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The Relationship between the Occupational Exposure of Trichloroethylene and Kidney Cancer
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Inah Kim, Jaehyeok Ha, June-Hee Lee, Kye-mook Yoo, Jaehoon Rho
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Ann Occup Environ Med 2014;26:12-12. Published online June 3, 2014
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DOI: https://doi.org/10.1186/2052-4374-26-12
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Abstract
PDFPubReaderePub
Trichloroethylene (TCE) has been widely used as a degreasing agent in many manufacturing industries. Recently, the International Agency for Research on Cancer presented “sufficient evidence” for the causal relationship between TCE and kidney cancer. The aim of this study was to review the epidemiologic evidences regarding the relationship between TCE exposure and kidney cancer in Korean work environments. The results from the cohort studies were inconsistent, but according to the meta-analysis and case–control studies, an increased risk for kidney cancer was present in the exposure group and the dose–response relationship could be identified using various measures of exposure. In Korea, TCE is a commonly used chemical for cleaning or degreasing processes by various manufacturers; average exposure levels of TCE vary widely. When occupational physicians evaluate work-relatedness kidney cancers, they must consider past exposure levels, which could be very high (>100 ppm in some cases) and associated with jobs, such as plating, cleaning, or degreasing. The exposure levels at a manual job could be higher than an automated job. The peak level of TCE could also be considered an important exposure-related variable due to the possibility of carcinogenesis associated with high TCE doses. This review could be a comprehensive reference for assessing work-related TCE exposure and kidney cancer in Korea.
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- Occupational Inhalation Health Risk Assessment of TCE Exposure in the Korean Manufacturing Industry
Sueji Seo, Saemi Shin, Sanghoon Byeon Applied Sciences.2024; 14(13): 5510. CrossRef - Application of multiple occupational health risk assessment models in occupation health risk prediction of trichloroethylene in the electroplating and electronics industries
Shibiao Su, Zhiming Liang, Sheng Zhang, Haijuan Xu, Jinru Chen, Zhuandi Zhao, Meibian Zhang, Tianjian Wang International Journal of Occupational Safety and Ergonomics.2023; 29(1): 70. CrossRef - Time-concentration-dependent profile of histone modifications on human hepatocytes treated by trichloroacetic acid
Xinyue Peng, Susu Yu, Hui Lin, Fan Wu, Jiani Yang, Cheng Zhou, Luyun Zhang, Jianping Yang, Wenjuan Zhang International Journal of Environmental Health Research.2022; 32(11): 2376. CrossRef - Intracellular complement activation in podocytes aggravates immune kidney injury in trichloroethylene-sensitized mice
Xiaodong Yang, Wei Jiang, Meng Huang, Yuying Dai, Bodong Li, Xian Wang, Yun Yu, Tong Shen, Changhao Wu, Qixing Zhu The Journal of Toxicological Sciences.2020; 45(11): 681. CrossRef - DNA methyltransferase expression and DNA hypomethylation status in human hepatocytes following trichloroacetic acid exposure
Caiyun Lai, Jianji Gao, Zhiliang Zhu, Jianhui Yuan, Wenjuan Zhang, Jianping Yang Biochemical and Biophysical Research Communications.2019; 511(2): 266. CrossRef - Respiratory effects of trichloroethylene
Orianne Dumas, Thomas Despreaux, Frédéric Perros, Edmund Lau, Pascal Andujar, Marc Humbert, David Montani, Alexis Descatha Respiratory Medicine.2018; 134: 47. CrossRef - Review of refractory ceramic fiber (RCF) toxicity, epidemiology and occupational exposure
L. Daniel Maxim, Mark J. Utell Inhalation Toxicology.2018; 30(2): 49. CrossRef - Association between working time quality and self-perceived health: analysis of the 3rd Korean working conditions survey (2011)
Jaeyoup Jung, Gyuree Kim, Kyusung Kim, Domyung Paek, Sung-il Cho Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef - Mitochondrial Dysfunction, Disruption of F-Actin Polymerization, and Transcriptomic Alterations in Zebrafish Larvae Exposed to Trichloroethylene
Sara E. Wirbisky, Nur P. Damayanti, Cecon T. Mahapatra, Maria S. Sepúlveda, Joseph Irudayaraj, Jennifer L. Freeman Chemical Research in Toxicology.2016; 29(2): 169. CrossRef - Trichloroethylene-Induced DNA Methylation Changes in Male F344 Rat Liver
