Annals of Occupational and Environmental Medicine

Yong Jin Lee

4 Articles

A Study of Psychosocial Stress of Residents Near Asbestos Mines: Young Sik Shin, Yong Jin Lee, Jung Oh Ham, Eun Chul Jang, Chan Ho Park, Min Sung Kang, Seung Kwon Park; Korean Journal of Occupational and Environmental Medicine 2012;24(4):375-383. Published online December 31, 2012; DOI: https://doi.org/10.35371/kjoem.2012.24.4.375

Abstract PDF: OBJECTIVES
The purpose of this study is to identify the level of psychosocial stress of residents near asbestos mines, and to investigate the relationship between psychosocial stress and asbestos exposure history as well as, asbestos exposure awareness.
METHODS
The survey was conducted in 297 individuals, by one-on-one interviews with a standard questionnaire including demographic characteristics, health status, asbestos exposure history, and awareness of asbestos exposure. The levels of psychosocial stress were measured through the Psychosocial Wellbeing Index-Short Form(PWI-SF). Multivariate logistic regression was conducted using psychosocial stress as a dependent variable. Demographic characteristics, health status, asbestos exposure history, and asbestos exposure awareness were examined as independent variable.
RESULTS
The average PWI-SF score was 17.5 +/- 8.0, with 40 people (13.5%) in the high-risk stress group (PWI-SF 27 points or more). The group having an asbestos-related occupational history had a 2.53 times higher proportion of psychosocial stress (95% CI: 1.03~6.21). The group recognizing asbestos exposure had an even higher proportion of high psychosocial stress group (4.84 times, 95% CI: 1.41~16.55).
CONCLUSIONS
The incidence of psychosocial stress is significantly higher in residents near asbestos mines having an asbestos-related occupational history who recognize their frequent asbestos exposure. Therefore, mental health is affected by the awareness of environmental asbestos exposure as well as an occupational exposure to asbestos.

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The Prevalence of Asbestos Related Pleural Plaque among Residents Living Near Asbestos Mines in Korea: Yong Jin Lee, Chan Ho Park, Yong Bae Kim, Eun Chul Jang, Seung Hwan Kim, Young Sik Shin, Jeung Sook Kim; Korean Journal of Occupational and Environmental Medicine 2012;24(1):1-10. Published online March 31, 2012; DOI: https://doi.org/10.35371/kjoem.2012.24.1.1

OBJECTIVES
The investigation of the prevalence of pleural diseases in regards to those living within 1 km of 14 asbestos mines in Chungnam province.
METHODS
We enrolled 4,057 residents (male: 1,887, female: 2,170) living within 1km of asbestos mines in Chungcheong province. They received checkups from Soonchunhyang Environmental Health Center for asbestos related diseases between March 2009 and December 2009. Chest X-rays were taken from all subjects and read by two experts according to International Labor Organization guidelines. Those subjects suspected of asbestos related lesions were further checked with HRCT(high-resolution computed tomography). The determination was done by two experts after reviewing the resulting data.
RESULTS
The 4,057 exposed residents underwent the checkup, 859 of whom further underwent the HRCT(high-resolution computed tomography) check. The prevalence of pleural plaque was found to be 11.3% (29.2% non-occupational, 8.0% occupational) from the chest X-rays. The HRCT(high-resolution computed tomography) results revealed that 227 subjects (26.4%) out of the 859 positive subjects (110 (18.8%) non-occupational, 117 (42.9%) occupational) showed evidence of pleural plaque. The statistical analysis showed that the prevalence of pleural plaque increased with increases in age, residence time, and occupational family exposure to asbestos (p<0.05).
CONCLUSIONS
We recommend better control of asbestos in the soil and mines. We also recommend that all affected residents living near asbestos mines receive medical checkups as mandated by the asbestos health damage relief policy.

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Incidence of Cancer and Asbestos-Related Diseases among Residents Living near Abandoned Asbestos Mines in South Korea: A Retrospective Cohort Study Using National Health Insurance Database
Kyeongmin Kwak, Kyung Ehi Zoh, Domyung Paek
International Journal of Environmental Research and Public Health.2021; 18(3): 875. CrossRef
Exposure Assessment and Asbestosis Pulmonum among Inhabitants near Abandoned Asbestos Mines Using Deposited Dust
Hoki Ahn, Wonho Yang, Young Hwangbo, Yong Jin Lee
Korean Journal of Environmental Health Sciences.2015; 41(6): 369. CrossRef

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A Case Study on the Effect of Chelation Therapy with Dimercaptosuccinic Acid (DMSA) for Lead Poisoning in an Adult: Yong Jin Lee; Korean Journal of Occupational and Environmental Medicine 2010;22(1):69-76. Published online March 31, 2010; DOI: https://doi.org/10.35371/kjoem.2010.22.1.69

