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The association between shift work and hyperuricemia in steelmaking male workers
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Jae-Seok Oh, Won-Jun Choi, Min-Kee Lee, Sung-Woo Han, Seung-Ho Song, Jong-Wan Yun, Sang-Hwan Han
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Ann Occup Environ Med 2014;26:42. Published online November 4, 2014
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DOI: https://doi.org/10.1186/s40557-014-0042-z
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Abstract
PDFPubReaderePub
- Objectives
The aim of this study was to examine the association between shift work and hyperuricemia among steel company workers. MethodsWe examined 1,029 male workers at a Korean steel company between June 6 and June 28, 2013. We conducted anthropometric measurements, questionnaire surveys, and blood tests. Hyperuricemia was defined as a serum uric acid concentration of ≥7.0 mg/dL. Logistic regression analyses were performed. In the full model, analysis was adjusted for covariates including age, body mass index, lifestyle factors, and comorbidities. The odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for all models. ResultsThe participants included 276 daytime workers and 753 shift workers. Among daytime workers, 72 (26.1%) individuals had hyperuricemia, as did 282 (37.5%) individuals among shift workers (p <0.001). There was a statistically significant association between shift work and hyperuricemia. In the unadjusted model, the OR of shift work was 1.70 (95% CI 1.25-2.31) for hyperuricemia. In the full model, the OR of shift work was also statistically significant after adjustment for covariates (OR 1.41, 95% CI 1.02-1.96). ConclusionsAmong male steel workers, a significant association between shift work and hyperuricemia was observed.
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Citations
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- Influence of occupational exposure on hyperuricemia in steelworkers: a nested case–control study
Yuanyu Chen, Yongzhong Yang, Ziwei Zheng, Hui Wang, Xuelin Wang, Zhikang Si, Rui Meng, Guoli Wang, Jianhui Wu BMC Public Health.2022;[Epub] CrossRef - Serum uric acid concentration is associated with hyperhomocysteinemia in hypertensive Chinese adults
Wen Wang, Qian Wang, Nan Yang Blood Pressure Monitoring.2022; 27(3): 147. CrossRef - An association of smoking with serum urate and gout: A health paradox
Niamh Fanning, Tony R. Merriman, Nicola Dalbeth, Lisa K. Stamp Seminars in Arthritis and Rheumatism.2018; 47(6): 825. CrossRef
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The Relevance of Hyperuricemia and Metabolic Syndrome and the Effect of Blood Lead Level on Uric Acid Concentration in Steelmaking Workers
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Deul Lee, Won-Jun Choi, Jae-Seok Oh, Min-Kee Yi, Sung-Woo Han, Jong-Wan Yun, Sang-Hwan Han
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Ann Occup Environ Med 2013;25:27-27. Published online October 25, 2013
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DOI: https://doi.org/10.1186/2052-4374-25-27
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Abstract
PDFPubReaderePub
- Objectives
Uric acid concentration is known to increase the prevalence of metabolic syndrome by affecting its components, resulting in increased risk of cerebrovascular and cardiovascular diseases, and long-term lead exposure is known to affect this serum uric acid level. In this study, we aimed to examine the association between the causes of hyperuricemia and metabolic syndrome, and to determine whether an increased blood lead level affects hyperuricemia. MethodAnthropometric measurements, surveys, and blood tests were conducted between May and June 2012 in 759 men working in the steelmaking process at a domestic steel company. Workers were divided into 2 groups according to the presence or absence of hyperuricemia, and an analysis was performed to examine its association with metabolic syndrome. In addition, the workers were divided into 3 groups according to the blood lead level to analyze the association between blood lead and hyperuricemia. ResultsThe geometric mean (standard deviation) of the blood lead levels in the hyperuricemia group was significantly higher than that of the healthy group (3.8 [1.8] vs. 3.3 [1.8] μg/dL). The adjusted odds ratio for metabolic syndrome of the hyperuricemia group increased significantly to 1.787 (1.125–2.839) compared with the healthy group. In addition, the adjusted odds ratios for the occurrence of hyperuricemia in the tertile 2 (2.61–4.50 μg/dL) and tertile 3 groups (>4.50 μg/dL) according to blood lead level significantly increased to 1.763 (1.116–2.784) and 1.982 (1.254–3.132), respectively, compared with the tertile 1 group (< 2.61 μg/dL). ConclusionHyperuricemia is believed to function as an independent risk factor for metabolic syndrome, while lead seems to increase the serum uric acid level even at a considerably low blood level. Therefore, attention should be given to patients with hyperuricemia and metabolic syndrome who are prone to lead exposure, and a prospective study should be conducted to identify their causal relationship.
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Citations
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Zheng-Dong Wu, Xiao-Ke Yang, Yi-Sheng He, Jing Ni, Jie Wang, Kang-Jia Yin, Ji-Xiang Huang, Yue Chen, Ya-Ting Feng, Peng Wang, Hai-Feng Pan Environmental Research.2022; 212: 113377. CrossRef - Association of hyperuricemia and metabolic syndrome in type 2 diabetes mellitus patients in Dakar
Oumou Kesso Barry Nènè, Djite Moustapha, Matar Kandji Pape, Hadji Malick Ndour El, Assane Ndour Michel, Diedhiou Demba, Fatou Gueye-Tall, Palanga Koboyo Alix, Marieme Thioune Ndeye, Fatou Coly Najah, Doupa Dominique, Ndour Mbaye Maimouna, Cisse Aynina, Am African Journal of Biochemistry Research.2021; 15(3): 43. CrossRef - Frequency of daily tooth brushing and subsequent cardiovascular events
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Wonkil Jung, Yunkyung Kim, Hoseob Lihm, Jihun Kang International Journal of Rheumatic Diseases.2019; 22(8): 1435. CrossRef - The role of cadmium in obesity and diabetes
Alexey A. Tinkov, Tommaso Filippini, Olga P. Ajsuvakova, Jan Aaseth, Yordanka G. Gluhcheva, Juliana M. Ivanova, Geir Bjørklund, Margarita G. Skalnaya, Eugenia R. Gatiatulina, Elizaveta V. Popova, Olga N. Nemereshina, Marco Vinceti, Anatoly V. Skalny Science of The Total Environment.2017; 601-602: 741. CrossRef
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