Annals of Occupational and Environmental Medicine

Nam Won Paik

6 Articles

Effect of Occupational Lead on Male Sex Hormones: Hyeong Su Kim, Soung Hoon Chang, Won Jin Lee, Jae Wook Choi, Jong Tae Park, Nam Won Paik, Rok Ho Kim; Korean Journal of Occupational and Environmental Medicine 2001;13(1):44-54. Published online March 31, 2001; DOI: https://doi.org/10.35371/kjoem.2001.13.1.44

Abstract PDF: OBJECTIVES
This study was performed to evaluate the relationship between biological markers of lead exposure and level of sex hormones in men occupationally exposed to lead.
METHODS
In this study, 33 male workers who employed at smelting and battery factories were compared with 33 male workers who were not exposed to lead. As biological markers of lead exposure, hemoglobin, ZPP, blood lead and urine lead were measured. As sex hormones, FSH, LH, testosterone, SHBG and FTI were determined.
RESULTS
Hemoglobin level was significantly lower in exposed than in nonexposed group. Level of ZPP, blood lead, and urine lead were significantly higher in exposed than in nonexposed group. There was a trend that level of FSH, testosterone, SHBG, and FTI was lower in exposed than in nonexposed group respectively, but there were no statistical significance. In exposed group, FSH level was correlated with age, ZPP, and blood lead; testosterone level was correlated with hemoglobin, blood lead, urine lead, and SHBG; and FTI level was correlated with age.
CONCLUSIONS
Level of some sex hormones were lower in exposed than in nonexposed group but there were no statistical significance between the exposed and the nonexposed group. But level of sex hormones were correlated with several biological markers of lead in exposed group. It suggests that occupational lead exposure might affect sex hormones.

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Prevalence of Asbestosis in Korean Asbestos Industry: Do myung Paek, Nam Won Paik, Jung Deun Choi, Mi A Son, Jung Gi Im, Won Jin Lee, Young Hahn Moon, Jung Sun Park, Byung Soon Choi; Korean Journal of Occupational and Environmental Medicine 1995;7(1):46-57. Published online February 28, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.1.46

Asbestos industry has been in operation over 60 years in Korea. However, the prevalence of asbestosis has not been yet reported. With rapid turn-over of workers, previous cross-sectional studies of current workers on the job could not find cases with exposures long enough for the development of asbestosis. This study was done to evaluate asbestosis prevalence of those worksites with operation history of more than 20 years. In total, 139 workers from 5 worksites were examined. Asbestos industries covered in the study include 2 asbestos textile, 1 brake lining, and 2 ship repairing worksites. Chest x-ray was taken from all workers and read by two exports familiar with pneumoconiosis classification according to 1980 ILO guidelines. Those with findings compatible with asbestosis were further checked with high resolution computerized tomography (HRCT). Pulmonary function tests were done according to ATS guidelines, and occupational and previous medical history was taken through a standardized interview. Air-borne asbestos was measured according to NI0SH method 7400. The air-borno asbestos concentrations ranged from 0.2-1.3 f/cc for asbestos textile, from 0.7~l.0 f/cc for brake lining, and from 6.3-7.8 f/cc during asbestos removal at ship repairing worksite. Of the 139 workers 25 had abnormal chest radiographic findings, and 10 of them had findings compatible with pneumoconiosis. When work history and current asbestos measurements were accounted, 9 workers who had more than 10 years of asbestos exposure history showed chest radiographic findings of pneumoconiosis with Finally, 4 workers showed finding of pulmonary fibrosis and/or pleural thickening at HRCT, and 2 of them had restrictive lung function changes. The study results showed that, among 139 sutjects, there were 4 (3%) definite asbeatosis cases confirmed with HRCT. The prevalence of probable asbestosis was 7% for 10-14 years of exposure, 13% for 15-19 years of exposure, and 23% for 20 or more years of exposure. The prevalence of compensable asbestosis with abnormal lung function was 4-6% for those with 15 or more years of exposure.

