. It was found that elementary school students in Seoul and the 4th grade elementary school students have the lowest concentration of blood mercury among the study groups. Both linear and secondary linear increase of the concentration of blood mercury, depending on the number of dental amalgam fillings, were statistically significant (p-trend < 0.01, p-quadratic < 0.01). As a result of multiple regression analysis on the blood mercury concentration of elementary school students, the regression coefficient (beta) of a dental amalgam filling was found to be 0.027 (standard error = 0.014, p = 0.048).
CONCLUSIONS
In children, the dental amalgam fillings were significantly contribute to the concentration of blood mercury. To accurately assess the effect of dental amalgam on the concentration of body mercury, further studies using the concentration of urine mercury are needed.
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Effects of Volatile Organic Compounds, and Formaldehyde on Heart Rate Variability among Elderly People in Seoul
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Jeong Cheol Seo, Mo Yeol Kang, Soo Hun Cho, Youn Hee Lim, Jin Hee Kim, Jong Ryeul Sohn, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2011;23(3):253-260. Published online September 30, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.3.253
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Abstract
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- OBJECTIVES
The purpose of the present study was to investigate the effects of volatile organic compounds, and formaldehyde on heart rate variability among elderly people who are vulnerable to ambient pollution.
METHODS
From May to August of 2009, 57 subjects older than 60 years were recruited in this study. Indoor air pollutants (volatile organic compounds and formaldehyde) were measured by a personal passive sampler. Heart rate variability (HRV) was measured in the sitting position for five minutes and assessed by time-domain and frequency-domain.
RESULTS
Multiple linear regression analysis showed significantly less low-frequency (LF) and high-frequency (HF) associated with elevated benzene levels. Exposure to toluene was associated with decreases in the Standard deviation of the NN intervals (SDNN) and LF. SDNN and LF were negatively associated with the increment of ethylbenzene levels.
CONCLUSIONS
An adverse effect on cardiovascular function caused by volatile organic compounds was observed among the elderly people of Seoul even though indoor air pollutant levels were lower than the yearly average guideline for indoor air quality in Korea.
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Citations
Citations to this article as recorded by - Estimating Benzene Exposure Level over Time and by Industry Type through a Review of Literature on Korea
Donguk Park, Sangjun Choi, Kwonchul Ha, Hyejung Jung, Chungsik Yoon, Dong-Hee Koh, Seunghun Ryu, Soogeun Kim, Dongmug Kang, Kyemook Yoo
Safety and Health at Work.2015; 6(3): 174. CrossRef
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Association between Cadmium and Cognitive Function in the Elderly
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Mo Yeol Kang, Soo Hun Cho, Youn Hee Leem, Jin Hee Kim, Sang Hyuk Bae, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2011;23(3):309-316. Published online September 30, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.3.309
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Abstract
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- OBJECTIVES
We conducted this study to investigate the relationship between the blood concentration of cadmium and cognitive function in elderly Koreans.
METHODS
This research is a part of the Korean Elderly Environmental Panel Study (KEEPS). A total of 403 subjects were enrolled and analyzed from August 2008 through August 2010. Demographic information and medical histories were obtained using a questionnaire. Blood concentration of cadmium and Mini-Mental State Examination (MMSE) with Functional Activities Questionnaire (FAQ) were evaluated for each subject.
RESULTS
The mean age of subjects was 70.67 (SD 5.18, n=403) and 72% were female. The mean blood cadmium level was 1.22 microg/dl (SD 0.56), mean MMSE score was 25.12 out of 30 and mean FAQ score was 2.03 out of 30. Using linear regression analysis to estimate the relationship between blood cadmium concentration and MMSE and FAQ, we observed a significant association between log transformed values of blood cadmium levels and MMSE (p<0.002) or FAQ (p=0.005) scores. After adjusting for age, sex, level of education, alcohol consumption and smoking habits, the relationship between blood cadmium concentration and MMSE and FAQ scores ramained statistically significant (p=0.033 and 0.029, respectively).
CONCLUSIONS
These results suggest that blood cadmium concentration is strongly associated with cognitive function and functional activity in the elderly.
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Citations
Citations to this article as recorded by - Association between heavy metals, high-sensitivity C-reaction protein and 10-year risk of cardiovascular diseases among adult Korean population
Hai Duc Nguyen, Hojin Oh, Ngoc Hong Minh Hoang, Min-Sun Kim
Scientific Reports.2021;[Epub] CrossRef - Associations between Cadmium Exposure and Taste and Smell Dysfunction: Results from the National Health and Nutrition Examination Survey (NHANES), 2011–2014
Yi Zheng, Yun Shen, Zheng Zhu, Hui Hu
International Journal of Environmental Research and Public Health.2020; 17(3): 943. CrossRef - The association between cadmium and lead exposure and blood pressure among workers of a smelting industry: a cross-sectional study
Hyun Chan An, Joo Hyun Sung, Jiho Lee, Chang Sun Sim, Sang Hoon Kim, Yangho Kim
Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef - Does cadmium exposure contribute to depressive symptoms in the elderly population?
Changwoo Han, Youn-Hee Lim, Yun-Chul Hong
Occupational and Environmental Medicine.2016; 73(4): 269. CrossRef
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Association Between Blood Lead Concentration and Computerized Neurobehavioral Performance in Korean Elementary School Students
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Yeon Cheol Kim, Man Joong Jeon, Yun Chul Hong, Chul Gab Lee, Mi Na Ha, Ho Jang Kwon, Joon Sakong
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Korean Journal of Occupational and Environmental Medicine 2011;23(2):183-191. Published online June 30, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.2.183
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Abstract
PDF
- OBJECTIVES
This study was conducted to evaluate association between computerized neurobehavioral performance and blood lead concentration in Korean elementary school students.
METHODS
The subjects were 1,077 elementary school students of Seoul, Busan, Daegu and Gwangju. Blood lead concentration was measured and computerized neurobehavioral performance tests were performed.
