Annals of Occupational and Environmental Medicine

Hyun Soo Kim

6 Articles

Two Case of Erythroleukemia and Myelodysplastic Syndrome in a Non-Destructive Inspector: Myoung Soon Oh, Jae Kook Yoon, Hyun Soo Kim, Hawk Kim, Jin Kyung Lee, Ji Ho Lee, Yang Ho Kim; Korean Journal of Occupational and Environmental Medicine 2011;23(4):471-479. Published online December 31, 2011; DOI: https://doi.org/10.35371/kjoem.2011.23.4.471

BACKGROUND
Ionizing radiation is a group 1 carcinogen according to the IARC(International Agency for Research on Cancer) classification. With the development of the radiation related industry, the number of radiation exposed workers has been increasing. There have been several reports on AML(Acute Myeloid Leukemia) on exposure to ionizing radiation; however, there are no reports of occupational malignant lymphohematopoietic disease related to non-destructive inspection.
CASE
REPORT 1: A 35-years-old male, who had worked for 10 years in non-destructive inspection, was diagnosed with myelodysplastic syndrome. He worked 8 hours a day, for three weeks per months, where he was exposed to 192Ir and 60Co radiation sources. Because he had not worn a film badge for monitoring his radiation exposure dose, the accurate exposure dose was not reported. The estimate exposure dose calculated via a chromosomal study was 1.20 Gy, which exceed the dose limits of Korean radiation dose standards, which are 50 and 100 mSv annually and quinquennially respectively.
CASE
REPORT 2: A 26-years-old male, who had worked for 2.5 years in the same company was also diagnosed with myelodysplastic syndrome.
CONCLUSION
Non-destructive inspection is the main source of ionizing radiation in the workplace, which could be the cause of malignant lymphohematopoietic diseases. Therefore, more practical plans and guidelines are needed to prevent non-destructive inspectors from workplace radiation exposure.

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Assessment of working environment and personal dosimeter-wearing compliance of industrial radiographers based on chromosome aberration frequencies
Younghyun Lee, Songwon Seo, Young Woo Jin, Seongjae Jang
Journal of Radiological Protection.2020; 40(1): 151. CrossRef
Probability of causation for occupational cancer after exposure to ionizing radiation
Eun-A Kim, Eujin Lee, Seong-Kyu Kang, Meeseon Jeong
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Acute radiation syndrome in a non-destructive testing worker: a case report
Ji-Sung Ahn, Jai-Dong Moon, Wonyang Kang, Hyeong-Min Lim, Seunghyeon Cho, Dae-Young Lim, Won-Ju Park
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Consecutive results of blood cell count and retrospective biodosimetry: useful tools of health protection regulation for radiation workers
Seongjae Jang, Jin Kyung Lee, Minsu Cho, Su San Yang, Seung Hyun Kim, Wan Tae Kim
Occupational and Environmental Medicine.2016; 73(10): 694. CrossRef
Retrospective biodosimetry using translocation frequency in a stable cell of occupationally exposed to ionizing radiation
Min Su Cho, Jin Kyung Lee, Keum Seok Bae, Eun-Ae Han, Seong Jae Jang, Wi-Ho Ha, Seung-Sook Lee, Joan Francesc Barquinero, Wan Tae Kim
Journal of Radiation Research.2015; 56(4): 709. CrossRef
Exposure Assessment and Management of Ionizing Radiation
Eun-Kyo Chung, Kab-Bae Kim, Se-Wook Song
Journal of Korean Society of Occupational and Environmental Hygiene.2015; 25(1): 27. CrossRef
Physical Agents and Occupational Disease Compensation: Noise, Vibration, Radiation, and Other Physical Agents
Jiho Lee, Jungwon Kim
Journal of Korean Medical Science.2014; 29(Suppl): S72. CrossRef