Yan Jiang, Jiahong Chen, Cong Yue, Hang Zhang, Tao Chen Chemical Research in Toxicology.2016; 29(10): 1773. CrossRef - Association Between Kidney Cancer and Occupational Exposure to Trichloroethylene
Morten Buhagen, Anna Grønskag, Siri Fenstad Ragde, Bjørn Hilt Journal of Occupational & Environmental Medicine.2016; 58(9): 957. CrossRef - Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea
June-Hee Lee, Inah Kim, Hongdeok Seok, Inhyo Park, Jungho Hwang, Jae-Oh Park, Jong-Uk Won, Jaehoon Roh Annals of Occupational and Environmental Medicine.2015;[Epub] CrossRef
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The Effects of Smoking and Drinking on Blood Lead and Cadmium Levels: Data from the Fourth Korea National Health and Nutrition Examination Survey
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Boram Lee, Jaehyeok Ha
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Korean Journal of Occupational and Environmental Medicine 2011;23(1):31-41. Published online March 31, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.1.31
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Abstract
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- OBJECTIVES
The purpose of this study is to assess the effects of smoking and drinking on blood lead and cadmium levels based on a dose-response relationship in the general Korean adult population. METHODS The study population consisted of 1,901 Koreans, who took part in the 2008 Korean National Health and Nutrition Examination Survey, in which blood lead and cadmium levels were measured. Geometric mean concentrations and their 95% confidence intervals of metals in blood were estimated by analysis of covariance (ANCOVA) adjusting for demographic and lifestyle factors. RESULTS We observed a statistically significant dose-response relationship with daily smoking amount/alcohol intake and blood lead/cadmium levels. While daily smoking amount was more consistent with blood cadmium level (0.1-0.2 microg/L per 5 cigarettes), blood lead concentrations were higher as daily alcohol intake increased (0.1-0.2 microg/dL per 10 gram of alcohol). CONCLUSIONS Our findings clearly support a relationship between daily smoking amount/alcohol intake and blood lead/cadmium levels, suggesting an additional reason towards efforts to reduce smoking and drinking habits.
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Sunmi Kim STRESS.2024; 32(1): 46. CrossRef - Association between Atopic Dermatitis and Hyperuricemia in the Adult Korean Population based on the 7th and 8th Korea National Health and Nutrition Examination Survey
Sunmi Kim Korean Journal of Health Promotion.2023; 23(4): 198. CrossRef - Relationship between Age-Related Macular Degeneration and Hyperuricemia Based on the 7th and 8th Korea National Health and Nutrition Examination Survey
Sunmi Kim Korean Journal of Clinical Geriatrics.2023; 24(3): 104. CrossRef - Exposure Assessment of Heavy Metals using Exposure Biomarkers among Residents Living Near a Chungcheongnam-do Province Industrial Complex Area
Yosub Joo, Sangchul Roh Korean Journal of Environmental Health Sciences.2016; 42(3): 213. CrossRef - Health Effect and Blood Lead Concentration among Residents in Gwangyang and Yeosu
Heejin Park, Myung-Kyu Park, Tack-Shin Kang, Geun-Bae Kim, Jong-Wha Lee, Bong-Ki Jang, Bu-Soon Son Korean Journal of Environmental Health Sciences.2016; 42(3): 205. CrossRef - Association of among alcohol consumption and blood vitamin D and lead concentrations: Based on 2010-2012 Korea national health and nutrition examination survey
Ho-Ki An, Jae-Yong Park, Hee-Jung Yoon Journal of the Korea Academia-Industrial cooperation Society.2015; 16(1): 498. CrossRef - Association between secondhand smoke exposure and blood lead and cadmium concentration in community dwelling women: the fifth Korea National Health and Nutrition Examination Survey (2010–2012)
Se Young Jung, Suyeon Kim, Kiheon Lee, Ju Young Kim, Woo Kyung Bae, Keehyuck Lee, Jong-Soo Han, Sarah Kim BMJ Open.2015; 5(7): e008218. CrossRef - Simultaneous Exposure to Heavy Metals among Residents in the Industrial Complex: Korean National Cohort Study
Heejin Park, Kyoungho Lee, Chan-Seok Moon, Kyungsook Woo, Tack-Shin Kang, Eun-Kyung Chung, Bu-Soon Son International Journal of Environmental Research and Public Health.2015; 12(6): 5905. CrossRef - A Study on Concentrations of Heavy Metal in Blood and Urine of Local Area in Korea