RESULTS
Blood lead concentration of the subjects was in the range of 0.20 and 7.39 microg/dl. The geometric mean of the subjects' blood lead concentration was 1.41 microg/dl. As blood lead concentration increased, reaction time to the symbol digit tended to increase significantly and linearly. As a result of LOWESS(locally weighted scatterplot smoothing), increasing reaction time to the symbol digit was observed.
CONCLUSIONS
As blood lead concentration under the CDC (center for disease control and prevention) reference value increased, reaction time to the symbol digit tended to increase. But, as the number of subjects over 3 microg/dl is small, it is difficult to make a definite conclusion. If confounding variables are controlled properly in a follow-up study, we can obtain a more definite conclusion.
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Citations
Citations to this article as recorded by - Association of heavy metal complex exposure and neurobehavioral function of children
Minkeun Kim, Chulyong Park, Joon Sakong, Shinhee Ye, So young Son, Kiook Baek
Annals of Occupational and Environmental Medicine.2023;[Epub] CrossRef - Performance assessment on the Korean Computerized Neurobehavioral Test using a mobile device and a conventional computer: an experimental study
Young Seok Byun, Sung Kyu Park, Joon Sakong, Man Joong Jeon
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef - The association between lead concentration in the blood and neurobehavioral performance of children
Dae-Seon Kim, Seungchul Ahn, Seungdo Yu, Eun-Hee Lee
Toxicology and Environmental Health Sciences.2012; 4(2): 87. CrossRef - Evaluation of reliability of computerized neurobehavioral tests in Korean children
Kyeong-Soo Lee, Man-Joong Jeon, Tae-Yoon Hwang, Chang-Yoon Kim, Joon Sakong
NeuroToxicology.2012; 33(5): 1362. CrossRef
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Association of Blood Mercury Level and Neurobehavioral Performance in Korean Elementary School Students
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Joon Sakong, Man Joong Jeon, Sung Ho Yun, Yun Chul Hong, Chul Gab Lee, Young Ki Kim, Mina Ha, Ho Jang Kwon
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Korean Journal of Occupational and Environmental Medicine 2010;22(4):324-330. Published online December 31, 2010
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DOI: https://doi.org/10.35371/kjoem.2010.22.4.324
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Abstract
PDF
- OBJECTIVES
This study was conducted to examine the effect of blood mercury on neurobehavioral performance in Korean elementary school students.
METHODS
We measured the blood mercury concentration in 1,077 elementary school students from Seoul, Busan, Daegu and Gwangju, then the students underwent computerized neurobehavioral test.
RESULTS
The mean concentration of blood mercury of study subjects was 2.10 microg/L. An increased blood mercury was associated with an increased reaction time in digit addition and symbol digit.
CONCLUSIONS
The blood mercury concentration of study subjects was very high compared to findings in a foreign country. We found several associations between blood mercury level and neurobehavioral performance.
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Citations
Citations to this article as recorded by - Performance assessment on the Korean Computerized Neurobehavioral Test using a mobile device and a conventional computer: an experimental study
Young Seok Byun, Sung Kyu Park, Joon Sakong, Man Joong Jeon
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef - Evaluation of reliability of computerized neurobehavioral tests in Korean children
Kyeong-Soo Lee, Man-Joong Jeon, Tae-Yoon Hwang, Chang-Yoon Kim, Joon Sakong
NeuroToxicology.2012; 33(5): 1362. CrossRef
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Area-Based Occupational Disease Surveillance in Incheon, Korea: Results of an 11-year Data Survey
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Jeong Hoon Kim, Shin Goo Park, Jong Han Leem, Jong Uk Won, Sang Hwan Han, Soo Young Chung, Sang Hoon Kim, Hwan Cheol Kim, Yun Chul Hong, Cheol Woo Kim, Chang Hwan Kim, Dong Hyun Kim, Dong Hoon Lee, Seung Jun Lee, Young Joong Kang, Woo Seok Kwak, Jeongbae Rhie
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Korean Journal of Occupational and Environmental Medicine 2010;22(3):183-199. Published online September 30, 2010
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DOI: https://doi.org/10.35371/kjoem.2010.22.3.183
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Abstract
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- OBJECTIVES
Between Jan 1998 and Dec 2008, area-based occupational disease surveillance in Incheon was used to collect data on occupational diseases. The long-term data was used to estimate the scale of disease, to analyze disease characteristics, and to achieve surveillance in order to determine development tasks.
METHODS
For a period of 11 years, occupation-related disease surveillance was performed on an annual basis for employees of Incheon industries. All cases of occupational disease were reported by means of the Incheon Occupational Disease Information Network (IODIN) web site, downloaded, and analyzed, subsequently.
RESULTS
Between Jan 1998 and Dec 2008, 1577 cases of occupational disease were reported. Of these, there were 1043(66.1%) cases of occupational musculoskeletal disorders, 172(10.9%) cases of occupational asthma, 162(10.3%) cases of occupational dermatoses, 135(8.6%) cases of occupationally-related cancers, 30(1.9%) cases of pneumoconiosis, 27(1.7%) cases of toxic hepatitis, and 8(0.5%) cases of occupational neuronal disease.
CONCLUSION
In the Incheon area, small and medium industries comprise 99% of business. The composition of the industry by category, in Incheon, is similar to the country on the whole. In actually, the data on occupational diseases in Korea are almost workers' compensation data. Thus, the survey of occupational disease based in Incheon, Korea, can serve as an estimate of the trends and size of the occupational disease throughout the entire country.
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Citations
Citations to this article as recorded by - Repeated measures study of the association between musculoskeletal symptoms and mental health in subway workers
Yun-Sik CHO, Jae-Bum PARK, Soojeong KIM, Kyungjong LEE
Industrial Health.2019; 57(6): 721. CrossRef - Work-Related Asthma in Korea - Findings from the Korea Work-Related Asthma Surveillance (KOWAS) program, 2004-2009
Soon-Chan Kwon, Jaechul Song, Yong-kyu Kim, Geoffrey M. Calvert
Allergy, Asthma & Immunology Research.2015; 7(1): 51. CrossRef
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Hot Tub Lung Due to Mycobacterium Avium Complex in a Public Bath
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Chung Won Kang, Yun Kyung Chung, Hye Eun Lee, Eun A Kim, Yun Chul Hong, Soo Hun Cho
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Korean Journal of Occupational and Environmental Medicine 2010;22(2):166-172. Published online June 30, 2010
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DOI: https://doi.org/10.35371/kjoem.2010.22.2.166
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Abstract
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- BACKGROUND
Hot tub lung is a hypersensitivity pneumonitis caused by nontuberculous mycobacteria (NTM); the primary causative agent is Mycobacterium avium complex (MAC) post contaminated water exposure. Recently, 2 cases of hot tub lung were found in public bath bodyscrubbers working in Korea. However, the disease causing NTM was not identified in these cases. Here, we reported one case, along with clinical diagnostic approach to occupational medicine throughout worksite investigation.
