-
Incidence of Dimethylacetamide Induced Toxic Liver Injury among Workers in a Synthetic Fiber Manufacturing Company
-
Yong Seok Jang, Seong Yong Yoon, Seong Yong Jo, Tae Sung Choi, Jay Young Yoo, Kuck Hyun Woo, Bong Goo Ha, Sang Jae Jung, Byung Yeol Chun, Jin Seok Kim
-
Korean Journal of Occupational and Environmental Medicine 2006;18(3):246-254. Published online September 30, 2006
-
DOI: https://doi.org/10.35371/kjoem.2006.18.3.246
-
-
Abstract
PDF
- OBJECTIVES
The main goal of this study was to find the incidence of the dimethylacetamide (DMAc) induced toxic liver injury among workers who were exposed to DMAc for about 5 years in a synthetic fiber factory. METHODS In our investigation, total 1,021 workers had been exposed to DMAc from 1st February, 2000 to 30th June, 2004. Among them, 24 workers who had initial abnormal hepatic enzyme level or was viral hepatitis B carrier were excluded. Finally, 997 DMAc exposed workers were followed up for their incidence of toxic liver injury. To find out DMAc induced toxic liver injury case, we carried out regular examinations including liver enzyme tests such as AST and ALT. RESULTS We followed up 997 workers and among them 72 cases coincided with our case definition. Incidence density method was 6.05 per 100 person-year. and, a cumulative incidence by life table method was 0.0965 within a year. The incidence of the DMAc-induced toxic liver injury peaked at 4 to 5 in weeks after employment. There was no toxic liver injury case within second week after exposure to DMAc. Five new cases developed in 2th to 3th week, 25 cases in 4th to 5th week, 14 cases in 6th to 7th week, 12 cases in 8th to 9th week, 5 cases in 10th to 11th week, 4 cases in 12th to 13th week, 4 cases in 14th to 15th week, 1 case in 16th to 17th week, 1 case in 30th to 31th week, and there was one case in 48th to 49th week. CONCLUSIONS The incidence rate of toxic liver injury was considerably high during the 1st year after a worker is placed. So it is needed to take careful monitoring of hepatic enzyme level for newly exposed worker.
-
Citations
Citations to this article as recorded by
- A review of life table applications and an introduction of its application method
Kyoungjin Shin, Boseung Choi Journal of the Korean Data and Information Science Society.2013; 24(6): 1159. CrossRef - Occupational Hepatic Disorders in Korea
Hyoung Ryoul Kim, Tae Woo Kim Journal of Korean Medical Science.2010; 25(Suppl): S36. CrossRef - Current status of liver diseases in Korea: Toxic and alcoholic liver diseases
Kyung-Ah Kim The Korean Journal of Hepatology.2009; 15(Suppl 6): S29. CrossRef
-
28
View
-
0
Download
-
3
Crossref
-
A Case of Exercise-induced Rhabdomyolysis with Hepatitis
-
Seong Ah Kim, Sang Je Jung, Chae Yong Lee, Bong Goo Ha, Ki Soo Park
-
Korean Journal of Occupational and Environmental Medicine 2006;18(1):67-72. Published online March 31, 2006
-
DOI: https://doi.org/10.35371/kjoem.2006.18.1.67
-
-
Abstract
PDF
- BACKGROUND
Rhabdomyolysis is a relatively rare disease caused by various factors and is characterized by skeletal muscle damage. While crush injury is the most common cause in Korea as well as other countries, overexertion is an important common cause among young men in daily life. Although exercise-induced rhabdomyolysis is already well published among athletes or military persons, there have been few reports in workers. CASE REPORT: We observed a 28-year-old male worker who had elevated liver transaminases during a periodic workers' health checkup. Although he did not exhibit the typical pattern of toxic hepatitis, we had to exclude any possibility of dimethylacetamide-induced hepatitis (DIH) because he had worked in a spandex-producing factory, which already had a history of many DIH cases over several years. We performed careful history taking, several laboratory tests, liver ultrasonography and liver biopsy. We also investigated the results of biological monitoring and air concentrations of dimethylacetamide. The findings from these examinations supported the clinical diagnosis of exercise-induced rhabdomyolysis with hepatitis. CONCLUSION This case demonstrates that exercise can induce rhabdomyolysis and hepatitis. This disease must be treated by prompt and appropriate management because it might develop more serious complications such as acute renal failure.
