-
Dermal and neural toxicity caused by acrylamide exposure in two Korean grouting workers: a case report
-
Heeyun Kim, Sang Gil Lee, Jeongbae Rhie
-
Ann Occup Environ Med 2017;29:50. Published online October 9, 2017
-
DOI: https://doi.org/10.1186/s40557-017-0207-7
-
-
Abstract
PDFPubReaderePub
- Background
Peripheral neuritis caused by acrylamide is well-known, and many Korean grouting workers are frequently exposed to acrylamide in grouting agents that are injected into cracked concrete. We recently encountered two cases of dermal and neural toxicity in Korean grouting workers with exposure to grouting agents that contained a high concentration of acrylamide. Case presentationThe first case involved a 44-year-old man with 8 years of waterproofing experience. The patient developed peeling skin on both hands while grouting, which progressed to systemic neurological symptoms, such as reduced sensory function and strength. The patient was diagnosed with peripheral neuropathy caused by acrylamide exposure, and fully recovered after conservative treatment and withdrawal of exposure to the grouting agent. The second case involved a 34-year-old man with 10 years of grouting experience. The patient initially experienced weakness in both legs, which progressed to weakness in his arms and uncontrolled phonation. After being hospitalized, he was diagnosed with cerebellar ataxia and peripheral neuropathy caused by acrylamide exposure, and was discharged after conservative treatment. Our follow-up investigation revealed that both workers were recently exposed to grouting agents that contained higher concentrations of acrylamide, compared to the agents that they had previously been using. ConclusionsBoth workers had workplace acrylamide exposure through dermal contact plus inhalation of dust and vapor, which led to the neural toxicity and dermatitis. Therefore, government studies are needed to investigate the current status of workplace acrylamide use, and to protect workers from the hazardous effects of using acrylamide-containing grouting agents.
-
Citations
Citations to this article as recorded by
- Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to acrylamide (hemoglobin adducts, urinary mercapturic acids) and new insights on its endogenous formation
Bernhard H. Monien, Nick Bergau, Fabian Gauch, Cornelia Weikert, Klaus Abraham Archives of Toxicology.2024; 98(9): 2889. CrossRef - The role of microRNAs in acrylamide toxicity
Mina Homayoonfal, Danial Molavizadeh, Sara Sadeghi, Reza Sharafati Chaleshtori Frontiers in Nutrition.2024;[Epub] CrossRef - Effects of acrylamide on indoor air based on the reactions with O3 and •OH: Mechanism, kinetics, and toxicity evaluation
Xueyu Wang, Sisi Cheng, Guangcai Ma, Xiaoxuan Wei, Jichao Fang, Haiying Yu Journal of Environmental Chemical Engineering.2024; 12(2): 112264. CrossRef - Acrylamide induces neurotoxicity in zebrafish (Danio rerio) via NLRP3-mediated pyroptosis
Boya Zhang, Mengyao Zhao, Xiaoguo Ji, Quanming Xia, Lihua Jiang, Liming Zhao Science of The Total Environment.2023; 896: 165208. CrossRef - Seepage behavior and mechanical properties of two kinds of polyurethane/water glass in combined grouting experiment
Pengcheng Wang, Shuchen Li, Jinglong Li, Huiying Zhou, Pengfei Ma, Ye Tian, Chao Yuan, Xianda Feng Tunnelling and Underground Space Technology.2023; 136: 105092. CrossRef - Effect of long-term exposure to acrylamide on endoplasmic reticulum stress and autophagy in rat cerebellum
Yiqi Wang, Lian Duan, Xing Zhang, Yang Jiao, Ying Liu, Lingling Dai, Hong Yan Ecotoxicology and Environmental Safety.2021; 224: 112691. CrossRef - A Review on Acrylamide in Food: Occurrence, Toxicity, and Mitigation Strategies
Lubna Rifai, Fatima A. Saleh International Journal of Toxicology.2020; 39(2): 93. CrossRef - Risk of exposure to acrylamide
Milena Bušová, Vladimír Bencko, Katarína Veszelits Laktičová, Ivana Holcátová, Mária Vargová Central European Journal of Public Health.2020; 28(Supplement): S43. CrossRef - A new formulation of polymer gel dosimeter with reduced toxicity: Dosimetric characteristics and radiological properties
Abdulrahman Rashidi, Seyed Mohammad Mahdi Abtahi, Elham Saeedzadeh, Mohammad Esmaeil Akbari Zeitschrift für Medizinische Physik.2020; 30(3): 185. CrossRef - Learning, memory deficits, and impaired neuronal maturation attributed to acrylamide
Seulah Lee, Hee Ra Park, Joo Yeon Lee, Jung-Hyun Cho, Hye Min Song, Ah Hyun Kim, Wonjong Lee, Yujeong Lee, Seung-Cheol Chang, Hyung Sik Kim, Jaewon Lee Journal of Toxicology and Environmental Health, Part A.2018; 81(9): 254. CrossRef
-
44
View
-
0
Download
-
15
Web of Science
-
10
Crossref
|