CASE
A 53 year-old woman working in the public bath for 13 months' duration developed shortness of breath. She had been cleaning the locker room, several pools and floors every day, and using scrubbers with detergent and warm water. After examination, the patient was diagnosed with hypersensitivity pneumonitis based on high resolution computerized tomography and lung biopsy. Because the Mycobacterium avium was identified in both the patient's sputum and the warm pool, she was diagnosed with hot tub lung due to MAC.
CONCLUSION
Hot tub lung due to MAC was confirmed in public bath housekeeper. However, few cases have been reported, even though there are many cases. To prevent damages caused by hot tub lung, general environmental management such as ventilation and cleaning is important for bath operators. Likewise, awareness needs to be increased in workers with potential NTM environmental exposure and in clinicians through education about hot tub lung in order to reduce adverse harm from misdiagnosis and mistreatment of tuberculosis.
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The Effects of Particulate Matter on Respiratory Function of Schoolchildren in Jeju: A Panel Study
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Jae Yong Moon, Su Young Kim, Kwang Sik Park, Ho Kim, Chung Won Kang, Hyun Seung Park, Soo Hun Cho, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2009;21(3):218-224. Published online September 30, 2009
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DOI: https://doi.org/10.35371/kjoem.2009.21.3.218
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Abstract
PDF
- OBJECTIVE: To evaluate the changes in respiratory function associated with daily changes in particulate pollution.
METHODS
A total of 105 healthy schoolchildren of fourth and fifth grade elementary school age performed peak expiratory flow rates (PEFR) during 2 periods (May 14~June 15, Oct 22~Nov 23). We monitored concomitant ambient particulate matter (PM) levels during the periods.
RESULTS
An elevation PM(10) level of 1 microgram/m) led to decreases in PEFR of 0.20 L/min. A 1 microgram/m3 elevation of PM(2.5) led to a decrease of 0.36 L/min in PEFR. In addition, 1 day lag was associated with PM(10) levels and PEFR changes, and PM(2.5) showed the same result. The metal levels determined at PM(10) and PM(2.5) were found to be associated with decreased respiratory function.
CONCLUSIONS
An association between respiratory function and particulate pollution was observed when particulate pollutant levels were lower than the yearly average National Ambient Air Quality Standard in the Korea(50 microgram/m3).
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Citations
Citations to this article as recorded by - Diesel Exhaust Particle Exposure and its Pulmonary Function Effects
Yong-Jin Lee, Da-Hye Kim, Soo-Hwan Kim, Jeong-Soo Kim, Dong-Chun Shin, Young-Wook Lim
Journal of Korean Society for Atmospheric Environment.2016; 32(5): 457. CrossRef
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The Clinical Importance of an Increase in Serum Gamma-glutamyltransferase Concentration
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Joo Youn Shin, Yong Kyu Kim, Shin Goo Park, Jee Na Lee, Hwan Chul Kim, Jong Han Leem, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2005;17(1):1-9. Published online March 31, 2005
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DOI: https://doi.org/10.35371/kjoem.2005.17.1.1
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Abstract
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- OBJECTIVES
Incresed gamma-glutamyltransferase (GGT) concentration has mainly been used as a biologic marker of alcohol drinking and liver diseases. However, some recent reports have suggested that serum GGT concentration may be an early biomarker of oxidative stress and associated with chronic diseases like hypertension, DM, hyperlipidemia, CHD, stroke etc. In this study, we analysed the factors associated with increased serum GGT level and evaluated the clinical application of serum GGT in predicting the risk of chronic diseases.
METHODS
The data were collected from 15,546 periodic health examinations, 9,660 males and 5,886 females, done at one university hospital from 2001 to 2003. We analysed self-questionnaire, physical examination and laboratory data. Statistical analyses(t-test, ANOVA, Pearson's correlation analysis, multiple regression analysis and logistic regression analysis) were done by SPSS for windows 10.0.
RESULTS
Mean serum GGT levels were quite different according to age, sex, BMI, smoking and alcohol drinking (all P-value < 0.001), but were not different by regular vitamin intake or not (P-value=0.117). There was significant correlation between serum GGT level and the variables (of age, BMI, blood pressure, Hb, fasting blood sugar, total cholesterol, AST and ALT) (all P-value < 0.001). In sex-specific multiple regression analysis, increased serum GGT level was significantly associated with age, alcohol drinking, smoking, blood pressure, fasting blood sugar and ALT in males (all P-value < 0.001), and with age, alcohol drinking, smoking, Hb, blood pressure, total cholesterol and ALT in females (all P-value < 0.05). In sex-specific logistic regression analysis, increased serum GGT level was significantly associated with risk of 'clinical abnormalities'. This risk increased about 13-fold in males and 4.6-fold in females for serum GGT level over the third quatile, compared with under the first quartile.
CONCLUSIONS
Serum GGT level is increased not only by alcohol drinking or liver diseases, but also by many other factors associated with chronic diseases and behavioral factors. Thus many factors should be considered in evaluating an increase in GGT level, even when within the upper normal range. Serum GGT level may be a predictor for the early development of chronic diseases.