Ji-Young Im, Eun-Kyung Chung, Hee-Jin Park, Seungdo Yu, Bong-Ki Jang, Bu-Soon Son Journal of Environmental Science International.2013; 22(1): 59. CrossRef - Smoking Prevalence and the Association between Smoking and Sociodemographic Factors Using the Korea National Health and Nutrition Examination Survey Data, 2008 to 2010
Sungroul Kim Tobacco Use Insights.2012; 5: TUI.S9841. CrossRef - The association of heavy metals in blood, fish consumption frequency, and risk of cardiovascular diseases among Korean adults: The Korean National Health and Nutrition Examination Survey (2008-2010)
Ji-Ye Shin, Ji-Myung Kim, Yuri Kim Korean Journal of Nutrition.2012; 45(4): 347. CrossRef
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The Association between Nonstandard Employment and Suicidal Ideation: Data from the First~Fourth Korea National Health and Nutrition Examination Surveys
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Woncheol Lee, Jaehyeok Ha
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Korean Journal of Occupational and Environmental Medicine 2011;23(1):89-97. Published online March 31, 2011
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DOI: https://doi.org/10.35371/kjoem.2011.23.1.89
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Abstract
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- OBJECTIVES
In light of the high percentage of nonstandard workers and the high suicide rates in South Korea since the 1997 economic crisis, we examined the association between nonstandard employment and suicidal ideation among South Korean employees. METHODS We analyzed data from the Korean National Health and Nutrition Examination Surveys (KNHANES) I, II, III and IV, conducted in 1998, 2001, 2005 and 2007-2009, respectively (13,632 waged workers aged 20-69 years). Employment status was categorized into standard and nonstandard (part-time, temporary and daily) employment. Prevalence ratios (PRs) for self-reported suicidal ideation were compared between nonstandard and standard workers according to each survey wave. RESULTS After adjusting for background variables, the risk for suicidal ideation was consistently higher among nonstandard workers in every survey wave. In women, the PRs for suicidal ideation of nonstandard workers compared with standard ones were 1.24~1.37 and all of them were statistically significant. In men, those PRs were 1.36~1.52 with (marginal) statistical significance except for the First KNHANES (1998). Because nonstandard employment is closely related to other factors of suicidal ideation, these estimates are unlikely to have been underestimated. CONCLUSIONS The findings suggest the impact of employment status on suicidal ideation and the need for further prospective investigation that lead to policies aimed at improving the problematic labor markets.
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Hwanjin Park, Kounseok Lee Journal of Personalized Medicine.2022; 12(6): 945. CrossRef - Mental health and quality of life according to sleep in cancer survivors
Yoonjung Kim Perspectives in Psychiatric Care.2022; 58(4): 2442. CrossRef - Temporary employment and suicidal ideation in COVID-19 pandemic in Japan: A cross-sectional nationwide survey
Natsu Sasaki, Takahiro Tabuchi, Ryo Okubo, Tomohiro Ishimaru, Mayumi Kataoka, Daisuke Nishi Journal of Occupational Health.2022;[Epub] CrossRef - Sleep Duration Is Closely Associated with Suicidal Ideation and Suicide Attempt in Korean Adults: A Nationwide Cross-Sectional Study
Yujin Ko, Jieun Moon, Sangsoo Han International Journal of Environmental Research and Public Health.2021; 18(11): 5594. CrossRef - The Association between Unstable Employment and Suicidal Behavior in Young-Adult Precarious Workers
Yoanna Seong, Eun-Sun Lee, Subin Park Psychiatry Investigation.2021; 18(7): 661. CrossRef - Association of Bedtime with both Suicidal Ideation and Suicide Planning among Korean Adolescents
Wonjeong Jeong, Yun Kyung Kim, Hyeon Ji Lee, Jieun Jang, Selin Kim, Eun-Cheol Park, Sung-In Jang International Journal of Environmental Research and Public Health.2019; 16(20): 3817. CrossRef - Employment conditions and use of gastric cancer screening services in Korea: a nationwide survey
Hye-Young Shim, Jae Kwan Jun, Ji-Yeon Shin BMC Public Health.2019;[Epub] CrossRef - Long and short sleep duration are both associated with suicidal ideation in Korean employees
