Annals of Occupational and Environmental Medicine

Jung Hak Kang

2 Articles

Impact of Solvent Exposure on the Occupational Hearing Loss: Ji Ho Lee, Young Ju Go, Hun Lee, Jung Hak Kang, Cheol In Yoo, Choong Ryeol Lee, Yang Ho Kim; Korean Journal of Occupational and Environmental Medicine 2000;12(4):537-546. Published online December 31, 2000; DOI: https://doi.org/10.35371/kjoem.2000.12.4.537

OBJECTIVES
This study was to evaluate the impacts of simultaneous exposure to noise and mixed solvents on workers'hearing threshold level (HTL) over five-year period.
METHODS
The study was conducted by interview and annual audiometric test on workers in ship building industry from 1994 to 1998. The cases(workers who exposed to noise and mixed solvent simultaneously) were 43 male workers and controls (workers who exposed to nolle) were selected by matching method with regard to age, sex, carrier, and noise exposure level. To assess the impacts of solvent exposure on hearing threshold level, with considering other factors, general liner model was used.
RESULTS
1. The audiogram of all subjects showed typical sensorineural hearing loss pattern. The mean HTLe were increased at high frequency (4000HB and 8000Hz) for study period. 2. The HTLs of cases were more increased than those of controls at high frequencies (4000Hz and 8000Hz), but there was not statlstical significance. 3. The impact of age on the HTL was statistically significant at 250Hz and 500Hz (p(0.05), and the impact of noise on the HTL was statistically significant at 250Hz, 2000Hz and 4000Hz (p(0.05), but the impact solvent exposure on the HTL was not significant. 4. The changes in HTLs of cases were higher than those of controls at high frequency, there were not statistical significance at 4000Hz, but only at 8000Hz (p=0.087). 5. Statistical analysis of the general linear model implicated that the changes in HTL was impacted by noise exposure bevel significantly (p=0.031) and Impacted by solvent exposure weakly (p=0.087) at 8000Hz.
CONCLUSIONS
The results of this study suggest that workers who simultaneously exposed to noise and mixed solvent were at risk for more affected HTL than those exposed to noise exposure only, but we could not find definitive evidence. Further detailed studies must be made in large number of workers.

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Occupational Hearing Loss in Korea
Kyoo Sang Kim
Journal of Korean Medical Science.2010; 25(Suppl): S62. CrossRef

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Neuroendocrine Effects in Occupational Solvents Exposure: Chae Un Lee, Jong Tae Lee, Ui Wha Chung, Hae Suk Sohn, Deog Hwan Moon, Jin Ho Chun, Jung Hak Kang, Chang Hee Lee, Hwi Dong Kim, Jong Ham Kim, Kui Oak Jung; Korean Journal of Occupational and Environmental Medicine 1995;7(2):362-374. Published online October 31, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.2.362

Abstract PDF

Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic solvents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls (33men, 85women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone (FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone (GH), and thyroid-stimulating hormone (TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones (FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.

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Risk Assessment for Non-Cancer Effects of Volatile Organic Compounds in Children's Products
Jungkon Kim, Jung-Kwan Seo, Taksoo Kim, Gun-Ho Park
Korean Journal of Environmental Health Sciences.2014; 40(3): 178. CrossRef

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