Abstract PDF

OBJECTIVES
We wanted to investigate the efficacy of dimercaptosuccinic acid (DMSA) for the treatment of lead poisoning in an adult.
METHODS
The chelation therapy was applied using oral DMSA after measuring the blood lead and performing, renal function tests, liver tests and a physical examination. This therapy with oral DMSA 30 mg/kg/day was administered three times a day for 5 days to an adult patient with a pre-chelation blood lead concentration of 75 microgram/dL. Testing was performed by assessing the daily blood lead level, the blood ZPP, the urine ALA, the symptoms and side effects were assessed by conducting a physical examination.
RESULTS
DMSA therapy given for the duration of 5 days reduced the blood lead concentration from 75 microgram/dL to 21.8 microgram/dL. The blood ZPP concentration fell from 366 microgram/dL to 300 microgram/dL. The urine ALA concentration fell from 9.71 mg/L to 0.38 mg/L. In addition, the symptoms of headache, dizziness and abdominal pain that were induced by lead were improved after 2 days of chelation therapy. The vomiting did not improve after 5 days of chelation therapy, but this resolved 14 days following cessation of therapy. No adverse effects of DMSA therapy were seen.
CONCLUSIONS
Oral chelation therapy with DMSA 30 mg/kg/day is possible without being admitted to a hospital and it is generally effective, safe, and relatively inexpensive. DMSA provides a positive effect on adult patients who have lead poisoning.

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Probit analysis of comparative assays on toxicities of lead chloride and lead acetate to in vitro cultured human umbilical cord blood lymphocytes
Rajashree Patnaik, Rabindra N. Padhy
Interdisciplinary Toxicology.2015; 8(1): 35. CrossRef
A Case of Lead Poisoning with Drug-induced Liver Injury after Ingestion of Herbal Medicine
Gi Jung Jeon, Jongha Park, Min Sung Kim, Jong Won Yu, Jae Hyun Park, Min Sik Kim
The Korean Journal of Gastroenterology.2015; 65(6): 375. CrossRef

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Effect of Soft Drink on Urinary Hippuric Acid Excretion in Workers Exposed to Low dose Toluene: Yong Jin Lee; Korean Journal of Occupational and Environmental Medicine 2004;16(4):475-487. Published online December 31, 2004; DOI: https://doi.org/10.35371/kjoem.2004.16.4.475

Abstract PDF

OBJECTIVES
To investigate the effect of soft drink containing benzoic acid on the excretion of urinary hippuric acid after ingestion of soft drink containing benzoic acid before working (Edthe deleted section is not an objective).
METHODS
Fifty workers (male, 35; female, 15) exposed to toluene in Choongchung province area were studied. Urinary samples were collected on two days. On the first day, all study subjects were required to avoid any soft drink containing benzoic acid for the 24-hour period before urine collection. After emptying their bladder before starting work, the total volume of urine for the full shift period was collected and spot urine was collected at the end of the shift. On the second day, all workers were provided with soft drink containing benzoic acid before the shift and the same urine collection procedure was applied as on the first day. The air concentrations of toluene for each workers was measured with personal air sampling with 3M organic solvent badge. Personal informations such as age, sex, smoking and drinking habit were collected by self-administered questionnaire method.
RESULTS
The geometric mean of urinary hippuric acid without ingestion of soft drink containing benzoic acid was 0.49+/-0.45 g/g creatinine in total volume urine, and 0.51+/-0.53 g/g creatinine in spot urine, whereas the equivalent results with ingestion of soft drink were increased to 0.92+/-0.61 g/g and 0.96+/-0.78 g/g, respectively. Stepwise multiple regression of urinary hippuric acid with air concentration of toluene, benzoic acid and other covariates revealed that 49% and 11% of urinary hippuric acid concentration in total volume urine analysis were attributed to the air concentration of toluene and benzoic acid, respectively, compared to 45% and 6% in spot urine analysis, respectively. On the other hand, taking the difference of urinary hippuric acid before and after ingestion of soft drink containing benzoic acid as a dependent variable and taking the air concentration of toluene, benzoic acid and other covariates as independent variables, stepwise multiple regression analysis revealed that 14% and 13% of urinary hippuric acid concentration in total volume urine analysis were attributed to the air concentration of toluene and benzoic acid, respectively, whereas only 9% of urinary hippuric acid concentration in spot urine analysis was attributed to the air concentration of toluene, (Ed- note that there is no respective comparison here).
CONCLUSION
Soft drink containing benzoic acid significantly affected the level of urinary hippuric acid after ingestion of soft drink before working. It is recommended that for the accurate elevation of urinary hippuric acid as an index of toluene exposure, detailed information on soft drink containing benzoic acid needs to be checked in the process of the health examination of toluene exposure workers.

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Effects of Factors Associated with Urine Hippuric Acid Correction Values in Urinary Creatinine by HPLC and Jaffe Method and Specific Gravity HPLC Jaffe Method
Key-Young Kim, Jong-Gyu Kim, Ki-Nam Yoon, Wha-Me Park, Hun-Hee Park
Journal of Korean Society of Occupational and Environmental Hygiene.2015; 25(4): 493. CrossRef

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