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Occupational Disease Surveillance System: Planning and Management
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Soo Hun Cho, Yun Chul Hong, Jong Han Leem, Seong Sil Chang, Byung Chul Chun
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Korean Journal of Occupational and Environmental Medicine 2001;13(1):10-17. Published online March 31, 2001
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DOI: https://doi.org/10.35371/kjoem.2001.13.1.10
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- No abstract available.
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- Management System of Occupational Diseases in Korea: Statistics, Report and Monitoring System
Kyung Yong Rhee, Seong Weon Choe Journal of Korean Medical Science.2010; 25(Suppl): S119. CrossRef
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Plasma Malondialdehyde, alpha-tocopherol and Erythrocyte Superoxide Dismutase Activity with Blood Level of Heavy Metals in Welders
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Won Jin Lee, Cheon Hyun Hwang, Soung Hoon Chang, Byung Chul Chun, Hae Joon Kim
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Korean Journal of Occupational and Environmental Medicine 1998;10(2):240-250. Published online May 31, 1998
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DOI: https://doi.org/10.35371/kjoem.1998.10.2.240
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- We investigated the association between the oxidative stress and the concentration of heavy metals in blood among welders. The study subjects were male manual CO2 welders(N=127) exposed to several heavy metals. The age distribution was from 20 to 63 (GM=33.7) and the geometric mean(GM) of work duration was 4.2 years. We analyze the level of blood lead, cadmium, managese and chromium which was related with the oxidative stress in the animal studies. Blood selenuim, plasma malondialdehyde (MDA), plasma alpha-tocopheol and orythrocyte superoxide dismutase (SOD) were analyzed as biological markers of the oxidative stress. The results of univariate analysis showed that the plasma MDA was significantly correlated with D-tocopherol (r=0.327) and blood selenium (r=0.313) concentration. But we could not find out any relationship between the erythrocyte SOD activities and those metal concentrations. Neither smoking nor alcohol consumption was related to the level of heavy metals and the oxidative stress biomarkers. As the results of multiple regression analysis with stepwise selection method, 1) the change of MDA level were dependant with the level of alpha-tocopherol and blood selenium concentration (R2=19.7), 2) the plasma alpha-tocopherol level was dependant with MDA and blood chromium concentration (R2=15.6), 3) in case of erythrocyte SOD activity, only the duration of work was significantly selected.
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Vibration Perception Threshold of Male Workers Exposed to Carbon Disulfide
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Seung Hoi Park, Eun Il Lee, Byung Chul Chun, Yong Tae Yum, Jae Wook Chi
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Korean Journal of Occupational and Environmental Medicine 1996;8(1):85-96. Published online February 29, 1996
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DOI: https://doi.org/10.35371/kjoem.1996.8.1.85
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- This study was conducted on 367 male workers to evaluate the change of vibration perception threshold (VPT) according to exposure degree to carbon disulfide. VPT was measured on both metacarpal bones of index and little fingers and on fibular malleoli by Vibrometer (Rion, on 125Hz). The exposure degree was classified by the name of department. Workers in department 1 had been exposed to high concentration of carbon disulfide, those in. department 2 had been exposed to carbon disulfide moderately or intermittently, and those in department 3 had been exposed to undetectable concentration of carbon disulfide. The results were as follows: 1. The mean values of VPT of metacarpal(MC) bones showed dose-response pattern, i.e., the mean values of VPT at department 1 were highest, and those of VPT at department 3 were lowest with similar work duration or age. But the mean values of VPT of fibular malleoli (FM) showed dose-response pattern only in workers having above 5 years of work duration or whose age were above 30. 2. The mean values of VPT of MC bone of workers increased by age. 3. There were statistically significant difference in mean values of VPT of MC bone only in workers having 5-10 year work duration. And there were statistically significant difference of mean values of VPT of left 2nd and 5th MC bone in workers whose age was 30's, of right 2nd MC bone in those whose age was 40's, and of left 2nd MC bone in those whose age was 50's. 4. The variables affecting VPT significantly were department and age (or age group) both in multiple regression and general linear model. The department showed to have more effect to VPT than age in multiple regression, but age group showed to have more effect to VPT than department in general linear model. 5. The variables were transformed to indicator variable to do logistic regression analysis. Department 1, 2, 3 were classified into high exposure (spinning department) and low exposure (other department), age was classified into old (above 30) and young, and work duration was classified into long(above 10 years) and short. The exposure and age were significant variables by logistic regression analysis. Odds ratios of department and VPT on metacarpal bones or malleoli were 2.7-3.2 and those of age and VPT were 2.6 or 2.7. Odds ratio of age and abnormality of VPT on'any point was 3.3(1.59-6.;8), and that of department and VPT was 2.8(1.5-5.5). We concluded that exposure of carbon disulfied was significantly associated with reduction of VPT regardless of age; and that the test of VPT would be useful tool for screening and early detection in neuropathy by carbon disulfide or other neurotoxic chemicals,even though it is simple and cheap.
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Citations to this article as recorded by
- Trans‐Cranial Doppler and Peripheral Sensory Threshold Tests for Carbon Disulfide Poisoning
Eunil Lee, Hun‐Jong Chung, Soon‐Duck Kim, Jong‐Tae Park, Donggeun Sul, Myung‐Hyun Kim Journal of Occupational Health.2001; 43(6): 307. CrossRef - Carbon Disulfide Poisoning in Korea with Social and Historical Background
Eunil Lee, Soonduck Kim, Haejoon Kim, Kwangjong Kim, Yongtae Yum Journal of Occupational Health.1996; 38(4): 155. CrossRef
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