Annals of Occupational and Environmental Medicine

Cheol In Ryu

5 Articles

Nasal Septum Perforation of Welders: Choong Ryeol Lee, Cheol In Ryu, Ji Ho Lee, Jeong Hak Kang, Seong Kyu Kang, Jung Sun Yang, Yong Cheol Shin; Korean Journal of Occupational and Environmental Medicine 1998;10(3):404-411. Published online August 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.3.404

Six cases of nasal septum perforation were found among welders during periodic physical checkup in 1997. Considering the size, shape and margin, the perforations were assumed to have been occurred several years before of which the diameter were 8~15 mm. To investigate the cause of perforation, we reviewed the past history of preemployment, the results of annual working environment survey and the material safety data sheets of welding rods and steels with which they have dealt, and analyzed the concentration of several metals of welding fume and the concentration of blood and urinary chromium. In the result, we presupposed that the nasal septum perforations of welders were due to chronic exposure to low level hexavalent chromium and/or nickel, and report these cases with literatures review.

Citations

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Changes of Glycoconjugate Expression in Nasal Respiratory Mucosa of Rats Exposed to Welding Fumes
Gil Nam Jeong, Un Bock Jo, Il Je Yu
Inhalation Toxicology.2007; 19(12): 987. CrossRef
Effects of repeated welding fumes exposure on the histological structure and mucins of nasal respiratory mucosa in rats
Gil Nam Jeong, Gi Jin Jo, Un Bock Jo, Il Je Yu
Toxicology Letters.2006; 167(1): 19. CrossRef

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Type of Anemia Due to Organic Solvents: Choong Ryeol Lee, Cheol In Ryu; Korean Journal of Occupational and Environmental Medicine 1998;10(2):180-188. Published online May 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.2.180

Abstract PDF: The purpose of this study Is whether we can presuppose the correlation between some type of anemia and exposure to organic solvents using some hematologic index such as MCV, RDW and MCHC. The authors conducted the hematological examination of 160 male workers who were exposed organic solvents and those of 167 control workers. The type of anemia was slightly macrocytic anemia, and the RDW was generally homogenous in workers exposed to organic solvents whereas those of control were normocytic and homogenous.

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A Study on the Hematologic Changes of Workers Exposed to Mixed Organic Solvents: Choong Ryeol Lee, Cheol In Ryu; Korean Journal of Occupational and Environmental Medicine 1997;9(4):549-564. Published online December 31, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.4.549

Abstract PDF: The purpose of this study is to evaluate the hematological changes of workers exposed to mixed organic solvents and to search the organic solvent that bring out these changes. The study participants were 1,605 workers, consisting 1,088 workers (male 989, female 99) exposed to mixed organic solvents and 517 non-exposed workers (male 431, female 86). The authors analyzed the results of complete blood count and differential count of leukocytes of all the workers and examined all of the material safety data sheets of substances with which they dealt and the results of their working environmental surveys during the last 3 years. The results were as follows: 1. The mean values of complete blood count in workers exposed to mixed organic solvents were lower than that of non-exposed workers in WBC, RBC, hemoglobin and hematocrit in cases of male and RBC, hemoglobin and hematocrit in cases of female, but the mean value of platelet count in male exposed workers and WBC count in female exposed workers were higher than those of non-exposed workers. 2. The distribution of differential count of leukocytes showed no difference between exposed workers and non-exposed workers. 3. The correlation coefficients between age and duration of employment and WBC showed statistically a positive value and that between age and duration of employment and RBC, hemoglobin, hematocrit showed a statistically negative value in cases of male exposed to mixed organic solvents. But in cases of female there was no statistical correlation between them. 4. In cases of male the proportions of workers with subnormal levels of WBC, RBC, hemoglobin, hematocrit and platelet according to the standard of classification were high or than those of non-exposed workers. The proportions of exposed workers were 3.6 %, 18.6 %, 5.3 %, 32.7 % and 1.4 % respectively and those of non-exposes workers were 2.8 %, 10.7 %, 2.1 %, 13.9 % and 0.2 % respectively. 5. In cased of female the proportion of workers with subnormal levels of RBC, hemoglobin and hematocrit according to the standard of classification were higher than those of non exposed workers. The proportion of exposed workers were 42.4 %, 55.6 % and 41.4 % respectively and those of non-exposed workers were 10.5 %, 11.6 % and 8.1 % respectively. 6. The number of substances with which workers exposed to mixed organic solvents dealt were about 500, and 22 organic solvents such as xylene, toluene, isopropyl alcohol, 2-ethoxyethanol and 2-ethoxy ethyl acetate were main components of substances according to the material safety data sheet and working environmental surveys during the last 3 years. The authors suspect 2-ethoxyethanol and 2-ethoxy ethyl acetate of the organic solvents, which bring out the hematological changes of workers exposed to mixed organic solvents. As a result of this study, the authors confirmed the hematological changes of workers exposed to mixed organic solvents and recommend : strict management of working environment, working time and the protective equipments of workers exposed to mixed organic solvents.

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Alterations of immune response in workers occupationally exposed tolead: Cheol In Ryu, Byung Mann Cho, Ji Ho Lee, In Kyung Hwang, Su Il Lee, Don Kyoun Kim; Korean Journal of Occupational and Environmental Medicine 1991;3(2):135-144. Published online November 30, 1991; DOI: https://doi.org/10.35371/kjoem.1991.3.2.135

Abstract PDF: No abstract available.

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A Study on the Urinary Metabolites and Sister Chromatid Exchanges of Peripheral Lymphocytes in Workers Exposed to the Organic Solvents: Don Kyoun Kim, In Kyung Hwang, Cheol In Ryu, Su Il Lee, Kap Yul Jung, Yong Hwan Lee, Choong Ryeol Lee, Won Il Hyun, Suk Bong Kim, Yong Duk Jeon; Korean Journal of Occupational and Environmental Medicine 1990;2(1):75-83. Published online February 28, 1990; DOI: https://doi.org/10.35371/kjoem.1990.2.1.75

Abstract PDF: In order to know the possibility of utilizing the sister chromatid exchanges as an index which could evaliiate the effect of organic solvents on Lhe health in industrial workers, the authors Studied the effects of the inductivity of sister chromatid exchanges in peripheral lymphocyces from 90 female workers espoxed to organic solvents .and 20 lion-exposed female workers. The results obtained were as follows: 1. The frequency of sister chromatid exchanges in peripheral iympnocytes from 90 female workers exposed to organic solvents was significantly increased in comparison with 20 coatiol subiect. 2. The frequency of sister chromatid exchanges was significantly Increased in the workers who were employed in the manufacture of plastic materials than the other manufactures. 3. There were no significant differences in the frequency of sister chrornatid exchanges by carriera of the exposed workers. 4. The correlation between the frequency of sister chromatid exchanges and urinary hippuric acid was significant with the coefficient of 0.5902 showing Y=1.867X+15.188 in which Y indicate the frequency of sister chromatid exchanges per cell and X indicate the urinary hippuric acid concentration by g/l.

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