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Effect Assessment of Worksite-based, Post-examination, Health Care Management System
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Kang Jin Lee, Young Hee Choi, Cha Jae Oh, Hoo Rak Lee, Hyoung June Im, Moon Young Hwang, Byung Mann Cho, Ji Ho Lee
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Korean Journal of Occupational and Environmental Medicine 2006;18(1):1-14. Published online March 31, 2006
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DOI: https://doi.org/10.35371/kjoem.2006.18.1.1
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 Abstract
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- OBJECTIVES
This study was conducted to develop a worksite-based, post-examination, health care management system for continuous and systematic management of workers with hypertension, diabetes mellitus, hyperlipidemia, and abnormal LFT detected by periodic health examination and to assess the effectiveness such a system as an intervention study.
METHODS
Study subjects were selected from workers with hypertension, diabetes mellitus, hyperlipidemia, and abnormal LFT according to the selection criteria. The intervention group, but not the control group, received medical treatment of disease, follow up examination, and health education which consisted of information about the disease and the importance of life-style modification through periodic interview using the resources of occupational health service center in the worksite. To assess the effectiveness of this system, we compared follow up examination data from the intervention group with periodic examination data from the worksite control group.
RESULTS
In the intervention group a significant reduction trend was recorded for systolic and diastolic blood pressure, fasting blood sugar, postprandial 2 hour glucose, total cholesterol, triglyceride, LDL-cholesterol, AST, ALT, and gamma-GTP, and a rising trend for HDL-cholesterol. Significant group differences ware recorded for fasting blood sugar, postprandial 2 hour glucose, total cholesterol, AST, and ALT.
CONCLUSIONS
The worksite-based, post-examination, health care management system was effective for the continuous and systematic management of workers who had abnormal findings detected by periodic health examination.
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Citations
Citations to this article as recorded by  - The Change Analysis about Health Behavior and Examination Result of Periodical Medical Examiner
Tae-Yong Lee, Dal-Sik Yoon
Journal of the Korea Academia-Industrial cooperation Society.2014; 15(2): 923. CrossRef - The Effect of Metabolic syndrome Management Program Applying Participatory Action-Oriented Training Principle
Seong-Yong Yoon, Kuck-Hyeun Woo, Hwa-Sung Kim, Yong-Bae Kim, Jin-Seok Kim, Seong-Yong Jo, Sung-Soo Lee
Korean Journal of Health Education and Promotion.2014; 31(5): 81. CrossRef - The Effects of Hypertension Self-help Program on Hypertension-related Knowledge, Self-efficacy, Self-management Compliance and Physiological Parameters in Workers
Mi-Young Gi, Young-Hae Park
Korean Journal of Occupational Health Nursing.2012; 21(1): 1. CrossRef
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The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1
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Cha Jae Oh, Moon Young Hwang, Kang Jin Lee, Hoo Rak Lee, Byung Mann Cho
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Korean Journal of Occupational and Environmental Medicine 2005;17(2):85-94. Published online June 30, 2005
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DOI: https://doi.org/10.35371/kjoem.2005.17.2.85
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Abstract
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- OBJECTIVES
To investigate effects of genetic polymorphism of glutathione S-transferase M1 (GSTM1), glutathione S-transferase T1 (GSTT1), glutathione S-transferase P1 (GSTP1), N-acetyltransferase (NAT2), cytochrome P450 2E1 (CYP2E1) and cytochrome P450 1A1 (CYP1A1) on pneumoconiosis.
METHODS
Eighty-five pneumoconiosis patients and 122 age and sex matched healthy controls were enrolled. Direct interview and standard questionnaire were conducted and the genotypes of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1 were investigated using multiplex PCR or PCR-RFLP methods with DNA extracted from venous blood. The relationship was investigated between the severity of pneumoconiosis and the polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1, and also with various environmental factors including smoking.
RESULTS
We observed a significantly higher rate of genetic polymorphism in pneumoconiosis patients than in normal subjects. The odds ratio (95% CI) of NAT2 was 2.09 (1.19-3.68). In addition, smoking was related significantly with pneumoconiosis (OR 2.89, 95% CI 1.40-5.95). In multiple logistic regression analyses, NAT2 and smoking were significant risk factors for the development of pneumoconiosis (OR 1.84, 95% CI 1.00-3.37; OR 2.98, 95% CI 1.40-6.35, respectively). The age of onset of the disease and smoking were significantly related with moderate or severe pneumoconiosis (OR 0.91, 95% CI 0.83-0.99; OR 6.94, 95% CI 1.54-31.30, respectively). However there was no significant difference between the rate of genetic polymorphism of GSTM1, GSTT1, GSTP1, CYP2E1 and CYP1A1 in the two groups.
CONCLUSION
NAT2 genetic polymorphism was higher in pneumoconiosis patients than in normal subjects. The age of onset of the disease and smoking were significantly related with pneumoconiosis. However, the genetic polymorphism of GSTM1, GSTT1, GSTP1, CYP2E1 and CYP1A1 was not related with development or severity of pneumoconiosis.
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