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Citations
Citations to this article as recorded by - The Association of Central Obesity with Type 2 Diabetes among Koreans according to the Serum Gamma-Glutamyltransferase Level: Korean Genome and Epidemiology Study
Ji-Yeon Shin, Jun-Hyun Hwang, Jin-Young Jeong, Sung-Hi Kim, Jai-Dong Moon, Sang-Chul Roh, Young-Wook Kim, Yangho Kim, Jong-Han Leem, Young-Su Ju, Young-Seoub Hong, Eun-Hee Ha, Yong-Hwan Lee, Duk-Hee Lee, Dong-Hyun Kim
Journal of Preventive Medicine and Public Health.2009; 42(6): 386. CrossRef
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Prevalence of Occupational Asthma in TDI-Exposed Workers
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Hyoung Ryoul Kim, Cheol Woo Kim, Yun Chul Hong, Hyung Joon Chun, Chi Nyon Kim, Hyun Soo Kim, Jee Na Lee, Joo Yeon Shin, Dong Hee Koh, Jaehoon Roh
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Korean Journal of Occupational and Environmental Medicine 2004;16(2):191-199. Published online June 30, 2004
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DOI: https://doi.org/10.35371/kjoem.2004.16.2.191
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Abstract
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- OBJECTIVES
This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers.
METHODS
We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests.
RESULTS
Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma, and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1%). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test.
CONCLUSIONS
The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.
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Occupational Allergic Contact Dermatitis Like Erythema Multiforme Induced by Bolivian Rosewood
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Joo Youn Shin, Yun Chul Hong, Jong Han Leem, Shin Goo Park, Jee Na Lee, Hwan Chul Kim
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Korean Journal of Occupational and Environmental Medicine 2004;16(2):220-226. Published online June 30, 2004
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DOI: https://doi.org/10.35371/kjoem.2004.16.2.220
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Abstract
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- BACKGROUND
Woods are capable of causing allergic or irritant contact dermatitis which typically occurs on exposed areas. Because Bolivian rosewood exclusively contains the strong sensitizer R-3,4-dimethoxydalbergione, an increasing number of cases of irritant and allergic contact dermatitis has been reported.
CASE
REPORT: A 49-year-old, male, wood worker, who handled a variety of woods, developed allergic contact dermatitis. A patch test confirmed a positive reaction to one of the exotic woods, Bolivian rosewood. Allergens found in Bolivian rosewood caused this patient's dermatitis, which cleared when he avoided this wood.
CONCLUSION
Exotic woods such as Bolivian rosewood can induce occupational contact dermatitis. Measures to lower the incidence of work-related dermatitis are needed in the workplace. Especially, when cutting or sanding woods, workers should wear proper personal protection.
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Citations
Citations to this article as recorded by - Occupational Skin Diseases in Korea
Yeon-Soon Ahn, Min-Gi Kim
Journal of Korean Medical Science.2010; 25(Suppl): S46. CrossRef
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The effect of Smoking and Residential environment on Urinary 2-naphthol
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Jee Na Lee, Jong Han Leem, Shin Goo Park, Joo Yeun Shin, Kwan Hee Lee, Yun Chul Hong, Hun Kim, Chul Ho Lee
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Korean Journal of Occupational and Environmental Medicine 2004;16(1):82-91. Published online March 31, 2004
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DOI: https://doi.org/10.35371/kjoem.2004.16.1.82
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Abstract
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- OBJECTIVES
To evaluate the association of urinary 2-naphthol level and air pollution caused by exposure to smoking, traffic and residential factors.
METHODS
The study subjects consisted of 300 university students in Incheon. The questionnaires concerning subject characteristics, smoking amount, traffic, distance between housing and main road, heating and cooking fuel including urinary cotinine levels were checked.
RESULTS
There was not any significant association between urinary 2-naphthol level and age, sex, body mass index, distance from mainroad, traffic, heating and cooking fuel. The urinary 2-naphthol level was higher in smokers or high urinary cotinine level group(p=0.0001)than in nonsmokers or low urinary cotinine group. After adjusting for age, sex, and body mass index in the basic model, the 2-naphthol level was also higher in the smokers or high urinary cotinine level group, too(p<0.0005). The model included both traffic and residential variables and it had a good fitness as compared to other models.
CONCLUSIONS
It has been known that as one of PAH metabolites, urinary 2-naphthol is a respiration-selective biological marker. We showed that tabacco smoking has a much stronger effects on urinary 2-naphthol levels than when subjects were exposed to air pollution, such as traffic, and other residential factors at the same time.
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Characteristics of Occupational Asthma Reported by Surveillance System in Incheon
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Hyoung Ryoul Kim, Yun Chul Hong, Jong Han Leem, Jong Uk Won, Hyung Joon Chun, Jee Na Lee, Joo Yeon Shin
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Korean Journal of Occupational and Environmental Medicine 2003;15(4):344-350. Published online December 31, 2003
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DOI: https://doi.org/10.35371/kjoem.2003.15.4.344
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Abstract
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- OBJECTIVES
This study was carried out to estimate the magnitude of occupational asthma and to determine its characteristics.
METHODS
We collected and analyzed 121 cases of occupational asthma reported by a surveillance system in Incheon for 5 years. The cases were classified according to industry and causing gent. We attached the data to worker's compensation records to establish the degree of agreement between the two sources.
RESULTS
The industry of musical instrument manufacture was the most common (31 cases, 25.6%), followed by furniture manufacture, dye making, and machinery manufacture. TDI was the most common causing agents (52 cases, 43%), followed by reactive dye, wood dust, and organic dust. There was poor agreement with the worker's compensation records (2 cases, 8%).
CONCLUSIONS
TDI and reactive dyes were the major materials causing occupational asthma. Most cases reported by the surveillance system were not applied to the worker's compensation system. Therefore, the surveillance system should be used to estimate the magnitude of occupational asthma and to determine its characteristics.
