Annals of Occupational and Environmental Medicine

Jae Yeon Jang

7 Articles

The Association of Exposure to Organic Solvents with Liver Function: Chi Young Ann, Kyung Jong Lee, Jae Bum Park, Jae Yeon Jang, Moon Jong Kim; Korean Journal of Occupational and Environmental Medicine 2001;13(1):64-74. Published online March 31, 2001; DOI: https://doi.org/10.35371/kjoem.2001.13.1.64

OBJECTIVES
This study was conducted to evaluate the association of cumulative exposure to organic solvent with liver function.
METHODS
We conducted a cross sectional study. 461 male workers who perform painting job at a shipyard and use organic solvents routinely and 125 workers of the same shipyard who never have been exposed to organic solvents were studied. All subjects who were confirmed not having HBsAg surveyed their age, BMI(body mass index), alcohol drinking and smoking history, and examined liver function test (SGOT, SGPT, gamma-GTP, Total protein, albumin, total bilirubin, direct bilirubin). The amount of cumulative exposure (CE) to mixed organic solvents were measured by biological monitoring method using their metabolites in urine.
RESULTS
The CE was observed as a significant variable with logistic regression analysis on abnormality of SGOT(>35IU/L), SGPT(>40IU/L) and gamma-GTP(>63IU/L), their odds ratio were 1.10 (95 %CI, 1.02-1.20), 1.10 (95 %CI, 1.01-1.19), and 1.10 (95 %CI, 1.01-1.19) each.
CONCLUSIONS
Therefore we suggest that the cumulative exposure to mixed organic solvents might be a significant variable on abnormal liver function indices (SGOT, SGPT,gamma-GTP) in male shipyard workers

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Liver function alterations among workers in the shoe industry due to combined low-level exposure to organic solvents
Nina Umicevic, Jelena Kotur-Stevuljevic, Vesna Paleksic, Danijela Djukic-Cosic, Evica Antonijevic Miljakovic, Aleksandra Buha Djordjevic, Marijana Curcic, Zorica Bulat, Biljana Antonijevic
Drug and Chemical Toxicology.2022; 45(4): 1907. CrossRef
Estimating Benzene Exposure Level over Time and by Industry Type through a Review of Literature on Korea
Donguk Park, Sangjun Choi, Kwonchul Ha, Hyejung Jung, Chungsik Yoon, Dong-Hee Koh, Seunghun Ryu, Soogeun Kim, Dongmug Kang, Kyemook Yoo
Safety and Health at Work.2015; 6(3): 174. CrossRef
The effect of exposure to a mixture of organic solvents on liver enzymes in an auto manufacturing plant
Saber Mohammadi, Amirhoushang Mehrparvar, Yasser Labbafinejad, Mir Saeed Attarchi
Journal of Public Health.2010; 18(6): 553. CrossRef

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Health Effects of Aircraft Noise on Residents Living Near an Airport: Kyung Jong Lee, Jae Beom Park, Jae Yeon Jang, Sun Mi Cho, Se Wi Lee, Jong Goo Kim, Soon Young Lee, Jong Ja Kwak, Ho Keun Chung; Korean Journal of Occupational and Environmental Medicine 1999;11(4):534-545. Published online December 31, 1999; DOI: https://doi.org/10.35371/kjoem.1999.11.4.534

Abstract PDF

Objectives
; This study was conducted to reveal the health effects of aircraft noise on the residents live near the military airport.
METHODS
We sampled systematically 87 residents as the high exposed group, 58 residents as the low exposed group according to the geographical distance from the airport. We also sampled 67 residents as the control group lived far from the airport. Noise levels were measured for conform the exposures. Self-administered questionnaires for symptoms, air conduction hearing threshold level, blood pressure blood cholesterol with health examinations, and SCL-90-R were introduced to get the data from the residents.
RESULTS
The Ld/n at the area near the airport was 72.4 dB, however that of control area was 67. 7 dB. The value of pure tone average, high pure tone average, and threshold of 4,000 Hz were decreased with exposure level significantly. Linear regression analysis showed that the noise exposure level of the airport was related to the hearing threshold at pure tone average, threshold of 4,000 Hz, and high pure tone average. The systemic and diastolic blood pressure showed dose-response relationship with noise exposure. The prevalence of hypertension was higher in exposed group, but not statistically significant. In linear regression, noise level was related to systolic and diastolic blood pressure with other variables such as age, sex, BMI (Body Mass Index), and family history of hypertension. SCL-90-R showed that exposed group had higher score significantly in neurotic and psychologic variable and felt the various somatic symptoms.
CONCLUSIONS
These results suggest that aircraft noise would influence hearing loss at low frequencies as well as 4,000 Hz and higher frequencies, systolic and diastolic blood pressure, and psychological response.