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Sustainable management of hazardous asbestos-containing materials: Containment, stabilization and inertization
Shiv Bolan, Leela Kempton, Timothy McCarthy, Hasintha Wijesekara, Udara Piyathilake, Tahereh Jasemizad, Lokesh P. Padhye, Tao Zhang, Jörg Rinklebe, Hailong Wang, M.B. Kirkham, Kadambot H.M. Siddique, Nanthi Bolan
Science of The Total Environment.2023; 881: 163456. CrossRef
Asbestos Exposure Level and the Carcinogenic Risk Due to Corrugated Asbestos-Cement Slate Roofs in Korea
Eun-Soo Lee, Young-Ki Kim
International Journal of Environmental Research and Public Health.2021; 18(13): 6925. CrossRef
Gastric and rectal cancers in workers exposed to asbestos: a case series
Byeong Ju Choi, Saerom Lee, Iu Jin Lee, Soon Woo Park, Sanggil Lee
Annals of Occupational and Environmental Medicine.2020;[Epub] CrossRef
The Asbestos Ban in Korea from a Grassroots Perspective: Why Did It Occur?
Yu-Ryong Yoon, Kyeong Kwak, Yeyong Choi, Kanwoo Youn, Jinwook Bahk, Dong-Mug Kang, Domyung Paek
International Journal of Environmental Research and Public Health.2018; 15(2): 198. CrossRef
A decade of malignant mesothelioma surveillance in Korea
Soon‐Hee Jung, Hyoung‐Ryoul Kim, Sang‐Baek Koh, Suk‐Joong Yong, Myoung Ja Chung, Chang‐Hun Lee, Joungho Han, Min‐Seob Eom, Sung‐Soo Oh
American Journal of Industrial Medicine.2012; 55(10): 869. CrossRef
Comparison of cancer incidence between production and office workers at a shipyard in Korea: A retrospective cohort study from 1992 to 2005
Kyoung‐Sook Jeong, Yangho Kim, Moon‐Chan Kim, Cheol‐In Yoo
American Journal of Industrial Medicine.2011; 54(9): 719. CrossRef
Occupational and Environmental Asbestos Exposure in Korea
Jung-Wan Koo, Hyoung Ryoul Kim
Journal of the Korean Medical Association.2009; 52(5): 442. CrossRef
Overview of Asbestos Issues in Korea
Hyoung Ryoul Kim
Journal of Korean Medical Science.2009; 24(3): 363. CrossRef
Compensation and Diagnosis of Asbestos Related Disease
Soo-Geun Kim
Korean Journal of Family Medicine.2009; 30(5): 335. CrossRef
Asbestos-related Diseases among Asbestos Textile Factory Workers and Residents Around the Factory
Dong-Mug Kang, Dong-Chul Gu, Kun-Hyung Kim
Journal of the Korean Medical Association.2009; 52(5): 482. CrossRef
Asbestos Problems Yet to Explode in Korea
Domyung Paek
International Journal of Occupational and Environmental Health.2003; 9(3): 266. CrossRef
The Effect of Silica Dust on Ventilatory Function of Foundry Workers
Jung Wan Koo, Chee Kyung Chung, Chung Yill Park, Se‐Hoon Lee, Kang‐Sook Lee, Young‐Man Roh, Hyeon Woo Yim
Journal of Occupational Health.2000; 42(5): 251. CrossRef
Asbestos and non-asbestos fiber content in lungs of Korean subjects with no known occupational asbestos exposure history
Je Yu, Young Hahn Moon, Kiyoshi Sakai, Naomi Hisanaga, Jung Duck Park, Yasuhiro Takeuchi
Environment International.1998; 24(3): 293. CrossRef

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A Case Report on Glass Fiber-induced Health Hazard due to Car interior Material: Hyun Sul Lim, Hae Kwan Cheong, Ji Yong Kim, Hoe Kyeong Cheong, Yeol Oh Sung, Nam Won Paik; Korean Journal of Occupational and Environmental Medicine 1994;6(2):439-446. Published online September 30, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.2.439

Abstract PDF: Glass Fiber is manufactured from typical glass-making raw materials, silicon dioxide with various metals and other elements. There are three distinct types of commercial glass fiber products: glass wool, an entangled mass of interlocking fibers; continuous glass filament, a product with a more ordered arrangement of fibers; and special-purpose glass fiber, a small-diameter fiber (less than 3 um) . We report a case of glass fiber-induced health hazard due to continuous glass filament from fiber reinforced plastics (FRF) as car interior material. A 40 years old man complained a sudden onset of severe itching on whole body, especially neck and forearms while driving a new car. He also complained burning of eyes, sore throat and productive cough. We diagnosed the glass fiver-induced skin lesion by placing skin scraping on a slide glass and examining the specimen under a microscope. We found same fibers from the air samples in the car and from the material of the interior surface of the car by the microscopic examination. Therefore we confirmed that the patient's symptoms and signs were induced by glass fiber.