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Citations
Citations to this article as recorded by - Clinical Importance of Work-Exacerbated Asthma: Findings From a Prospective Asthma Cohort in a Highly Industrialized City in Korea
Woori Jo, Kwang Won Seo, Hwa Sik Jung, Chui Yong Park, Byung Ju Kang, Hyeon Hui Kang, Seung Won Ra, Yangjin Jegal, Jong Joon Ahn, Soon Eun Park, Moon Sik Jung, Ju Ik Park, Eun Ji Park, Chang Sun Sim, Tae-Bum Kim, Taehoon Lee
Allergy, Asthma & Immunology Research.2021; 13(2): 256. CrossRef - Work-Related Asthma in Korea - Findings from the Korea Work-Related Asthma Surveillance (KOWAS) program, 2004-2009
Soon-Chan Kwon, Jaechul Song, Yong-kyu Kim, Geoffrey M. Calvert
Allergy, Asthma & Immunology Research.2015; 7(1): 51. CrossRef
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Effect of Commuting Time on Male Worker's Serum Gamma-glutamyltransferase Level
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Sang hoon Kim, Jee Na Lee, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2002;14(4):418-425. Published online December 31, 2002
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DOI: https://doi.org/10.35371/kjoem.2002.14.4.418
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Abstract
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- OBJECTIVES
Alcohol drinking, obesity, and reduced physical activity are commonly related to oxidative stress, which induces plasma membrane-bound protein damage in hepatic cells and elevates serum gamma-GTP. We have a hypothesis that a long commuting time may induce oxidative stress. This study was undertaken to investigate the relationship between commuting time and serum gamma-GTP level.
METHODS
Questionnaires were administered to 717 male workers who had worked at Kimpo airport until the year 2000,and had then moved to Incheon airport and were working there in 2002. The questionnaire included items concerning commuting time, sleeping time and alcohol consumption. Physical examination and laboratory data were also collected.
RESULTS
Serum gamma-GTP level was significantly and positively correlated with commuting time, body mass index, systolic blood pressure,diastolic blood pressure, hemoglobin, glucose, total cholesterol, AST, ALT and alcohol consumption. Multivariate regression analysis demonstrated that serum gamma-GTP level is significantly associated with commuting time, after considering the other covariates.
CONCLUSIONS
Commuting time is one of the factors that affects serum gamma-GTP level in male workers.
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The Analysis of Disease Distribution and Referral Routes of Patients in an Occupational and Environmental Medicine Clinic of a University Hospital
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Sang Hoon Kim, Jee Na Lee, Jong han Leem, Yun Chul Hong
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Korean Journal of Occupational and Environmental Medicine 2002;14(4):448-458. Published online December 31, 2002
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DOI: https://doi.org/10.35371/kjoem.2002.14.4.448
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Abstract
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- OBJECTIVES
The occupational & environmental medicine clinic plays an important role in the growth and advance of occupational & environmental medicine.This study analyzes the disease distribution and referral routes of patients in an occupational & environmental medicine clinic of a university hospital.
METHODS
843 Agent Orange cases and 839 other cases were treated in the clinic over a period of 4 years. The Agent Orange cases were excluded from this study.Distributions of age, sex, disease and referral route were examined according to the medical records of the hospital.
RESULTS
654 of the patients in the study population were male (77.9 %)and 185 were female (22.1 %).The most common age group consisted of patients in their forties.The number of cases has been increasing annually(1998,146 cases;1999,174 cases; 2000, 247 cases; 2001, 272 cases). The source of the cases were as follows: health examination, 548(65.4 %); health management service, 132(15.7 %);self-referral,125(14.9 %); physicians in other hospitals, clinics, 18 (2.1 %); and physicians in other clinic in the hospital, 16(1.9 %). The most commonly occurring disease was liver disease(28.6 %),followed by respiratory disease(12.8 %), gastroenteric disease (10.3 %)and musculoskeletal disease (8.7%).When the clinic was first opened, most cases came through 'health examination'. Subsequently the number of cases arising from 'self-refferal' and 'health management services' were increased.The disease distribution has also changed as the referral route distribution evolved.
CONCLUSIONS
In order to expand the work of the clinic, primary cares for patients who came from 'health examination' will be needed to settle down the clinic at the beginning. Thereafter,specialized services need to be developed for cases originating from 'self-refer-ral' and from referral by other organizations.Increasing the number of cases needs to go hand in hand with the development of good management skills.
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Local occupational disease surveillance system in Korea: Current status and issues
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Jong Han Leem, Seong Sil Chang, Seong Ah Kim, Jai Dong Moon, Chang Ho Chae, Yun Chul Hong, Soo Young Kim, Jin Seok Kim, Young Wook Kim, Sang Hwan Han, Hae Sook Lee, Jong Uk Won, Dong Bin Song, Eun Hee Ha, Seong Kyu Kang
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Korean Journal of Occupational and Environmental Medicine 2001;13(2):101-115. Published online June 30, 2001
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DOI: https://doi.org/10.35371/kjoem.2001.13.2.101
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Abstract
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- No abstract available.
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Citations
Citations to this article as recorded by - Management System of Occupational Diseases in Korea: Statistics, Report and Monitoring System
Kyung Yong Rhee, Seong Weon Choe
Journal of Korean Medical Science.2010; 25(Suppl): S119. CrossRef
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18
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The Present Status and Perspective of Nationwide Occupational Diseases Surveillance System
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Seong Kyu Kang, Young Koo Jee, Yeon Soon Ahn, Hyoung Ok Kim, Mi Na Ha, Ho Jang Kwon, Nam Jong Paik, Seong Ah Kim, Yun Chul Hong, Jai Yong Kim, Dae Hee Kang, Hye Sun Jung, Eun Hee Ha
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Korean Journal of Occupational and Environmental Medicine 2001;13(2):116-126. Published online June 30, 2001
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DOI: https://doi.org/10.35371/kjoem.2001.13.2.116
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Abstract
PDF
- No abstract available.
