Annals of Occupational and Environmental Medicine

Jin Ha Kim

10 Articles

Epidemiologic Characteristics of Occupational Lung Cancer in the Busan area: Jung Il Kim, Jin Ha Kim, Dongmug Kang, Jung Won Kim, Jong Eun Kim, Jin Hong Ahn, Chang Hoon Lee, Hyun Jae Lee, Jin Uk Kang, Jin Kun Son, Jin Kon Sul, Young Ki Kim, Kap Yeol Jung, Joon Youn Kim; Korean Journal of Occupational and Environmental Medicine 2006;18(1):53-58. Published online March 31, 2006; DOI: https://doi.org/10.35371/kjoem.2006.18.1.53

OBJECTIVES
The objectives of this study were to estimate the proportion of occupational lung cancer in the Busan area.
METHODS
Occupational physicians of four university hospitals operating an occupational disease surveillance system in the Busan area actively interviewed all of the newly diagnosed, lung cancer cases about their characteristics and occupational histories through a survey questionnaire and chart review. To evaluate and agree on the work-relativity, the cases were presented in periodic meetings.
RESULTS
A total of 301 lung cancer cases were interviewed, of which 50 (16.6%, all male, 27 probable and 23 possible) were related to occupational exposure. The exposure materials were asbestos, Cr, PAH etc. Pathologic findings included squamous cell carcinoma, adenocarcinoma and small cell carcinoma.
CONCLUSIONS
The proportion of occupational lung cancer cases above the probable level was 9% and above the possible level was 17%. To develop the public health policy and to prevent further cancer death, the meaningful data from occupational cancer surveillance systems should be collected continuously for ongoing monitoring.

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Overview of occupational cancer in painters in Korea
Jun-Pyo Myong, Younmo Cho, Min Choi, Hyoung-Ryoul Kim
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef
Decision Tree of Occupational Lung Cancer Using Classification and Regression Analysis
Tae-Woo Kim, Dong-Hee Koh, Chung-Yill Park
Safety and Health at Work.2010; 1(2): 140. CrossRef

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A Case of Acute Toxic Hepatitis induced by brief exposure to Dimethylformamide: Jong Rae Roh, Jin Gun Sohn, Jin Ha Kim, Sun Ja Park; Korean Journal of Occupational and Environmental Medicine 2005;17(2):144-148. Published online June 30, 2005; DOI: https://doi.org/10.35371/kjoem.2005.17.2.144

Abstract PDF

Dimethylformamide (DMF), a widely used industrial solvent, has been reported to induce subtle to clinically overt hepatotoxicity. Liver injury due to occupational exposure through inhalation and skin contact has been sporadically reported. We report a 23-year-old male who developed intermittent abdominal pain, anorexia, nausea, vomiting, chest discomfort, and general weakness for 4 days after working in a plastic-coated-glove factory. An acute hepatitis episode occurred after working in an enclosed workplace for 3 days. Other causes of hepatitis such as viral, drug induced or alcoholic hepatitis, could be excluded or were considered to be unlikely. Based on occupational history, serological examination and serial liver function examinations, the case was compatible with DMF-induced acute toxic hepatitis. Hepatotoxicity due to occupational exposure to solvents (e.g., DMF) should be considered in any patient with unexplained hepatitis. The fast improvement of the clinical symptoms and the progressive normalization of the liver function tests once the DMF exposure has been stopped, supports the diagnosis.

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The potential health risks of N,N‐dimethylformamide: An updated review
Shu‐Jun Hong, Xiu‐Ning Zhang, Zhan Sun, Tao Zeng
Journal of Applied Toxicology.2024;[Epub] CrossRef
A case report of toxic hepatitis caused by chloroform in automotive parts manufacturer coating process
Jong Hyun Hwang, Jung Il Kim
Annals of Occupational and Environmental Medicine.2022;[Epub] CrossRef
Changes of 30 years in the recognized occupational diseases of Korea: Lessons from the system change perspective
Kyung Ehi Zoh, Mijin Park, Domyung Paek
Archives of Environmental & Occupational Health.2020; 75(3): 127. CrossRef
Compensation for Occupational Diseases by Chemical Agents in Korea
Soon-Chan Kwon, Soo-Yong Roh, Ji-Hoon Lee, Eun-A Kim
Journal of Korean Medical Science.2014; 29(Suppl): S78. CrossRef
Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology
Tae Hyun Kim, Sang Geon Kim
Safety and Health at Work.2011; 2(2): 97. CrossRef

