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Adipose Tissue and Serum Levels of PCBs and DDE in Women with Gynecologic Benign Disease
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Sung Kyun Park, Kang Sook Lee, Young Man Rho, Jung Wan Koo, Sun Young Min, Jin Goo Han, Won Kyoung Ko, Mi Ran Kim, Jae Keun Chung, Jong Seung Lee, Jin Hong Kim
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Korean Journal of Occupational and Environmental Medicine 2000;12(1):81-92. Published online March 31, 2000
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DOI: https://doi.org/10.35371/kjoem.2000.12.1.81
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Abstract
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- OBJECTIVES
This study was purposed to determine the levels of PCBs and DDE in adipose tissue and serum and to evaluate the relations with factors affecting these levels. METHODS We analyzed adipose tissues and sera from 52 gynecologic benign disease patients aged 27-78 years, except hormonal diseases such as breast cancer and endometriosis. We also surveyed age, education, occupation, body mass index (BMI), smoking, drinking, number of children, and duration of breastfeeding by questionnaires. Tissue and serum levels of PCBs and DDE were measured using gas chromatography. RESULTS The median and geometric mean levels of PCBs were 48. 29 ng/g, 56. 78 ng/g for adipose tissue and 4. 67 uc/L, 4. 85 m/L for serum, and those of DDE were 142.89 ng/g, 117.06 ng/g for adipose tissue and l. 75 m/L, 2.09 ua/L for serum, respectively. Adipose tissue and serum levels for DDE showed high correlation (r=0. 310, p=0. 0002), but those of PCBs didn' t (r=0.029, p=0.2582). In analyses of the differences of the means of log transformed adipose tissue and serum PCBs and DDE levels for groups of potential covariates, only adipose tissue DDE levels were significantly associated with number of children (p=0.015), age at first birth (p=0.014) and BMI (p=0.035). In multiple regression analysis, adipose tissue DDE levels were significantly increased with decreasing number of children and increasing age at first birth. CONCLUSIONS This study suggested that parity and adiposity were associated with levels of DDE in adipose tissue, and adipose tissue is a better biomarker than serum for evaluating the long-term exposure of organochlorines.
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Job Performance of Occupational Health Personnel
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Yun Chul Hong, Eun Hee Ha, Kyung Ja Jun, Young Man Rho, Hye Sook Park, Heui Sug Jo, Hun Jae Lee, Mi Ran Yang
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Korean Journal of Occupational and Environmental Medicine 1997;9(3):496-507. Published online October 31, 1997
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DOI: https://doi.org/10.35371/kjoem.1997.9.3.496
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Abstract
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- No abstract available.
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Citations
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Jung-Ah Yun, Soon-Lae Kim, Hye-Sun Jung Korean Journal of Occupational Health Nursing.2013; 22(2): 159. CrossRef - The Effect of Korean Occupational Health Nurses' Work Conditions on their Performance
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