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Citations
Citations to this article as recorded by - Cohort Profile: Gachon Regional Occupational Cohort Study (GROCS)
Wanhyung Lee, Yongho Lee, Junhyeong Lee, Uijin Kim, Eunsun Han, Seunghon Ham, Won-Jun Choi, Seong-Kyu Kang
Safety and Health at Work.2022; 13(1): 112. CrossRef - Occupational Skin Diseases in Korea
Yeon-Soon Ahn, Min-Gi Kim
Journal of Korean Medical Science.2010; 25(Suppl): S46. CrossRef - Occupational Diseases in Korea
Seong-Kyu Kang, Eun A Kim
Journal of Korean Medical Science.2010; 25(Suppl): S4. CrossRef - Asbestos-related Occupational Cancers Compensated under the Industrial Accident Compensation Insurance in Korea
Yeon-Soon AHN, Seong-Kyu KANG
Industrial Health.2009; 47(2): 113. CrossRef - Occupational Infectious Diseases among Korean Health Care Workers Compensated with Industrial Accident Compensation Insurance from 1998 to 2004
Yeon-Soon AHN, Hyun-Sul LIM
Industrial Health.2008; 46(5): 448. CrossRef - Occupational hand–arm vibration syndrome in Korea
Cheolin Yoo, Ji-Ho Lee, Choong-Ryeol Lee, Yangho Kim, Hun Lee, Younghee Choi, Young Wook Kim, Chang Ho Chae, Hyokyoung Kim, Sang Baek Koh, Euna Kim, Lu Jin Lee, Kiyoung Lee
International Archives of Occupational and Environmental Health.2005; 78(5): 363. CrossRef
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25
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Occupational Disease Surveillance System in U.S.A. and U.K.
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Seong Kyu Kang, Jae Chul Hong, Yun Chul Hong, Seong Ah Kim
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Korean Journal of Occupational and Environmental Medicine 2001;13(1):1-9. Published online March 31, 2001
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DOI: https://doi.org/10.35371/kjoem.2001.13.1.1
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Abstract
PDF
- No abstract available.
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Occupational Disease Surveillance System: Planning and Management
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Soo Hun Cho, Yun Chul Hong, Jong Han Leem, Seong Sil Chang, Byung Chul Chun
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Korean Journal of Occupational and Environmental Medicine 2001;13(1):10-17. Published online March 31, 2001
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DOI: https://doi.org/10.35371/kjoem.2001.13.1.10
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Abstract
PDF
- No abstract available.
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Citations
Citations to this article as recorded by - Management System of Occupational Diseases in Korea: Statistics, Report and Monitoring System
Kyung Yong Rhee, Seong Weon Choe
Journal of Korean Medical Science.2010; 25(Suppl): S119. CrossRef
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31
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Feasibility Study of Constructing an Occupational Disease Surveillance System in Inchon
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Jong Han Leem, Yun Chul Hong, Hyesook Park, Eun Hee Ha
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Korean Journal of Occupational and Environmental Medicine 1999;11(2):241-253. Published online June 30, 1999
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DOI: https://doi.org/10.35371/kjoem.1999.11.2.241
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Abstract
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- The occurrence of occupational illnesses and injuries has been seriously underestimated in Korea. This underdiagnosis and underreporting of occupational illnesses and injuries subsequently contribute to difficulties in performing effective control of occupational hazards and implementing intervention programs to protect workers. An Inchon model for an occupational disease surveillance system was constructed using multiple data sources. Available data were obtained from medical providers' reports, hospital medical records, medical examination data of employees, and environmental measurement data. This Jnchon model was constructed with the following procedure: 1. assembled multidisciplinary staff 2. geographic targeting was to Inchon 3. established community liaison 4. collected related data to establish the magnitude of problem 5. selected, recruited, and trained case reporters 6. developed mechanisms and guidelines for reporting 7. received, screened, and prioritized case reports 8. analyzed data from case reports and field investigations 9. made and disseminated recommendations 10. evaluated the feasibility of the system. An information system based on the Internet for the occupational disease surveillance was also constructed to support the case reporting of occupational diseases. 133 cases of occupational diseases were collected in Inchon from 1 January to 31 December 1998. These cases included cumulative traumatic disorder, occupational asthma, occupational contact dermatitis, allergic pneumonitis, occupational cancer, noise-induced hearing loss, and pneumoconiosis. These data were different from the previously reported data The occurrence pattern of occupational diseases obtained from this surveillance system will be useful for preventing occupational hazards and for enforcing occupational disease prevention programs. Our experiences in establishing this surveillance system may be also used in other regional settings.
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The Development of Health Risk Appraisal at the Worksite
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Eun Hee Ha, Heui Sug Jo, Hye Sook Park, Yun Chul Hong, Hyun Sul Lim, Gyu Chul Chung, Yong Ae Lee
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Korean Journal of Occupational and Environmental Medicine 1998;10(4):548-561. Published online December 31, 1998
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DOI: https://doi.org/10.35371/kjoem.1998.10.4.548
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Abstract
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- Health Risk Appraisal(HRA) is usually defined as a process by which we expect of individual's chances of death or acquiring specific diseases within a defined period of time. The concept of worksite as an area of health maintenance and promotion is newly developing. Our movement for health promotion of employees has been increasingly known in the worksite. The aim of this study is to develop health risk appraisal tools about health promotion at the worksite for employees. We performed this study by two steps: one step was to develop a HRA questionnaire of worksites in Korea, another was to evaluate the reliability of the questionnaire. For developing HRA questionnaire, we reviewed scientific examples at first, and then weighted the score by delphi. To evaluate the reliability of developed questionnaire, we carried out survey by test-retest method. A total of 131 employees completed HRA questionnaire on two times. The results are as follows. The total score of health risk in unhealthy workers was higher than that of healthy workers. The range of test-retest reliability of responses to the questionnaire was 0.57-0.94. Therefore it seems that this questionnaire was very suitable to assess the health behavior of workers. In conclusion, the developed HRA questionnaire can be used as a tool for evaluating health behavior and for providing health counseling materials.
