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A Study on the Change of the Bone Density among Workers Exposed to Hydrofluoric Acid
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Ji Yong Kim, Hyun Sul Lim, Hoe Kyeong Cheong, Hyeon Kyeong Lee, Heung Sik Kang
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Korean Journal of Occupational and Environmental Medicine 1995;7(1):120-127. Published online February 28, 1995
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DOI: https://doi.org/10.35371/kjoem.1995.7.1.120
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 Abstract
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- Hydrofluoric acid is one of the strongest irritating, corrosive and poisonous inorganic chemicals. The most significant chronic consequence of excessive fluoride exposure is the disorder of skeletal system and connective tissue. The first stage of osteofluorosis consists of an increase in the density of flatbone such as pelvic bone and vertebral bones, with coarseness and blurring of bone trabecular. Therefore we wanted to observe the change of the bone density among workers exposed to hydrofluoric acid. Questionnaires and radiological investigations were performed for 39 hydrofluoric acid manufacturing factory worker sexposed to hydrofluoric acid. And then authors checked urinary fluoride level by fluoride ion method. the radiographs were doubly read by two radiologists for reliability.
The results were as follows; 1. There was a significant difference in urinary fluoride level (p<0.01), but not in age, in tenure(p>0.05) among workers by the job title.
2. By the two radiologists, eight cases were read as bone fluorosis. The prevalence rate of bone fluorosis was 20.5%.
3. There was not a significant difference in general characteristic such as age, tenure and in muculoskeletal signs and symptoms between the fluorosis group and the normal group.
4. However, a close relationship between the occurence of the change of bone density and the degree of fluorde exposure such as burn was found.
The difficulties in diagnosing fluorosis result from the questionable sensitively of x-ray techniques and from the non-specific associated signs and symptoms. A quantitative method such as densitometry to assessosteosclerosis and bone structure alteration and a follow-up study are needed.
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Citations
Citations to this article as recorded by  - Health Care Plan for Hydrogen Fluoride Spill, Gumi, Korea
Hyun-Sul Lim, Kwan Lee
Journal of Korean Medical Science.2012; 27(11): 1283. CrossRef
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A Case Report on Glass Fiber-induced Health Hazard due to Car interior Material
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Hyun Sul Lim, Hae Kwan Cheong, Ji Yong Kim, Hoe Kyeong Cheong, Yeol Oh Sung, Nam Won Paik
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Korean Journal of Occupational and Environmental Medicine 1994;6(2):439-446. Published online September 30, 1994
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DOI: https://doi.org/10.35371/kjoem.1994.6.2.439
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Abstract
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- Glass Fiber is manufactured from typical glass-making raw materials, silicon dioxide with various metals and other elements. There are three distinct types of commercial glass fiber products: glass wool, an entangled mass of interlocking fibers; continuous glass filament, a product with a more ordered arrangement of fibers; and special-purpose glass fiber, a small-diameter fiber (less than 3 um) .
We report a case of glass fiber-induced health hazard due to continuous glass filament from fiber reinforced plastics (FRF) as car interior material. A 40 years old man complained a sudden onset of severe itching on whole body, especially neck and forearms while driving a new car. He also complained burning of eyes, sore throat and productive cough.
We diagnosed the glass fiver-induced skin lesion by placing skin scraping on a slide glass and examining the specimen under a microscope. We found same fibers from the air samples in the car and from the material of the interior surface of the car by the microscopic examination. Therefore we confirmed that the patient's symptoms and signs were induced by glass fiber.
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