-
Citations
Citations to this article as recorded by
- Exercise-induced rhabdomyolysis mechanisms and prevention: A literature review
Jooyoung Kim, Joohyung Lee, Sojung Kim, Ho Young Ryu, Kwang Suk Cha, Dong Jun Sung Journal of Sport and Health Science.2016; 5(3): 324. CrossRef - Literature review of effect of work pattern (day shift and night shift) on worker's health
Ki-Youn Kim, Man-Su Cho, Won-Mo Gal Journal of the Korea Safety Management and Science.2013; 15(2): 1. CrossRef
-
20
View
-
0
Download
-
2
Crossref
-
Application of Participatory Action-Oriented Training (PAOT) to Small and Medium sized Enterprises for Prevention of Work-related Musculoskeletal Disorders
-
Seong Yong Yoon, Kuckhyeun Woo, Jinseok Kim, Jay Young Yu, Taesung Choi, Bong Goo Ha, Yongseok Jang, Seong Yong Jo
-
Korean Journal of Occupational and Environmental Medicine 2005;17(3):249-258. Published online September 30, 2005
-
DOI: https://doi.org/10.35371/kjoem.2005.17.3.249
-
-
Abstract
PDF
- OBJECTIVES
The purpose of this study was firstly to introduce a Participatory Action-Oriented Training (PAOT) program for the prevention of work-related musculoskeletal diseases (WRMSDs) in Small and Medium sized Enterprises in the Gumi Industrial Zone, and secondly to assess its effect. METHODS Two PAOT workshops to prevent WRMSDs were conducted with 39 volunteer participants from 10 companies selected (on a first-come, first-served basis) among 200 small- or medium-sized enterprises in Gumi. These companies had been provided with mandatory occupational health management agency services for Small and Medium sized Enterprises by an occupational medicine clinic. Each workshop consisted of 6 technical sessions and one closing ceremony. At the 1st session, the principles of each action checklist item were explained and an on-site checklist exercise was carried out. The 2nd to 5th sessions presented good example pictures on 4 subjects: material storage and handling, working environment, work organization and work-related welfare. Group discussions were carried out by the participants. In the final 6th session on the implementation of improvement, each participant was asked to present 6 action plans, 3 short-term and 3 long-term, for their own workplace improvement. RESULTS Overall, the participants worked out 47 real action plans, 27 short-term and 20 long-term, for improvement of their own workplaces. Three to 6 months after the workshops, through in-person visits to each company, it was confirmed that more than half of these 47 plans had been completed; 25 plans (53.2%) had been completed as planned, 8 (17.0%) were in processing, and 14 (29.8%) had not yet been put into practice. CONCLUSIONS The study findings confirmed that the PAOT program holds strong potential as an intervention method to prevent WRMSDs in Small and Medium sized Enterprises, although the final results have not been fully assessed yet.
-
Citations
Citations to this article as recorded by
- Effectiveness of participatory training for the promotion of work-related health and safety among Korean farmers
Jin-Seok KIM, Seong-Yong YOON, Seong-Yong CHO, Sang-Kyu KIM, In-Sung CHUNG, Hyeong-Soo SHIN INDUSTRIAL HEALTH.2017; 55(4): 391. CrossRef - Effectiveness of Participatory Action-Oriented Training (PAOT) Methods for the Management Metabolic Syndrome in Korean Manufacture Workers for Three-years
Jungsuk Lee, Sin Kam, Seongyong Yoon Korean Journal of Occupational Health Nursing.2016; 25(4): 384. CrossRef - Agricultural Labor Environment and Work Safety
Kyung-Suk Lee, Insoo Kim, Min-Tae Seo, Myungsun Ko, Kyung-Su Kim, Hye-Seon Chae, Dong-Phil Choi Journal of the Ergonomics Society of Korea.2016; 35(4): 205. CrossRef - The Effect of Metabolic syndrome Management Program Applying Participatory Action-Oriented Training Principle
Seong-Yong Yoon, Kuck-Hyeun Woo, Hwa-Sung Kim, Yong-Bae Kim, Jin-Seok Kim, Seong-Yong Jo, Sung-Soo Lee Korean Journal of Health Education and Promotion.2014; 31(5): 81. CrossRef - Development of an intervention to prevent work-related musculoskeletal disorders among hospital nurses based on the participatory approach
Soon-Lae Kim, Jong-Eun Lee Applied Ergonomics.2010; 41(3): 454. CrossRef - Participatory Action Oriented Training for Hospital Nurses (PAOTHN) Program to Prevent Musculoskeletal Disorders
Jong‐Eun Lee, Soon‐Lae Kim, Hye‐Sun Jung, Jung‐Wan Koo, Kuck‐Hyeun Woo, Miyong T. Kim Journal of Occupational Health.2009; 51(4): 370. CrossRef
-
24
View
-
0
Download
-
6
Crossref
-
A Case of Toxic Hepatitis in a Worker Exposed to a Cleansing Agent Mainly Composed of Methylene Chloride
-
Bong Goo Ha, Jin Seok Kim, Jay Young Yu, Kuck Hyun Woo, Jung Oh Ham, Seong Yong Yoon, Yong Seok Jang, Sang Je Jung
