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Association between Job Stress and the Minnesota Multiphasic Personality Inventory in Firefighters
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Dong Hyul Lee, Hyun Jun Jeon, Dong Hoon Shin, In Sung Chung, Mi Young Lee
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Korean Journal of Occupational and Environmental Medicine 2009;21(4):324-336. Published online December 31, 2009
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DOI: https://doi.org/10.35371/kjoem.2009.21.4.324
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 Abstract
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- OBJECTIVE: To investigate the relationship of job stress and scores on the Minnesota Multiphasic Personality Inventory (MMPI) clinical scales in firefighters.
METHOD
A total of 648 firefighters from Daegu Metropolitan City were given 2 sets of questionnaires, the Korean Occupational Stress Scales (KOSS) and the MMPI. The results of 428 qualifying questionnaires were analyzed using ANOVA, correlation, and multiple regression.
RESULTS
The study demonstrated that job stress differed by age, department, amount of exercise, and duty period. MMPI clinical scales differed by age, smoking, and amount of exercise. Job stress correlated with MMPI clinical scales and in particular with 2 MMPI clinical scales, -Depression and Social introversion-. In addition, job stress subscales were related. On multiple regression analysis, some MMPI clinical scales were affected by job stress subscales.
CONCLUSION
This study suggests that job stress is associated with psychogenic factors in firefighters. The effective management for job stress might be helpful for the overall mental health of firefighters. Further study is required to determine which psychogenic factors are related to job stress.
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Citations
Citations to this article as recorded by  - Do police officers and firefighters have a higher risk of disease than other public officers? A 13-year nationwide cohort study in South Korea
Minkyung Han, Sohee Park, Jong Heon Park, Seung-sik Hwang, Inah Kim
BMJ Open.2018; 8(1): e019987. CrossRef - Particularities of occupational health and safety management in the police environment
Adrian-Constantin Achim
Proceedings of the International Conference on Business Excellence.2018; 12(1): 1. CrossRef - Minnesota multiphasic personality inventory as related factor for post traumatic stress disorder symptoms according to job stress level in experienced firefighters: 5–year study
In-Sung Chung, Mi-Young Lee, Sung-Won Jung, Chang-Wook Nam
Annals of Occupational and Environmental Medicine.2015;[Epub] CrossRef - Relationship between Occupational Stress and Work-related Musculoskeletal Disorders in Korean Male Firefighters
Min Gi Kim, Kyoo-Sang Kim, Jae-Hong Ryoo, Seung-Won Yoo
Annals of Occupational and Environmental Medicine.2013;[Epub] CrossRef - Influence of Job Stress and State of Sleep on the Depression of Emergency Medical Technicians
Chun Yee Lee, Eun Kyung Byun, Nam Hee Kim
Korean Journal of Occupational Health Nursing.2013; 22(3): 191. CrossRef - Duty-Dependent Changes in Stress Hormones of Firefighters
Kyoo-Sang Kim, Seung-Won Yoo, Yong-Lim Won, Mi-Young Lee
Korean Journal of Environmental Health Sciences.2012; 38(3): 195. CrossRef - Health Hazards in Firefighters
Kyoo Sang Kim
Hanyang Medical Reviews.2010; 30(4): 296. CrossRef
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Induction of Inducible Nitric Oxide Synthase Expression by Manganese in C6 Glioma Cells
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Gyeong Im Yu, Dong Hyul Lee, In Sung Chung, Mi Young Lee, Dong Hoon Shin
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Korean Journal of Occupational and Environmental Medicine 2009;21(3):259-266. Published online September 30, 2009
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DOI: https://doi.org/10.35371/kjoem.2009.21.3.259
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Abstract
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- OBJECTIVE: It is well established that manganese neurotoxicity is associated with clinical symptoms similar to those of idiopathic Parkinson's disease. Recent research has shown that the exposure to manganese (MnCl2) leads to induction of iNOS in BV2 microglial cells via iNOS transcriptional up-regulation and activation of both MAPKs and PI3K/Akt signaling pathways. Here, we further investigated the effect and the action mechanism of MnCl2 on iNOS expression in C6 glioma cells.
METHODS
Western blot analyses demonstrated that treatment with MnCl2 at 250 micronmeter was sufficient to induce iNOS at both the protein and mRNA levels in C6 cells.
RESULTS
These studies demonstrated that the induction of iNOS protein and mRNA was visible after 4h- and 2 h-treatment with MnCl2, respectively. MnCl2 treatment led to strong phosphorylation of JNKs and ERKs, members of MAP kinases (MAPKs), and Akt, a PI3-kinase (PI3K) downstream effector, in C6 cells. MnCl2 treatment had no effect on I kappa B-alpha in C6 cells. Notably, pretreatment with LY294002 (a PI3K inhibitor), which inhibited phosphorylation of Akt by MnCl2, caused strong suppression of MnCl2- induced iNOS protein and mRNA expression in C6 cells. Moreover, pretreatment with SP600125 (an inhibitor of JNKs) and PD98050 (an inhibitor of ERKs), which respectively interfered with MnCl2-mediated phosphorylation of JNKs and ERKs, led to the partial suppression of MnCl2-induced iNOS protein. Interestingly, pretreatment with LY294002 inhibited phosphorylation of not only Akt, but also ERKs and JNKs, in response to MnCl2. Moreover, there was an effective suppression of MnCl2-mediated phosphorylation of AKT by SP600125.
CONCLUSION
These results collectively suggest that MnCl2 induces iNOS expression in C6 glioma cells via activation of PI3K/Akt and JNK-ERK MAPK signaling proteins, whose activations seem to be mutually interconnected in response to MnCl2.
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