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Seroprevalence of Hepatitis A in a Manufacture Workplace: Hyun Soo Kim, Chang Sun Sim, Jae Kook Yoon, Hun Lee, Cheol In Yoo; Korean Journal of Occupational and Environmental Medicine 2010;22(4):356-363. Published online December 31, 2010; DOI: https://doi.org/10.35371/kjoem.2010.22.4.356

Abstract PDF

OBJECTIVES
The prevalence of hepatitis A decreases with improved hygiene and changing lifestyle. However, hepatitis A remains a global problem causing sporadic food-borne infections. Over the past 5 years, hepatitis A incidence has increased, and 15 deaths were reported in 2009 in Korea. Concerns about hepatitis A infection have increased. We checked hepatitis A virus antibody (HAV anti-IgG) in a large manufacturing company, so that the results could be a guideline for workplace preventive plan and health policy for hepatitis A.
METHODS
We investigated the seroprevalence of HAV anti-IgG and the demographic characteristics of employee volunteer, in a company in Ulsan. In addition, we estimated those factors that affected seroprevalence of HAV anti-IgG.
RESULTS
A total of 2,719 employee volunteers were enrolled into the study. The seropositive rate of HAV anti-IgG was 69.8% (n=1,899) and, the seronegative rate was 30.2% (n=820). There were no enrolled employees under age 24 years who tested positive for HAV anti-IgG; in this group, the seropositive rate was 0.0% (n=0); in 25~29 years the rate was 3.9% (n=12) and 26.5% (n=118) in 30~34 years olds. In the 35-39 ears, 61.1% (n=203) tested HAV anti-IgG positive and 86.8% (n=256) of 40~44 years tested positive. Other group tested as follows: 96.5% (n=335) in 45~49 year olds, 98.7% (n=593) in 50~54 year olds, and 100% (n=382) in over 55 years. There was a significantly increasing tendency to test HAV anti-IgG positive according to age group. In the 34-35 year olds, the seropositive rate exceeded the seronegative rate.
CONCLUSIONS
HAV anti-IgG seropositive rate increased according to age. The result can used for guideline recommendationsand establishing hepatitis A policies.

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Seroprevalence of measles, mumps, rubella, and varicella-zoster antibodies in new female nurses in the Republic of Korea
Yeongjae Yoo, Won-Ju Park, Seunghyeon Cho, Dae-Young Lim, Suwhan Kim, Wonyang Kang, Hyeonjun Kim, Jai-Dong Moon
Annals of Occupational and Environmental Medicine.2021;[Epub] CrossRef

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Urinary Excretion of Thiodiglycolic Acid According to Sampling Time in Workers Exposed to Vinyl Chloride Monomer: Hyun Soo Kim, Chi Nyon Kim, Jong Uk Won, Bong Suk Cha, Kyung Jong Lee, Jaehoon Roh; Korean Journal of Occupational and Environmental Medicine 2006;18(2):138-145. Published online June 30, 2006; DOI: https://doi.org/10.35371/kjoem.2006.18.2.138