-
Korean Journal of Occupational and Environmental Medicine 2004;16(2):210-219. Published online June 30, 2004
-
DOI: https://doi.org/10.35371/kjoem.2004.16.2.210
-
-
Abstract
PDF
- OBJECTIVES
To report a case of toxic hepatitis in a worker exposed to a cleansing agent mainly composed of methylene chloride. METHODS A 27-year-old female worker who had worked in an inspection and packing position of semiconductor parts in a factory using methylene chloride as a metal cleansing solvent was hospitalized due to fever, chill and generalized aches. We evaluated her with blood tests, abdominal ultrasonographic scan and abdominal CT scan and also took her occupational history. RESULTS The patient showed acute hepatitis in blood and radiologic tests after admission. The serologic tests for viral hepatitis A, B, C and autoimmune hepatitis were negative. She had no history of significant alcohol use, recent medication or drug allergy. After admission, her symptoms were improved and liver enzyme levels(AST and ALT) were markedly reduced. She returned to her workplace after discharge. Thereafter, however, her previous symptoms were recurred and she was hospitalized again 2 days after returning to her workplace. After this second admission, she showed acute hepatitis in blood tests and her symptoms were improved and liver enzyme levels were markedly reduced with the same pattern as those of the first admission. On the 11th day of the second admission, liver enzyme levels were normalized and she was discharged from hospital. CONCLUSIONS We presume that this patient`s liver injury was related to the methylene chloride presence at her workplace due to her clinical symptoms, blood tests, radiologic tests and occupational history.
-
Citations
Citations to this article as recorded by
- Death Due to Acrylic Adhesive (Dichloromethane): A Case Report
Ho Bong Hyun, Jo Youn Park, Hyeong Sin Park, Jeong Hyun Hong, Myung Guon Ko, Hyun Wook Kang, Hyoung Soo Lim Korean Journal of Legal Medicine.2022; 46(4): 133. CrossRef - A case report of toxic hepatitis caused by chloroform in automotive parts manufacturer coating process
Jong Hyun Hwang, Jung Il Kim Annals of Occupational and Environmental Medicine.2022;[Epub] CrossRef - Occupational Hepatic Disorders in Korea
Hyoung Ryoul Kim, Tae Woo Kim Journal of Korean Medical Science.2010; 25(Suppl): S36. CrossRef
-
21
View
-
0
Download
-
3
Crossref
-
Ocular, Respiratory and Skin Symptoms Among Solderers Employed in Printed Circuit Board Assembly Units
-
Jay Young Yu, Kuck Hyeun Woo, Jin Seok Kim, Jung Oh Ham, Tae Sung Choi, Bong Goo Ha, Sang Je Jung, Shin Goo Park, Il Ryong Kim
-
Korean Journal of Occupational and Environmental Medicine 2001;13(4):423-435. Published online December 31, 2001
-
DOI: https://doi.org/10.35371/kjoem.2001.13.4.423
-
-
Abstract
PDF
- OBJECTIVES
This study was conducted to evaluate the prevalence of ocular, respiratory and skin symptoms among solderers and to investigate the relationship between symptom prevalence and exposure intensity. METHODS We analyzed 126 eligible participants out of a population of 146 male solderers who completed the symptom questionnaires. Fourteen symptoms including 'itchy and red eyes', 'itchy or prickly nose', 'sneezing', 'rhinorrhea', 'blocked nose', 'pricklythroat', 'foreign body sensation in throat', 'sudden bouts of coughing', 'exertional breathlessness ', 'wheezing', 'sputum production', 'itchy face or hands', 'acneiform eruptions on the face'and 'red spots on the face or hands'were contained. Blood lead levels of all the 126 participants were tested and the participants'own assessments of the health risk of soldering were collected. RESULTS Of the 14 investigated symptoms, 'sudden bouts of coughing'was significantly more prevalent in solderers who worked 4 hours or more a day than those who worked less than 4 hours a day, as for the other symptoms, there were no significant differences in the preva1ences related to daily soldering hours. 2.8% of the solderers considered the risk of flux exposure to be serious. The mean blood lead level was 6.05 microgram/dL (maximum 15.50 microgram /dL). CONCLUSIONS Soldering may increase the risk of respiratory symptoms. Further investigations on the hazards of soldering processes are warranted and solderers should be educated on these hazards.
-
Citations
Citations to this article as recorded by
- Skin Disease Among Staff in a Large Korean Nursing Home.
DEREK RICHARD SMITH, JAE-WOOK CHOI, DONG-SOO YU, MYUNG KI, CHUN-HWA OH, ZENTARO YAMAGATA The Tohoku Journal of Experimental Medicine.2002; 198(3): 175. CrossRef
-
28
View
-
0
Download
-
1
Crossref
|