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Development of Technology for Environmental Assessment and Biological Monitoring of Workers Exposed to Benzene: Chul Whan Cha, Kwang Jong Kim, Jung Chul Kim, Nam Won Paik; Korean Journal of Occupational and Environmental Medicine 1994;6(1):122-133. Published online February 28, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.1.122

Abstract PDF

The objective of this study were to evaluate a correlation between airborne benzene concentrations and urinary muconic acid and to evaluate that between airborne benzene concentrations and urinary phenol concentrations. The high performance chromatographic method was used to measure the muconic acid concentrations in urine samples collected from 69 workers exposed to benzene and 155 non-exposed workers. The time weighted average benzene concentrations in breathing zone of workers were also determined. The physical examination and blood counts (hemoglobin, hematocrit, red blood cell, and white blood cell) were made for both workers exposed to benzene and control group. The results are as follows; 1. The geometric mean of airborne benzene concentrations for all workers was 2.0ppm (0.1-56.9ppm). The mean airborne benzene concentration of workers in adhesive tape manufacturing industry was 12.2ppm (8.3-56.9ppm), which was the highest by type of industry. 2. The geometric mean concentration of muconic acid in urine from male workers exposed to benzene was 3.9 mg/l (0.8-40.8 mg/l), which was significantly higher than that of non-exposed workers. The highest muconic acid concentration was indicated in the workers at the adhesive tape manufacturing industry. 3. There was a significant difference between the mean concentration of muconic acid of workers exposed to airborne benzene concentration of 5-10 pm and that of workers exposed to concentrations below 5 ppm. The urinary muconic acid concentration were correlated with airborne benzene concentration for workers (r=0.85). However there was no significant correlation between urinary phenol concentrations and airborne benzene concentrations. 4. The correlation coefficients between the urinary muconic acid concentration and airborne benzene concentration, urinary phenol concentration, exposure dose(airborne benzene concentration x work duration) and white blood cell were 0.85, 0.74, 0.63 and -0.33, respectively.

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Estimating Benzene Exposure Level over Time and by Industry Type through a Review of Literature on Korea
Donguk Park, Sangjun Choi, Kwonchul Ha, Hyejung Jung, Chungsik Yoon, Dong-Hee Koh, Seunghun Ryu, Soogeun Kim, Dongmug Kang, Kyemook Yoo
Safety and Health at Work.2015; 6(3): 174. CrossRef
Occupational Lymphohematopoietic Cancer in Korea
Eun-A Kim, Won Jin Lee, Mia Son, Seong-Kyu Kang
Journal of Korean Medical Science.2010; 25(Suppl): S99. CrossRef
Occupational exposure to benzene in South Korea
Seong-Kyu Kang, Mi-Young Lee, Tae-Kyun Kim, Jeong-Oh Lee, Yeon Soon Ahn
Chemico-Biological Interactions.2005; 153-154: 65. CrossRef

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A Study on the Manganese Exposure and Health Hazards Among Manganese Manufacturing Workers: Ji Yong Kim, Hyun Sul Lim, Hae Kwan Cheong, Nam Won Paik; Korean Journal of Occupational and Environmental Medicine 1994;6(1):98-112. Published online February 28, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.1.98

Abstract PDF

To estimate the manganese (Mn, below) exposure of workers in the ferromanganese manufacture factory and to evaluate its health effects, airborne, blood and urine Mn concentration measurements, questionnaire and other neurologic examinations were performed on 80 Mn-handing productive male workers (exposed group), 47 non-Mn-handling productive male workers (internal control group) and 144 productive male workers in other factory (external control group). The results obtained were as follows; The highest airborne Mn fume concentration among the work process was found at charging (0.42 mg/m3), and ferromanganese crushing process (1.14 mg/m3) was the highest in Mn dust. However all of them were below threshold limit value. Mean Mn concentrations in blood and urine of crushing workers were higher than those of other part workers. Among all of them, workers whose urine Mn concentration were exceed normal reference level (10 microgram/l) were 31 (18.5%). There was statistically significant correlation between airborne and urine Mn concentration (r=0.60), and so between airborne and blood Mn concentration (r=0.49), while there was no statistically significant correlation between blood and urine Mn concentration. Mean Mn concentration in airborne (0.60 mg/m3), urine (6.92 microgram/l) and blood (3.16 microgram/dl) in exposed group were significantly higher than those of control groups (p<0.01). Clinical symptoms such as excessive sweating, hypoesthesia, libido change, anosmia, decreased visual acuity and difficulty in writing showed higher positive rate in exposed group. Positive rate of clinical signs such as eye blinking and masked face in exposed group was higher than external control group. However clinical and laboratory findings such as blood pressure, blood chemistry, grip strength in exposed group were not statistically different from those of control groups. The results suggested that further studies were followed to evaluate the workers whose blood Mn concentration were below normal reference level but urine Mn concentrations above normal reference level, and to establish the questionnaire and the diagnostic tools to detect the Mn poisoning workers early.