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Influence of noise exposure on cardiocerebrovascular disease in Korea
Myoungjin Oh, Kwangsoo Shin, Kyungah Kim, Jungwoo Shin
Science of The Total Environment.2019; 651: 1867. CrossRef
Study on the Health Status of the Residents near Military Airbases in Pyeongtaek City
Hyunjoo Kim, Sangchul Roh, Ho-Jang Kwon, Ki Chung Paik, Moo-Yong Rhee, Jae-Yun Jeong, Myung Ho Lim, Mi-Jin Koo, Chang-Hoon Kim, Hae Young Kim, Jeong-Hun Lim, Dong-Hyun Kim
Journal of Preventive Medicine and Public Health.2008; 41(5): 307. CrossRef

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Development of Physiologically Based Pharmacokinetic Model for Several Volatile Organic Compounds: Jae Yeon Jang, Kyung Jong Lee, Ho Keun Chung; Korean Journal of Occupational and Environmental Medicine 1997;9(2):357-377. Published online June 30, 1997; DOI: https://doi.org/10.35371/kjoem.1997.9.2.357

Abstract PDF: Recently physiologically based pharmacokinetic (PB-PK) model has important role in industrial and environmental health. One of problem in application of PB-PK models is that they have uncertainties that is due to different input parameters according to authors. In order to develope a PB-PK model that hag good validity, the effect of several input parameters on simulation results was studies. Chemicals studied were perchloroethylene, toluene and styrene. Simulation of alveolar concentration, blood concentration and urinary metabolites was performed for three solvents, respectively. Input parameters discusses were physiological parameters, metabolic parameters and partition coefficient of chemicals. By comparing simulation results according to several pairs of parameters with experimental data, input parameters that showed best fit were decided.

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Assessment of Cadmium in Blood and Urine of Occupationally Exposed Workers and Renal Dysfunction by Cumulative Exposure Estimate: Seong Kyu Kang, Jeong Sun Yang, Ki Woong Kim, Jae Yeon Jang, Ho Keum Chung; Korean Journal of Occupational and Environmental Medicine 1995;7(1):101-110. Published online February 28, 1995; DOI: https://doi.org/10.35371/kjoem.1995.7.1.101

Abstract PDF

88 workers exposed to cadmium were examined at the 12 factories using or producing cadmium in order to know the present state of cadmium exposure and renal dysfunction in 1992. Cadmium in blood and in urine were measured and compared by the 3 exposure level of cadmium in air. Cadmium in blood of low, moderate and high exposure group were 2.5, 3,8 and 7.6 microgram/L, respectively. Cadmium in urine were 1.8(1.3), 3.8(2,6) and 7.9 microgram/L(6.1 microgram/g creatinine) , resrectively. However, there was no relationship between Urinary cadmium and beta(2)-microglobulin. Cumulative exposure estimate (CEE) was calculated by multiplying the mean ambient cadmium level of the factory and working duration. CEE has a high correlation with cadmium in blood and urine, but no relation to beta(2)-microglobulin. Because working durations were relatively shorter than European workers', the highest CEE was just 300 microgram. year/m(3), which was not enough to induce renal tubular dysfunction. This study, however, suggested the possibility that renal tubular dysfunction caused by cadmium could be happened in Korea in the near future.

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Chronic Cadmium Intoxication and Renal Injury Among Workers of a Small-scale Silver Soldering Company
Won-Jun Choi, Seong-Kyu Kang, Seunghon Ham, Wookyung Chung, Ae Jin Kim, Myunghee Kang
Safety and Health at Work.2020; 11(2): 235. CrossRef

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Assessment of Occupational Exposure to Cadmium in Korea: Seong Kyu Kang, Jeong Pyo Hong, Ki Woong Kim, Jae Yeon Jang, Ho Keun Chung, Kyou Chull Chung; Korean Journal of Occupational and Environmental Medicine 1994;6(2):252-258. Published online September 30, 1994; DOI: https://doi.org/10.35371/kjoem.1994.6.2.252

