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Lung Function in Workers at Small Foundries
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Se Yeong Kim, Jung Il Kim, Ji Hyeon Jung, Suk Hwan Choi, Kap Yeol Jung
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Korean Journal of Occupational and Environmental Medicine 2011;23(3):317-323. Published online September 30, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.3.317
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 Abstract
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- OBJECTIVES
This study investigated lung function in workers exposed to dusts, fumes and noxious gases at small foundries.
METHODS
Lung function was measured in 148 male workers from 12 small foundries and 202 unexposed male workers. Pulmonary function tests performed included: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), percent of FEV1/FVC (FEV1/FVC%), maximum mid-expiratory flow (MMEF), peak expiratory flow (PEF), and forced expiratory flow at 25, 50, and 75% of expired FVC (FEF25, 50, 75).
RESULTS
Mean values of all ventilatory indices except FEF25 of foundry workers were significantly lower than those of controls. Specifically, following stratification by smoking habits, all ventilatory indices except FEF25 of foundry workers were significantly lower than those of controls who smoked; however, there were no significant differences observed in any ventilatory indices between nonsmoking exposed workers and controls. The results of multiple linear regression analysis indicated work duration as a significant predictor of a decrease in FVC%.
CONCLUSIONS
This research indicates that combined occupational exposure to dust, fumes, and gases in small foundries is associated with a reduction in lung function. Smoking may also contribute to respiratory abnormalities. These results suggested that foundry workers should be required to undergo periodic lung function tests and-in addition to not smoking, efficient use of personal protection equipment while at work is recommended.
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Citations
Citations to this article as recorded by  - Cause-Specific Mortality Due to Malignant and Non-Malignant Disease in Korean Foundry Workers
Jin-Ha Yoon, Yeon-Soon Ahn, Suminori Akiba
PLoS ONE.2014; 9(2): e88264. CrossRef - Pulmonary function decline in firefighters and non-firefighters in South Korea
Ju-Hwan Choi, Jae-Hong Shin, Mi-Young Lee, In-Sung Chung
Annals of Occupational and Environmental Medicine.2014;[Epub] CrossRef
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The Brain Pathology on Recovery of Brain MRI after Manganese Administration in Rats
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Ji Hyeon Jung, Jung Il Kim, Se Young Kim, Min Ho Jung, Soon Sub Choi, Soo Jin Kim, Young Jin Park, Kap Yeol Jung
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Korean Journal of Occupational and Environmental Medicine 2010;22(4):371-377. Published online December 31, 2010
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DOI: https://doi.org/10.35371/kjoem.2010.22.4.371
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Abstract
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- OBJECTIVES
This study was carried out to investigate the effect on manganese on the brain of Sprague-Dawley rats, with particular focus on changes to anatomical pathology when brain MRI was recovered after manganese administration.
METHODS
There were 15 rats divided into 3 groups of 5 based on dose of manganese: control group, low dose group (10 mg/kg), and high dose group (40 mg/kg). Each dosing group received an injection of normal saline and manganese via the tail vein once a week for 4 weeks. And then, the rats were observed for 12 weeks after stopping manganese administration. Next, each rat underwent a brain MRI and then each was sacrificed. After the rats were killed, the concentrations of blood manganese were measured, and pathologic examinations of the brain were performed.
RESULTS
The signal intensity of basal ganglia on T1-weighted imaging of brain MRI did not differ between dosing groups. However, the ratio of neuron/glial cell in the basal ganglia was decreased in the low- and high-dose groups compared to the control group.
CONCLUSIONS
This study showed that the damage of neuron in basal ganglia might be permanent after signal intensity of basal ganglia on T1-weighted imaging of brain MRI was recovered.
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