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A Study on the Total, Particle Size-Selective Mass Concentration of Airborne Manganese, and Blood Manganese Concentration of Welders in a Shipbuilding Yard
Jong Su Park, Pan Gyi Kim, Jee Yeon Jeong
Journal of Korean Society of Occupational and Environmental Hygiene.2015; 25(4): 472. CrossRef
Neurobehavioral Deficits and Parkinsonism in Occupations with Manganese Exposure: A Review of Methodological Issues in the Epidemiological Literature
Robert M. Park
Safety and Health at Work.2013; 4(3): 123. CrossRef
Exposure-Response Relationship and Risk Assessment for Cognitive Deficits in Early Welding-Induced Manganism
Robert M. Park, Rosemarie M. Bowler, Harry A. Roels
Journal of Occupational & Environmental Medicine.2009; 51(10): 1125. CrossRef
Sequelae of fume exposure in confined space welding: A neurological and neuropsychological case series
Rosemarie M. Bowler, Sanae Nakagawa, Marija Drezgic, Harry A. Roels, Robert M. Park, Emily Diamond, Donna Mergler, Maryse Bouchard, Russell P. Bowler, William Koller
NeuroToxicology.2007; 28(2): 298. CrossRef
State-of-the-Science Review: Does Manganese Exposure During Welding Pose a Neurological Risk?
Annette B. Santamaria, Colleen A. Cushing, James M. Antonini, Brent L. Finley, Fionna S. Mowat
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Issues in neurological risk assessment for occupational exposures: The Bay Bridge welders
Robert M. Park, Rosemarie M. Bowler, Donald E. Eggerth, Emily Diamond, Katie J. Spencer, Donald Smith, Roberto Gwiazda
NeuroToxicology.2006; 27(3): 373. CrossRef

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A Study on Urinary Hippuric Acid and Subjective Symptoms in Toluene Exposed Workers: Joo Ja Kim, Jung O Ham, Kyu Dong Ahn, Byung Kook Lee, Taik Sung Nam, Nam Won Paik; Korean Journal of Occupational and Environmental Medicine 1989;1(2):206-217. Published online November 30, 1989; DOI: https://doi.org/10.35371/kjoem.1989.1.2.206

Abstract PDF

To study the relationship between the urinary hippuric acid and subjective symptoms in toluene exposed workers, urinary hippuric acid was measured and subjective symptoms questionnarire was surveyed in 93 toluene exposed male workers and 96 non-exposed office male workers. The results are as follows: 1. Mean concentration of urinary hippuric acid, which is significantly higher in exposed group than in non-exposed group, was 1.3 g/l, 1.2(GM, GSD respectively) in exposed group and 0.6 g/l, 1.2(GM, GSD respectively) in non-exposed group. 2. Mean concentration of toluene in the air in the workplace, which is significantly higher in the department of coater than in the department of mixing, was 23.4 ppm, 6.2(GM, GSD respectively) in the department of mixing and 59.8 ppm, 3.4(GM, GSD respectively) in the department of coater. 3. Complained rates of subjective symptoms were significantly higher in exposed group than in non exposed group in all items. 4. In exposed group, complained rate of CNS related symptoms was higher than that of irritation related symptoms in the first part but there was no significant difference and complained rate of irritation related symptoms in the second part was significantly higher than that of CNS related symptoms. 5. In exposed group, complained rates of subjective symptoms were not compatible with dose-response relationship by the concentration of urinary hippuric acid, duration of work, department of work, and age group retrospectively.

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A Study of Working Environment for Automotive Painting in Auto Repair Shops and Workers' Exposure to Hazardous Chemicals
Sang-Hyo Sim, Chun-Hwa Jeoung, Jin-Suk Lim, Hyung-Gu Lee, Yoon-Shin Kim
Korean Journal of Environmental Health Sciences.2009; 35(3): 153. CrossRef

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