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A Case of Malignant Pleural Mesothelioma Induced by Crocidolite: Jong Rae Roh, Jin Gun Sohn, Hye Ran Song, Jin Ha Kim, Jin Gon Seol; Korean Journal of Occupational and Environmental Medicine 2005;17(2):149-154. Published online June 30, 2005; DOI: https://doi.org/10.35371/kjoem.2005.17.2.149

Abstract PDF: Asbestos exposure may cause asbestosis, pleural plaques and benign pleural disease, and may give a predisposition to malignant mesothelioma in occupationally exposed workers. This case report describes a 50-year-old man, dying from histologically confirmed, diffuse, malignant mesothelioma after asbestos exposure. As a young man, he had been exposed at the workplace to crocidolite for 2 years, but he had no other known history of occupational or environmental asbestos exposure. The patient presented with chest pain and general weakness. Computed tomography showed bilateral irregular pleural thickening along both lower lateral chest walls and a low attenuating mass in the anterior portion of the left lobe. Pathological examinations revealed that it was an epithelial type with tubulopapillary structures and it tested immunohistochemically positive for antibodies against cytokeratin, calretinin and vimentin. The patient was started on chemotherapy but he died to the disease at ten months after the first onset of the symptoms. Mesothelioma is a rare neoplasm in the general population. Nevertheless, the importance of close medical surveillance of the high-risk population is emphasized, because of increased asbestos exposure.

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Occupational disease surveillance system in Busan, Ulsan, Kyung-Nam area: Jung Il Kim, Byung Gwan Kim, Jung Won Kim, Chang Ho Chae, Cheol Ho Yi, Dongmug Kang, Ji Hong Kim, Jin Ha Kim, Young Wook Kim, Young Ha Lee, Ji Ho Lee, Younghee Choi, Jung Ho Kim, Hyung Ryul Yun, Cheol In Yoo, Baek Geun Jeong, Tae Won Jang, Yun Gyu Kim, Dong Young Yun, Jin Uk Kang, Jong Eun Kim, Jin Hong Ahn, Dong Joon Lee, Joon Ho Jang, Kwang Young Lee, Hyu Ran Song, Yong Hwan Lee, Byung Man Cho, Hong Ryul Choi, Sang Baek Koh, Euna Kim, Yu Jin Lee, Young Seoub Hong, Kap Yeol Jung, Jung Man Kim, Joon Youn Kim; Korean Journal of Occupational and Environmental Medicine 2004;16(1):1-12. Published online March 31, 2004; DOI: https://doi.org/10.35371/kjoem.2004.16.1.1

Abstract PDF

OBJECTIVE: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases METHODS: 11 hospitals participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted.
RESULTS
Between Apri1 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. Most of the HAVS cases came from shipbuilding, and 172 of them (92.7 %) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9 %). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6 %) and 4 (12.1 %) cases of occupational asthma, the agents included isocyanate and welding fume, respectively. 64.7 % of the cases of occupational skin diseases were contact dermatitis, and organic solvents and welding fume were the main agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10 (58.8 %) of the cases were diagnosed as squamous cell carcinoma and 5 (29.4 %) as adenoma.
CONCLUSION
This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.