Abstract PDF

OBJECTIVES
The study was performed to investigate the changes of urinary thiodiglycolic acid (TDGA) concentration in workers exposed to vinyl chloride monomer (VCM) according to the time of sampling urine.
METHODS
The personal exposure to airborne VCM was assessed and urinary TDGA concentration was sampled in 31 workers employed in a VCM and polyvinyl chloride (PVC) manufacturing factory. Urinary TDGA was sampled three times: before the start of the shift after 3 days off (TDGA1), after the end of the first-day shift (TDGA2) and before starting the following day shift after completing the oneday shift (TDGA3). Urinary TDGA in 30 workers who had not been exposed to airborne VCM was sampled after the end of the shift. A gas chromatography/pulsed flame photometric detector (GC/PFPD) was utilized to analyze TDGA concentration in urine after the urine was methylated with trimethylsilyldiazomethane(2.0M in diethyl ether).
RESULTS
The creatinine level was 0.179+/-0.271 mg/g in the control workers and 0.218+/-0.443 mg/g in the workers before the start of the shift after 3 days off (TDGA1), showing no significant difference (p=0.7035). Urine samples were compared according to sampling time in order to investigate the change of urinary TDGA concentration in the case of continuous exposure to airborne VCM. In VCM-exposed workers, urinary creatinine concentration was 0.434+/-0.623 mg/g in TDGA2 and 0.767+/-1.056 mg/g in TDGA3, which indicated a gradual but significant increase (p=0.024). In terms of the statistical correlation between airborne VCM and urinary TDGA to evaluate exposure dose per day, of the three urinary TDGA concentrations, TDGA3 showed the highest degree of regression (R(2)=0.4215) with 8h-TWA airborne VCM concentration.
CONCLUSION
Based on this result, the excretion half-life of urinary TDGA was assumed to be less than 3 days, because the concentration of urinary TDGA at 3 days after exposure to airborne VCM was decreased to the level of urinary TDGA concentration in the control workers. The concentration of urinary TDGA increased in the case of continuous shift, due to the accumulation of residual metabolites of TDGA. It was considered that TDGA3 can be applied as a useful biological index to evaluate the exposure dose of airborne VCM during one day because TDGA3 showed the highest correlation with the exposure dose of airborne VCM in the previous shift day.

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Assessment of urinary thiodiglycolic acid exposure in school-aged children in the vicinity of a petrochemical complex in central Taiwan
Po-Chin Huang, Li-Hsuan Liu, Ruei-Hao Shie, Chih-Hsin Tsai, Wei-Yen Liang, Chih-Wen Wang, Cheng-Hsien Tsai, Hung-Che Chiang, Chang-Chuan Chan
Environmental Research.2016; 150: 566. CrossRef

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Prevalence of Occupational Asthma in TDI-Exposed Workers: Hyoung Ryoul Kim, Cheol Woo Kim, Yun Chul Hong, Hyung Joon Chun, Chi Nyon Kim, Hyun Soo Kim, Jee Na Lee, Joo Yeon Shin, Dong Hee Koh, Jaehoon Roh; Korean Journal of Occupational and Environmental Medicine 2004;16(2):191-199. Published online June 30, 2004; DOI: https://doi.org/10.35371/kjoem.2004.16.2.191

Abstract PDF: OBJECTIVES
This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers.
METHODS
We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests.
RESULTS
Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma, and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1%). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test.
CONCLUSIONS
The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.

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Pain Related Factors in Upper Extremities Among Hospital Workers Using Video Display Terminals: Hyoung Ryoul Kim, Jong Uk Won, Jae Suk Song, Chi Nyon Kim, Hyun Soo Kim, Jaehoon Roh; Korean Journal of Occupational and Environmental Medicine 2003;15(2):140-149. Published online June 30, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.2.140

Abstract PDF

OBJECTIVES
This study was designed to quantify symptoms in the upper extremities and to identify the pain related factors among hospital workers using video display terminals.
METHODS
The subject-group consisted of 138 employees working at a hospital using video display terminals. A structured questionnaire was used to estimate the participants' general characteristics, and job contents. Job stress was measured using Karaseks JCQ(Job Content Questionnaire). Pain in the upper extremities was identified according to the NIOSH symptoms survey criteria. Quantification was measured using Kim Chul's method. Pearson's Correlation analysis was used to identify validity in quantification. VAS(visual analog scale) was used to compare with this method. Multiple regression analyses elucidated the relationship between quantified pain and various work factors, such as job stress. Data were analysed with SAS 6.12 program.
RESULTS
First, in quantification using Kim Chul's method, the correlation between modified PRS(pain rating score) and VAS was extremely high by 0.60(P<0.01), indicating the high validity of PRS. Second, the groups of high job demand, high job control, and females were related to an increased pain level.
CONCLUSIONS
These results suggest that the self pain assessment method, PRS, is valuable and useful in analyzing occupational musculoskeletal symptoms. High demand, job control and gender may influence the levels of pain. Prospective studies about musculoskeletal disorder are required.

