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Lifestyle and Work related Factors Associated with Serum PFOA among Workers at Manufacturing Companies
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Sang Hwan Jang, Chae Kwan Lee, Dae Hwan Kim, Kwon Bok Kim, Jin Hong Ahn, Hwi Dong Kim, Chang Hee Lee, Jeong Ho Kim, Jong Tae Lee
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Korean Journal of Occupational and Environmental Medicine 2008;20(3):233-244. Published online September 30, 2008
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DOI: https://doi.org/10.35371/kjoem.2008.20.3.233
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 Abstract
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- OBJECTIVES
The objective of this study was to determine serum perfluorooctanoic acid (PFOA) concentrations and to investigate the relationship of lifestyle, health status and work-related factors among workers at manufacturing companies with possible occupational exposure to PFOA.
METHODS
The study subjects were 315 workers (male 203, female 112) of manufacturing companies with possible exposure to PFOA from August to December, 2007. A questionnaire was administered to investigate lifestyle and work-related factors. Serum PFOA concentrations were analyzed by LCMS/ MS, and liver function and total cholesterol were also tested.
RESULTS
Serum PFOA concentrations ranged from 1.0 to 40.9 ng/mL (mean 8.0 ng/mL). Serum PFOA concentrations increased with age. Male workers had higher PFOA concentration than female workers (male 9.0 ng/mL; female 6.3 ng/mL). According to stepwise multiple regression analysis, factors significantly associated with PFOA concentration were male, being older, higher total cholesterol, and lower body mass index. Adjusted for age and gender by logistic regression, dyeing and finishing textiles had significantly higher odds ratio (OR) of 6.16, and moulding patterns, moulds and industrial patterns (OR=4.84), sections for ships (OR=3.87), and plastics synthetic leather (OR=10.05) had marginally significantly high odds ratios.
CONCLUSIONS
This study demonstrated the factors affecting serum PFOA concentration of workers at manufacturing companies. Further study is needed to ensure the effect of occupational exposure on serum PFOA concentration.
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Citations
Citations to this article as recorded by  - The relationships between sixteen perfluorinated compound concentrations in blood serum and food, and other parameters, in the general population of South Korea with proportionate stratified sampling method
Hee-Young Kim, Seung-Kyu Kim, Dong-Mug Kang, Yong-Sik Hwang, Jeong-Eun Oh
Science of The Total Environment.2014; 470-471: 1390. CrossRef - Concentration of PFOA and PFOS in Whole Blood and Factors Controlling Their Exposure Among Koreans
Chun-Hui Suh, Chae-Kwan Lee, So-Ryong Lee, Mi-Hee Park, Jong-Tae Lee, Byung-Chul Son, Jeong-Ho Kim, Kun-Hyung Kim
Korean Journal of Environmental Health Sciences.2012; 38(2): 105. CrossRef
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