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Work-relatedness of lung cancer by smoking and histologic type in Korea
Young-Il Lee, Sang-Gil Lee, Dong-Mug Kang, Jong-Eun Kim, Young-Ki Kim, Jong-Han Leem, Hwan-Cheol Kim
Annals of Occupational and Environmental Medicine.2014;[Epub] CrossRef
Occupational Skin Diseases in Korea
Yeon-Soon Ahn, Min-Gi Kim
Journal of Korean Medical Science.2010; 25(Suppl): S46. CrossRef

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The occupational hazards of interns & residents during training: Hye Ran Song, Jin Ha Kim, Joo Hyun Byeon, Kaung Young Lee, Duck Hi Lee, Ho Chan Kim; Korean Journal of Occupational and Environmental Medicine 2003;15(3):213-223. Published online September 30, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.3.213

Abstract PDF

OBJECTS: Residents are exposed to various hazards and harassed by sleep deficiency due to overwork. This study was performed to outline the health condition of residents and develop the ways of improving it.
METHODS
A questionnaire was distributed to 881 army doctors who enrolled at the Korea Third Military Academy and The Armed Force Health Service School in 2000 with the exception of medical doctors who joined the armed service without going through intern and resident periods , dental and oriental medical doctors. 784 (89.0%) of the 881 questionnaires were returned of which 704 cases (79.9%). This should actually be 89.0% were regarded for analyses as being reliable data.
RESULTS
More than 20% of residents were exposed to radiation, laser, disinfectants, anesthetic gas, and anticancer drugs during their training periods with preventive measures for each of these hazards taken in about 10% of the cases of the lesser hazards but in about 35% for the hazards from radiation and laser. 91.1% of residents had experience of needlestick injuries during their training periods with over 36.3% being exposed to patients with infection during that time. The cases contracting HBV and HCV diseases due to pricking are 2.3 and 0.6% respectively. The average number of night duties per month during a one-year resident's period was about 19. The average sleeping time on duty during a one-year residents was less than 4 hours .28.4% of respondents were not satisfied with their occupation, 96.5% felt tired from overwork and 69.5% wanted to change their occupation to another that would pay the same salary.
CONCLUSION
Residents are exposed to harmful physical , chemical and biological factors, but the preventive care seldom undertaken. In addition, their overwork brings about lack of sleep which causes them problems when giving medical treatment to patients during their training periods. Despite the resident's interest in an occupation as a doctor, many intend to select other occupations if they can receive the same salary. According to the above results, preventative systems and measures should be prepared with environmental improvements for residents, and proper rewards for their overwork should be accomplished.

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Mental Health of Healthcare Workers who Experience Needlestick and Sharps Injuries
Jang‐Wook Sohn, Byoung‐Gwon Kim, Soo‐Hyun Kim, Changsu Han
Journal of Occupational Health.2006; 48(6): 474. CrossRef

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A study on the relationship between Alcohol Use Disorders Identification Test and liver function test in blue-collar workers: Jin Guhn Sohn, Hae Rhan Song, Kwang Young Lee, Jin Ha Kim, Ho Chan Kim; Korean Journal of Occupational and Environmental Medicine 2003;15(3):281-289. Published online September 30, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.3.281

Abstract PDF

OBJECTIVES
The purpose of this study was to investigate the usefulness of the Alcohol Use Disorders Identification Test (AUDIT) and the relationship between AUDIT score and liver function test.
METHODS
AUDIT questionnaires were distributed to 440 blue-collar workers. We compared liver function test with firstly, normal and hazardous drinking as defined by WHO, and secondly, with normal, hazardous and harmful drinking as measured by Kim et al.(1999). We also compared influencing factors on abnormal liver function.
RESULTS
By simple analysis in the normal BMI group, abnormal liver function was significantly affected by hazardous drinking (odds ratio 2.81) based on the guideline of WHO. By chi-square test for linear trend in the normal BMI group, abnormal liver function was significantly affected by hazardous drinking (odds ratio 1.23) and harmful drinking (odds ratio 2.14) based on the guideline of Kim et al.By multiple logistic regression analysis, abnormal liver function was significantly affected by AUDIT questionnaires No. 1-3 (odds ratio- high risk 2.39), age (odds ratio- thirties 1.95, forties 2.40, fifties 3.85), BMI (odds ratio- overweight 1.66, obesity 4.53), guideline by WHO (odds ratio- hazardous drinking 2.10), and guideline by Kim et al (odds ratio- harmful drinking 2.20) CONCLUSIONS: We found that the problem of alcohol drinking as measured by AUDIT was significantly associated with abnormal liver function. Therefore we suggest that AUDIT will be useful for the predictive test of abnormal liver function and screening test of hazardous and harmful drinking.

