-
Risk factors including night shift work of colorectal polyp
-
Kanghyun Um, Chung-soo Park, Cheolin Yoo, Yeon-Soon Ahn, Moonchan Kim, Kyoung Sook Jeong
-
Ann Occup Environ Med 2020;32:e26. Published online July 13, 2020
-
DOI: https://doi.org/10.35371/aoem.2020.32.e26
-
-
Abstract
PDFPubReaderePub
- Background
The destruction of circadian rhythms by night shift work affects major circadian genes, which are known to play a role in advancing or killing the cell cycle through tumor suppressor genes. To find out whether night shift work affects the incidence of colorectal cancer, which was found to be associated with long-term night shift work in previous studies, we surveyed effect of night shift work on colorectal polyps that have a higher incidence than colorectal cancer and can progress to colorectal cancer. MethodsTo examine the correlation between rotating night shifts and colorectal polyps, a survey was conducted with 299 men aged 40–60 years from two university hospitals. We examined lifestyle, work history, work patterns, and colonoscopy results. The differences in prevalence among the groups was compared, and prevalence ratio (PR) was calculated via generalized linear modeling. ResultsThe prevalence of colorectal polyps in night shift and non-shift workers were 53.0% and 33.5%, respectively. After adjusting for age, smoking status, dietary habits, family history of colorectal cancer, obesity, job type, night shift work (PR: 1.13, 95% CI: 1.02–1.25) was a risk factor of colorectal polyps. ConclusionsThe risk of colorectal polyps was greater in night shift workers than non-shift workers. Also risk of colorectal polyp was higher in older group. Our study investigated colorectal polyp instead of colorectal cancer and lacks information about types and gene mutations of colorectal polyps. Further study is needed to clarify effect of night shift work on development of colorectal cancer.
-
Citations
Citations to this article as recorded by
- Spatial clustering of colorectal cancer in Malaysia
Sharifah Saffinas Syed Soffian, Azmawati Mohammed Nawi, Rozita Hod, Khairul Nizam Abdul Maulud, Ahmad Tarmizi Mohd Azmi, Mohd Hazrin Hasim Hashim, Huan-Keat Chan, Muhammad Radzi Abu Hassan Geospatial Health.2023;[Epub] CrossRef - Circadian regulation of digestive and metabolic tissues
Zainab Taleb, Phillip Karpowicz American Journal of Physiology-Cell Physiology.2022; 323(2): C306. CrossRef - Do sleep quality and psychological factors link precancerous conditions of colorectal cancer? A retrospective case-control study
Wei Liu, Huijie Zhang Expert Review of Gastroenterology & Hepatology.2022; 16(2): 173. CrossRef - Prevalence of Colorectal Polyps Based on Cardiorespiratory Fitness, Muscle Strength, Health Behavior, and Abdominal Obesity in Asymptomatic Elderly
Shiyu Zhang, Junyong Zhang, Yonghwan Kim, Wangyang Zhang Healthcare.2021; 9(10): 1400. CrossRef - The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation
Kyle Stokes, Malika Nunes, Chantelle Trombley, Danilo E.F. L. Flôres, Gang Wu, Zainab Taleb, Abedalrhman Alkhateeb, Suhrid Banskota, Chris Harris, Oliver P. Love, Waliul I. Khan, Luis Rueda, John B. Hogenesch, Phillip Karpowicz Cellular and Molecular Gastroenterology and Hepatology.2021; 12(5): 1847. CrossRef
-
58
View
-
0
Download
-
5
Web of Science
-
5
Crossref
|