Abstract PDF

Twenty-four factories registered at the Ministry of Labor as factories using or producing cadmium in 1991 were investigated to know the present state of occupational exposure to cadmium in 1992. Nine factories among 24 stopped using or changed to other substances and 1 factory didn't produce any more, but delivered it to other factories through imports. Therefore, only 14 factories were producing or using cadmium. But, alloying materials were uspplied to about 20 and more factories, however, they couldn't be investigated because of limited information. Three factories had less than 50 workers were 3, 6 had 50-300 and 5 had more than 300. About 167 workers were exposed to cadmium. According to the classification by process, there were 4 alloy processes, 2 refinary, 2 elctroplating, 2 dry cell making, 1 industrial battery and 1 copper refinary. 8 factories used metal cadmium, 3 cadmium oxide, 2 cadmium sulfide, and 1 cadmium hyroxide. One factory was importing cadmium stearates only and supplying them to the PVC making factories. The amount of metal cadmium producing in 2 refinary factories was about 50-65 ton per month. The other cadmium compounds were imported. According to exposure level of cadmium in air of the 10 factories examined, each factory could be divided into high, moderate and low exposure groups. 1 battery recycling factory and 3 alloy factories were in the high exposure group and their mean air concentrations were 0.06679, 0.05481, 0.02492, and 0.003mg/m3, respectively. Refinary and industrial battery making factories were in the middle exposure group and their mean air concentrations were 0.00773 and 0.00613 mg/m3, respectively. Finally, low exposure group were copper smelting, dry cell case making, duplicator drum making and electroplating factory and their mean air concentrations were 0.00096, 0.00071, 0.00057 and 0.00054 mg/m3 respectively.

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Chronic Cadmium Intoxication and Renal Injury Among Workers of a Small-scale Silver Soldering Company
Won-Jun Choi, Seong-Kyu Kang, Seunghon Ham, Wookyung Chung, Ae Jin Kim, Myunghee Kang
Safety and Health at Work.2020; 11(2): 235. CrossRef
The association between cadmium and lead exposure and blood pressure among workers of a smelting industry: a cross-sectional study
Hyun Chan An, Joo Hyun Sung, Jiho Lee, Chang Sun Sim, Sang Hoon Kim, Yangho Kim
Annals of Occupational and Environmental Medicine.2017;[Epub] CrossRef

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Evaluation of biological metabolites among the workers exposed todimethylformanide: Ho Keun Chung, Seong Kyu Kang, Kyung Yong Rhee, Jae Yeon Jang; Korean Journal of Occupational and Environmental Medicine 1992;4(2):144-150. Published online October 31, 1992; DOI: https://doi.org/10.35371/kjoem.1992.4.2.144

Abstract PDF

No abstract available.

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Assessment of correlation between markers of ambient monitoring and biological monitoring of dimethylformamide for workers in synthetic leather manufacturing factories in Korea
Yang In Hwang, Mi-Young Lee, Yun Kyung Chung, Eun A Kim
Analytical Science and Technology.2013; 26(5): 315. CrossRef
Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology
Tae Hyun Kim, Sang Geon Kim
Safety and Health at Work.2011; 2(2): 97. CrossRef

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A study on the liver dysfunction due to dimethylformamide: Seong Kyu Kang, Jae Yeon Jang, Kyung Yong Rhee, Ho Keun Chung; Korean Journal of Occupational and Environmental Medicine 1991;3(1):58-64. Published online February 28, 1991; DOI: https://doi.org/10.35371/kjoem.1991.3.1.58

Abstract PDF

No abstract available.

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Changes of 30 years in the recognized occupational diseases of Korea: Lessons from the system change perspective
Kyung Ehi Zoh, Mijin Park, Domyung Paek
Archives of Environmental & Occupational Health.2020; 75(3): 127. CrossRef
Compensation for Occupational Diseases by Chemical Agents in Korea
Soon-Chan Kwon, Soo-Yong Roh, Ji-Hoon Lee, Eun-A Kim
Journal of Korean Medical Science.2014; 29(Suppl): S78. CrossRef
Compensation for Work-Related Hematologic, Liver, and Infectious Diseases
Jung-Won Kim, Dong-Mug Kang
Journal of Korean Medical Science.2014; 29(Suppl): S66. CrossRef
Assessment of correlation between markers of ambient monitoring and biological monitoring of dimethylformamide for workers in synthetic leather manufacturing factories in Korea
Yang In Hwang, Mi-Young Lee, Yun Kyung Chung, Eun A Kim
Analytical Science and Technology.2013; 26(5): 315. CrossRef
Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology
Tae Hyun Kim, Sang Geon Kim
Safety and Health at Work.2011; 2(2): 97. CrossRef
Occupational Diseases in Korea
Seong-Kyu Kang, Eun A Kim
Journal of Korean Medical Science.2010; 25(Suppl): S4. CrossRef
Grand Rounds: An Outbreak of Toxic Hepatitis among Industrial Waste Disposal Workers
Hae-Kwan Cheong, Eun A Kim, Jung-Keun Choi, Sung-Bong Choi, Jeong-Ill Suh, Dae Seob Choi, Jung Ran Kim
Environmental Health Perspectives.2007; 115(1): 107. CrossRef

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