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Effects of nutrition education on nutrition-related knowledge, dietary habits, and nutrient intakes of alcoholic patients
An Na Kim, Hyeon-Sook Lim
Journal of Nutrition and Health.2014; 47(4): 277. CrossRef
Nutrient Intake Status of Korean Drinkers: Analysis of Data from Korea National Health and Nutrition Examination Survey (KNHANES), 2011
Hyung-Tae Kim, Sung-Soo Chun, Sun-Hee Joung, Mi-Eun Yun
Journal of the Korean Dietetic Association.2013; 19(4): 343. CrossRef
Psychometric Properties of the Alcohol Use Disorders Identification Test: A Korean Version
Sun S. Kim, Elsie E. Gulick, Kyoung A. Nam, Seong-Ho Kim
Archives of Psychiatric Nursing.2008; 22(4): 190. CrossRef

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Seasonal Variations of the Urinary N-Methylformamide Concentration among Workers at a Synthetic Leather Factory: Kwang Young Lee, Joo Hyun Byeon, Hae Rhan Song, Jin Ha Kim, Kwang Wook Ko, Yong Hwan Lee; Korean Journal of Occupational and Environmental Medicine 2003;15(2):162-172. Published online June 30, 2003; DOI: https://doi.org/10.35371/kjoem.2003.15.2.162

Abstract PDF

OBJECTIVES
This study was carried out to identify seasonal variations of urinary concentrations of N-methylformamide (NMF) among workers employed at a synthetic leather factory.
METHODS
Study subjects consisted of 16 male and 6 female workers who were involved in the direct treatment of dimethylformamide (DMF) in a synthetic leather factory. By using health examination data and the results of air measurements and biologic monitoring conducted in February and July, 2001, we identified seasonal variations of the DMF concentrations in the air and NMF concentrations in urine.
RESULTS
1) In winter and summer, average temperatures at the working sites were 3.2 degrees C and 26.5 degrees C, respectively and average humidities were 35.4 % and 84.5 %, respectively. 2) Airborne DMF concentrations were not significantly different between summer (13.78 ppm) and winter (11.55 ppm). 3) NMF concentrations in urine were found to be significantly higher in summer (96.09 mg/g creatinine) than in winter (31.23 mg/g creatinine) (p<0.001).
CONCLUSIONS
The seasonal difference in the urinary excretion values of NMF may be due to increased dermal absorption of DMF with the higher ambient temperature and humidity in summer and the increased area of exposed skin.

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Risk assessment of N,N-dimethylformamide on residents living near synthetic leather factories
Qingyu Zhang, Chanke Huang, Yumei Wei, Qi Zhu, Weili Tian, Cui Wang
Environmental Science and Pollution Research.2014; 21(5): 3534. CrossRef
Assessment of correlation between markers of ambient monitoring and biological monitoring of dimethylformamide for workers in synthetic leather manufacturing factories in Korea
Yang In Hwang, Mi-Young Lee, Yun Kyung Chung, Eun A Kim
Analytical Science and Technology.2013; 26(5): 315. CrossRef
Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology
Tae Hyun Kim, Sang Geon Kim
Safety and Health at Work.2011; 2(2): 97. CrossRef

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Neurobehavioral Tests in Workers Exposed to Ethylene Oxide: Kang Won Park, Young Gi Kim, Ju Hyun Byun, Jin Ha Kim, Young Hawn Lee, Kang Ryune Kim; Korean Journal of Occupational and Environmental Medicine 1998;10(3):301-309. Published online August 31, 1998; DOI: https://doi.org/10.35371/kjoem.1998.10.3.301