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Quality Assessment of Group Occupational Health Service for Small and Medium Scale Enterprises in Korea
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Sunmean Kim, Soo Hun Cho, Chang Yup Kim, Eun Hee Ha, Yun Chul Hong, Ho Jang Kwon, Mi Na Ha, Sang Hwan Han, Young Su Ju
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Korean Journal of Occupational and Environmental Medicine 1998;10(1):71-82. Published online February 28, 1998
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DOI: https://doi.org/10.35371/kjoem.1998.10.1.71
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Abstract
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- Group occupational health service programme started in 1990 is one of the measures to cope with limited human and financial resources in occupational health. The programme has expanded rapidly to include 52 institutions, private as well as public, all over the country. In spite of its potential impact on health of employees and practice of occupational health in small and medium sized industries, comprehensive evaluation in terms of quality has not been tried. This study has aims to develop the criteria to assess the quality of newly developed group occupational health service programme, and to investigate the quality of institutions, and finally to develop policies for the quality improvement. 1) Criteria development : By defining occupational health services, in particular for small and medium sized industries, as one of the primary health care, followings are included as core elements of qualitative occupational health programme ; accessibility, continuity, comprehensiveness, technical quality, intersectoral collaboration, emphasis on preventive services, community participation, and adequacy. Again each element is divided into five major components of national health system infrastructure developed by the World Health Organization ; development of health resources, organized arrangement of resources, delivery of health care, economic support, and management. In turn, each component is categorized into three aspects of quality assessment, structure, process and outcome. Expert panel selected several criteria for each category to evaluate the programme. Criteria were modified according to each group of interviewees, to produce two sets of questionnaire, one for chief operating officer and another for nurses in the institutions, and the chief operating officer and workers in the workplace. 2) Subject : Of all 52 institutions, 25 voluntarily participated in the survey. At individual institution, chief operating officer and practicing nurses were interviewed in depth. After intensive education for interviewees, every interview was performed with standardized guideline and questionnaire. The quality of the 'Group occupational health service programme' was found to be lower than expected. Especially In continuity, comprehensiveness, technical quality, community participation and adequacy, lower quality in structural aspect was commonly identified throughout all the institutions. Quality in terms of accessibility and continuity highly varied among institutions. To improve quality of the programme, more comprehensive and systematic programme such as accreditation has to be introduced. In addition, human resources, governmental fund and information systems for individual workers are to be developed. As a long range plan, integration of occupational health services into the national health systems and pooling of financial resources and planned allocation should be considered.
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Citations
Citations to this article as recorded by - The roles of doctors, nurses, and industrial hygienists in the healthcare management services in Korea: a comparison of the opinions of specialized health management institutions and entrusted enterprises
Bo-Young Jang, Dong-Mug Kang, Young-Ki Kim, Se-Young Kim, Kyung-Sun Ko
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef - Relationship between occupational injuries and the provision of safety and health information: data from the 4th Korean working conditions survey
Ju-il Seo, Gab-Sik Shin, Min Gi Kim, Young-Sun Min
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef - Practice status of specialized agencies for occupational health management of small- to medium-size enterprises and the factors improving their performance: a cross-sectional survey study
Saerom Lee, Jun-Pyo Myong, Eun-A Kim, Huisu Eom, Bowha Choi, Young Joong Kang
Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef - Validation of Performance Indicators for Evaluation of Workplace Health Promotion
Seung Hee Ho, Young Moon Chae
American Journal of Health Promotion.2015; 29(6): 402. CrossRef
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34
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Job Performance of Occupational Health Personnel
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Yun Chul Hong, Eun Hee Ha, Kyung Ja Jun, Young Man Rho, Hye Sook Park, Heui Sug Jo, Hun Jae Lee, Mi Ran Yang
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Korean Journal of Occupational and Environmental Medicine 1997;9(3):496-507. Published online October 31, 1997
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DOI: https://doi.org/10.35371/kjoem.1997.9.3.496
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Abstract
PDF
- No abstract available.
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Citations
Citations to this article as recorded by - Economic Evaluation of a Workplace Occupational Health Nursing Service: Based on Comparison with Atmospheric Environment Managing Engineer
Hye-Sun Jung, Bokim Lee
Journal of Korean Academy of Nursing.2013; 43(4): 507. CrossRef - Job Analysis with IPA (Importance-Performance Analysis) based on the Qualification of Occupational Health Managers Working in Manufacturing Work-sites
Jung-Ah Yun, Soon-Lae Kim, Hye-Sun Jung
Korean Journal of Occupational Health Nursing.2013; 22(2): 159. CrossRef - The Effect of Korean Occupational Health Nurses' Work Conditions on their Performance
Min Kwon, Soon-Lae Kim, Hye-Sun Jung, Hee-Girl Kim, Kyung-Lim Kim
Korean Journal of Occupational Health Nursing.2011; 20(1): 83. CrossRef - Occupational Health Nurses' Role Experiences
Kyung-Ja June, Hea-Ju Joo, Young-Mi Kim
Korean Journal of Occupational Health Nursing.2011; 20(3): 250. CrossRef
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17
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Phototoxic Dermatitis by Coal Tar Containing Paint
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Yun Chul Hong, Eun Hee Ha, Hye Sook Park
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Korean Journal of Occupational and Environmental Medicine 1997;9(2):267-274. Published online June 30, 1997
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DOI: https://doi.org/10.35371/kjoem.1997.9.2.267
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Abstract
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- Many workers who used coal tar containing paints in shipyard industry have dermatitis, but the etiology is not known well. Our research is to fond out the etiology of the dermatitis and to provide proper management. Methods of this research are comprised of 3 steps. First, we diagnosed dermatitis by questionnaire and dermatologic examination and evaluated air level of coal tar pitch volatiles in workplace. Second, we confirmed coal tar phototoxicity by in vitro cell experiments. Third, we evaluated the effects of intervention. The results were as follows ; Questionnaire survey showed that the lesions of dermatitis were mainly on the sun exposed area and the symptoms were strongly associated with season, weather, and time. Air levels of coal tar pitch volatiles in workplace were higher than NIOSH standard (0.1 mg/m(3), cyclohexane solubles). Inhibitory effects of cellular proliferation by coal tar containing paints and UVA (365nm) exposure showed coal tar phototoxicity. Intervention was done by UV barrier cream(BPF 30) and 72.7% workers who applied UV barrier cream improved after 2 months later. Conclusively, the etiology of dermatitis of shipyard workers who used coal tar containing paint was coal tar phototoxicity, and this dermatitis would be protected by UV barrier cream.
