Annals of Occupational and Environmental Medicine

Seung Jun Wang

2 Articles

The variation of thiodiglycolic acid concentration in urine with vinyl chloride exposure levels in rats: Seung Jun Wang, Bong Suk Cha, Jae Hoon Roh, Dong Chun Shin, Myung Su Kim, Keun Jae Jeon; Korean Journal of Occupational and Environmental Medicine 1999;11(4):431-438. Published online December 31, 1999; DOI: https://doi.org/10.35371/kjoem.1999.11.4.431

Abstract PDF: OBJECTIVES
It is the objective of this research to identify the variation of thiodiglycolic acid (TdGA) in urine with vinyl chloride monomer (VCM) exposure levels through methylation.
METHODS
After rats were exposed to vinyl chloride monomer of 4 levels, 0 mg/m3, 50 mg /m3, 150 mg/m3, 500 mg/m3, respectively, of which urine was sampled in each sampling time of 0 hour, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours, 36 hours, 48 hours. After urine had been methylated with diazomethane in the preliminary experiment and the peak of 146 m/z had been verified, the main experiment was done.
RESULTS
In the variation of TdGA with sampling times, concentration of TdGA increased rapidly in 4 hours and then decreased after 8 hours. When the variation of urinary .TdGA concentration in urine according to exposure level of VCM was verified through Kruskal-Wallis statistical method at each sampling time, the significant increment with the exposure levels at 2 hours, 4 hours, 8 hours after exposure was clarified.
CONCLUSION
TdGA concentration in urine with increment of VCM exposure level increased, especially significantly at 2 hours, 4 hours, 8 hours of sampling time.

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Effect of Economic Depression on Psychosocial Distress of Industrial Workers: Bong Suk Cha, Sang Baek Koh, Seung Jun Wang, Sei Jin Chang; Korean Journal of Occupational and Environmental Medicine 1998;10(4):484-492. Published online December 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.4.484

This study was carried out to assess the effect of economic depression on psychosocial distress, and to assess the relationship between differences of psychosocial distress and job characteristics (job strain), and to find out the effect of social support on psychosocial distress. We measured job characteristics(job demand, job control), and social support(coworker support, supervisor supports) at work by a self-administered questionnaire. Psychosocial distress was measured by PWI(Psychosocial Well-being Index), a 45-item self-administered instrument. Among the 152 respondents, the prevalence of high job strain was 27% (41 persons). The Odds ratio of high job strain was 3.11 (95% CI; 2.12~4.11), and those of passive group and active group were 2.01(95% CI; 0.83~2.76) and 1.80(95% CI; 0.83~2.76), respectively. Our results supported the association between psychosocial distress and job strain. The odds ratio of high strain isolates group (high strain group+low social support) was 3.59 (95% CI; 2.05~5.13), but the odds ratio of high strain collective group was 1.32 (95% CI; 0.23~2.41). Social support at work was modifying factor of the association between psychosocial distress and job strain. Therefore we reviewed the evidence that economic depression was associated with psychosocial distress in this study, and that the strength of the social support was important in maintain health.

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