Abstract PDF: Ethylene oxide is widely used to sterilize heat-sensitive materials in hospital. Previous reports for neurotoxic effects of ethylene oxide have been described in animals and humans. To assess the exposure level and neurobehavioral effect of ethylene oxide, a cross-sectional study was performed to 27 nurses from central supply unit at hospital, exposed to ethylene oxide and 32 nurses as reference. Ethylene oxide was collected with using a personal air sampler and analyzed by gas chromatography for the determination of exposure level, and five items among Neurobehavioral Core Test Battery (NCTB) of World Health Organization, including Digit Span, Benton visual retention. Santa Ana dexterity, Digit Symbol and Simple reaction time, were administered to the exposed and reference group. The mean exposure level was 0.63 ppm in the exposed group and six subjects were exposed above the level of 1 ppm, which is currently regulated by the Korean Ministry of Labor. The results of neurobehavioral test in the exposed group showed significantly poorer performances in Digit Span forward and backward, Benton visual retention and Simple reaction time, comparing with the reference group. When the exposure level was divided into below and above the level of 1 ppm, there were significant differences in performance on Benton visual retentions, Digit Symbol and Simple reaction time. Also, Digit Span forward and backward showed significantly poorer performances below the level of 1 ppm, compared with reference group. Simple reaction time was still significantly delayed by the exposure level after controlling the confounding factors with multiple regression analysis. The results suggest that the periodic measurement of ethylene oxide in hospital and health care program is needed.

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Lead Levels in Maternal and Umbilical Cord Blood: Jin Ha Kim, Jong Kook Moon, Gang Won Park, Kang Woo Bae, Duk Hee Lee, Yong Hwan Lee; Korean Journal of Occupational and Environmental Medicine 1996;8(3):414-422. Published online December 31, 1996; DOI: https://doi.org/10.35371/kjoem.1996.8.3.414

Abstract PDF: This study was conducted to evaluate the blood lead levels in 141 pregnant women who were not occupationally exposed to lead and their umbilical cord, arid to identify some differences in blood lead levels by living area. ; The subjects-were all delivered at St. Benedict Hospital in Pusan and the blood lead levels were measured by graphite furance atomic absorption spectrophotometer. The summarized results were as follows. 1. The geometric mean lead levels in maternal and cord blood were 8.0+/-1.8microgram/dl, 5.0+/-0.6lmicrogram/dl respectively. 2. Lead levels in maternal (8.7+/-1.7microgram/dl) and cord blood(5.4+/-0.7microgram/dl) of industrial area(n=24) were higher than residential area(n= 124) which were 7.9+/-1.7microgram/dl and 5.0+/-0.6microgram/dl respectively (p<0.05). 3. Maternal blood lead concentration was significantly correlated to cord blood lead concentration (r=0.6090, p<0.001), but other variables (maternal age, paternal smoking, birth weight, etc) were not correlated.

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Blood Lead Levels in Children: Yong Hwan Lee, Duk Hee Lee, Jin Ha Kim, In Geun Park, Tae Young Han, She Han Jang; Korean Journal of Occupational and Environmental Medicine 1995;7(1):82-87. Published online February 28, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.1.82

Abstract PDF

The authors conducted this study to evaluate some differences in blood lead levels between inner-city and suburban children and obtain the basic data of the reference value of the blood lead concentrations in children. The subjects were composed of 102 children residing in inner-city and 86 children in suburban. Their age range were 6 to 8 years old and the obtained results were as follow; 1. The arithmetic means of the blood lead level in male and fenlale, male, and female children were 7.24, 7,40, 7.08 microgram/100ml, and geometric means were 6.92, 7.08, 6.76 microgram/100ml, respectively. 2. The children residing in inner-city had the higher blood lead levels both male and female than suburban children with statistical signficance (p < 0.05) 3. Seventeen percent of the total subjects had lead cencentrations ( 5 microgram/100ml, and 5.88% of inner-city children and 30.23 % of suburban children had this lead values. But in > or = 10 microgram/100ml group, the inner-city children (20.39 %) were more distributed than suburban chilren(2.33 %) , and 12.33 % of total subjects had this lead values.

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Effects of CO/CO2/NO on elemental lead adsorption on carbonaceous surfaces
Zhengyang Gao, Weijie Yang
Journal of Molecular Modeling.2016;[Epub] CrossRef

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