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Citations
Citations to this article as recorded by - Overview of occupational cancer in painters in Korea
Jun-Pyo Myong, Younmo Cho, Min Choi, Hyoung-Ryoul Kim
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
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31
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A Survey of Working Conditions of Migrant Workers
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Yun Chul Hong, Eun Hee Ha
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Korean Journal of Occupational and Environmental Medicine 1996;8(1):1-14. Published online February 29, 1996
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DOI: https://doi.org/10.35371/kjoem.1996.8.1.1
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Abstract
PDF
- The number of migrant workers staying in Korea is 73,250 August 1994 now by the data which Economic Planning Agency presented to the National Assembly. Industrial trainees were reported to be 17,640 and illegal stayers were 55,610 but many migrant workers did not seem to be included. There are some reports which described the unfulfillment of their basic right such as discrimination of wage, delay of payment, long working hours, enforced work, but working conditions, work environment and their health were not surveyed well. Therefore this survey is to study their situation such as working conditions, work environment, health and living conditions as well as general characteristics. Questionnaire was written by plain English and was made of closed question mainly. Finally 185 persons completed the questionnaire. The results are as follows; 1) The general characteristics are following: ages are mostly between 20 and 29 years old, and males are more than females, and mostly unmarried. Many were students in their countries and their education levels were high. 2) Many persons; were introduced to Korea by native broker. Total cost for coming to Korea was mostly over $1,000 and many paid over $2,000. Their staying period in Korea is mostly over 2 years arid many persons think their status uneasy. The most important purpose for coming to Korea is to earn money. 3) Many are working in garment factories but most factories are small scale: ones below 20 employees. Most are working over 10 hours a day. The average income is $480 and that is about 54.8% of average income of Korean workers. Unpaid salaries are about $921 per each worker. 4) 15.8% of migrant workers answered to have experienced industrial accidents. Their health status seems to be worse after coming to Korea. The resident environment was very poor. We knew that migrant workers' situation was very bad considering their working conditions, work environment, health and living conditions. Therefore, employment policy of migrant workers must be reviewed immediately and good working conditions must be provided to them as soon as possible.
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Citations
Citations to this article as recorded by - Occupational Characteristics and Health Status of Vietnamese Male Migrant Workers in the Republic of Korea
Ohwi Kwon, Ji-Hun Song, Jeong-Ok Kong, Seong-Won Ma, Young Shin Lee, Joonho Ahn
Safety and Health at Work.2023; 14(3): 267. CrossRef - I never expected to be a disabled person in another country: the stories of migrant workers with acquired disabilities in Korea
Kyung Mee Kim
Disability & Society.2011; 26(5): 553. CrossRef
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29
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DNA-Protein Crosslinks Formation by Benzo[a]pyrene and the Metabolites in BALB/3T3 cells
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Yun Chul Hong, Hun Jae Lee
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Korean Journal of Occupational and Environmental Medicine 1996;8(1):66-72. Published online February 29, 1996
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DOI: https://doi.org/10.35371/kjoem.1996.8.1.66
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Abstract
PDF
- Carcinogenic materials used in. occupational setting are thought to induce cancer by acting on DNA. BenzoCa)pyrene and the metabolites activated by the rat microsomal fraction were treated to the BALB/3T3 cells to see the formation of DNA-Protein Crosslinks (DPCs) and the repair. We measured the DPCs by the K-SDS assay according to Costa. The results are as follows: 1) The cytotoxicity results showed that viable cells were decreased by the increase of the dose of benzo[a]pyrene and microsomal activated metabolites and the metabolites treated cells showed more cytotoxicity. 2) The amounts of protein-crosslinked DNA in control cells are 690 ng/ml. The amounts were increased to 920 ng/ml in benzoCa)pyrene 0.1 microgram/ml treated cells, 720 ng/ml in benzo[a]pyrene 1 microgram/ml treated cells, 1,243 ng/ml in benzo[a]pyrene 10 microgram/ml, treated cells. The DPCs were measured higher in the metabolites treated cells than the benzo[a]pyrene treated cells 3) The DPCs were highest in the benzo[a]pyrene 10 microgram/ml + microsomal fraction treated cells among all treated cells. The DPCs were measured in those cells at 12 hour, 24 hour, 48 hour and 72 hour later to monitor the change of the amount of DPCs to see the repair of DPCs. The result showed that the amount of crosslinked DNA were decreased by the time. But considering the cell proliferation, the DPCs amount were not changed much and the repair did not seem to occur well.
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Citations
Citations to this article as recorded by - Enhancement of DNA damage and involvement of reactive oxygen species after exposure to bitumen with UVA irradiation
Yun-Chul Hong, Kwan-Hee Lee
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis.1999; 426(1): 63. CrossRef
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22
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The effect of smoking and alcohol intake on routine laboratory tests in male white collor workers
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Kang Sook Lee, Yun Chul Hong, Chung Yill Park
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Korean Journal of Occupational and Environmental Medicine 1992;4(2):199-211. Published online October 31, 1992
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DOI: https://doi.org/10.35371/kjoem.1992.4.2.199
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Abstract
PDF
- No abstract available.
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Citations
Citations to this article as recorded by - Association of Work-related Characteristics and Hypertension among White Collar Workers
Chae-Bong Kim, KyooSang Kim
Journal of Korean Society of Occupational and Environmental Hygiene.2015; 25(3): 418. CrossRef - Relationship Between Life Style and Serum Lipid Levels in Adults using Data from Health Examination
Su-Jin Oh, Eun-Sook Shin, Young-Chae Cho
Journal of the Korea Academia-Industrial cooperation Society.2014; 15(8): 5009. CrossRef
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22
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Visual display terminal work during pregnancy and the risk ofspontaneous abortion
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Kang Sook Lee, Yun Chul Hong, Chung Yill Park, Kwan Ho Meng
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Korean Journal of Occupational and Environmental Medicine 1991;3(2):209-215. Published online November 30, 1991
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DOI: https://doi.org/10.35371/kjoem.1991.3.2.209
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Abstract
PDF
- No abstract available.
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Citations
Citations to this article as recorded by - The factor affecting job stress and psychosocial well-being of prison officers
Jung-Wan Koo, Hyun-Jung Kim
International Congress Series.2006; 1294: 175. CrossRef
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17
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