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The association between long working hours and work-related musculoskeletal symptoms of Korean wage workers: data from the fourth Korean working conditions survey (a cross-sectional study)
Jae-Gwang Lee, Guang Hwi Kim, Sung Won Jung, Sang Woo Kim, June-Hee Lee, Kyung-Jae Lee
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
A study on relationships between characteristics of smart usage and symptoms of MSDs
Kyung-In Kim, Seo-Yeon Choi, Dong-Hyun Park
Journal of the Korea Safety Management and Science.2016; 18(1): 119. CrossRef
Change in Musculoskeletal Pain in Patients With Work-Related Musculoskeletal Disorder After Tailored Rehabilitation Education: A One-Year Follow-Up Survey
Dong Hun Lee, Boram Kang, Seungyoung Choi, Taikon Kim, Seong Ho Jang, Kyu Hoon Lee, Mi Jung Kim, Si-Bog Park, Seung Hoon Han
Annals of Rehabilitation Medicine.2015; 39(5): 726. CrossRef
Related Factors to Musculoskeletal Discomfort Symptoms on Some Middle·High school Teachers
Jae-Yoon Lee, Byeong-Yeon Moon, Youn-Hong Jeong, Hyun-Kyung Woo
Journal of the Korea Academia-Industrial cooperation Society.2012; 13(1): 264. CrossRef
Effect on Turnover Intention in Hotel Employees with Musculoskeletal Pains by Working Environment
Seong-Yeol Kim
The Journal of the Korea Contents Association.2012; 12(8): 256. CrossRef
Work-related Musculoskeletal Diseases and Occupational Injuries in Health Care Workers
Jung-Yeon Hong, Jung-Wan Koo
Journal of the Korean Medical Association.2010; 53(6): 446. CrossRef
Gender-related Factors Associated with Upper Extremity Function in Workers
Kyoo Sang Kim, Min Gi Kim
Safety and Health at Work.2010; 1(2): 158. CrossRef

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Benzidine Exposure Among Benzidine-based Dye Manufacturing Workers: Jae Hoon Roh, Yeon Soon Ahn, Kyoo Sang Kim, Chi Nyon Kim, Hyun Soo Kim; Korean Journal of Occupational and Environmental Medicine 1995;7(2):347-353. Published online October 31, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.2.347

Abstract PDF

To evaluate,the differences of benzidine exposure patterns of the workers in two benzidine-based dye manufacturing factories, the concentration of benzidine: in. air, blood, and urine were measured. The air levels of benzidine dihydrochloride and benzidine-based dye were measured by high performance liquid chromatography with ultraviolet detector. Blood samples were collected at 3 hours after exposure and urine samples were collected at the end of shift. Blood and urine samples were analyzed by high performance liquid chromatography with electrochemical detector. The level of benzidine in reaction process (input, diazotization, and coupling); was 0.381+/-7950 g/m3. The blood benzidine was deteced in 25 workers among 38 in reaction process and their mean levels were 0.0153?0376 ng/mg Hb. The urinary benzidine was detected for 11 workers among 38 workers in the reaction process. The level of benzidine-based dye in drying and packing process was 52.1748+/-4.4111g/m3. The blood benzidine was deteced in 6 workers among 38 in drying and packing process and their mean levels was 0.0062+/-0274 ng/mg Hb. The urinary benzidine was detected for 1 worker among 38 workers exposed to benzidine-based dye. The blood and urinary benzidine were detected in workers exposed to benzidine-based dye. Such results suggested that some part of benzidine-based dye was metaboized to benzidine. Therefore, some regulations for manufacturing and use of the benzidine-based dye are needed to prevent its hazards in industries.

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A work-relatedness assessment in epidemiological case investigation of occupational cancers: II. Practice: an upper urinary tract cancer in a dyer
Kihun Kim, Hyeoncheol Oh, Jungwon Kim
Annals of Occupational and Environmental Medicine.2020;[Epub] CrossRef

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