Young-Chul Shin, Jin-woo Kim, Jin-Mi Seol, Kang-Seob Oh, Dong-Won Shin, Eun-Jin Kim, Se-Won Lim Sleep and Biological Rhythms.2017; 15(1): 81. CrossRef - The Association between Unemployment and Suicidal Ideation by Gender - Using the Korea National Health and Nutrition Examination Survey 2009 -
Hyun-Kyung Lee, Hye-Sun Jung Korean Journal of Health Education and Promotion.2014; 31(5): 97. CrossRef - The Effects of Employment Conditions on Smoking Status and Smoking Intensity: The Analysis of Korean Labor & Income Panel 8th–10th Wave
Youn Jung, Juhwan Oh, Soonim Huh, Ichiro Kawachi, Chris Bullen PLoS ONE.2013; 8(2): e57109. CrossRef - Association between Total Sleep Duration and Suicidal Ideation among the Korean General Adult Population
Jae-Hyun Kim, Eun-Cheol Park, Woo-Hyun Cho, Jong-Yeon Park, Won-Jung Choi, Hoo-Sun Chang Sleep.2013; 36(10): 1563. CrossRef - Relationship between the Suicidal Ideation of the Married Women and the Characteristics of Their Children
Eunjung Kim, Sunmi Lee, Seungji Lim, Woojin Chung Health Policy and Management.2013; 23(4): 358. CrossRef
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Job Stress and Psychosocial Stress among Firefighters
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Jaehyeok Ha, Dong Il Kim, Byung Sung Seo, Won Sool Kim, Seungho Ryu, Soo Geun Kim
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Korean Journal of Occupational and Environmental Medicine 2008;20(2):104-111. Published online June 30, 2008
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DOI: https://doi.org/10.35371/kjoem.2008.20.2.104
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Abstract
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- OBJECTIVES
This study was performed to assess the level of job and psychosocial stresses in Korean firefighters, and to evaluate the determinants of psychosocial stress. METHODS The study subjects comprised 1,712 male firefighters working in Seoul, Busan, and Kyungnam in 2006. We collected information about demographic and job-related characteristics, healthrelated behaviors, Korean Occupational Stress Scale (KOSS), and psychosocial Well-being Index (PWI) through self-administered questionnaires. Statistical analyses were done by using the chi-square-test and logistic regression model. RESULTS The multiple logistic regression analyses indicated that the proportion of high-risk psychosocial stress is significantly higher in the groups with high job stress level in 'lack of rewards' (OR=2.90, 95% CI=2.18-3.85), 'occupational climate' (OR=1.92, 95% CI=1.47-2.51), 'job demand' (OR=1.72, 95% CI=1.32-2.23), 'job insecurity' (OR=1.53, 95% CI=1.17-2.01), 'interpersonal conflict' (OR=1.53, 95% CI=1.16-2.01), 'physical environment' (OR=1.45, 95% CI=1.11-1.89), and 'organizational injustice' (OR=1.38, 95% CI=1.04-1.85). CONCLUSIONS Psychosocial stress might be adversely influenced by job stressors for the most part. Firefighters need job stress management to minimize their psychological problems.
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Cement Burn from Waterproof Work: A Case Study
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Jaehyeok Ha, Soo Geun Kim, Min Gi Kim, Euna Kim
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Korean Journal of Occupational and Environmental Medicine 2008;20(2):127-131. Published online June 30, 2008
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DOI: https://doi.org/10.35371/kjoem.2008.20.2.127
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Abstract
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- BACKGROUND
Portland cement, which is a common material used in the construction industry, is known to cause caustic burns due to its alkalinity. Although cement burns are frequent and can be severe, many workers are inadequately aware of its risks. CASE A 39-year-old man presented with exudative lesions and pain on his right hand after working with wet cement during waterproof work. The patient stated that wet cement entered his protective glove and he did not wash the cement off for 3 hours. Debridement of necrotic tissue and skin grafting was performed on his second and fifteenth hospital day respectively. CONCLUSION The prevention of cement burns can be improved by extensive risk instruction and the provision of adequate skin protection.
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